EKS-MAM-00094

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00094

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	396.8	1.5E-118	2153	2477	325

Status

Unreviewed

Ensembl Protein

ENSMMUP00000025391

UniProt Accession

F6RVV5;

Protein Name

Protein Synonyms/Alias

Gene Name

MTOR

Gene Synonyms/Alias

MTOR;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000019325	ENSMMUP00000025391	ENSMMUT00000027142

Organism

Macaca mulatta

Functional Description

Protein Length

2549

Protein Sequence
(FASTA)

MLGTGPAAAT TAATTSSNVS VLQQFASGLK SRNEETRAKA AKELQHYVTM ELREMSQEES 60

TRFYDQLNHH IFELVSSSDA NERKGGILAI ASLIGVEGGN ATRIGRFANY LRNLLPSNDP 120

VVMEMASKAI GRLAMAGDTF TAEYVEFESE QAFSVPSVTK HWYRREFSVL VLRELAISVP 180

TFFFQQVQPF FDNIFVAVWD PKQAIREGAV AALRACLILT TQREPKEMQK PQWYRHTFEE 240

AEKGFDETLA KEKGMNRDDR IHGALLILNE LVRISSMEGE RLREEMEEIT QQQLVHDKYC 300

KDLMGFGTKP RHITPFTSFQ AVQPQQSNAL VGLLGYSSHQ GLMGFGASPS PAKSTLVESR 360

CCRDLMEEKF DQVCQWVLKC RNSKNSLIQM TILNLLPRLA AFRPSAFTDT QYLQDTMNHV 420

LSCVKKEKER TAAFQALGLL SVAVRSEFKV YLPRVLDIIR AALPPKDFAH KRQKAMQVDA 480

TVFTCISMLA RAMGPSIQQD IKELLEPMLA VGLSPALTAV LYDLSRQIPQ LKKDIQDGLL 540

KMLSLVLMHK PLRHPGMPKG LAHQLASPGL TTLPEASDVG SITLALRTLG SFEFEGHSLT 600

QFVRHCADHF LNSEHKEIRM EAARTCSRLL TPSIHLISGH AHVVSQTAVQ VVADVLSKLL 660

VVGITDPDPD IRYCVLASLD ERFDAHLAQA ENLQALFVAL NDQVFEIREL AICTVGRLSS 720

MNPAFVMPFL RKMLIQILTE LEHSGIGRIK EQSARMLGHL VSNAPRLIRP YMEPILKALI 780

LKLKDPDPDP NPGVINNVLA TIGELAQVSG LEMRKWVDEL FIIIMDMLQD SSLLAKRQVA 840

LWTLGQLVAS TGYVVEPYRK YPTLLEVLLN FLKTEQNQGT RREAIRVLGL LGALDPYKHK 900

VNIGMIDQSR DASAVSLSES KSSQDSSDYS TSEMLVNMGN LPLDEFYPAV SMVALMRIFR 960

DQSLSHHHTM VVQAITFIFK SLGLKCVQFL PQVMPTFLNV IRVCDGAIRE FLFQQLGMLV 1020

SFVKSHIRPY MDEIVTLMRE FWVMNTSIQS TIILLIEQIV VALGGEFKLY LPQLIPHMLR 1080

