EKS-MAM-00141

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00141

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/RIO	301.5	6.7E-90	180	393	214

Status

Unreviewed

Ensembl Protein

ENSMMUP00000020436

UniProt Accession

F6PZN3;

Protein Name

Serine/threonine-protein kinase RIO1

Protein Synonyms/Alias

Gene Name

RIOK1

Gene Synonyms/Alias

RIOK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000015577	ENSMMUP00000020436	ENSMMUT00000021850

Organism

Macaca mulatta

Functional Description

Protein Length

564

Protein Sequence
(FASTA)

MDYRRFLMSR VVPGQFDDAD SSDSENRNLK TVREKDDILF ENLQDNVNEN GEGEIEDEEE 60

DGYDDDDDWD WDEGVGKVTK GYVWNGGSNP QANRQTSDSS SAKMSTPADK VLRKFENKIN 120

LDKLNVTDSV INKVTEKSRQ KEADMYRIKD KADRATVEQV LDPRTRMILF KMLTRGIITE 180

INGCISTGKE ANVYHASTAD GESRAIKIYK TSILVFKDRD KYVSGEFRFR HGYCKGNPRK 240

MVKTWAEKEM RNLIRLNTAE IPCPEPIMLR IETGSFSFHS RPAPLLKNVQ LPESKARELY 300

LQVIQYMRRM YQDARLVHAD LSEFNMLYHA GGVYIIDVSQ SVEHDHPHAL EFLRKDCTNV 360

NDFFLKHSVA VMTVRELFEF VTDPSITHEN MDAYLSKAME IASQRTKEER SSQDHVDEEV 420

FKRAYIPRTL NEVKHYERDM DLIMKLKEED MAVNAQQDNI LYQTVTGLKK DLSGVQKVPA 480

LLENQVEERT CSDSEDTGSS ECSDTDSEEQ GDHARPKKHT TGPDVDKKER KKMVKEAQRE 540

KRKNKIPKHV KKRKEKTAKT KKGK 564

Nucleotide Sequence
(FASTA)

