EKS-MAM-00338

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00338

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE20	283.1	3.8E-84	57	368	312

Status

Unreviewed

Ensembl Protein

ENSMMUP00000023212

UniProt Accession

F7F789;

Protein Name

Protein Synonyms/Alias

STE20-related kinase adapter protein beta isoform 1;

Gene Name

STRADB

Gene Synonyms/Alias

STRADB;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000018141	ENSMMUP00000023852	ENSMMUT00000025494
ENSMMUG00000018141	ENSMMUP00000023212	ENSMMUT00000024802

Organism

Macaca mulatta

Functional Description

Protein Length

376

Protein Sequence
(FASTA)

NFQDCFCTSR TQVESLRPEK QSETSIHQYL VDEPTLSWSP PSTRASEVVC STNVSHYELQ 60

VEIGRGFDNL TSVHLARHTP TGTLVTIKIT NLENCNEERL KALQKAVILS HFFRHPNITT 120

YWTVFTVGSW LWVISPFMAY GSASQLLRTY FPEGMSETLI RNILFGAVRG LNYLHQNGYI 180

HRSIKASHIL ISGDGLVTLS GLSHLHSLVK HGQRHTAVYD FPQFSTSVQP WLSPELLRQD 240

LHGYNVKSDI YSVGITACEL ASGQVPFQDM HRTQMLLQKL KGPPYSPLDI SIFPQSESRM 300

KNSRSGVDSG IGESVLVSSG THTVNSDRLH TPSSKTFSPA FFSLVQLCLQ QDPEKRPSAS 360

SLLSHVFFKQ PYFEFL 376

Nucleotide Sequence
(FASTA)

AACTTCCAGG ATTGTTTCTG CACTTCAAGA ACACAAGTTG AATCACTCAG ACCTGAAAAA 60

CAGTCTGAAA CCAGTATCCA TCAATACTTG GTTGATGAGC CAACCCTTTC CTGGTCACCT 120

CCATCCACTA GAGCAAGCGA AGTAGTATGT TCCACCAACG TTTCTCACTA CGAGCTCCAA 180

GTAGAAATAG GAAGAGGATT TGACAACTTG ACTTCTGTCC ATCTTGCACG GCATACTCCC 240

ACGGGAACAC TGGTAACTAT AAAAATTACA AATCTGGAAA ACTGCAATGA AGAACGCCTG 300

AAAGCTTTAC AGAAAGCCGT GATTCTCTCC CACTTTTTCC GGCATCCCAA TATTACAACT 360

TATTGGACAG TTTTCACTGT TGGCAGCTGG CTTTGGGTTA TTTCTCCATT TATGGCCTAT 420

GGTTCAGCAA GTCAACTCTT GAGGACCTAT TTTCCTGAGG GAATGAGTGA AACTTTAATA 480

AGAAACATTC TCTTTGGAGC AGTGAGAGGG TTGAACTATC TGCACCAAAA TGGCTATATT 540

CACAGGAGTA TTAAAGCCAG CCATATCCTC ATTTCTGGTG ATGGCCTAGT GACCCTCTCT 600

GGCCTGTCCC ATCTGCATAG TTTGGTTAAG CATGGACAGA GGCATACGGC TGTGTATGAT 660

TTCCCACAGT TCAGCACATC AGTGCAGCCG TGGCTGAGTC CAGAACTACT GAGACAGGAT 720

TTACATGGGT ATAATGTGAA GTCAGATATT TACAGTGTTG GGATTACAGC ATGTGAATTA 780

GCCAGTGGGC AGGTGCCTTT CCAGGACATG CATAGAACTC AGATGCTGTT ACAGAAACTG 840

AAAGGTCCTC CTTACAGCCC ATTGGATATC AGTATTTTCC CTCAATCAGA ATCCAGAATG 900

AAAAACTCCC GGTCAGGTGT AGACTCTGGG ATTGGAGAAA GCGTGCTTGT CTCCAGTGGA 960

ACTCACACAG TAAATAGTGA CCGATTACAC ACACCATCCT CAAAAACCTT CTCTCCTGCC 1020

TTCTTTAGCT TGGTACAGCT CTGTTTGCAA CAAGATCCTG AGAAAAGGCC ATCAGCAAGC 1080

AGTTTATTGT CCCATGTTTT CTTCAAACAG CCTTATTTTG AGTTTCTTTA A 1131

Domain Profile

S: 1     yelleeigkG..algkvylarekktgelvaikkinlekq..ekleelqkeisvlkklkhp  56

         yel+ eig+G  +l++v+lar+++tg+lv+ik++nle++  e+l++lqk + +++ ++hp

Q: 57    YELQVEIGRGfdNLTSVHLARHTPTGTLVTIKITNLENCneERLKALQKAVILSHFFRHP  116

         899********99**************************9999*****************

S: 57    niveylesflkeeelwlvmeylagGslsdlvkeelkselkEeqiayilrevlkaLeylHs  116

         ni++y+++f++ ++lw++  ++a+Gs+s+l+++++ ++++E+ i++il +++++L+ylH+

Q: 117   NITTYWTVFTVGSWLWVISPFMAYGSASQLLRTYFPEGMSETLIRNILFGAVRGLNYLHQ  176

         ************************************************************

S: 117   kkviHrdikakniLlteegeVkLsdfgvaaqlektrkkrktvvgtp.......ywmAPEv  169

         +++iHr+ika++iL++ +g V+Ls++++ ++l k+++++++v+++p       +w++PE+

Q: 177   NGYIHRSIKASHILISGDGLVTLSGLSHLHSLVKHGQRHTAVYDFPqfstsvqPWLSPEL  236

         **********************************************99999888******

S: 170   iaqeekgYdekaDiwslGItaielaegepPfkdleplkallkilknepp...........  218

         ++q+ +gY+ k+Di+s+GIta+ela+g++Pf+d++++++ll++lk++p

Q: 237   LRQDLHGYNVKSDIYSVGITACELASGQVPFQDMHRTQMLLQKLKGPPYspldisifpqs  296

         **********************************************94433666666655

S: 219   ..klksk..................................kkfskefkefvekclqknp  242

           +                                      k+fs++f ++v+ clq++p

Q: 297   esR---MknsrsgvdsgigesvlvssgthtvnsdrlhtpssKTFSPAFFSLVQLCLQQDP  353

         553...0445888888999999999999999999999999899*****************

S: 243   ekRpsasellkhkFl  257

         ekRpsas+ll+h F+

Q: 354   EKRPSASSLLSHVFF  368

         *************97

Domain Sequence
(FASTA)

YELQVEIGRG FDNLTSVHLA RHTPTGTLVT IKITNLENCN EERLKALQKA VILSHFFRHP 60

NITTYWTVFT VGSWLWVISP FMAYGSASQL LRTYFPEGMS ETLIRNILFG AVRGLNYLHQ 120

NGYIHRSIKA SHILISGDGL VTLSGLSHLH SLVKHGQRHT AVYDFPQFST SVQPWLSPEL 180

LRQDLHGYNV KSDIYSVGIT ACELASGQVP FQDMHRTQML LQKLKGPPYS PLDISIFPQS 240

ESRMKNSRSG VDSGIGESVL VSSGTHTVNS DRLHTPSSKT FSPAFFSLVQ LCLQQDPEKR 300

PSASSLLSHV FF 312

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0032147	; P:activation of protein kinase activity
GO:0000902	; P:cell morphogenesis
GO:0007254	; P:JNK cascade
GO:0006611	; P:protein export from nucleus

KEGG

mcc:641449

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013