VFMHDNSPGR IVSIKLLAAI QLFGANLDDY LHLLLPPIVK LFDAPEAPLP SRKAALETVD 1140

RLTESLDFTD YASRIIHPIV RTLDQSPELR STAMDTLSSL VFQLGKKYQI FIPMVNKVLV 1200

RHRINHQRYD VLICRIVKGY TLADEEEDPL IYQHRMLRSG QGDALASGPV ETGPMKKLHV 1260

STINLQKAWG AARRVSKDDW LEWLRRLSLE LLKDSSSPSL RSCWALAQAY NPMARDLFNA 1320

AFVSCWSELN EDQQDELIRS IELALTSQDI AEVTQTLLNL AEFMEHSDKG PLPLRDDNGI 1380

VLLGERAAKC RAYAKALHYK ELEFQKGPTP AILESLISIN NKLQQPEAAA GVLEYAMKHF 1440

GELEIQATWY EKLHEWEDAL VAYDKKMDTN KDDPELMLGR MRCLEALGEW GQLHQQCCEK 1500

WTLVNDETQA KMARMAAAAA WGLGQWDSME EYTCMIPRDT HDGAFYRAVL ALHQDLFSLA 1560

QQCIDKARDL LDAELTAMAG ESYSRAYGAM VSCHMLSELE EVIQYKLVPE RREIIRQIWW 1620

ERLQGCQRIV EDWQKILMVR SLVVSPHEDM RTWLKYASLC GKSGRLALAH KTLVLLLGVD 1680

PSRQLDHPLP TVHPQVTYAY MKNMWKSARK IDAFQHMQHF VQTMQQQAQH AIATEDQQHK 1740

QELHKLMARC FLKLGEWQLN LQGINESTIP KVLQYYSAAT EHDRSWYKAW HAWAVMNFEA 1800

VLHYKHQNQA RDEKKKLRHA SGANITNTTT AATTAATATT TASTEGSNSE SEAESTENSP 1860

TPSPLQKKVT EDLSKTLLMY TVPAVQGFFR SISLSRGNNL QDTLRVLTLW FDYGHWPDVN 1920

EALVEGVKAI QIDTWLQVIP QLIARIDTPR PLVGRLIHQL LTDIGRYHPQ ALIYPLTVAS 1980

KSTTTARHNA ANKILKNMCE HSNTLVQQAM MVSEELIRVA ILWHEMWHEG LEEASRLYFG 2040

ERNVKGMFEV LEPLHAMMER GPQTLKETSF NQAYGRDLME AQEWCRKYMK SGNVKDLTQA 2100

WDLYYHVFRR ISKQLPQLTS LELQYVSPKL LMCRDLELAV PGTYDPNQPI IRIQSIAPSL 2160

QVITSKQRPR KLTLMGSNGH EFVFLLKGHE DLRQDERVMQ LFGLVNTLLA NDPTSLRKNL 2220

SIQRYAVIPL STNSGLIGWV PHCDTLHALI RDYREKKKIL LNIEHRIMLR MAPDYDHLTL 2280

MQKVEVFEHA VNNTAGDDLA KLLWLKSPSS EVWFDRRTNY TRSLAVMSMV GYILGLGDSF 2340

PKWFHLSQLF GKLRKATCST WLQVAMTREK FPEKIPFRLT RMLTNAMEVT GLDGNYRITC 2400

HTVMEVLREH KDSVMAVLEA FVYDPLLNWR LMDTNTKGNK RSRTRTDSYS AGQSVEILDG 2460

VELGEPAHKK TGTTVPESIH SFIGDGLVKP EALNKKAIQI INRVRDKLTG RDFSHDDTLD 2520

VPTQVELLIK QATSHENLCQ CYIGWCPFW 2549

Nucleotide Sequence
(FASTA)

