EKS-MAM-00494

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00494

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/TIF1	N/A	N/A	N/A	N/A	N/A

Status

Unreviewed

Ensembl Protein

ENSMMUP00000019188

UniProt Accession

F7GNI0;

Protein Name

Protein Synonyms/Alias

Gene Name

TRIM33

Gene Synonyms/Alias

TRIM33;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000014620	ENSMMUP00000019190	ENSMMUT00000020505
ENSMMUG00000014620	ENSMMUP00000019188	ENSMMUT00000020503

Organism

Macaca mulatta

Functional Description

Protein Length

1127

Protein Sequence
(FASTA)

MAENKGGGEA ESGGGGSGSA PVTAGAAGPA EQEAEPPLTA KKVEEEEEEG GRAGAEGGAA 60

GPDDGGVAAA SSGSAQAASS PAASVGPAVP GGAVSTPAPA PASAPAPGPS AGPPPGPPAS 120

LLDTCAVCQQ SLQSRREAEP KLLPCLHSFC LRCLPEPERQ LSVPIPGGSN GDIQQVGVIR 180

CPVCRQECRQ IDLVDNYFVK DTSEAPSSSD EKSEQVCTSC EDNASAVGFC VECGEWLCKT 240

CIEAHQRVKF TKDHLIRKKE DVSESVGASG QRPVFCPVHK QEQLKLFCET CDRLTCRDCQ 300

LLEHKEHRYQ FLEEAFQNQK GAIENLLAKL LEKKNYVHFA ATQVQNRIKE VNETNKRVEQ 360

EIKVAIFTLI NEINKKGKSL LQQLENVTKE RQMKLLQQQN DITGLSRQVK HVMNFTNWAI 420

ASGSSTALLY SKRLITFQLR HILKARCDPV PAANGAIRFH CDPTFWAKNV VNLGNLVIES 480

KPTPGYTPNV VVGQVPPGTN HISKTPGQIN LAQLRLQHMQ QQVYAQKHQQ LQQMRMQQPP 540

APVPTTTTTT QQHPRQAAPQ MLQQQPPRLI SVQTMQRGNM NCGAFQAHQM RLAQNAARIP 600

GIPRHSSPQY SMMQPHLQRQ HSNPGHAGPF PVVSVHNTTI NPTSPTTATM ANANRGPTSP 660

SVTAIELIPS VTNPENLPSL PDIPPIQLED AGSSSLDNLL SRYISGSHLP PQPTSTMNPS 720

PGPSALSPGS SGLSNSHTPV RPPSTSSTGS RGSCGSSGRT AEKTSLSFKS DQVKVKQEPG 780

TEDEICSFSG GVKQEKTEDG RRSACMLSSP ESSLTPPLST NLHLESELDA LASLENHVKT 840

EPADMNESCK QSGLSSLVNG KSPIRSLMHR SARIGGDGNN KDDDPNEDWC AVCQNGGDLL 900

CCEKCPKVFH LTCHVPTLLS FPSGDWICTF CRDIGKPEVE YDCDNLQHSK KGKTAQGLSP 960

VDQRKCERLL LYLYCHELSI EFQEPVPASI PNYYKIIKKP MDLSTVKKKL QKKHSQHYQI 1020

PDDFVADVRL IFKNCERFNE MMKVVQVYAD TQEINLKADS EVAQAGKAVA LYFEDKLTEI 1080

YSDRTFAPLP EFEQEEDDGE VTEDSDEDFI QPRRKRLKSD ERPVHIK 1127

Nucleotide Sequence
(FASTA)

