EKS-MAM-00130

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MAM-00130

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/ABC1	418.4	3.4E-125	82	386	305

Status

Unreviewed

Ensembl Protein

ENSMMUP00000031106

UniProt Accession

F7H1U5;

Protein Name

Protein Synonyms/Alias

AarF domain containing kinase 1 isoform a; Putative aarF domain-containing protein kinase 1 isoform a;

Gene Name

ADCK1

Gene Synonyms/Alias

ADCK1; EGK_18427;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMMUG00000023627	ENSMMUP00000031104	ENSMMUT00000033238
ENSMMUG00000023627	ENSMMUP00000031106	ENSMMUT00000033240

Organism

Macaca mulatta

Functional Description

Protein Length

455

Protein Sequence
(FASTA)

MARKALKLAS WTSMALAASG IYLYSNKYLD PNDFGAVRVG RAVATTAVIS YDYLTSLKSV 60

PYGSEEYLQL RSKIHDLFQS FDDTPLGTAS LAQVHKAVLH DGRTVAVKVQ HPKVRAQSSK 120

DILLMEVLIL AVKQLFPEFE FMWLVDEAKK NLPLELDFLN EGRNAEKVSQ MLKHFDFLKV 180

PRIHWDLSTE RVLLMEFVDG GQVNDRDYME KNKIDVNEIS RHLGKMYSEM IFVNGFVHCD 240

PHPGNVLVRK HPGTGKAEIV LLDHGLYQVL TEEFRLNYCH LWQSLIWTDM KRVKEYSQRL 300

GAGDLYPLFA CMLTARSWNS VNRGISQAPV TATEDLEIRN NAANYLPQIS QLLNHVPRQM 360

LLILKTNDLL RGIEAALGTR ASASSFLNMS RCCIRALAEH KKKNTCSFFR RTQISFREAF 420

NLWQINLHEL ILRVKGLKLA DRVLALICWL FPAPL 455

Nucleotide Sequence
(FASTA)