ATGCTTGGAA CCGGACCTGC CGCCGCCACC ACCGCTGCCA CCACATCTAG CAATGTGAGT 60

GTTCTACAGC AGTTTGCCAG TGGCCTGAAG AGCCGGAATG AAGAGACCAG GGCCAAAGCT 120

GCCAAGGAGC TCCAGCACTA TGTCACCATG GAACTCCGAG AGATGAGTCA AGAGGAGTCT 180

ACTCGCTTCT ATGACCAGCT GAACCATCAC ATTTTTGAAT TGGTTTCCAG CTCAGATGCC 240

AATGAGAGGA AAGGTGGCAT CTTGGCCATA GCCAGCCTCA TAGGAGTGGA AGGTGGGAAT 300

GCCACCCGAA TTGGCAGATT TGCCAACTAT CTTCGGAACC TCCTCCCCTC CAATGACCCA 360

GTTGTCATGG AAATGGCATC CAAGGCCATC GGCCGCCTTG CCATGGCAGG AGACACTTTC 420

ACCGCTGAGT ATGTGGAATT TGAGAGTGAG CAAGCCTTCT CTGTTCCTAG TGTAACAAAG 480

CACTGGTACC GACGAGAGTT CTCGGTCCTG GTTCTCCGTG AGCTGGCCAT CAGCGTCCCT 540

ACCTTCTTCT TCCAGCAAGT GCAGCCCTTC TTTGACAACA TTTTTGTGGC CGTGTGGGAC 600

CCCAAACAAG CCATCCGTGA GGGAGCTGTG GCCGCCCTTC GTGCCTGTTT GATTCTCACC 660

ACCCAGCGTG AGCCGAAGGA GATGCAGAAG CCTCAGTGGT ACAGGCACAC ATTTGAAGAA 720

GCAGAGAAAG GGTTTGATGA GACCTTGGCC AAAGAGAAGG GCATGAATCG GGATGATCGG 780

ATCCATGGAG CCTTGCTGAT CCTTAACGAG CTGGTCCGAA TCAGCAGCAT GGAGGGAGAG 840

CGTCTGAGAG AAGAAATGGA AGAAATCACA CAGCAGCAGC TGGTACATGA CAAGTACTGC 900

AAAGACCTCA TGGGCTTCGG AACAAAACCT CGTCACATTA CCCCCTTCAC CAGCTTCCAG 960

GCTGTACAGC CCCAGCAGTC AAATGCCTTG GTGGGGCTGC TGGGGTACAG CTCTCACCAA 1020

GGCCTCATGG GATTTGGGGC CTCCCCCAGC CCAGCTAAGT CCACCCTGGT GGAGAGCCGG 1080

TGTTGCAGAG ACTTGATGGA GGAGAAATTT GATCAGGTAT GCCAGTGGGT GCTGAAATGC 1140

AGGAATAGCA AGAACTCGCT GATCCAAATG ACAATCCTTA ATTTGTTGCC CCGCTTGGCT 1200

GCATTCCGAC CTTCTGCCTT CACAGATACT CAGTACCTCC AAGATACTAT GAACCATGTC 1260

CTAAGCTGTG TCAAGAAGGA GAAGGAACGT ACAGCAGCCT TCCAAGCCCT GGGGCTGCTT 1320

TCTGTGGCTG TGAGGTCTGA GTTTAAGGTC TATTTGCCTC GCGTGCTGGA CATCATCCGA 1380

GCGGCCCTGC CCCCAAAGGA CTTCGCCCAT AAAAGGCAGA AGGCAATGCA GGTGGACGCC 1440

ACAGTCTTCA CTTGCATCAG CATGCTGGCT CGAGCAATGG GGCCAAGCAT CCAGCAGGAT 1500

ATCAAGGAGC TGCTGGAGCC CATGCTGGCA GTAGGACTAA GCCCTGCCCT CACTGCAGTG 1560

CTCTACGACC TGAGTCGTCA GATTCCACAG CTAAAGAAGG ACATTCAAGA TGGGCTACTG 1620

AAAATGCTGT CCCTGGTCCT TATGCACAAA CCACTCCGCC ACCCAGGCAT GCCCAAGGGC 1680

CTGGCCCATC AGCTGGCCTC TCCTGGCCTC ACAACCCTCC CTGAGGCCAG CGATGTGGGC 1740

AGCATCACTC TTGCCCTCCG AACGCTTGGC AGCTTTGAAT TTGAAGGCCA CTCTCTGACC 1800

CAATTTGTTC GCCACTGTGC GGATCATTTT CTAAACAGTG AGCACAAGGA GATCCGCATG 1860

GAGGCTGCCC GTACCTGTTC CCGCCTGCTC ACGCCCTCCA TCCACCTCAT CAGTGGCCAT 1920

GCTCATGTGG TTAGCCAGAC TGCAGTGCAA GTGGTGGCAG ACGTGCTTAG CAAACTGCTC 1980

