EPS-MAM-00013

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MAM-00013

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	69.8	3.7E-19	122	200	79

Status

Unreviewed

Ensembl Protein

ENSMMUP00000028362

UniProt Accession

F7FAZ4;

Protein Name

Protein Synonyms/Alias

Gene Name

DUSP11

Gene Synonyms/Alias

DUSP11;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000021537	ENSMMUP00000036480	ENSMMUT00000043478
ENSMMUG00000021537	ENSMMUP00000028362	ENSMMUT00000030309

Organism

Macaca mulatta

Functional Description

Protein Length

330

Protein Sequence
(FASTA)

MSQWHHPRSG WGRGRDFSGR SSAKKKGGNH IPERWKDYLP VGQRMPGTRF IAFKVPLQKS 60

FEKKLAPEEC FSPLDLFNKI REQNEELGLI IDLTYTQRYY KPEDLPESVP YLKIFTVGHQ 120

VPDDETIFKF KHAVNGFLKE NKDNDKLIGV HCTHGLNRTG YLICRYLIDV EGMRPDDAIE 180

LFNRCRGHCL ERQNYIEDLQ NGPIRKNWNS SVPRSSFEDS AHLMQPVHTM NKPVKRGPRY 240

NLHQIQGHST RHFHTQTQNL QQRVRKFSQN PHVYQRGHLP PPGPPGEDCS RRRYSWNVKP 300

NASLAAQDRR RWYPDNYSGL SYPAYWEWTQ 330

Nucleotide Sequence
(FASTA)

ATGAGCCAGT GGCATCATCC CCGCAGTGGC TGGGGTCGGG GACGCGACTT TTCAGGACGC 60

TCCTCCGCCA AGAAGAAGGG CGGAAACCAC ATCCCGGAAA GGTGGAAAGA CTATCTCCCA 120

GTTGGACAGC GGATGCCTGG GACTCGTTTC ATTGCTTTCA AAGTTCCTTT GCAAAAGAGT 180

TTTGAAAAGA AACTTGCTCC GGAAGAATGC TTTTCCCCTT TGGATCTTTT TAACAAAATC 240

CGAGAACAAA ATGAAGAACT TGGACTGATT ATTGATTTAA CATATACTCA ACGCTATTAT 300

AAACCGGAGG ATTTGCCAGA ATCTGTTCCT TACTTAAAAA TATTTACAGT TGGACATCAA 360

GTGCCTGATG ACGAGACTAT TTTTAAATTC AAACACGCTG TTAATGGGTT TTTGAAAGAA 420

AATAAAGATA ATGACAAACT TATTGGTGTC CACTGTACTC ATGGTTTAAA CAGGACCGGC 480

TACCTTATTT GCAGATATTT GATTGATGTA GAAGGCATGA GGCCAGATGA TGCAATTGAA 540

TTATTCAATA GGTGCCGGGG ACATTGCTTA GAAAGACAAA ACTACATTGA AGACCTTCAG 600

AATGGTCCTA TCAGAAAGAA TTGGAATTCC AGTGTACCCA GGTCAAGTTT TGAAGACTCA 660

GCACATCTCA TGCAACCAGT CCACACCATG AATAAGCCTG TTAAACGAGG ACCTAGGTAT 720

AATCTACATC AGATCCAGGG TCACTCAACT CGACATTTCC ACACCCAGAC CCAAAATTTG 780

CAACAAAGAG TCAGAAAATT TTCACAGAAT CCACATGTTT ACCAGAGAGG CCATCTCCCT 840

CCTCCTGGTC CTCCTGGAGA GGACTGTTCA CGCAGGAGGT ACTCTTGGAA TGTGAAGCCC 900

AATGCCAGTC TGGCAGCCCA GGATAGAAGA AGGTGGTATC CTGACAATTA CTCTGGACTC 960

TCCTATCCAG CCTATTGGGA ATGGACCCAG TGA 993

Domain Profile

S: 61    dDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveglslsdAi  120

            d++ ++++ ++++ f++e+k++++ + vHC++G++R+++l++ YL++veg++ +dAi

Q: 122   P--DDETIFKFKHAVNGFLKENKDNDKLIGVHCTHGLNRTGYLICRYLIDVEGMRPDDAI  179

         3..45789****************************************************

S: 121   eavkrkrpsiepnegfleQLl  141

         e ++r+r+++ ++++++e L

Q: 180   ELFNRCRGHCLERQNYIEDLQ  200

         *****************9986

Domain Sequence
(FASTA)

PDDETIFKFK HAVNGFLKEN KDNDKLIGVH CTHGLNRTGY LICRYLIDVE GMRPDDAIEL 60

FNRCRGHCLE RQNYIEDLQ 79

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Taeniopygia guttata"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013