EKS-MAM-00121

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00121

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PSK	531.2	6.9E-160	98	355	258

Status

Unreviewed

Ensembl Protein

ENSMMUP00000015613

UniProt Accession

F7HN09;

Protein Name

Protein Synonyms/Alias

Serine/threonine-protein kinase H1;

Gene Name

PSKH1

Gene Synonyms/Alias

PSKH1; EGK_12911;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000011895	ENSMMUP00000015613	ENSMMUT00000016668

Organism

Macaca mulatta

Functional Description

Protein Length

424

Protein Sequence
(FASTA)

MGCGTSKVLP EPPKDVQLDL VKKVEPFSGT KSDVYKHFIT EVDSVGPVKA GFPAASQYAH 60

PCPSPPTAGH TEPPSEPPRR ARVAKYRAKF DPRVTAKYDI KALIGRGSFS RVVRVEHRAT 120

RQPYAIKMIE TKYREGREVC ESELRVLRRV RHANIIQLVE VFETQERVYM VMELATGGEL 180

FDRIIAKGSF TERDATRVLQ MVLDGVRYLH ALGITHRDLK PENLLYYHPG TDSKIIITDF 240

GLASARKKGD DCLMKTTCGT PEYIAPEVLV RKPYTNSVDM WALGVIAYIL LSGTMPFEDD 300

NRTRLYRQIL RGKYSYSGEP WPSVSNLAKD FIDRLLTVDP GARMTALQAL RHPWVVSMAA 360

SSSMKNLHRS ISQNLLKRAS SRCQSTKSAQ STRSSRSTRS NKSRRVRERE LRELNLRYQQ 420

QYNG 424

Nucleotide Sequence
(FASTA)

ATGGGCTGTG GGACAAGCAA GGTACTTCCC GAGCCACCCA AGGATGTCCA GCTGGATCTG 60

GTCAAGAAGG TGGAGCCCTT CAGTGGCACT AAGAGTGATG TGTACAAGCA CTTCATCACA 120

GAGGTGGACA GTGTTGGCCC TGTCAAAGCT GGGTTCCCAG CAGCAAGTCA GTATGCACAC 180

CCCTGTCCCA GTCCCCCGAC TGCTGGCCAC ACGGAGCCTC CCTCAGAACC ACCACGCAGG 240

GCCAGGGTAG CTAAGTACAG GGCCAAGTTT GACCCACGTG TGACAGCTAA GTATGACATC 300

AAGGCCCTAA TTGGCCGAGG CAGCTTCAGC CGAGTGGTAC GTGTAGAGCA CCGGGCAACC 360

CGGCAGCCAT ATGCCATCAA GATGATTGAG ACCAAGTACC GGGAGGGACG GGAGGTGTGT 420

GAGTCGGAGC TGCGTGTGCT GCGTCGGGTG CGTCATGCTA ATATCATCCA GCTGGTGGAG 480

GTGTTCGAGA CGCAGGAGCG GGTGTACATG GTGATGGAGC TGGCCACTGG TGGAGAGCTC 540

TTCGACCGCA TCATTGCCAA GGGCTCCTTC ACCGAGCGTG ATGCCACACG GGTGCTACAG 600

ATGGTGCTGG ATGGCGTCCG GTATCTGCAC GCACTGGGCA TCACACACCG AGACCTCAAA 660

CCTGAGAATC TGCTCTACTA CCATCCAGGC ACTGACTCTA AGATCATCAT CACCGACTTT 720

GGCCTGGCCA GTGCTCGCAA GAAGGGTGAC GACTGCTTGA TGAAGACCAC CTGTGGCACG 780

CCTGAGTACA TTGCCCCAGA AGTCCTGGTC CGCAAGCCCT ACACCAACTC AGTGGACATG 840

TGGGCGCTGG GCGTCATTGC CTACATCCTA CTCAGTGGCA CCATGCCGTT TGAGGACGAC 900

AACCGTACCC GGCTGTACCG GCAGATCCTC AGGGGCAAGT ACAGTTACTC TGGGGAGCCC 960

TGGCCTAGTG TGTCCAACCT GGCCAAGGAC TTCATTGACC GCCTGCTGAC GGTGGACCCT 1020

GGAGCCCGTA TGACTGCACT GCAGGCCCTG AGGCACCCGT GGGTGGTGAG CATGGCTGCC 1080

TCTTCATCCA TGAAGAACCT GCACCGCTCC ATATCCCAGA ACCTCCTCAA ACGTGCCTCC 1140

TCGCGCTGCC AGAGCACCAA ATCTGCCCAG TCCACGCGTT CCAGCCGCTC CACACGCTCC 1200

AACAAGTCAC GCCGTGTGCG GGAGCGGGAG CTGCGGGAGC TCAACCTGCG CTACCAACAG 1260

CAGTACAATG GCTGA 1275

Domain Profile

S: 1     ydikaligkgsfsrvvrvehratrkpfaikvvetkeregreaveselrvlrrvshafiiq  60

         ydikalig+gsfsrvvrvehratr+p+aik++etk+regre++eselrvlrrv+ha+iiq

Q: 98    YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQ  157

         9***********************************************************

S: 61    lvevfeteekvylvmelatggelfdrviakgsfterdatrvlkmvldgvrylhalrithr  120

         lvevfet+e+vy+vmelatggelfdr+iakgsfterdatrvl+mvldgvrylhal+ithr

Q: 158   LVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHR  217

         ************************************************************

S: 121   dlkpenllyydpgeeskilitdfglayaakksddllmkttcgtpeyiapevllrkpytns  180

         dlkpenllyy+pg++ski+itdfgla+a+kk+dd+lmkttcgtpeyiapevl+rkpytns

Q: 218   DLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNS  277

         ************************************************************

S: 181   vdmwalgviayillsgilpfdddsrtrlyrkilkgkysylgepwpsvselakdfidklle  240

         vdmwalgviayillsg++pf+dd+rtrlyr+il+gkysy+gepwpsvs+lakdfid+ll+

Q: 278   VDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLT  337

         ************************************************************

S: 241   vdagerlsasqalkhewv  258

         vd+g+r++a+qal+h+wv

Q: 338   VDPGARMTALQALRHPWV  355

         *****************8

Domain Sequence
(FASTA)

YDIKALIGRG SFSRVVRVEH RATRQPYAIK MIETKYREGR EVCESELRVL RRVRHANIIQ 60

LVEVFETQER VYMVMELATG GELFDRIIAK GSFTERDATR VLQMVLDGVR YLHALGITHR 120

DLKPENLLYY HPGTDSKIII TDFGLASARK KGDDCLMKTT CGTPEYIAPE VLVRKPYTNS 180

VDMWALGVIA YILLSGTMPF EDDNRTRLYR QILRGKYSYS GEPWPSVSNL AKDFIDRLLT 240

VDPGARMTAL QALRHPWV 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

mcc:700845

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013