EPS-MAM-00060

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MAM-00060

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PTEN	293.4	1.4E-87	132	308	177

Status

Unreviewed

Ensembl Protein

ENSMMUP00000009681

UniProt Accession

F7E4U2;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC704870

Gene Synonyms/Alias

LOC704870;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000007379	ENSMMUP00000009681	ENSMMUT00000010319
ENSMMUG00000007379	ENSMMUP00000009683	ENSMMUT00000010321
ENSMMUG00000007379	ENSMMUP00000009684	ENSMMUT00000010322

Organism

Macaca mulatta

Functional Description

Protein Length

444

Protein Sequence
(FASTA)

SASTQTNEFK GATKETLTIE TPHSSECKGA GLLSPVSKRI FGVFLVLLDV TLLLADLIFN 60

DSKLYIPLVY RSISLAIALF FLMDVLLRVF VEGWIHLVRL LRLIILIRIF HLIHQKRELE 120

KLMRRLVSEN KRRYTRDGFD LDLTYVTERI IAMSFPSSGR QSFYRNPIEE VVRFLDKKHP 180

NHYRVYNLCS ERAYDPKYFH NRVSRIMIDD HNVPTLHEMV VFTKEVNEWM AQDPANIVAI 240

HCKGGKGRTG TMICAFLIAS EIFLTAEESL YYFGERRTDK TNSSKFQGVE TPSQNRYVGY 300

FAQVKHLYNW NLPPRRILFI KRFIIYSIRG GVCDLKVRIV MEKKVVFSST SLGNCSILHD 360

IETDRVLIDV FSGPPLYDDV KVQFFSSNLP KYYDNCPFFF WFNTSFIQSN RLYLPRNELD 420

NPHKQKTWKI YPPQFAVEVL FGEK 444

Nucleotide Sequence
(FASTA)

TCTGCTAGTA CACAGACAAA TGAATTTAAA GGAGCAACCA AGGAGACACT TACGATTGAA 60

ACCCCACACA GCAGTGAATG TAAAGGAGCA GGCCTGTTGT CACCTGTCAG TAAAAGAATA 120

TTTGGAGTCT TCCTGGTCTT ACTGGATGTC ACTCTCCTCC TTGCCGACCT AATTTTCAAT 180

GATAGCAAAC TTTATATTCC TTTGGTGTAT CGTTCTATTT CTCTAGCTAT TGCCTTATTT 240

TTTCTCATGG ATGTTCTTCT TCGAGTATTT GTTGAAGGAT GGATACATTT AGTTCGACTT 300

CTACGACTTA TTATTCTGAT AAGAATTTTT CATCTGATTC ATCAAAAAAG AGAACTTGAA 360

AAGCTGATGA GAAGGCTGGT TTCAGAAAAC AAAAGGCGAT ACACAAGGGA TGGATTTGAC 420

CTAGACCTCA CTTATGTTAC AGAACGTATT ATCGCTATGT CATTTCCATC TTCTGGAAGG 480

CAGTCTTTCT ATAGAAATCC AATTGAGGAA GTCGTGCGGT TTCTAGATAA GAAACATCCA 540

AATCACTATC GAGTCTATAA TCTATGCAGT GAAAGAGCTT ATGATCCTAA GTACTTCCAT 600

AATAGGGTCA GTAGAATCAT GATTGATGAT CATAATGTCC CCACTCTACA TGAGATGGTG 660

GTTTTCACCA AGGAAGTAAA TGAGTGGATG GCTCAAGATC CTGCAAACAT CGTAGCAATT 720

CACTGTAAAG GAGGCAAAGG AAGAACTGGA ACTATGATTT GTGCCTTCCT TATTGCCTCC 780

GAAATATTTT TAACTGCAGA GGAAAGCCTA TATTATTTTG GAGAAAGGCG AACAGATAAA 840

ACCAACAGCA GTAAATTTCA GGGAGTAGAA ACTCCTTCTC AGAATAGATA TGTTGGATAT 900

TTTGCACAAG TGAAACATCT CTACAACTGG AATCTCCCCC CGAGACGGAT ACTCTTTATA 960

AAAAGATTCA TTATTTATTC GATTCGTGGC GGTGTATGTG ATCTAAAAGT CCGAATAGTA 1020

ATGGAGAAAA AAGTTGTCTT TTCCAGTACT TCATTAGGAA ATTGTTCGAT ATTGCATGAC 1080

ATTGAAACAG ACAGAGTGTT AATTGATGTA TTCAGCGGTC CCCCTCTGTA TGACGACGTG 1140

AAGGTACAGT TTTTCTCTTC GAATCTTCCT AAATACTATG ACAATTGTCC GTTTTTCTTC 1200

TGGTTCAACA CATCTTTTAT TCAAAGTAAC AGGCTTTATC TACCAAGAAA TGAATTGGAT 1260

AATCCACATA AACAAAAAAC ATGGAAAATT TATCCACCAC AATTTGCAGT GGAGGTACTT 1320

TTTGGTGAGA AGTGA 1335

Domain Profile

S: 1     rrltedgfdldltyvteriiavsfPaeareevyrnnlrevvrlldskhrnkyklynlcse  60

         rr+t+dgfdldltyvteriia+sfP+++r+++yrn+++evvr+ld+kh n+y++ynlcse

Q: 132   RRYTRDGFDLDLTYVTERIIAMSFPSSGRQSFYRNPIEEVVRFLDKKHPNHYRVYNLCSE  191

         79**********************************************************

S: 61    rrydltklnakvaefgiedlnaPaleklvsickeldeWlseddenvvvlhckggkgrlGv  120

         r+yd++ ++++v++++i+d+n+P+l+++v+++ke++eW+++d+ n+v++hckggkgr+G+

Q: 192   RAYDPKYFHNRVSRIMIDDHNVPTLHEMVVFTKEVNEWMAQDPANIVAIHCKGGKGRTGT  251

         ************************************************************

S: 121   ivcayllaseisakadealdtfgerr...tredkvagvkqPsqrryvsyfsqllkgs  174

         ++ca+l+asei+++a+e+l++fgerr   t + k++gv++Psq+ryv yf+q+++++

Q: 252   MICAFLIASEIFLTAEESLYYFGERRtdkTNSSKFQGVETPSQNRYVGYFAQVKHLY  308

         *************************9888899**********************975

Domain Sequence
(FASTA)

RRYTRDGFDL DLTYVTERII AMSFPSSGRQ SFYRNPIEEV VRFLDKKHPN HYRVYNLCSE 60

RAYDPKYFHN RVSRIMIDDH NVPTLHEMVV FTKEVNEWMA QDPANIVAIH CKGGKGRTGT 120

MICAFLIASE IFLTAEESLY YFGERRTDKT NSSKFQGVET PSQNRYVGYF AQVKHLY 177

Keyword

Complete proteome; Ion transport; Ionic channel; Membrane; Reference proteome; Transmembrane; Transport.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016021	; C:integral to membrane
GO:0005216	; F:ion channel activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR008973	; C2_Ca/lipid-bd_dom_CaLB.
IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR005821	; Ion_trans_dom.
IPR014019	; Phosphatase_tensin-typ.
IPR014020	; Tensin_phosphatase_C2-dom.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782	; DSPc; 1.
PF00520	; Ion_trans; 1.
PF10409	; PTEN_C2; 1.

SMARTs

Prosites

PS51182	; C2_TENSIN; 1.
PS51181	; PPASE_TENSIN; 1.
PS00383	; TYR_PHOSPHATASE_1; 1.

Prints

Created Date

20-Feb-2013