GTGGTTGGGA TAACAGATCC TGACCCTGAC ATTCGCTATT GTGTCTTGGC ATCCCTGGAC 2040

GAGCGCTTTG ATGCACACCT GGCCCAGGCG GAGAACTTGC AGGCCTTGTT TGTGGCTCTG 2100

AATGACCAGG TGTTTGAGAT CCGGGAGCTG GCCATCTGCA CTGTGGGCCG ACTCAGTAGC 2160

ATGAACCCGG CGTTTGTCAT GCCTTTCCTG CGCAAGATGC TCATCCAGAT TTTGACAGAG 2220

CTGGAGCACA GTGGGATTGG AAGAATCAAA GAGCAGAGTG CCCGCATGCT GGGGCACCTG 2280

GTCTCCAATG CGCCCCGACT CATCCGTCCC TACATGGAGC CTATTCTGAA GGCATTAATT 2340

TTGAAACTGA AAGATCCAGA CCCTGATCCA AACCCAGGTG TGATCAATAA TGTCCTGGCA 2400

ACAATAGGAG AATTGGCACA GGTTAGTGGC CTGGAAATGA GGAAATGGGT TGATGAACTT 2460

TTTATTATCA TTATGGACAT GCTCCAGGAT TCCTCTTTGT TGGCCAAAAG GCAGGTGGCT 2520

CTATGGACCC TGGGACAGTT GGTGGCCAGC ACTGGCTATG TAGTAGAGCC CTACAGGAAG 2580

TACCCTACTT TGCTTGAGGT GCTACTGAAT TTTCTGAAGA CTGAGCAGAA CCAGGGTACA 2640

CGCAGAGAGG CCATCCGTGT GTTAGGGCTT TTAGGGGCTT TGGATCCCTA CAAGCACAAA 2700

GTGAACATTG GCATGATAGA CCAGTCCCGG GATGCCTCTG CTGTCAGCCT GTCAGAATCC 2760

AAGTCAAGTC AGGATTCCTC TGACTATAGC ACTAGTGAAA TGCTGGTTAA CATGGGAAAC 2820

CTGCCTCTGG ATGAGTTCTA CCCAGCTGTG TCCATGGTGG CCCTGATGCG GATCTTCCGA 2880

GACCAGTCAC TCTCTCACCA TCACACCATG GTTGTCCAGG CCATCACCTT CATCTTCAAG 2940

TCCCTGGGAC TCAAATGTGT GCAGTTCCTG CCCCAGGTCA TGCCCACGTT CCTTAATGTC 3000

ATTCGAGTCT GTGATGGGGC CATCCGGGAA TTTTTGTTCC AGCAGCTGGG AATGTTGGTG 3060

TCCTTTGTGA AGAGCCACAT CAGACCTTAT ATGGATGAAA TAGTCACCCT CATGAGAGAA 3120

TTCTGGGTCA TGAATACCTC AATTCAGAGC ACGATCATTC TTCTCATTGA GCAAATTGTG 3180

GTAGCTCTTG GGGGTGAATT TAAGCTTTAC CTGCCCCAGC TGATCCCACA CATGTTGCGT 3240

GTCTTCATGC ATGACAACAG CCCAGGCCGC ATCGTCTCTA TCAAGTTATT GGCTGCAATC 3300

CAGCTGTTTG GCGCCAACCT GGATGACTAC CTACATTTAC TGCTGCCTCC TATTGTGAAG 3360

TTGTTTGATG CCCCTGAAGC TCCACTGCCA TCTCGAAAGG CAGCGCTAGA GACTGTGGAC 3420

CGCCTGACGG AGTCCCTGGA TTTCACTGAC TATGCCTCCC GGATCATTCA CCCTATTGTT 3480

CGAACACTGG ACCAGAGCCC AGAACTGCGC TCCACAGCCA TGGACACGCT GTCTTCACTT 3540

GTTTTTCAAC TGGGGAAGAA GTACCAAATT TTCATTCCAA TGGTGAATAA AGTTCTGGTG 3600

CGACACCGAA TCAATCATCA GCGCTATGAT GTGCTCATCT GCAGAATTGT CAAGGGATAC 3660

ACACTTGCTG ATGAAGAGGA GGATCCTTTG ATTTACCAGC ATCGAATGCT TAGGAGTGGC 3720

CAAGGGGATG CATTGGCTAG TGGACCAGTG GAAACAGGAC CCATGAAGAA ACTGCACGTC 3780

AGCACCATCA ACCTCCAAAA GGCCTGGGGT GCTGCCAGGA GGGTCTCCAA AGATGACTGG 3840

CTGGAATGGC TGAGACGGCT GAGCCTGGAG CTGCTGAAGG ACTCATCATC GCCCTCCCTG 3900

CGCTCCTGCT GGGCCCTGGC ACAGGCCTAC AACCCGATGG CCAGGGATCT CTTCAATGCT 3960