ATGGCCAGAA AGGCTCTCAA GCTTGCTTCA TGGACCAGCA TGGCTCTTGC TGCTTCTGGC 60

ATCTACCTCT ACAGTAACAA GTACTTGGAC CCTAATGACT TTGGCGCTGT CAGGGTGGGC 120

AGAGCAGTTG CTACGACGGC TGTCATCAGT TATGACTACC TCACTTCCCT GAAGAGTGTC 180

CCCTATGGCT CAGAGGAGTA CTTGCAGCTG AGATCTAAGA TCCATGATTT GTTCCAGAGC 240

TTCGACGACA CCCCTCTGGG GACTGCCTCC CTGGCCCAGG TCCACAAGGC AGTGCTGCAT 300

GATGGGCGGA CGGTGGCCGT GAAGGTCCAG CACCCAAAGG TGCGGGCTCA GAGCTCGAAG 360

GACATTCTCC TGATGGAGGT GCTCATTCTG GCTGTGAAGC AGCTATTCCC AGAGTTTGAG 420

TTTATGTGGC TTGTGGATGA AGCCAAGAAG AACCTGCCTT TGGAGCTGGA TTTCCTCAAT 480

GAAGGGAGGA ATGCTGAGAA GGTGTCCCAG ATGCTCAAGC ATTTTGACTT CTTGAAGGTG 540

CCCCGAATCC ACTGGGACCT GTCCACGGAG CGGGTCCTCC TGATGGAGTT TGTGGACGGC 600

GGGCAGGTCA ATGACAGAGA CTACATGGAG AAGAACAAGA TCGACGTCAA TGAGATCTCA 660

CGCCACCTGG GCAAGATGTA TAGTGAGATG ATCTTCGTCA ATGGCTTCGT GCACTGCGAT 720

CCCCACCCCG GCAATGTACT GGTGCGGAAG CACCCTGGCA CGGGAAAGGC GGAGATTGTC 780

CTGTTGGACC ATGGGCTTTA CCAGGTGCTC ACGGAGGAAT TCCGCCTGAA TTACTGCCAC 840

CTCTGGCAGT CTCTGATCTG GACTGACATG AAGAGAGTGA AGGAGTACAG CCAGCGCCTG 900

GGAGCCGGGG ATCTCTACCC CTTGTTTGCC TGCATGCTGA CAGCGCGGTC ATGGAACTCA 960

GTCAACAGAG GCATCAGCCA AGCTCCCGTC ACTGCCACTG AGGACTTAGA GATTCGCAAC 1020

AACGCGGCCA ACTACCTCCC CCAGATCAGC CAGCTCCTTA ACCACGTGCC ACGCCAGATG 1080

CTGCTCATCT TGAAGACCAA TGACCTGCTG CGTGGCATCG AGGCCGCCCT GGGCACCCGT 1140

GCCAGCGCCA GCTCCTTTCT CAACATGTCA CGTTGCTGCA TCAGAGCGCT AGCCGAGCAC 1200

AAGAAGAAGA ATACCTGTTC ATTCTTCAGA AGAACCCAGA TCTCTTTCAG AGAGGCCTTC 1260

AACTTATGGC AGATCAACCT CCATGAGCTC ATCCTGCGTG TGAAGGGGTT GAAGCTGGCT 1320

GACCGGGTCT TGGCCCTAAT ATGCTGGCTG TTCCCTGCTC CACTCTGA 1368

Domain Profile

S: 1     eekPlaaASlaqvhkArLkdGeeVAVKvqypgvkesidsDlktlelllkvlevlfkdlkl  60

         +++Pl++ASlaqvhkA+L+dG++VAVKvq+p+v++++++D+ ++e+l+ ++++lf+++++

Q: 82    DDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEVLILAVKQLFPEFEF  141

         689*********************************************************

S: 61    ewlvdelkkeLaleldferEarnaekfrkllkkfkalkvPkvleelstkrvLtmelvegv  120

         +wlvde+kk+L+leldf++E+rnaek++++lk+f++lkvP+++++lst+rvL+me+v+g

Q: 142   MWLVDEAKKNLPLELDFLNEGRNAEKVSQMLKHFDFLKVPRIHWDLSTERVLLMEFVDGG  201

         ************************************************************

S: 121   pvddleyiessqilrneiaekliklllkeifvdnfvhtDphpgNvlvqksskegklelvL  180

         +v+d +y+e+++i++nei+++l k+++++ifv++fvh+DphpgNvlv+k++++gk+e+vL

Q: 202   QVNDRDYMEKNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVL  261

         ************************************************************

S: 181   LDfGlsrelsekfrrlyikllkavvdrDrkkvkkksqrlaeltgeeaklladalvervlt  240

         LD+Gl++ l+e+fr +y++l+++++++D+k+vk++sqrl+  +g+ ++l+a++l++r+++

Q: 262   LDHGLYQVLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRLG--AGDLYPLFACMLTARSWN  319

         ****************************************..******************

S: 241   lgeafasqarkeveeleklaverlessllkllmevlvklprevllilktidllrgieeaL  300

         ++++++sq  ++v+++e+l+++++++++l+++++ l+++pr++llilkt+dllrgie+aL

Q: 320   SVNRGISQ--APVTATEDLEIRNNAANYLPQISQLLNHVPRQMLLILKTNDLLRGIEAAL  377

         ********..**************************************************

S: 301   kakldilel  309

         +++++++++

Q: 378   GTRASASSF  386

         ***998765

Domain Sequence
(FASTA)

DDTPLGTASL AQVHKAVLHD GRTVAVKVQH PKVRAQSSKD ILLMEVLILA VKQLFPEFEF 60

MWLVDEAKKN LPLELDFLNE GRNAEKVSQM LKHFDFLKVP RIHWDLSTER VLLMEFVDGG 120

QVNDRDYMEK NKIDVNEISR HLGKMYSEMI FVNGFVHCDP HPGNVLVRKH PGTGKAEIVL 180

LDHGLYQVLT EEFRLNYCHL WQSLIWTDMK RVKEYSQRLG AGDLYPLFAC MLTARSWNSV 240

NRGISQAPVT ATEDLEIRNN AANYLPQISQ LLNHVPRQML LILKTNDLLR GIEAALGTRA 300

SASSF 305

Keyword

Complete proteome; Kinase; Reference proteome; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>