EKS-MAM-00330

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00330

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	320.6	1.4E-95	66	340	275

Status

Unreviewed

Ensembl Protein

ENSMMUP00000008170

UniProt Accession

F7HLJ1;

Protein Name

Protein Synonyms/Alias

Gene Name

STK39

Gene Synonyms/Alias

STK39;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000006215	ENSMMUP00000008170	ENSMMUT00000008694

Organism

Macaca mulatta

Functional Description

Protein Length

548

Protein Sequence
(FASTA)

MAEPSGSPVH VQLPQQAAPV TAAATAPAAA TAAPAPAAPA APAPAPAPAP APAAQAVGWP 60

ICRDAYELQE VIGSGATAVV QAALCKPRQE RVAIKRINLE KCQTSMDELL KEIQAMSQCS 120

HPNVVTYYTS FVVKDELWLV MKLLSGGSML DIIKYIVNRG EHKNGVLEEA IIATILKEVL 180

EGLDYLHRNG QIHRDLKAGN ILLGEDGSVQ IADFGVSAFL ATGGDVTRNK VRKTFVGTPC 240

WMAPEVMEQV RGYDFKADMW SFGITAIELA TGAAPYHKYP PMKVLMLTLQ NDPPTLETGV 300

EDKEMMKKYG KSFRKLLSLC LQKDPSKRPT AAELLKCKFF QKAKNREYLI EKLLTRTPDI 360

AQRAKKVRRV PGSSGHLHKT EDGDWEWSDD EMDEKSEEGK AAFSQEKSRR VKEENPEIAV 420

NASTIPEQIQ SLSVHDSQSP PSANEDYREA ASCAVNLVLR LRNSRKELND IRFEFTPGRD 480

TADGVSQELF SAGLVDGHDV VIVAANLQKI VDDPKALKTL TFKLASGCDG SEIPDEVKLI 540

GFAQLSVS 548

Nucleotide Sequence
(FASTA)