GCGTTTGTGT CCTGCTGGTC TGAATTGAAT GAAGATCAAC AGGATGAGCT CATCAGAAGC 4020

ATCGAGTTGG CCCTCACCTC ACAAGACATC GCTGAAGTCA CACAAACCCT CTTAAACTTG 4080

GCTGAATTCA TGGAACACAG TGACAAGGGC CCCCTGCCAC TGAGAGATGA CAATGGCATT 4140

GTTCTGCTGG GTGAAAGAGC TGCCAAGTGC CGAGCATATG CCAAAGCACT ACACTACAAA 4200

GAACTGGAGT TCCAGAAAGG CCCCACCCCT GCCATTCTAG AATCTCTCAT CAGCATTAAT 4260

AATAAGCTAC AGCAGCCGGA GGCAGCGGCC GGAGTGTTAG AATATGCCAT GAAACACTTT 4320

GGAGAGCTGG AGATCCAGGC TACCTGGTAT GAGAAACTGC ATGAGTGGGA GGATGCCCTG 4380

GTGGCCTATG ACAAGAAAAT GGACACCAAC AAGGATGACC CAGAGCTGAT GCTGGGCCGC 4440

ATGCGCTGCC TCGAGGCCCT GGGGGAATGG GGTCAACTCC ACCAACAGTG CTGTGAAAAG 4500

TGGACCCTGG TTAATGATGA GACCCAAGCC AAGATGGCCC GGATGGCTGC TGCAGCTGCA 4560

TGGGGTTTAG GTCAGTGGGA CAGCATGGAA GAATACACCT GTATGATCCC TCGGGACACC 4620

CATGATGGGG CATTTTATAG AGCTGTGCTG GCACTGCATC AGGACCTCTT CTCCTTGGCA 4680

CAACAGTGCA TTGACAAGGC CAGGGACCTG CTGGATGCTG AATTAACTGC GATGGCAGGA 4740

GAGAGTTACA GTCGGGCATA TGGGGCCATG GTTTCTTGCC ACATGCTGTC CGAGCTGGAG 4800

GAGGTTATCC AGTACAAACT TGTCCCCGAG CGACGAGAGA TCATCCGCCA GATCTGGTGG 4860

GAGAGACTGC AGGGCTGCCA GCGTATCGTA GAGGACTGGC AGAAAATCCT TATGGTGCGG 4920

TCCCTTGTGG TCAGCCCTCA TGAAGACATG AGAACCTGGC TCAAGTACGC AAGCCTGTGT 4980

GGCAAGAGTG GCAGACTGGC TCTTGCTCAT AAAACCTTAG TGTTGCTCCT GGGAGTTGAT 5040

CCATCTCGGC AACTTGACCA TCCCCTGCCG ACAGTTCACC CTCAGGTGAC CTATGCCTAC 5100

ATGAAAAACA TGTGGAAGAG CGCCCGCAAG ATCGATGCCT TCCAGCACAT GCAGCATTTT 5160

GTCCAGACCA TGCAGCAACA GGCCCAGCAT GCCATCGCTA CTGAGGACCA GCAGCATAAG 5220

CAGGAACTGC ACAAGCTCAT GGCCCGATGC TTCCTGAAAC TTGGAGAGTG GCAGCTGAAT 5280

CTACAGGGCA TCAACGAGAG CACAATCCCC AAAGTGCTGC AGTACTACAG CGCTGCCACC 5340

GAGCACGACC GCAGCTGGTA CAAGGCCTGG CACGCGTGGG CAGTGATGAA CTTCGAAGCT 5400

GTGCTACACT ACAAACATCA GAACCAAGCC CGCGACGAGA AGAAGAAACT GCGTCATGCC 5460

AGCGGGGCTA ATATCACCAA CACCACCACT GCCGCCACCA CAGCCGCTAC TGCCACCACC 5520

ACCGCCAGCA CCGAGGGCAG CAACAGTGAG AGCGAGGCCG AGAGCACCGA GAACAGCCCC 5580

ACCCCATCGC CGCTGCAGAA GAAGGTCACT GAGGATCTGT CCAAAACCCT CCTGATGTAC 5640

ACGGTGCCTG CCGTCCAGGG CTTCTTCCGT TCCATCTCGT TGTCACGAGG CAACAACCTC 5700

CAGGATACAC TCAGAGTTCT CACCTTATGG TTTGATTATG GTCACTGGCC AGATGTCAAT 5760

GAGGCCTTAG TGGAAGGAGT GAAAGCCATC CAGATTGATA CCTGGCTACA GGTTATACCT 5820

CAGCTCATTG CAAGAATTGA TACTCCCAGA CCCTTGGTGG GACGTCTCAT TCACCAGCTT 5880

CTCACAGACA TTGGTCGGTA CCACCCCCAG GCCCTCATCT ACCCCCTAAC AGTGGCTTCT 5940

