EPS-MOD-00025

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MOD-00025

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	211.2	2.3E-62	863	1108	246

Status

Unreviewed

Ensembl Protein

ENSMODP00000006426

UniProt Accession

F7A1S6;

Protein Name

Protein Synonyms/Alias

Gene Name

PHLPP1

Gene Synonyms/Alias

PHLPP1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000005218	ENSMODP00000006426	ENSMODT00000006561

Organism

Monodelphis domestica

Functional Description

Protein Length

1405

Protein Sequence
(FASTA)

SRQQSPAPSA SRGPPVISFP VSSPSSSSPL SPLSSSSSSS SSSSSSSSSS SSSSSSSSSS 60

SSSSSSSSSS SSSSSSSSSS SSSSSSSSSS SPLPPPPSPS SPQFCLAEHS QRIMFPSLCL 120

TGSISRLSFQ VVPWQTACCP GRTGIFANKV PPPPPPPTLY VQFHGETTRR LEAHEKPLQI 180

QNDYLFQLGF RELWRVQEEG MDSEIGCLIR FYAGKPHSTG SSERIQLSGM YNVRKGKMQL 240

PVNRWTRRQV ILCGTCLIVS SVKDSLTGKM HVLPLIGGKV EEVKKHQHCL AFSSSGPQSQ 300

TYYICFDTFT EYLRWLRQVS KVASQRISSV DLSCCSLEHL PANLFYSQDL THLNLKQNFL 360

RQNPSSPSSR GLGELKRFTK LKSLNLSNNH LGDFPLAVCN IPTLTELNMS CNALRTVPAT 420

AGDMHNLQTF LLDGNYLQSL PAELENMQQL SYLGLSFNEF TDIPKVLEKL TAVDKLCMSG 480

NCMEILNLQT LRKMPHIKHV DLRLNVIRKL MVQEVDFLPH VTQLDLRDNK LEDLDSTVFN 540

NIEVLHCERN QLVTLNVCGY LLKALYASSN ELVQLDVYPV PNHLTFMDVS RNHLESVPEW 600

VCESRKLEVL DIGHNQIREL PARLFYNSSL RKLLVGHNQL TRLPERLERT QVEVLDVQHN 660

QLVELPPNLL MKADSLRFLN ASANKLETIP PATLSEETSS ILQELYLTNN HLTDKCVPLL 720

IGHPHLKILH MAYNRLQSFP ASKMAKLEEL EEIDISGNKL KAIPTTIMNC RRMHTVIAHS 780

NCIEVFPEVM QLTEIKCVDL SCNELSEVTL PENLPSKLQE LDLTGNPRLA LDHKTLELLN 840

NIRCFKIDQP SAGDASGAPA VWSHGYTEAS GVKNKLCVAA LSANNFCDNR EALYGVFDGD 900

RNVEVPYLLQ CTMSDILAEE LQKTKNEEEY MVNTFIVMQR KLGTAGQKLG GSAVLCHIKH 960

DPMDPGGYFT LTSANVGKCQ TVLCRNGKPL PLSKSYIMSC EEELKRIKQH KAIITEDGKV 1020

NGVTESTRIL GYTFLHPSVV PRPHVQSVTL TPQDEFFILG SKGLWDSLSI EEAVEAVRNV 1080

PDALAAAKKL CTLAQSYGCN DSISAVVVQL NVTEDSFCCC ELGAGGVPPP SPGIFPPSVN 1140

VVIKDRPPDG LGVPSSSSGM ASEISSEIST SEMSSEVGST ASDEPPPGTL SESGPGYPGE 1200

QRCMLHPVCL SSAFQRQLSS ATFSSAFSDN GLDSDDEEPI EGVFTNGSRV EVEVDIHCGQ 1260

AKEKERQRQQ PLQVPAEASD EGIVISANED EAGPPRKPDF SATGTIGRRR GNGSVAPQER 1320

SHNVIEVAAD APLRKTGGYF AAPAQPDPDD QFIIPPELEE EVKEIMKHHQ EQQQQQQQQQ 1380

QQQQQQQQHR QYQMDQLPDY YDTPL 1405

Nucleotide Sequence
(FASTA)