ATGGACTACC GGCGTTTTCT TATGAGCCGG GTGGTCCCCG GGCAGTTCGA CGACGCGGAC 60

TCCTCTGACA GTGAAAACAG AAACTTGAAG ACAGTCAGAG AGAAGGATGA CATTCTGTTT 120

GAAAACCTTC AAGACAATGT GAATGAGAAT GGTGAAGGTG AAATAGAAGA TGAGGAGGAG 180

GACGGTTATG ATGATGATGA CGATTGGGAC TGGGATGAAG GAGTTGGAAA AGTCACTAAG 240

GGTTATGTCT GGAATGGAGG AAGCAACCCA CAGGCAAATC GACAGACCTC CGACAGCAGT 300

TCAGCCAAAA TGTCTACTCC AGCAGACAAG GTCTTACGGA AATTTGAGAA TAAAATTAAT 360

TTAGATAAGC TAAATGTTAC TGATTCTGTC ATAAATAAAG TCACCGAAAA GTCTAGACAA 420

AAGGAAGCAG ATATGTATCG CATCAAAGAT AAGGCAGACA GAGCAACTGT AGAACAGGTG 480

TTGGATCCCA GAACAAGAAT GATTTTATTC AAGATGTTGA CTAGAGGAAT CATAACAGAG 540

ATAAATGGCT GCATTAGCAC AGGAAAAGAA GCTAATGTAT ACCATGCTAG CACAGCAGAT 600

GGAGAGAGCA GAGCAATCAA AATTTATAAA ACTTCTATTT TGGTGTTCAA AGATCGGGAT 660

AAATATGTAA GTGGGGAATT CAGATTTCGT CATGGCTACT GTAAAGGAAA CCCTAGGAAA 720

ATGGTGAAAA CTTGGGCAGA AAAAGAAATG AGGAACTTAA TCAGGCTAAA CACAGCAGAG 780

ATACCGTGTC CAGAACCCAT AATGCTAAGA ATAGAGACGG GTTCATTTTC TTTTCATTCA 840

AGGCCTGCAC CACTCTTGAA AAATGTCCAG TTACCAGAAT CCAAGGCTCG GGAGTTGTAC 900

CTGCAGGTCA TTCAATACAT GAGAAGAATG TATCAGGATG CCAGACTCGT CCATGCAGAT 960

CTCAGTGAAT TTAACATGCT GTACCACGCT GGAGGCGTGT ATATCATTGA CGTTTCTCAG 1020

TCTGTGGAGC ACGACCACCC ACATGCCTTG GAGTTCTTGA GAAAGGATTG CACCAACGTC 1080

AATGATTTCT TTCTGAAGCA CAGTGTTGCC GTCATGACTG TGCGGGAGCT CTTTGAATTT 1140

GTCACAGATC CATCCATTAC ACATGAGAAC ATGGATGCTT ATCTCTCAAA GGCCATGGAA 1200

ATAGCATCTC AAAGGACCAA GGAGGAAAGG TCTAGCCAAG ATCATGTGGA TGAAGAGGTT 1260

TTTAAGCGAG CATATATTCC TAGAACCTTA AATGAAGTAA AACATTATGA GAGGGATATG 1320

GACCTAATTA TGAAATTGAA GGAAGAGGAC ATGGCCGTGA ATGCCCAACA AGATAATATT 1380

CTATACCAAA CTGTCACTGG ATTGAAGAAA GATTTGTCAG GAGTTCAGAA GGTCCCTGCA 1440

CTCCTAGAAA ATCAAGTGGA GGAAAGGACT TGTTCTGATT CAGAAGATAC TGGAAGCTCT 1500

GAGTGCTCTG ACACAGACTC TGAAGAGCAG GGAGACCATG CCCGCCCCAA GAAACACACC 1560

ACGGGCCCTG ACGTTGATAA AAAAGAAAGA AAAAAGATGG TCAAGGAAGC CCAGAGAGAG 1620

AAAAGAAAAA ACAAAATTCC TAAACATGTG AAAAAAAGAA AGGAGAAGAC AGCCAAGACG 1680

AAAAAAGGCA AATAG 1695

Domain Profile

S: 2     svgntigvgkesdvykvsekngeeraiKiyktsllvlknrdkYvdgefrfkksrskanpr  61

         +++++i++gke++vy++s+++ge+raiKiykts+lv+k+rdkYv+gefrf+++++k npr

Q: 180   EINGCISTGKEANVYHASTADGESRAIKIYKTSILVFKDRDKYVSGEFRFRHGYCKGNPR  239

         699*********************************************************

S: 62    klsrlwAeKEfrnlkrlyekgvpvPepidlkrhvlvmeligrdgypapklkdvklkeeei  121

         k++++wAeKE+rnl+rl+++++p+Pepi+l+ +    ++      pap lk+v+l e+++

Q: 240   KMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRIETGSFSFH---SRPAPLLKNVQLPESKA  296

         *********************************9999999...66***************

S: 122   kelYsdllalivklynegrLvHaDlsEfnilleddklvliDvsqsveieHpdaleflrrD  181

         +elY +++++++++y+++rLvHaDlsEfn+l++++++++iDvsqsve++Hp+aleflr+D

Q: 297   RELYLQVIQYMRRMYQDARLVHADLSEFNMLYHAGGVYIIDVSQSVEHDHPHALEFLRKD  356

         ************************************************************

S: 182   vknvkefFkkklvydvlrerelfelvsasgltkekead  219

         ++nv++fF k++v +v+++relfe+v++ ++t+e+++

Q: 357   CTNVNDFFLKHSV-AVMTVRELFEFVTDPSITHENMDA  393

         *************.*********************985

Domain Sequence
(FASTA)

EINGCISTGK EANVYHASTA DGESRAIKIY KTSILVFKDR DKYVSGEFRF RHGYCKGNPR 60

KMVKTWAEKE MRNLIRLNTA EIPCPEPIML RIETGSFSFH SRPAPLLKNV QLPESKAREL 120

YLQVIQYMRR MYQDARLVHA DLSEFNMLYH AGGVYIIDVS QSVEHDHPHA LEFLRKDCTN 180

VNDFFLKHSV AVMTVRELFE FVTDPSITHE NMDA 214

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>