AAGTCCACCA CGACAGCCCG GCACAACGCA GCCAACAAGA TTCTGAAGAA CATGTGTGAG 6000

CACAGCAACA CCCTGGTCCA GCAGGCCATG ATGGTGAGCG AGGAGCTGAT CCGAGTGGCC 6060

ATCCTGTGGC ATGAGATGTG GCACGAAGGC CTGGAAGAGG CATCTCGTTT GTACTTTGGG 6120

GAGAGGAACG TGAAAGGCAT GTTTGAGGTG CTGGAGCCCT TGCATGCTAT GATGGAACGG 6180

GGCCCCCAGA CTCTGAAGGA GACATCCTTT AATCAGGCCT ATGGTCGAGA TTTAATGGAG 6240

GCCCAAGAGT GGTGCAGGAA GTACATGAAA TCAGGGAATG TCAAGGACCT CACTCAAGCC 6300

TGGGACCTCT ATTATCATGT GTTCCGACGA ATCTCAAAGC AGCTGCCTCA GCTCACATCC 6360

TTAGAGCTGC AATATGTTTC CCCAAAACTT CTGATGTGCC GGGACCTTGA ATTGGCTGTG 6420

CCAGGAACAT ATGACCCCAA CCAGCCAATC ATTCGCATTC AGTCCATAGC ACCGTCTTTG 6480

CAAGTCATCA CATCCAAGCA GAGGCCCCGG AAATTGACAC TTATGGGCAG CAACGGGCAT 6540

GAATTTGTTT TCCTTCTAAA AGGCCATGAA GATCTGCGCC AGGATGAGCG TGTGATGCAG 6600

CTCTTCGGCC TGGTTAACAC CCTTCTGGCC AATGACCCAA CATCTCTTCG GAAAAACCTC 6660

AGCATCCAGA GATATGCCGT CATCCCTTTA TCGACCAACT CGGGCCTCAT TGGCTGGGTG 6720

CCCCATTGTG ACACACTGCA CGCCCTCATC CGGGACTACA GGGAGAAGAA GAAGATCCTT 6780

CTCAACATCG AGCATCGCAT CATGTTGCGG ATGGCTCCAG ACTATGACCA CTTGACTCTG 6840

ATGCAGAAGG TGGAGGTGTT TGAGCATGCC GTCAATAATA CAGCTGGGGA CGACCTGGCC 6900

AAGCTGCTGT GGCTGAAAAG CCCCAGCTCT GAGGTGTGGT TTGACCGAAG AACCAATTAT 6960

ACCCGTTCTT TAGCGGTCAT GTCAATGGTT GGGTATATTT TAGGCCTGGG AGATAGTTTT 7020

CCTAAATGGT TTCATTTGTC CCAGCTCTTT GGGAAGCTGA GGAAAGCCAC CTGCTCCACC 7080

TGGCTCCAGG TTGCTATGAC CCGAGAGAAG TTTCCAGAGA AGATTCCATT TAGACTAACA 7140

AGAATGTTGA CCAATGCTAT GGAGGTTACA GGCCTGGATG GCAACTACAG AATCACATGC 7200

CACACAGTGA TGGAGGTGCT GCGGGAGCAC AAGGACAGTG TCATGGCTGT GCTGGAAGCC 7260

TTTGTCTATG ACCCCTTGCT GAACTGGAGG CTGATGGACA CAAATACCAA AGGCAACAAG 7320

CGATCCCGAA CGAGGACGGA TTCCTACTCT GCCGGCCAGT CAGTCGAAAT TTTGGACGGT 7380

GTGGAACTTG GGGAGCCAGC CCATAAGAAA ACGGGGACCA CAGTGCCAGA ATCTATTCAT 7440

TCTTTCATTG GAGACGGTTT GGTGAAACCA GAGGCCCTAA ATAAGAAAGC TATTCAGATT 7500

ATTAACAGGG TTCGAGATAA GCTCACTGGT CGGGACTTCT CTCATGATGA CACTTTGGAT 7560

GTTCCAACGC AAGTTGAGCT GCTCATCAAA CAAGCGACAT CCCATGAAAA CCTCTGCCAG 7620

TGCTATATTG GCTGGTGCCC TTTCTGGTAA 7650

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i+++++++++++skq+p+kl+l+Gs+g+e+++L+kg+eDlrqderv+qlf+lvNtlLa+d

Q: 2153  IQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND  2212

         899*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkklvekkavlldqpisyrykdl  120

         +++ r++L+i++y+V+plst+sgli+wv+++++L++l+++++ekk++ll+        ++

Q: 2213  PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHALIRDYREKKKILLN-------IEH  2265

         *************************************************9.......9**

S: 121   stvqarkpklkhlkls..levfkevlenlvpkdllkklllekfpspeewfelrkaytrsl  178

         +++ +++p+++hl+l+  +evf+++++n ++ d l+kll+ k+ps+e+wf++r++ytrsl

Q: 2266  RIMLRMAPDYDHLTLMqkVEVFEHAVNN-TAGDDLAKLLWLKSPSSEVWFDRRTNYTRSL  2324

         ****************************.999****************************

S: 179   AvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpekvPFRLTrniv  238

         Av+s+vgyiLgLgd  ++ + + q  g++  +     ++ a+t++k+pek+PFRLTr+++

Q: 2325  AVMSMVGYILGLGDSFPKWFHLSQLFGKLRKATCSTWLQVAMTREKFPEKIPFRLTRMLT  2384

         ************************************************************

S: 239   nalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkkkkktsketeeela  298

         na++vtg++G++r++c++v++vlre+k++++++Le+f+ydpl++w+ +++++k+++++++

Q: 2385  NAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRT  2444

         ************************************************************

S: 299   ekakaealkikkllskvekaenavatrdlllle  331

         ++++++a +++++l++ve +e+a+++++++++e

Q: 2445  RTDSYSAGQSVEILDGVELGEPAHKKTGTTVPE  2477

         ****************************99987

Domain Sequence
(FASTA)

IQSIAPSLQV ITSKQRPRKL TLMGSNGHEF VFLLKGHEDL RQDERVMQLF GLVNTLLAND 60

PTSLRKNLSI QRYAVIPLST NSGLIGWVPH CDTLHALIRD YREKKKILLN IEHRIMLRMA 120

PDYDHLTLMQ KVEVFEHAVN NTAGDDLAKL LWLKSPSSEV WFDRRTNYTR SLAVMSMVGY 180

ILGLGDSFPK WFHLSQLFGK LRKATCSTWL QVAMTREKFP EKIPFRLTRM LTNAMEVTGL 240

DGNYRITCHT VMEVLREHKD SVMAVLEAFV YDPLLNWRLM DTNTKGNKRS RTRTDSYSAG 300

QSVEILDGVE LGEPAHKKTG TTVPE 325

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005829	; C:cytosol
GO:0012505	; C:endomembrane system
GO:0005764	; C:lysosome
GO:0016020	; C:membrane
GO:0016605	; C:PML body
GO:0005524	; F:ATP binding
GO:0008144	; F:drug binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0043022	; F:ribosome binding
GO:0001030	; F:RNA polymerase III type 1 promoter DNA binding
GO:0001031	; F:RNA polymerase III type 2 promoter DNA binding
GO:0001032	; F:RNA polymerase III type 3 promoter DNA binding
GO:0071456	; P:cellular response to hypoxia
GO:0031669	; P:cellular response to nutrient levels
GO:0007281	; P:germ cell development
GO:0045792	; P:negative regulation of cell size
GO:0016242	; P:negative regulation of macroautophagy
GO:0051534	; P:negative regulation of NFAT protein import into nucleus
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0018107	; P:peptidyl-threonine phosphorylation
GO:0030838	; P:positive regulation of actin filament polymerization
GO:0010592	; P:positive regulation of lamellipodium assembly
GO:0046889	; P:positive regulation of lipid biosynthetic process
GO:0050731	; P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0051496	; P:positive regulation of stress fiber assembly
GO:0045945	; P:positive regulation of transcription from RNA polymerase III promoter
GO:0045859	; P:regulation of protein kinase activity
GO:0032314	; P:regulation of Rac GTPase activity
GO:0043200	; P:response to amino acid stimulus
GO:0032868	; P:response to insulin stimulus
GO:0031529	; P:ruffle organization
GO:0031929	; P:TOR signaling cascade

KEGG

InterPros

IPR011989	; ARM-like.
IPR016024	; ARM-type_fold.
IPR024585	; DUF3385_TOR.
IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.
IPR009076	; Rapamycin-bd_dom.
IPR026683	; TOR/Smg1.

Pfam

PF11865	; DUF3385; 1.
PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.
PF08771	; Rapamycin_bind; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013