EKS-MOD-00419

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00419

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	529.4	1.9E-159	33	290	258

Status

Unreviewed

Ensembl Protein

ENSMODP00000001513

UniProt Accession

F7CJ36;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK2

Gene Synonyms/Alias

SGK2;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000001260	ENSMODP00000001513	ENSMODT00000001545

Organism

Monodelphis domestica

Functional Description

Protein Length

362

Protein Sequence
(FASTA)

MDPPASPNLQ TSTPNGNINL GPSANPNARP TDFDFLKVIG KGNYGKVLLA KRKSDGKFYA 60

VKVLQKKSIL KKKEQNHIMA ERNVLLKNVT HPFLVGLRYS FQTSEKLYFV LDYVNGGELF 120

FHLQREHCFL EPRARFYAAE VASAIGYLHS LNIIYRDLKP ENILLDCQGH VVLTDFGLCK 180

EGMEPEETTS TFCGTPEYLA PEVLRKQPYD RTVDWWCLGA VLYEMLCGLP PFYSRDVSEM 240

YENILHKPLQ IQGGKTVAAC DLLHGLLHKD QKKRLGAKAD FLEIKNHVFF SPINWDDLYH 300

KRLTPPFNPN VVGPADLRHF DPEFTKEAIS SSIGHTPDLT ASSCGASSAF LGFSYAPGDE 360

NF 362

Nucleotide Sequence
(FASTA)

ATGGATCCTC CTGCCAGTCC TAACCTCCAG ACTTCAACAC CCAATGGAAA TATCAACTTG 60

GGACCTTCAG CAAATCCAAA TGCAAGACCA ACAGACTTTG ATTTTCTGAA AGTGATTGGA 120

AAGGGGAACT ATGGAAAAGT TCTCTTGGCC AAAAGGAAGT CTGATGGAAA GTTTTATGCT 180

GTCAAAGTCT TACAGAAAAA ATCCATCTTG AAAAAGAAAG AGCAAAATCA CATCATGGCA 240

GAACGTAATG TGCTCCTAAA GAATGTGACG CACCCTTTCC TGGTGGGCCT CCGCTACTCC 300

TTTCAGACTT CAGAGAAGCT CTATTTTGTC CTAGACTACG TCAATGGAGG AGAGCTCTTC 360

TTCCACTTGC AGAGAGAGCA CTGTTTTCTA GAACCTCGAG CTCGATTTTA TGCTGCTGAG 420

GTGGCCAGTG CTATAGGCTA CTTGCATTCT CTGAACATCA TCTACAGGGA CTTGAAACCA 480

GAGAACATTC TCTTGGATTG CCAGGGCCAT GTTGTATTGA CTGATTTTGG GCTTTGTAAA 540

GAAGGAATGG AACCAGAAGA AACCACATCT ACTTTCTGTG GCACCCCAGA GTATTTGGCT 600

CCAGAAGTAC TGAGAAAACA ACCTTATGAC CGAACAGTAG ATTGGTGGTG TTTGGGAGCT 660

GTTCTTTATG AAATGCTCTG TGGCTTGCCA CCTTTCTACA GCCGAGATGT TTCTGAAATG 720

TATGAGAACA TCCTTCACAA GCCTCTCCAG ATCCAAGGAG GCAAGACGGT GGCAGCCTGT 780

GATCTCCTGC ATGGCCTTCT CCACAAGGAT CAGAAGAAAA GGCTGGGTGC CAAAGCAGAT 840

TTTCTTGAGA TAAAGAATCA TGTCTTCTTC AGTCCAATAA ACTGGGATGA TTTATATCAC 900

AAGAGACTCA CTCCTCCTTT CAACCCAAAT GTGGTGGGGC CGGCTGACTT AAGACACTTC 960

GATCCAGAGT TCACTAAAGA GGCAATTTCT AGCTCTATTG GACATACACC GGACTTAACA 1020

GCCAGCAGCT GTGGGGCTTC AAGTGCATTT TTAGGCTTTT CTTATGCACC TGGGGATGAG 1080

AATTTTTAA 1089

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkg++gkvllakrk+d+kfyavkvlqkk+ilkkke++himaernvllknv hp

Q: 33    FDFLKVIGKGNYGKVLLAKRKSDGKFYAVKVLQKKSILKKKEQNHIMAERNVLLKNVTHP  92

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvgl+ysfqt+eklyfvldyvnggelffhlqre++fleprarfyaae+asa+gylhsln

Q: 93    FLVGLRYSFQTSEKLYFVLDYVNGGELFFHLQREHCFLEPRARFYAAEVASAIGYLHSLN  152

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         i+yrdlkpenilld++ghvvltdfglcke++e e+ttstfcgtpeylapevlrk+pydrt

Q: 153   IIYRDLKPENILLDCQGHVVLTDFGLCKEGMEPEETTSTFCGTPEYLAPEVLRKQPYDRT  212

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyeml glppfysrdv+emy+nil+kplq+++g +vaa++ll++ll+kd+k

Q: 213   VDWWCLGAVLYEMLCGLPPFYSRDVSEMYENILHKPLQIQGGKTVAACDLLHGLLHKDQK  272

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         krlgak+dfleiknhvff

Q: 273   KRLGAKADFLEIKNHVFF  290

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG NYGKVLLAKR KSDGKFYAVK VLQKKSILKK KEQNHIMAER NVLLKNVTHP 60

FLVGLRYSFQ TSEKLYFVLD YVNGGELFFH LQREHCFLEP RARFYAAEVA SAIGYLHSLN 120

IIYRDLKPEN ILLDCQGHVV LTDFGLCKEG MEPEETTSTF CGTPEYLAPE VLRKQPYDRT 180

VDWWCLGAVL YEMLCGLPPF YSRDVSEMYE NILHKPLQIQ GGKTVAACDL LHGLLHKDQK 240

KRLGAKADFL EIKNHVFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013