EKS-MAM-00335

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00335

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	302.0	6.2E-90	11	321	311

Status

Unreviewed

Ensembl Protein

ENSMMUP00000034229

UniProt Accession

F7AI65;

Protein Name

Protein Synonyms/Alias

STE20-related kinase adapter protein alpha isoform 1;

Gene Name

STRADA

Gene Synonyms/Alias

STRADA; EGK_08864;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000016757	ENSMMUP00000022029	ENSMMUT00000023546
ENSMMUG00000016757	ENSMMUP00000022028	ENSMMUT00000023545
ENSMMUG00000016757	ENSMMUP00000034229	ENSMMUT00000041193
ENSMMUG00000016757	ENSMMUP00000022030	ENSMMUT00000023547

Organism

Macaca mulatta

Functional Description

Protein Length

373

Protein Sequence
(FASTA)

MSSFLPEGGC YELLTVIGKG FEDLMTVNLA RYKPTGEYVT VRRINLEACS NEMVTFLQGE 60

LHVSKLFNHP NIVPYRATFI ADNELWVVTS FMAYGSAKDL ICTHFMDGMN ELAIAYILQG 120

VLKALDYIHH MGYVHRSVKA SHILISLDGK VYLSGLRSNL SMISHGQRQR VVHDFPKYSV 180

KVLPWLSPEV LQQNLQGYDA KSDIYSVGIT ACELANGHVP FKDMPATQML LEKLNGTVPC 240

LLDTSTIPAE ELTMSPSRSV ANSGLSDSLT TSTPRPSNGD SPSHPYHRTF SPYFHHFVEQ 300

CLQRNPDARP SASTLLNHSF FKQIKRRASE ALPELLRPVT PITNFESSQS QDHSGIFGLV 360

TNLEELEVDD WEF 373

Nucleotide Sequence
(FASTA)

ATGAGTAGCT TTCTGCCAGA GGGAGGGTGT TACGAGCTGC TCACTGTGAT AGGCAAAGGA 60

TTTGAGGACC TGATGACTGT GAATCTAGCG AGGTACAAAC CAACGGGAGA GTATGTGACT 120

GTACGGAGGA TTAACCTAGA AGCTTGTTCC AATGAGATGG TAACATTCTT GCAGGGTGAG 180

CTGCATGTCT CCAAACTCTT CAACCATCCT AATATTGTGC CATATCGAGC CACTTTTATT 240

GCAGACAATG AGCTGTGGGT TGTCACATCA TTCATGGCAT ATGGTTCTGC AAAGGATCTC 300

ATCTGTACAC ACTTCATGGA TGGCATGAAT GAGCTGGCGA TCGCTTACAT TCTGCAGGGG 360

GTCCTGAAGG CCCTCGACTA CATCCACCAC ATGGGCTATG TACACAGGAG TGTCAAAGCC 420

AGCCACATCC TGATCTCTCT GGATGGGAAG GTCTACCTGT CTGGTTTGCG CAGCAACCTC 480

AGCATGATAA GCCATGGGCA GCGGCAGCGA GTGGTCCACG ATTTTCCAAA GTACAGTGTC 540

AAGGTTCTGC CGTGGCTCAG CCCCGAGGTC CTCCAGCAGA ATCTCCAGGG TTATGATGCC 600

AAATCTGACA TCTACAGTGT GGGAATCACA GCCTGTGAAC TGGCAAACGG CCACGTCCCC 660

TTTAAGGATA TGCCTGCCAC CCAGATGCTG CTAGAGAAAC TAAACGGCAC AGTGCCCTGC 720

CTGTTGGATA CCAGCACCAT CCCTGCCGAG GAGCTGACCA TGAGCCCTTC GCGCTCAGTG 780

GCCAACTCTG GCCTGAGTGA CAGCCTGACC ACCAGCACCC CACGGCCCTC CAATGGCGAC 840

TCGCCTTCCC ACCCCTACCA CCGAACCTTC TCCCCCTACT TCCACCACTT TGTGGAGCAG 900

TGCCTTCAGC GCAACCCGGA TGCCAGGCCC AGTGCCAGCA CCCTCCTGAA CCACTCTTTC 960

TTCAAGCAGA TCAAGCGACG TGCCTCAGAG GCTTTGCCTG AATTGCTTCG TCCTGTCACC 1020

CCCATCACCA ATTTTGAGAG CAGCCAGTCT CAGGACCATA GTGGAATCTT TGGCCTGGTA 1080

ACAAACCTGG AAGAGCTGGA GGTGGATGAT TGGGAGTTCT GA 1122

Domain Profile

S: 1     yelleeigkG..algkvylarekktgelvaikkinlekq..ekleelqkeisvlkklkhp  56

         yell++igkG  +l++v+lar k+tge+v++++inle++  e+++ lq e++v+k ++hp

Q: 11    YELLTVIGKGfeDLMTVNLARYKPTGEYVTVRRINLEACsnEMVTFLQGELHVSKLFNHP  70

         99********999**************************9999*****************

S: 57    niveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHs  116

         niv y ++f++++elw+v++++a+Gs++dl+ ++++++++E +iayil++vlkaL+y+H+

Q: 71    NIVPYRATFIADNELWVVTSFMAYGSAKDLICTHFMDGMNELAIAYILQGVLKALDYIHH  130

         ************************************************************

S: 117   kkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtp.......ywmAPEv  169

         ++++Hr++ka++iL++ +g+V+Ls+++++ ++ ++++++++v+++p       +w++PEv

Q: 131   MGYVHRSVKASHILISLDGKVYLSGLRSNLSMISHGQRQRVVHDFPkysvkvlPWLSPEV  190

         **********************************************99988888******

S: 170   iaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilkneppklksk......  223

         ++q+ +gYd+k+Di+s+GIta+ela+g++Pfkd++++++ll++l++++p l ++

Q: 191   LQQNLQGYDAKSDIYSVGITACELANGHVPFKDMPATQMLLEKLNGTVPCLLDTstipae  250

         *************************************************88666677888

S: 224   .....................................kkfskefkefvekclqknpekRp  246

                                              ++fs+ f++fve+clq+np++Rp

Q: 251   eltmspsrsvansglsdslttstprpsngdspshpyhRTFSPYFHHFVEQCLQRNPDARP  310

         888889999999999999999999999999999999999*********************

S: 247   sasellkhkFl  257

         sas+ll+h+F+

Q: 311   SASTLLNHSFF  321

         **********7

Domain Sequence
(FASTA)

YELLTVIGKG FEDLMTVNLA RYKPTGEYVT VRRINLEACS NEMVTFLQGE LHVSKLFNHP 60

NIVPYRATFI ADNELWVVTS FMAYGSAKDL ICTHFMDGMN ELAIAYILQG VLKALDYIHH 120

MGYVHRSVKA SHILISLDGK VYLSGLRSNL SMISHGQRQR VVHDFPKYSV KVLPWLSPEV 180

LQQNLQGYDA KSDIYSVGIT ACELANGHVP FKDMPATQML LEKLNGTVPC LLDTSTIPAE 240

ELTMSPSRSV ANSGLSDSLT TSTPRPSNGD SPSHPYHRTF SPYFHHFVEQ CLQRNPDARP 300

SASTLLNHSF F 311

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0030295	; F:protein kinase activator activity
GO:0004672	; F:protein kinase activity
GO:0032147	; P:activation of protein kinase activity
GO:0006611	; P:protein export from nucleus

KEGG

mcc:717927

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013