ATGGCGGAAA ACAAAGGCGG CGGCGAGGCT GAGAGCGGCG GCGGGGGCAG CGGCAGCGCG 60

CCGGTAACTG CTGGGGCCGC CGGGCCCGCG GAGCAGGAGG CGGAGCCGCC TCTCACCGCG 120

AAAAAGGTGG AGGAGGAGGA GGAGGAAGGC GGCAGGGCCG GCGCTGAGGG CGGCGCGGCC 180

GGGCCCGACG ACGGGGGGGT GGCCGCGGCC TCCTCGGGCT CTGCCCAGGC TGCTTCATCC 240

CCTGCGGCCT CAGTGGGCCC TGCAGTTCCC GGGGGCGCGG TATCGACACC GGCTCCAGCT 300

CCAGCCTCGG CTCCCGCTCC GGGTCCCTCG GCGGGGCCGC CTCCTGGACC GCCAGCCTCG 360

CTCCTGGACA CCTGCGCCGT GTGTCAGCAG AGCTTGCAGA GCCGGCGTGA GGCGGAGCCC 420

AAGCTGCTGC CCTGTCTTCA CTCCTTCTGC CTGCGCTGCC TGCCGGAGCC GGAGCGCCAG 480

CTCAGCGTGC CCATCCCGGG GGGCAGCAAC GGCGACATCC AGCAAGTTGG TGTAATACGG 540

TGCCCAGTAT GCCGCCAAGA ATGCAGACAG ATAGACCTTG TGGATAATTA TTTTGTGAAA 600

GACACATCTG AAGCTCCTAG CAGTTCTGAT GAAAAATCAG AACAGGTATG TACTAGTTGT 660

GAAGACAATG CAAGTGCAGT TGGCTTTTGT GTAGAATGTG GAGAGTGGCT ATGTAAGACA 720

TGTATCGAAG CACATCAAAG AGTAAAATTT ACTAAAGATC ACTTGATCAG GAAGAAAGAA 780

GATGTCTCAG AGTCTGTCGG AGCATCTGGT CAACGCCCTG TTTTCTGCCC TGTACACAAA 840

CAAGAACAGT TGAAACTTTT CTGTGAAACA TGTGATAGAC TGACATGTAG AGACTGTCAG 900

CTATTGGAAC ACAAAGAACA TAGGTATCAG TTTTTGGAAG AAGCTTTTCA AAATCAGAAA 960

GGTGCAATTG AGAATCTACT GGCTAAACTT CTTGAGAAGA AGAATTATGT TCATTTTGCA 1020

GCCACTCAGG TGCAGAATAG GATAAAAGAA GTAAATGAGA CTAACAAACG AGTAGAACAG 1080

GAAATTAAAG TGGCCATTTT CACCCTTATC AATGAAATTA ATAAGAAAGG AAAATCTCTC 1140

TTACAGCAGC TAGAGAATGT TACAAAGGAA AGACAGATGA AGTTACTACA GCAGCAGAAT 1200

GACATCACAG GCCTTTCCCG GCAGGTGAAG CATGTTATGA ACTTCACAAA TTGGGCAATT 1260

GCAAGTGGCA GCAGCACAGC ACTACTGTAC AGCAAGCGAC TGATTACTTT CCAGTTGCGT 1320

CATATTTTGA AAGCACGGTG TGATCCTGTC CCTGCTGCTA ACGGAGCAAT ACGTTTCCAT 1380

TGTGATCCCA CCTTCTGGGC AAAGAATGTA GTCAATTTAG GTAATCTAGT AATAGAGAGT 1440

AAACCAACTC CTGGTTATAC TCCTAATGTT GTAGTTGGGC AAGTTCCTCC AGGGACAAAC 1500

CACATTAGTA AAACCCCTGG ACAGATTAAC TTAGCACAGC TTCGACTTCA GCACATGCAA 1560

CAACAAGTGT ATGCACAGAA ACATCAGCAG TTGCAACAGA TGAGGATGCA GCAACCACCA 1620

GCACCTGTAC CAACTACAAC AACAACAACA CAACAGCATC CTAGACAAGC AGCCCCTCAG 1680

ATGTTACAAC AACAGCCTCC TCGATTGATC AGTGTGCAAA CAATGCAAAG AGGCAACATG 1740

AACTGTGGAG CTTTTCAAGC CCATCAGATG AGACTCGCTC AGAATGCTGC CAGAATACCA 1800

GGGATACCCA GGCACAGCAG CCCTCAGTAT TCCATGATGC AGCCACACCT CCAAAGACAA 1860

CACTCAAACC CAGGGCATGC TGGACCCTTT CCTGTAGTAT CGGTACACAA CACCACAATC 1920

AACCCAACGA GCCCTACTAC AGCAACTATG GCAAATGCAA ACCGAGGTCC CACCAGCCCA 1980

TCTGTTACAG CAATAGAGCT AATCCCCTCA GTTACCAATC CAGAGAACCT TCCATCGCTG 2040

CCAGATATTC CACCCATACA GTTGGAAGAT GCTGGCTCAA GTAGTTTAGA TAATCTACTA 2100

