| Tag | Content |
|---|
| EKPD ID | EPS-MAM-00009 |
| Classification | | Group/Family | Score | E-Value | Start | End | Domain Length |
|---|
| DSP/aDSP | 147.3 | 5.1E-43 | 5 | 141 | 137 |
|
| Status | Unreviewed |
| Ensembl Protein | ENSMMUP00000024359 |
| UniProt Accession | F7A8S7; |
| Protein Name | |
| Protein Synonyms/Alias | Dual specificity protein phosphatase 22; |
| Gene Name | DUSP22 |
| Gene Synonyms/Alias | DUSP22; |
| Ensembl Information | |
| Organism | Macaca mulatta |
| Functional Description | |
| Protein Length | 184 |
Protein Sequence
(FASTA) | | MGNGMNKILP GLYIGNFKDA RDAEQLSKNK VTHILSVHDS ARPMLEGVKY LCIPAADSPS 60 | | QNLTRHFKES IKFIHECRLR GESCLVHCLA GVSRSVTLVI AYIMTVTDFG WEDALHTVRA 120 | | GRSCANPNVG FQRQLQEFEK HEVHQYRQWL REEYGESPLQ DAEEAKSILA APGILKYWAF 180 | | LRRL 184 |
|
Nucleotide Sequence
(FASTA) | | ATGGGGAATG GGATGAACAA GATCCTGCCC GGCCTGTACA TCGGCAACTT CAAAGATGCC 60 | | AGGGATGCGG AACAGTTGAG CAAGAACAAG GTGACACATA TTCTGTCTGT CCACGACAGT 120 | | GCCCGGCCTA TGCTGGAGGG AGTTAAATAC CTGTGCATCC CAGCAGCGGA TTCACCGTCT 180 | | CAAAACCTGA CAAGACATTT CAAAGAAAGT ATTAAATTCA TTCATGAGTG CCGGCTGCGC 240 | | GGTGAGAGCT GCCTCGTACA CTGCCTGGCC GGGGTCTCCA GGAGCGTGAC GCTGGTGATC 300 | | GCGTACATCA TGACCGTCAC CGACTTTGGC TGGGAGGACG CCCTGCACAC CGTGCGTGCT 360 | | GGGAGATCCT GTGCCAACCC CAACGTGGGC TTCCAGAGAC AGCTCCAGGA GTTTGAGAAG 420 | | CATGAGGTCC ATCAGTATCG GCAGTGGCTG AGGGAAGAGT ACGGGGAGAG CCCTTTGCAG 480 | | GACGCAGAAG AAGCCAAAAG CATTCTCGCC GCTCCGGGAA TTCTGAAGTA CTGGGCCTTT 540 | | CTCAGAAGAC TGTAA 555 |
|
| Domain Profile | S: 2 vteilpglylgdqataldrreLsklgitvvinaslsvikvqviPeylikkgityknipvd 61 | +++ilpgly+g+ ++a d +Lsk+++t+++ + s + +g++y+ ip+ | Q: 5 MNKILPGLYIGNFKDARDAEQLSKNKVTHILSVHDSARP--------MLEGVKYLCIPAA 56 | 689*************************99987666554........569********** |
| S: 62 DsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAie 121 | Ds++++l ++f+e ++fi+e++ +g+++lvHC aGvsRS+tlv+aY+m+v+++ ++dA++ | Q: 57 DSPSQNLTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALH 116 | ************************************************************ |
| S: 122 avkrkrpsiepnegfleQLlelekk 146 | +v++ r++++pn gf +QL e+ek+ | Q: 117 TVRAGRSCANPNVGFQRQLQEFEKH 141 | ***********************96 |
|
Domain Sequence
(FASTA) | | MNKILPGLYI GNFKDARDAE QLSKNKVTHI LSVHDSARPM LEGVKYLCIP AADSPSQNLT 60 | | RHFKESIKFI HECRLRGESC LVHCLAGVSR SVTLVIAYIM TVTDFGWEDA LHTVRAGRSC 120 | | ANPNVGFQRQ LQEFEKH 137 |
|
| Keyword | Complete proteome; Reference proteome. |
| Sequence Source | Ensembl |
| Orthology | |
| Gene Ontology | | GO:0008138 | ; F:protein tyrosine/serine/threonine phosphatase activity | | GO:0000122 | ; P:negative regulation of transcription from RNA polymerase II promoter | | GO:0046330 | ; P:positive regulation of JNK cascade | | GO:0006470 | ; P:protein dephosphorylation | | GO:0042127 | ; P:regulation of cell proliferation | | GO:0007179 | ; P:transforming growth factor beta receptor signaling pathway |
|
| KEGG | |
| InterPros | |
| Pfam | |
| SMARTs | |
| Prosites | |
| Prints | |
| Created Date | 20-Feb-2013 |