EKS-MAM-00390

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00390

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE11	345.0	6.1E-103	243	506	264

Status

Unreviewed

Ensembl Protein

ENSMMUP00000022526

UniProt Accession

F7HFC2;

Protein Name

Protein Synonyms/Alias

Gene Name

YSK4

Gene Synonyms/Alias

YSK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000017121	ENSMMUP00000036061	ENSMMUT00000043047
ENSMMUG00000017121	ENSMMUP00000036060	ENSMMUT00000043046
ENSMMUG00000017121	ENSMMUP00000022526	ENSMMUT00000024071

Organism

Macaca mulatta

Functional Description

Protein Length

510

Protein Sequence
(FASTA)

MSSMPKPERH AESLLDICHD TSSSPTDMMI VTKNQNIILQ SISSSEEFDQ DGDCSHSTPV 60

SEEEDPSGGR QDWQPRTEGI EITVTFPRDV SPPQEMSQED LKERNQITSS HQEWAQAHAV 120

SHPNEIEMVE LRTNTLTMRP LLLQKEESSR ELCDVNLGFL LPRSCLEPNI SKSVTREDAP 180

HFLKEQQRKS EESSTSDVKY SGQSIERHSN GLRTYDREEK FLISNEKMTF SENSLKSEEP 240

ILWTKGEILG KGAYGTVYCG LTSQGQLIAV KQVALDTSDK LATEKEYQKL QEEVDLLKAL 300

KHVNIVAYLG TCLQENTVSI FMEFVPGGSI SSIINRFGPL PEMVFCKYTK QILQGVAYLH 360

ENCVVHRDIK GNNVMLMPTG IIKLIDFGCA KRLAWAGLNG THSDMLKSMH GTPYWMAPEV 420

INESGYGRKS DIWSIGCTVF EMATGKPPLA SMDRMAAMFY IGAHRGLMPP LPDHFSENAA 480

DFVRMCLTRD QHERPSALQL LKHSFLERSH 510

Nucleotide Sequence
(FASTA)

