EKS-MAM-00288

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00288

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/STKR	331.9	5.5E-99	204	505	302

Status

Unreviewed

Ensembl Protein

ENSMMUP00000026355

UniProt Accession

F7GDJ3;

Protein Name

Protein Synonyms/Alias

Anti-Muellerian hormone type-2 receptor;

Gene Name

AMHR2

Gene Synonyms/Alias

AMHR2; EGK_03711;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000020037	ENSMMUP00000026356	ENSMMUT00000028169
ENSMMUG00000020037	ENSMMUP00000026355	ENSMMUT00000028168

Organism

Macaca mulatta

Functional Description

Protein Length

572

Protein Sequence
(FASTA)

MLGSLGLWAL LPTAVEAPPN RRTCVFFEAP GVQGSTKTLG ELLDTGPELP RAIRCLYSRC 60

CFGIWNLTQD RAQVEMQGCR DSDEPGCESL HCDPSPRAHP SPGSTLFTCS CGTDFCNANY 120

SHLPPPGSPG TPGSQGPQAA PGESIWMALV LLGLFLLLLL LLGSIILALL QRKNYRVRSE 180

PVPKPGPDLG RDWSVELQEL PELCFSQVIR EGGHAVVWAG QLQGKLVAIK AFPPRSVAQF 240

QAERALYELP GLQHDHIVRF ITASWGGPGP MLSGPLLVLE LHPKGSLYHY LTQHTSDWGS 300

SLRMALSLAQ GLAFLHEERW QNGQYKPGIA HRDLSSQNVL IREDGSCAIG DLGLALVLPG 360

LTQPPAWTPT QPQGPAAIME AGTQRYMAPE LLDKTLDLQD WGMALRRADI YSLALLLWEI 420

LSRCPDLRPD SSPPPFQLAY EAELGNTPTS DELWALAVQE RRRPYIPSTW RCFATDPDGL 480

RELLEDCWDA DPEARLTAEC VQQRLAALAH PQESPFPESC PRGCTPLCPE DCTSTPAPTI 540

LPCRPQRSAC HFNVQQGPCS RNPQPACTLS PM 572

Nucleotide Sequence
(FASTA)