AGTAGACAAC AGAGCCCTGC ACCTAGTGCC AGCAGAGGCC CCCCAGTAAT CTCTTTCCCA 60

GTTAGCTCTC CTTCTTCTTC TTCTCCTCTT TCTCCTCTTT CTTCTTCTTC TTCTTCTTCT 120

TCTTCTTCTT CTTCTTCTTC TTCTTCTTCT TCTTCTTCTT CTTCTTCTTC TTCTTCTTCT 180

TCTTCTTCTT CTTCTTCTTC TTCTTCTTCT TCTTCTTCTT CTTCTTCTTC TTCTTCTTCT 240

TCTTCTTCTT CTTCTTCTTC TTCTTCTTCT TCTCCTCTTC CTCCTCCTCC TTCTCCTTCT 300

TCTCCTCAAT TCTGTCTAGC AGAACATAGT CAGAGGATCA TGTTTCCTTC ACTGTGTCTC 360

ACTGGTTCCA TTTCTCGGTT GAGCTTCCAG GTGGTCCCTT GGCAGACAGC TTGTTGTCCA 420

GGCAGGACTG GAATATTTGC AAATAAGGTT CCTCCTCCTC CTCCTCCTCC CACCCTGTAT 480

GTGCAGTTTC ACGGAGAGAC TACCCGTCGA CTGGAGGCAC ACGAGAAGCC ACTGCAGATT 540

CAAAATGACT ACCTCTTCCA ACTGGGATTT AGGGAGCTGT GGAGGGTGCA GGAGGAGGGC 600

ATGGATTCGG AGATTGGGTG CCTCATCCGC TTCTATGCAG GAAAGCCGCA CAGCACTGGT 660

AGCTCCGAAC GGATTCAGCT CTCAGGAATG TACAATGTGC GAAAAGGGAA AATGCAGCTA 720

CCAGTGAACC GATGGACAAG ACGCCAAGTT ATCCTGTGTG GAACATGCCT GATTGTGTCA 780

TCCGTGAAAG ACAGCTTGAC TGGAAAGATG CATGTCCTCC CACTAATCGG TGGAAAAGTT 840

GAAGAAGTAA AGAAGCACCA GCACTGTTTA GCCTTCAGTT CTTCTGGACC TCAAAGCCAG 900

ACCTATTACA TTTGTTTTGA TACTTTTACA GAGTACTTAA GGTGGCTTCG ACAAGTATCC 960

AAGGTTGCCT CACAGCGTAT CAGCTCAGTG GACCTTTCAT GCTGTAGCCT GGAACATCTG 1020

CCTGCCAACC TCTTCTATAG CCAAGACCTC ACTCATCTCA ATTTAAAGCA AAACTTCCTA 1080

AGGCAAAATC CCAGTTCACC ATCTAGCAGA GGACTTGGTG AACTCAAAAG GTTTACCAAG 1140

TTGAAGAGCC TTAATCTTTC CAATAACCAT CTCGGAGATT TCCCTCTGGC AGTATGCAAT 1200

ATCCCAACCT TGACCGAGCT GAACATGTCA TGCAATGCCC TCAGAACTGT TCCAGCAACA 1260

GCAGGAGATA TGCACAACTT GCAGACATTT TTGTTGGATG GTAACTATCT TCAGTCCCTT 1320

CCTGCTGAGT TGGAGAATAT GCAGCAGCTC AGTTACCTAG GACTTTCCTT CAATGAATTT 1380

ACAGACATTC CAAAGGTTTT GGAGAAACTG ACTGCTGTGG ATAAACTTTG TATGTCTGGA 1440

AACTGTATGG AAATCCTCAA CCTGCAGACT TTAAGAAAAA TGCCACACAT TAAGCATGTG 1500

GATTTAAGAT TGAATGTCAT TAGGAAACTG ATGGTGCAGG AGGTGGACTT CCTTCCTCAT 1560

GTCACTCAAC TAGACCTTCG AGACAATAAA CTTGAAGATC TGGATTCGAC AGTTTTCAAC 1620

AATATTGAAG TCCTGCATTG TGAAAGGAAC CAGTTGGTGA CACTGAATGT TTGTGGCTAT 1680

TTGCTAAAAG CACTCTATGC CTCTTCAAAT GAACTTGTGC AACTTGATGT TTACCCAGTT 1740

CCAAATCATC TGACATTCAT GGATGTTTCT AGAAACCATC TAGAAAGTGT ACCTGAGTGG 1800

GTATGTGAGA GTCGCAAGCT GGAAGTGTTG GACATTGGTC ATAACCAGAT CCGTGAGCTC 1860