ATGGCGGAGC CGAGTGGCTC GCCCGTGCAC GTCCAGCTTC CCCAGCAGGC GGCCCCGGTG 60

ACAGCGGCGG CGACGGCCCC AGCGGCCGCG ACAGCAGCGC CGGCCCCAGC AGCTCCCGCG 120

GCCCCGGCCC CGGCCCCGGC CCCAGCCCCA GCCCCGGCGG CACAGGCTGT GGGCTGGCCC 180

ATCTGCAGGG ACGCGTACGA GCTGCAGGAG GTTATCGGCA GTGGAGCTAC TGCTGTGGTT 240

CAAGCAGCCC TATGCAAACC CAGGCAAGAA CGTGTAGCAA TAAAACGGAT CAACTTGGAA 300

AAATGCCAGA CCAGTATGGA TGAACTATTA AAAGAAATTC AAGCCATGAG TCAGTGCAGC 360

CATCCCAACG TAGTGACCTA TTACACCTCT TTTGTGGTCA AAGATGAACT TTGGCTGGTC 420

ATGAAATTAC TAAGCGGAGG TTCAATGTTG GATATCATAA AATACATTGT CAACCGAGGA 480

GAACACAAGA ACGGAGTTCT GGAAGAGGCA ATAATAGCAA CAATTCTTAA AGAAGTTTTG 540

GAAGGCTTAG ACTATCTACA CAGAAATGGT CAGATTCACA GGGATTTGAA AGCTGGTAAT 600

ATTCTTCTGG GTGAGGATGG TTCAGTACAA ATAGCAGATT TTGGAGTAAG TGCGTTCCTA 660

GCAACAGGGG GTGATGTTAC CCGAAATAAA GTAAGAAAAA CATTCGTTGG CACCCCATGT 720

TGGATGGCCC CTGAAGTCAT GGAACAGGTG AGAGGCTATG ACTTCAAGGC TGACATGTGG 780

AGTTTTGGAA TAACTGCCAT TGAGTTAGCA ACAGGAGCAG CGCCTTATCA CAAATATCCT 840

CCCATGAAAG TGTTAATGTT GACTTTGCAA AATGATCCAC CCACTTTGGA AACAGGGGTA 900

GAGGATAAAG AAATGATGAA AAAGTACGGC AAGTCCTTTA GAAAATTACT TTCACTGTGT 960

CTTCAGAAAG ATCCTTCCAA AAGGCCCACA GCAGCAGAAC TTTTAAAATG CAAATTCTTC 1020

CAGAAGGCCA AGAACAGAGA GTACCTGATT GAGAAGCTGC TTACAAGAAC ACCAGACATA 1080

GCCCAAAGAG CCAAAAAGGT AAGAAGAGTT CCTGGGTCAA GTGGTCACCT TCATAAAACC 1140

GAAGATGGGG ACTGGGAGTG GAGTGATGAT GAGATGGATG AGAAGAGCGA AGAAGGGAAA 1200

GCAGCTTTTT CTCAGGAAAA GTCACGAAGA GTAAAAGAAG AAAATCCAGA GATTGCAGTG 1260

AACGCCAGCA CCATCCCTGA ACAAATACAG TCCCTGTCTG TGCATGACTC TCAGAGTCCA 1320

CCCAGTGCTA ATGAAGACTA CAGAGAAGCT GCTTCTTGCG CTGTGAACCT CGTTTTGAGA 1380

TTAAGAAACT CCAGAAAGGA ACTTAATGAC ATACGATTTG AGTTTACTCC AGGAAGAGAT 1440

ACAGCAGATG GTGTATCTCA GGAGCTCTTC TCTGCTGGCT TGGTGGATGG TCACGATGTA 1500

GTTATAGTGG CTGCTAATTT ACAGAAGATT GTAGATGATC CCAAAGCTTT AAAAACATTG 1560

ACATTTAAGT TGGCGTCTGG CTGTGATGGG TCGGAGATTC CTGACGAAGT GAAGCTGATT 1620

GGGTTTGCTC AGTTGAGTGT CAGCTGA 1647

Domain Profile

S: 1     yelleeigkGalgkvylarekktgelvaikkinlekq.ekleelqkeisvlkklkhpniv  59

         yel+e+ig+Ga++ v++a +k+++e vaik+inlek+ ++++el kei+++++++hpn+v

Q: 66    YELQEVIGSGATAVVQAALCKPRQERVAIKRINLEKCqTSMDELLKEIQAMSQCSHPNVV  125

         99***********************************8899*******************

S: 60    eylesflkeeelwlvmeylagGslsdlvk......eelkselkEeqiayilrevlkaLey  113

         +y++sf++++elwlvm++l+gGs+ d++k      e+++  l+E  ia+il+evl++L+y

Q: 126   TYYTSFVVKDELWLVMKLLSGGSMLDIIKyivnrgEHKNGVLEEAIIATILKEVLEGLDY  185

         **********************************999***********************

S: 114   lHskkviHrdikakniLlteegeVkLsdfgvaaqlek....trkk.rktvvgtpywmAPE  168

         lH++++iHrd+ka+niLl e+g+V+++dfgv+a l++    tr+k rkt+vgtp+wmAPE

Q: 186   LHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATggdvTRNKvRKTFVGTPCWMAPE  245

         ***********************************99888888899**************

S: 169   viaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk.....  223

         v++q  +gYd kaD+ws+GItaiela+g++P+++++p+k+l+++l+n+pp+l++

Q: 246   VMEQ-VRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGvedke  304

         ***5.9**********************************************66666777

S: 224   ..kkfskefkefvekclqknpekRpsasellkhkFl  257

           kk++k+f+++++ clqk+p+kRp+a+ellk kF+

Q: 305   mmKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFF  340

         7799******************************97

Domain Sequence
(FASTA)

YELQEVIGSG ATAVVQAALC KPRQERVAIK RINLEKCQTS MDELLKEIQA MSQCSHPNVV 60

TYYTSFVVKD ELWLVMKLLS GGSMLDIIKY IVNRGEHKNG VLEEAIIATI LKEVLEGLDY 120

LHRNGQIHRD LKAGNILLGE DGSVQIADFG VSAFLATGGD VTRNKVRKTF VGTPCWMAPE 180

VMEQVRGYDF KADMWSFGIT AIELATGAAP YHKYPPMKVL MLTLQNDPPT LETGVEDKEM 240

MKKYGKSFRK LLSLCLQKDP SKRPTAAELL KCKFF 275

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016324	; C:apical plasma membrane
GO:0016323	; C:basolateral plasma membrane
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity

KEGG

mcc:704855

;

InterPros

IPR011009	; Kinase-like_dom.
IPR024678	; Kinase_OSR1/WNK_CCT.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.

Pfam

PF12202	; OSR1_C; 1.
PF00069	; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013