ATGCTAGGGT CTCTGGGGCT TTGGGCATTA CTTCCCACAG CTGTGGAAGC ACCCCCAAAC 60

AGGCGAACTT GTGTGTTCTT TGAGGCCCCT GGAGTGCAGG GAAGCACAAA GACACTGGGA 120

GAGCTGCTAG ATACAGGCCC AGAGCTCCCT AGAGCTATCC GCTGCCTCTA CAGCCGCTGC 180

TGCTTTGGGA TCTGGAACCT GACCCAAGAC CGGGCACAGG TGGAAATGCA AGGATGCCGA 240

GACAGTGATG AGCCAGGCTG TGAGTCCCTC CACTGTGACC CAAGTCCCCG AGCCCACCCC 300

AGCCCTGGCT CCACTCTCTT CACCTGCTCC TGTGGCACTG ACTTCTGCAA TGCCAATTAC 360

AGCCATCTGC CTCCTCCAGG GAGCCCTGGG ACTCCTGGCT CCCAGGGTCC CCAGGCTGCC 420

CCAGGTGAGT CCATCTGGAT GGCACTGGTG CTGCTGGGGC TGTTCCTCCT CCTCCTGCTG 480

CTGCTGGGCA GCATCATCTT GGCCCTGCTA CAGCGAAAGA ACTACAGAGT GCGAAGTGAA 540

CCAGTGCCAA AGCCAGGGCC AGACTTGGGC AGGGACTGGA GTGTGGAGCT GCAGGAGCTG 600

CCCGAGCTGT GCTTCTCCCA GGTAATCCGG GAAGGAGGTC ATGCAGTGGT TTGGGCCGGG 660

CAGCTGCAAG GCAAACTGGT TGCCATCAAG GCCTTTCCAC CGAGGTCTGT GGCTCAGTTC 720

CAAGCTGAGA GAGCATTGTA CGAACTTCCA GGCCTACAGC ACGACCACAT TGTCCGATTT 780

ATCACCGCCA GCTGGGGGGG CCCTGGCCCC ATGCTCTCTG GGCCCCTGCT GGTACTGGAA 840

CTGCATCCCA AGGGCTCCCT GTACCACTAC TTGACCCAGC ACACCAGTGA CTGGGGAAGT 900

TCCCTGCGGA TGGCACTGTC CCTGGCCCAG GGCCTGGCAT TTCTCCATGA AGAGCGCTGG 960

CAGAATGGCC AATATAAACC AGGTATTGCC CACCGAGATC TGAGCAGCCA GAATGTGCTC 1020

ATTCGGGAAG ATGGATCGTG TGCCATTGGA GACCTGGGCC TTGCCTTGGT GCTCCCTGGC 1080

CTCACTCAGC CCCCTGCCTG GACCCCTACT CAACCACAAG GCCCAGCTGC CATCATGGAA 1140

GCTGGCACCC AGAGGTACAT GGCACCAGAG CTCTTGGACA AGACTCTGGA CCTACAAGAT 1200

TGGGGCATGG CCCTCCGACG AGCTGATATT TACTCTTTGG CTCTGCTCCT GTGGGAGATA 1260

CTGAGCCGCT GCCCAGATTT GAGGCCTGAC AGCAGTCCAC CACCCTTCCA ACTGGCCTAT 1320

GAGGCAGAAC TGGGCAATAC CCCTACCTCT GATGAGCTAT GGGCCTTGGC AGTGCAAGAG 1380

AGGAGGCGTC CCTACATCCC ATCCACCTGG CGCTGCTTTG CTACAGATCC TGATGGGCTG 1440

AGGGAGCTCC TAGAAGACTG TTGGGATGCA GACCCAGAAG CACGGCTGAC GGCTGAGTGT 1500

GTACAGCAGC GCCTGGCTGC CCTGGCCCAT CCTCAGGAGA GCCCCTTTCC GGAGAGCTGT 1560

CCACGTGGCT GCACACCTCT CTGCCCAGAA GACTGTACTT CAACTCCTGC CCCTACCATC 1620

CTGCCCTGTA GGCCTCAGCG GAGTGCCTGC CACTTCAATG TTCAGCAAGG CCCTTGTTCC 1680

AGGAATCCTC AGCCTGCCTG TACCCTTTCT CCTATGTAA 1719

Domain Profile

S: 2     klleligkGrygeVwkaklrgeevAvKifstedeaswkrEkeiyqtvllrhenilqfiaa  61

          ++++i++G ++ Vw+++l+g+ vA+K+f+ ++ a++++E+++y+++ l+h++i++fi+a

Q: 204   CFSQVIREGGHAVVWAGQLQGKLVAIKAFPPRSVAQFQAERALYELPGLQHDHIVRFITA  263

         57899*******************************************************

S: 62    dk.keedsltelllvteyhekgsLsdyLkretldveellrlalslasGlahLHeeivgtk  120

                +l+  llv+e+h+kgsL++yL+++t+d+ ++lr+alsla+Gla+LHee ++++

Q: 264   SWgGPGPMLSGPLLVLELHPKGSLYHYLTQHTSDWGSSLRMALSLAQGLAFLHEE-RWQN  322

         **88899999*********************************************.8999

S: 121   gkkKpaiaHRDlkskNilvkkdltcciaDlGLalkleeekee........ldlaansqvG  172

         g++Kp iaHRDl+s+N+l+++d++c+i+DlGLal l   ++         +  aa++++G

Q: 323   GQYKPGIAHRDLSSQNVLIREDGSCAIGDLGLALVLPGLTQPpawtptqpQGPAAIMEAG  382

         **********************************87776666688888888899******

S: 173   tkRYmaPEvleealnlkdfe.afkraDvYslgLvlWEvasRcee..vdeeveeyklpfee  229

         t+RYmaPE+l+++l+l+d+  a++raD+Ysl+L+lWE++sRc +  +d++ ++++l++e+

Q: 383   TQRYMAPELLDKTLDLQDWGmALRRADIYSLALLLWEILSRCPDlrPDSSPPPFQLAYEA  442

         *******************99***********************999*************

S: 230   vvgsdPsleemkevvvekklrPkipeawkkke.alkelsklleecWdadpeaRltalrvk  288

         ++g++P+ +e++++ v+++ rP ip++w++ + + + l++lle+cWdadpeaRlta++v+

Q: 443   ELGNTPTSDELWALAVQERRRPYIPSTWRCFAtDPDGLRELLEDCWDADPEARLTAECVQ  502

         ******************************98789*************************

S: 289   krl  291

+rl

Q: 503   QRL  505

Domain Sequence
(FASTA)

CFSQVIREGG HAVVWAGQLQ GKLVAIKAFP PRSVAQFQAE RALYELPGLQ HDHIVRFITA 60

SWGGPGPMLS GPLLVLELHP KGSLYHYLTQ HTSDWGSSLR MALSLAQGLA FLHEERWQNG 120

QYKPGIAHRD LSSQNVLIRE DGSCAIGDLG LALVLPGLTQ PPAWTPTQPQ GPAAIMEAGT 180

QRYMAPELLD KTLDLQDWGM ALRRADIYSL ALLLWEILSR CPDLRPDSSP PPFQLAYEAE 240

LGNTPTSDEL WALAVQERRR PYIPSTWRCF ATDPDGLREL LEDCWDADPE ARLTAECVQQ 300

RL 302

Keyword

Complete proteome; Receptor; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>

Gene Ontology

GO:0016020	; C:membrane
GO:0005524	; F:ATP binding
GO:0042562	; F:hormone binding
GO:0005024	; F:transforming growth factor beta-activated receptor activity
GO:0007548	; P:sex differentiation
GO:0007178	; P:transmembrane receptor protein serine/threonine kinase signaling pathway

KEGG

mcc:702822

;

InterPros

IPR000472	; Activin_rcpt.
IPR015771	; Anti-muellerian_hrmn_rcpt_II.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF01064	; Activin_recp; 1.
PF00069	; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013