AGTAGATACA TCTCAGGCAG TCACCTACCC CCACAGCCTA CAAGCACCAT GAATCCCTCC 2160

CCAGGACCCT CTGCCCTTTC TCCGGGATCA TCAGGTTTAT CCAATTCTCA CACACCTGTG 2220

AGACCCCCAA GTACTTCTAG TACTGGCAGT CGAGGCAGCT GTGGCTCATC AGGAAGAACT 2280

GCTGAGAAGA CAAGTCTTAG TTTCAAATCT GATCAGGTGA AGGTCAAGCA AGAACCTGGG 2340

ACTGAAGATG AAATATGTAG CTTTTCAGGA GGTGTAAAAC AAGAAAAAAC AGAGGATGGC 2400

AGGAGGAGTG CTTGCATGTT GAGCAGTCCT GAGAGTAGCT TGACACCACC TCTCTCAACC 2460

AACCTGCATC TAGAAAGTGA GTTGGATGCA TTGGCAAGCC TGGAAAACCA TGTGAAAACT 2520

GAACCTGCAG ATATGAATGA AAGCTGCAAA CAGTCAGGGC TCAGCAGCCT TGTTAATGGA 2580

AAGTCCCCAA TTCGAAGCCT CATGCACAGG TCGGCAAGGA TTGGAGGAGA TGGCAACAAT 2640

AAAGATGATG ACCCAAATGA AGACTGGTGT GCTGTCTGCC AAAATGGAGG AGATCTCTTG 2700

TGCTGCGAAA AATGTCCAAA GGTCTTTCAT CTAACTTGTC ATGTTCCAAC ACTACTTAGC 2760

TTTCCAAGTG GGGACTGGAT ATGCACATTT TGTAGAGATA TTGGAAAGCC AGAAGTTGAA 2820

TACGATTGTG ATAATTTGCA ACATAGTAAG AAGGGGAAAA CTGCACAGGG GTTAAGCCCC 2880

GTGGACCAAA GGAAATGTGA ACGTCTTCTG CTTTACCTCT ATTGCCATGA ATTAAGTATT 2940

GAATTCCAGG AGCCTGTTCC TGCTTCGATA CCAAACTACT ATAAAATTAT AAAGAAACCA 3000

ATGGATTTAT CCACCGTGAA AAAGAAGCTT CAGAAAAAAC ATTCCCAACA CTACCAAATC 3060

CCAGATGACT TTGTGGCTGA TGTCCGTTTG ATCTTCAAGA ACTGTGAAAG GTTTAATGAA 3120

ATGATGAAAG TTGTTCAAGT TTATGCAGAC ACACAAGAGA TTAATTTGAA GGCTGATTCA 3180

GAAGTAGCTC AGGCAGGGAA AGCAGTTGCA TTGTACTTTG AAGATAAACT CACAGAGATC 3240

TACTCAGACA GGACCTTCGC ACCTTTGCCA GAGTTTGAGC AGGAAGAGGA TGATGGTGAG 3300

GTAACTGAGG ACTCTGATGA AGACTTTATA CAGCCCCGCA GAAAACGCCT AAAGTCAGAT 3360

GAGAGACCAG TACATATAAA GTAA 3384

Domain Profile

N/A

Domain Sequence
(FASTA)

N/A

Keyword

Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0008270	; F:zinc ion binding
GO:0030514	; P:negative regulation of BMP signaling pathway
GO:0017015	; P:regulation of transforming growth factor beta receptor signaling pathway

KEGG

InterPros

IPR003649	; Bbox_C.
IPR001487	; Bromodomain.
IPR019786	; Zinc_finger_PHD-type_CS.
IPR000315	; Znf_B-box.
IPR011011	; Znf_FYVE_PHD.
IPR001965	; Znf_PHD.
IPR019787	; Znf_PHD-finger.
IPR001841	; Znf_RING.
IPR013083	; Znf_RING/FYVE/PHD.
IPR017907	; Znf_RING_CS.

Pfam

PF00439	; Bromodomain; 1.
PF00628	; PHD; 1.
PF00643	; zf-B_box; 2.
PF13639	; zf-RING_2; 1.

SMARTs

SM00502	; BBC; 1.
SM00336	; BBOX; 2.
SM00297	; BROMO; 1.
SM00249	; PHD; 2.
SM00184	; RING; 2.

Prosites

PS50014	; BROMODOMAIN_2; 1.
PS50119	; ZF_BBOX; 2.
PS01359	; ZF_PHD_1; 1.
PS50016	; ZF_PHD_2; 1.
PS00518	; ZF_RING_1; 1.
PS50089	; ZF_RING_2; 1.

Prints

PR00503

; BROMODOMAIN.

Created Date

20-Feb-2013