CCTGCACGCC TGTTTTATAA TAGTAGTCTT CGTAAACTGC TGGTAGGGCA TAACCAGCTA 1920

ACCAGGCTCC CAGAAAGACT AGAAAGAACC CAGGTGGAGG TCCTGGATGT TCAGCACAAT 1980

CAGCTTGTTG AGCTACCACC TAATCTCCTG ATGAAGGCTG ACAGCTTGAG GTTCCTAAAT 2040

GCATCTGCCA ACAAGCTGGA AACTATTCCT CCAGCCACAC TTTCAGAAGA GACAAGCAGC 2100

ATCTTGCAGG AGCTGTACTT GACTAACAAC CACCTCACTG ACAAATGTGT GCCCTTGTTA 2160

ATAGGACACC CTCACTTGAA GATTCTACAT ATGGCCTATA ATCGGCTTCA GAGCTTTCCA 2220

GCAAGTAAAA TGGCCAAACT AGAGGAGCTA GAGGAAATAG ATATCAGTGG GAACAAACTG 2280

AAAGCCATTC CAACTACCAT CATGAACTGC CGGCGGATGC ACACTGTAAT TGCTCACTCA 2340

AATTGTATTG AGGTCTTTCC TGAAGTCATG CAGCTAACAG AAATCAAGTG TGTGGACCTG 2400

AGCTGTAATG AGCTGAGTGA AGTCACGTTA CCAGAAAATC TGCCTTCAAA GTTACAAGAA 2460

CTAGACCTGA CTGGAAACCC TCGACTTGCC CTGGATCACA AAACCCTGGA GCTGTTGAAT 2520

AATATCCGAT GTTTTAAAAT CGATCAGCCT TCTGCTGGTG ATGCTTCAGG AGCCCCAGCT 2580

GTGTGGAGCC ATGGCTACAC AGAAGCCTCC GGTGTAAAGA ATAAGTTGTG CGTTGCAGCC 2640

CTGTCAGCAA ATAACTTCTG TGACAACCGA GAAGCTTTGT ATGGAGTCTT TGATGGTGAC 2700

CGCAATGTCG AGGTGCCGTA CCTCCTCCAG TGCACCATGA GTGACATTCT GGCAGAAGAG 2760

CTACAGAAAA CAAAAAATGA AGAAGAGTAT ATGGTCAACA CCTTCATCGT CATGCAGAGG 2820

AAACTGGGAA CTGCTGGGCA AAAACTTGGA GGCTCTGCCG TCCTGTGCCA TATAAAACAT 2880

GATCCTATGG ACCCAGGAGG ATATTTTACC CTGACCTCTG CGAACGTGGG CAAGTGCCAA 2940

ACAGTTCTGT GCCGGAATGG GAAGCCTCTG CCTCTGTCGA AGTCATACAT CATGAGCTGC 3000

GAGGAGGAGC TGAAGAGAAT CAAGCAGCAC AAAGCCATCA TCACCGAGGA CGGCAAGGTG 3060

AATGGAGTGA CCGAGTCCAC CCGGATTTTG GGCTACACCT TTCTTCACCC CAGCGTGGTT 3120

CCCCGTCCCC ACGTGCAGTC GGTGACGCTG ACCCCGCAGG ACGAGTTCTT CATCTTGGGC 3180

AGCAAAGGGC TGTGGGACAG CCTGTCCATT GAAGAGGCGG TGGAGGCTGT GCGGAACGTG 3240

CCGGACGCCC TGGCCGCGGC CAAGAAGCTG TGCACCCTGG CCCAGAGCTA CGGCTGCAAC 3300

GACAGCATCA GCGCCGTGGT GGTGCAGCTC AACGTCACCG AGGACAGCTT CTGCTGCTGC 3360

GAGCTGGGGG CCGGCGGCGT GCCCCCGCCG AGCCCCGGCA TCTTCCCTCC TTCCGTCAAT 3420

GTGGTGATCA AGGACCGGCC CCCCGACGGG CTCGGGGTGC CCTCGTCCAG CAGCGGCATG 3480

GCCTCCGAGA TCAGCAGCGA GATCTCCACG TCCGAGATGA GCAGCGAGGT GGGCTCCACA 3540

GCCTCGGACG AGCCCCCGCC GGGGACGCTG AGCGAGAGCG GCCCCGGCTA CCCCGGCGAG 3600

CAGCGCTGCA TGCTGCACCC CGTGTGCCTG TCGAGCGCCT TCCAGCGCCA GCTCTCCAGC 3660

GCCACCTTCT CCAGTGCCTT CTCCGACAAC GGCCTCGACA GTGACGACGA GGAGCCCATT 3720

GAGGGCGTCT TCACCAATGG CAGCAGGGTG GAGGTGGAGG TGGACATTCA CTGTGGCCAG 3780

