EKS-MAM-00015

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00015

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	509.2	4.5E-153	1	260	260

Status

Unreviewed

Ensembl Protein

ENSMMUP00000027474

UniProt Accession

H9ETG8;

Protein Name

Protein Synonyms/Alias

Phosphorylase b kinase gamma catalytic chain, testis/liver isoform isoform 1;

Gene Name

PHKG2

Gene Synonyms/Alias

PHKG2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000020878	ENSMMUP00000027474	ENSMMUT00000029361
ENSMMUG00000020878	ENSMMUP00000032456	ENSMMUT00000039379

Organism

Macaca mulatta

Functional Description

Protein Length

375

Protein Sequence
(FASTA)

RGVSSVVRRC VHRATGHEFA VKIMEVTAER LSPEQLEEVR EATQRETHIL RQVAGHPHII 60

TLIDSYESSS FMFLVFDLMR KGELFDYLTE KVALSEKETR SIMRSLLEAV SFLHANNIVH 120

RDLKPENILL DDNMQIRLSD FGFSCHLEPG EKLRELCGTP GYLAPEILKC SMDETHPGYG 180

KEVDLWACGV ILFTLLAGSP PFWHRRQILM LRMIMEGQYQ FSSPEWDDRS STVKDLISRL 240

LQVDPEARLT AEQALQHPFF ERCEGSQSWN LTPRQRFRVA VWTVLAAGRV ALSTHRVRPL 300

TKNALLRDPY ALRSVRRLID NCAFRLYGHW VKKGEQQNRA ALFQHRPPGP FPIMGPEEEG 360

DSAAITEDEA VLVLG 375

Nucleotide Sequence
(FASTA)

AGAGGAGTGA GCTCTGTGGT CCGCCGTTGT GTTCATCGAG CTACTGGCCA CGAGTTTGCC 60

GTGAAGATTA TGGAAGTGAC AGCTGAGCGA CTGAGTCCTG AGCAGCTGGA GGAGGTGCGG 120

GAAGCCACAC AGCGAGAAAC ACACATCCTT CGCCAGGTCG CCGGCCACCC CCACATCATC 180

ACCCTCATCG ATTCCTACGA GTCTTCTAGC TTCATGTTCC TGGTGTTTGA CCTGATGCGG 240

AAGGGAGAGC TGTTTGACTA TCTCACAGAG AAGGTAGCCC TCTCAGAAAA GGAAACCAGG 300

TCCATCATGC GGTCTCTGCT GGAAGCAGTG AGCTTTCTCC ATGCCAACAA CATTGTGCAT 360

CGAGATCTGA AGCCCGAGAA TATTCTCCTA GATGACAATA TGCAGATCCG ACTTTCAGAT 420

TTCGGGTTCT CCTGCCACTT GGAACCTGGC GAGAAGCTTC GAGAGTTGTG TGGGACCCCA 480

GGGTATCTAG CGCCAGAGAT CCTTAAATGC TCCATGGATG AAACCCACCC AGGCTACGGC 540

AAGGAGGTCG ACCTCTGGGC CTGTGGGGTG ATCTTGTTCA CACTCCTGGC TGGCTCGCCA 600

CCCTTCTGGC ACCGGCGGCA GATCCTGATG TTACGCATGA TCATGGAGGG CCAGTACCAG 660

TTCAGTTCCC CTGAGTGGGA CGACCGTTCC AGCACTGTCA AAGACTTGAT TTCCAGGCTG 720

CTGCAGGTGG ATCCTGAAGC ACGCCTGACA GCTGAGCAGG CCCTACAGCA CCCCTTCTTT 780

GAGCGTTGTG AAGGCAGCCA ATCCTGGAAC CTCACCCCCC GCCAGCGGTT CCGGGTGGCA 840

GTGTGGACAG TGCTGGCTGC TGGACGAGTG GCCCTAAGCA CCCATCGTGT ACGGCCACTG 900

ACTAAGAACG CACTGTTGAG GGACCCTTAT GCGCTGCGGT CAGTGCGGCG CCTCATCGAC 960

AACTGTGCCT TCCGGCTCTA TGGACACTGG GTGAAGAAAG GGGAGCAGCA GAACCGGGCA 1020

GCTCTTTTTC AGCACCGGCC CCCTGGGCCT TTTCCCATCA TGGGCCCTGA GGAGGAGGGA 1080

GACTCTGCTG CTATAACTGA GGATGAGGCC GTGCTGGTAC TGGGCTAG 1128

Domain Profile

S: 9     rGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrqvsGhpsii  68

         rGvssvvrrc+++atg+efavki++v+ae+ls+e+++e+reat++e++ilrqv+Ghp+ii

Q: 1     RGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATQRETHILRQVAGHPHII  60

         9***********************************************************

S: 69    klkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleaveylhaknivh  128

         +l+d+yesssf+flvfdlm+kGelfdyltekv+lseketr+imr+lleav++lha+nivh

Q: 61    TLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVH  120

         ************************************************************

S: 129   rdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsmdeeapGys  188

         rdlkpenillddn++i+lsdfGfs++le+GeklrelcGtpgylapeilkcsmde++pGy+

Q: 121   RDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYG  180

         ************************************************************

S: 189   kevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddiseevkdliskl  248

         kevdlwa+Gvil+tllaGsppfwhr+q+lmlr+imeG+yqf+spewdd+s++vkdlis+l

Q: 181   KEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRL  240

         ************************************************************

S: 249   lvvdpekrltaeealahpff  268

         l+vdpe+rltae+al+hpff

Q: 241   LQVDPEARLTAEQALQHPFF  260

         *******************8

Domain Sequence
(FASTA)

RGVSSVVRRC VHRATGHEFA VKIMEVTAER LSPEQLEEVR EATQRETHIL RQVAGHPHII 60

TLIDSYESSS FMFLVFDLMR KGELFDYLTE KVALSEKETR SIMRSLLEAV SFLHANNIVH 120

RDLKPENILL DDNMQIRLSD FGFSCHLEPG EKLRELCGTP GYLAPEILKC SMDETHPGYG 180

KEVDLWACGV ILFTLLAGSP PFWHRRQILM LRMIMEGQYQ FSSPEWDDRS STVKDLISRL 240

LQVDPEARLT AEQALQHPFF 260

Keyword

ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013