ATGAGTTCTA TGCCAAAACC AGAAAGACAT GCTGAGTCAT TGCTTGACAT TTGTCATGAT 60

ACAAGCTCTT CTCCAACTGA TATGATGATA GTTACCAAAA ATCAAAACAT CATCTTGCAA 120

AGCATCAGCA GCAGTGAGGA GTTCGACCAA GATGGTGACT GCAGTCATTC CACACCGGTT 180

AGTGAAGAAG AAGATCCCAG TGGTGGTAGA CAGGACTGGC AACCCAGGAC AGAAGGTATT 240

GAGATCACTG TGACTTTTCC AAGAGATGTC AGTCCTCCCC AAGAAATGAG CCAAGAAGAC 300

TTAAAAGAAA GGAATCAGAT AACCTCATCG CATCAAGAAT GGGCACAAGC ACATGCAGTT 360

TCTCATCCAA ATGAAATTGA GATGGTGGAG CTCAGGACAA ACACGCTGAC CATGCGGCCC 420

TTACTTTTGC AAAAAGAGGA AAGTTCCAGG GAGCTCTGCG ATGTGAACTT GGGCTTTTTG 480

CTGCCGAGAT CTTGTTTAGA ACCAAACATT TCCAAGTCTG TAACCAGAGA AGATGCTCCT 540

CATTTTCTGA AGGAGCAGCA AAGAAAATCT GAAGAATCTT CGACCTCTGA TGTGAAGTAC 600

AGTGGCCAAA GCATCGAGAG GCATAGTAAT GGGCTCAGGA CATATGACAG GGAGGAGAAA 660

TTTCTCATCT CAAATGAAAA GATGACATTT TCTGAAAATA GTTTAAAGTC TGAAGAACCT 720

ATCCTATGGA CCAAGGGTGA GATTCTTGGA AAGGGAGCCT ATGGCACAGT ATACTGTGGT 780

CTCACTAGCC AAGGGCAGCT AATAGCTGTA AAACAGGTGG CTTTGGATAC CTCTGATAAA 840

TTAGCTACTG AAAAGGAATA CCAGAAACTA CAGGAAGAAG TAGATTTGCT CAAAGCACTG 900

AAACATGTCA ACATTGTGGC CTATTTGGGG ACATGCTTGC AAGAGAACAC TGTGAGCATT 960

TTCATGGAGT TTGTCCCTGG TGGCTCAATC TCTAGTATTA TAAACCGTTT TGGGCCATTG 1020

CCTGAGATGG TGTTCTGTAA ATATACGAAA CAAATTCTGC AAGGTGTTGC TTATCTCCAT 1080

GAGAACTGTG TAGTACATCG CGATATAAAA GGAAATAATG TTATGCTCAT GCCAACTGGA 1140

ATAATAAAGC TGATTGACTT TGGCTGTGCC AAGCGTTTGG CCTGGGCAGG TTTAAATGGC 1200

ACCCACAGTG ACATGCTTAA GTCCATGCAT GGGACTCCAT ATTGGATGGC CCCAGAAGTC 1260

ATCAATGAGT CTGGCTATGG AAGGAAATCA GATATCTGGA GCATCGGTTG TACTGTGTTT 1320

GAGATGGCTA CAGGGAAGCC TCCACTGGCT TCCATGGACA GGATGGCTGC CATGTTTTAC 1380

ATCGGAGCAC ACCGAGGGCT GATGCCTCCT TTACCAGACC ACTTCTCAGA AAATGCAGCA 1440

GACTTTGTGC GCATGTGCCT GACCAGGGAC CAGCATGAGC GACCTTCTGC TCTCCAGCTC 1500

CTGAAGCACT CCTTCTTGGA GAGAAGTCAC TGA 1533

Domain Profile

S: 1     wqkrevigkGsfgsvyaaldvdtgellavKeveikp.ekksekkevkalkeEikllkelk  59

         w+k+e++gkG++g+vy++l+ ++g+l+avK+v++++ +k +++ke+++l+eE++llk+lk

Q: 243   WTKGEILGKGAYGTVYCGLT-SQGQLIAVKQVALDTsDKLATEKEYQKLQEEVDLLKALK  301

         89*****************8.89***********8614556778****************

S: 60    HenivkyyGveveeeelkiflEyvegGslssllekygkleesvikkytkqileglayLHe  119

         H niv y+G++ +e++++if+E+v+gGs+ss+++++g+l e+v++kytkqil+g+ayLHe

Q: 302   HVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGPLPEMVFCKYTKQILQGVAYLHE  361

         ************************************************************

S: 120   kkivHRDiKgaNilldssgvvklsDFGaskrlaelntkaae...lesltGtlaymaPEvi  176

         +++vHRDiKg+N++l+ +g++kl DFG++krla++  + ++   l+s++Gt+++maPEvi

Q: 362   NCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRLAWAGLNGTHsdmLKSMHGTPYWMAPEVI  421

         **********************************999988877899**************

S: 177   kkkekgygrkaDiWslgcvviemltgkrPfaeldeelaimfkvgakk.tkPeipeklsee  235

         +++  gygrk+DiWs+gc+v+em+tgk+P a++ +++a+mf +ga++  +P++p+++se+

Q: 422   NES--GYGRKSDIWSIGCTVFEMATGKPPLASM-DRMAAMFYIGAHRgLMPPLPDHFSEN  478

         988..****************************.9**********9979***********

S: 236   gkdflekcleldpkkrpsaeeLLkhefl  263

         + df++ cl++d+++rpsa +LLkh+fl

Q: 479   AADFVRMCLTRDQHERPSALQLLKHSFL  506

         **************************96

Domain Sequence
(FASTA)

WTKGEILGKG AYGTVYCGLT SQGQLIAVKQ VALDTSDKLA TEKEYQKLQE EVDLLKALKH 60

VNIVAYLGTC LQENTVSIFM EFVPGGSISS IINRFGPLPE MVFCKYTKQI LQGVAYLHEN 120

CVVHRDIKGN NVMLMPTGII KLIDFGCAKR LAWAGLNGTH SDMLKSMHGT PYWMAPEVIN 180

ESGYGRKSDI WSIGCTVFEM ATGKPPLASM DRMAAMFYIG AHRGLMPPLP DHFSENAADF 240

VRMCLTRDQH ERPSALQLLK HSFL 264

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

mcc:712728

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013