GCCAAGGAGA AAGAGAGGCA GCGGCAGCAG CCGCTCCAGG TGCCGGCCGA GGCCAGCGAC 3840

GAGGGCATCG TGATCAGTGC CAACGAGGAC GAGGCGGGCC CGCCCAGGAA GCCCGACTTC 3900

TCCGCCACCG GGACCATCGG GCGCAGGAGG GGCAACGGCT CCGTGGCGCC CCAGGAGCGG 3960

AGCCACAACG TGATCGAGGT GGCTGCCGAC GCGCCCCTCC GCAAGACGGG CGGCTACTTT 4020

GCCGCCCCGG CCCAGCCCGA CCCCGACGAC CAGTTCATCA TCCCGCCGGA GCTGGAAGAG 4080

GAGGTCAAAG AAATCATGAA GCACCACCAG GAGCAGCAGC AGCAGCAGCA GCAGCAGCAG 4140

CAGCAGCAGC AGCAGCAGCA GCAGCACAGG CAGTATCAGA TGGACCAGCT GCCAGACTAT 4200

TATGATACAC CACTA 4215

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g+++ +g +n+++ a+ s++nf++++e+     ++gv+DG+++ ev + +++++++il

Q: 863   SHGYTEASGVKNKLCVAALSANNFCDNREA-----LYGVFDGDRNVEVPYLLQCTMSDIL  917

         689***********************9885.....9************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

         aeel+    ++++ ++++ ++F+ ++++l       ++ +k G +av+++ik++

Q: 918   AEELQ----KTKNEEEYMVNTFIVMQRKL------GTAGQKLGGSAVLCHIKHDpmdpgg  967

         ***99....999*****************......99***********************

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLa  173

           +l+ anvG++++vLcrngk+++ls+ + +s+e+El+Ri+++++ ++++   +v+Gv++

Q: 968   yfTLTSANVGKCQTVLCRNGKPLPLSKSYIMSCEEELKRIKQHKAIITEDG--KVNGVTE  1025

         ********************************************9999998..*******

S: 174   vsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

          +R lG ++l+p v+p+P+v+s++lt++def+iL+s+Glwd +s eeav++vr+v +

Q: 1026  STRILGYTFLHPSVVPRPHVQSVTLTPQDEFFILGSKGLWDSLSIEEAVEAVRNVPD---  1082

         *********************************************************...

S: 234   aeqeaakkLvklalargskdnvsaivv  260

          + +aakkL++la+++g++d++sa+vv

Q: 1083  -ALAAAKKLCTLAQSYGCNDSISAVVV  1108

         .************************97

Domain Sequence
(FASTA)

SHGYTEASGV KNKLCVAALS ANNFCDNREA LYGVFDGDRN VEVPYLLQCT MSDILAEELQ 60

KTKNEEEYMV NTFIVMQRKL GTAGQKLGGS AVLCHIKHDP MDPGGYFTLT SANVGKCQTV 120

LCRNGKPLPL SKSYIMSCEE ELKRIKQHKA IITEDGKVNG VTESTRILGY TFLHPSVVPR 180

PHVQSVTLTP QDEFFILGSK GLWDSLSIEE AVEAVRNVPD ALAAAKKLCT LAQSYGCNDS 240

ISAVVV 246

Keyword

Complete proteome; Leucine-rich repeat; Reference proteome; Repeat.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>