EPS-MAM-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MAM-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	58.1	1.6E-15	110	185	76

Status

Unreviewed

Ensembl Protein

ENSMMUP00000005737

UniProt Accession

F6ZLX4;

Protein Name

Protein Synonyms/Alias

NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial;

Gene Name

PTPMT1

Gene Synonyms/Alias

PTPMT1; NDUFS3; EGK_06287;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000004286	ENSMMUP00000005738	ENSMMUT00000006095
ENSMMUG00000004286	ENSMMUP00000005737	ENSMMUT00000006094
ENSMMUG00000004286	ENSMMUP00000005734	ENSMMUT00000006091

Organism

Macaca mulatta

Functional Description

Protein Length

201

Protein Sequence
(FASTA)

MAATALLEAG LARVLFYPTL LYTLFRGKVP GRAHRDWYHR IDPTVLLGAL PLRSLTRQLV 60

QDENVRGVIT MNEEYETRFL CHSSQEWKRL GVEQLRLSTV DMTGIPTLDN LQKGVQFALK 120

YQSLGQCVYV HCKAGRSRSA TMVAAYLIQV HRWSPEEAVR AIAKIRSYIH IRPGQLDVLK 180

EFHKQVTAGA AKDGTFDTSK T 201

Nucleotide Sequence
(FASTA)

ATGGCGGCCA CCGCGCTGCT GGAGGCCGGC CTGGCGCGGG TGCTCTTCTA CCCGACGCTG 60

CTCTACACCC TGTTCCGCGG GAAGGTGCCG GGTCGGGCGC ACCGGGACTG GTACCACCGC 120

ATCGACCCCA CAGTGCTGCT GGGCGCGCTG CCGTTGCGGA GCTTGACGCG CCAGCTGGTA 180

CAGGACGAGA ACGTGCGCGG GGTGATCACC ATGAACGAGG AGTATGAGAC GAGGTTCCTG 240

TGCCACTCTT CACAGGAGTG GAAGAGACTA GGAGTCGAGC AGCTGCGGCT CAGCACAGTA 300

GACATGACTG GGATCCCTAC CTTGGACAAC CTCCAGAAGG GAGTCCAATT TGCTCTCAAG 360

TACCAGTCGC TGGGCCAGTG TGTCTACGTG CATTGTAAGG CTGGGCGCTC CAGGAGTGCC 420

ACTATGGTGG CAGCATACCT GATTCAGGTG CACAGATGGA GTCCAGAGGA GGCTGTAAGA 480

GCCATCGCCA AGATCCGGTC TTACATCCAC ATCAGGCCTG GCCAGCTGGA TGTTCTTAAA 540

GAGTTCCACA AGCAGGTTAC TGCAGGGGCA GCAAAGGATG GGACTTTTGA CACTTCAAAG 600

ACATGA 606

Domain Profile

S: 71    yfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAieavkrkrpsi  130

          +++ ++f  + ++ g+ v+vHC+aG sRSat+v aYL++v+ +s ++A++a+ + r+ i

Q: 110   NLQKGVQFALKYQSLGQCVYVHCKAGRSRSATMVAAYLIQVHRWSPEEAVRAIAKIRSYI  169

         555666666777888999******************************************

S: 131   epnegfleQLlelekk  146

           + g+l  L e+ k+

Q: 170   HIRPGQLDVLKEFHKQ  185

         *************998

Domain Sequence
(FASTA)

NLQKGVQFAL KYQSLGQCVY VHCKAGRSRS ATMVAAYLIQ VHRWSPEEAV RAIAKIRSYI 60

HIRPGQLDVL KEFHKQ 76

Keyword

Complete proteome; NAD; Oxidoreductase; Reference proteome; Ubiquinone.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005747	; C:mitochondrial respiratory chain complex I
GO:0008137	; F:NADH dehydrogenase (ubiquinone) activity
GO:0006917	; P:induction of apoptosis
GO:0030308	; P:negative regulation of cell growth
GO:0072593	; P:reactive oxygen species metabolic process

KEGG

mcc:713040

;

InterPros

IPR010218	; NADH_DH_suC.
IPR001268	; NADH_UbQ_OxRdtase_30kDa_su.
IPR020396	; NADH_UbQ_OxRdtase_CS.

Pfam

PF00329

; Complex1_30kDa; 1.

SMARTs

Prosites

PS00542

; COMPLEX1_30K; 1.

Prints

Created Date

20-Feb-2013