EKS-MOD-00226

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00226

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
STE/STE7	384.8	2.2E-115	53	314	262

Status

Unreviewed

Ensembl Protein

ENSMODP00000007853

UniProt Accession

F7AGV5;

Protein Name

Protein Synonyms/Alias

Gene Name

MAP2K6

Gene Synonyms/Alias

MAP2K6;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000006330	ENSMODP00000007853	ENSMODT00000008012

Organism

Monodelphis domestica

Functional Description

Protein Length

334

Protein Sequence
(FASTA)

MSQPKGRKRN PGLKIPKEAF EQPQTSSAPP RDLDSKACIS IGDKNFEVKA DDLEPIAELG 60

RGAYGVVEKM RHMPSGQIMA VKRIRATVNS QEQKRLLMDL DISMRTVDCP FTVTFYGALF 120

REGDVWICME LMDTSLDKFY KQVIDKGLTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV 180

KPSNVLINTL GQVKMCDFGI SGYLVDSVAK TMDAGCKPYM APERINPELN QKGYNVKSDI 240

WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSAEFVDF TSQCLKKNSK 300

ERPTYAELMQ HQFFTLHESK ATDAASFVKL ILGD 334

Nucleotide Sequence
(FASTA)

ATGTCTCAGC CAAAAGGCAG GAAGCGGAAC CCTGGGTTGA AGATTCCAAA GGAAGCATTT 60

GAACAACCTC AGACCAGCTC AGCACCTCCT CGGGATTTAG ATTCCAAGGC TTGCATCTCA 120

ATTGGAGATA AGAATTTTGA AGTGAAGGCT GATGACTTGG AGCCTATAGC AGAACTGGGA 180

CGAGGTGCAT ATGGGGTGGT GGAGAAGATG CGACACATGC CTAGTGGGCA GATCATGGCA 240

GTGAAGCGAA TCCGAGCAAC TGTGAATAGC CAGGAACAGA AGAGGCTACT GATGGACCTG 300

GATATCTCCA TGAGGACAGT GGATTGCCCT TTCACAGTCA CCTTTTATGG TGCACTCTTT 360

CGGGAGGGTG ATGTGTGGAT CTGTATGGAA CTCATGGATA CCTCACTGGA TAAGTTCTAC 420

AAACAAGTCA TTGATAAGGG TTTAACAATC CCAGAGGACA TCTTAGGGAA AATTGCAGTT 480

TCTATTGTAA AAGCCCTAGA ACATTTACAC AGTAAACTTT CTGTCATTCA TCGAGATGTG 540

AAGCCATCTA ATGTATTGAT CAATACACTG GGTCAAGTGA AGATGTGTGA TTTTGGTATT 600

AGTGGTTACC TGGTGGACTC TGTGGCCAAA ACTATGGATG CAGGATGTAA ACCCTACATG 660

GCTCCTGAAA GAATAAATCC AGAACTAAAT CAGAAGGGGT ACAATGTGAA ATCTGACATT 720

TGGAGCCTGG GCATCACAAT GATTGAACTG GCAATCCTTA GGTTCCCCTA TGATTCCTGG 780

GGGACACCAT TTCAGCAGCT CAAGCAGGTG GTGGAAGAAC CATCACCTCA ACTTCCAGCA 840

GACAAGTTCT CAGCAGAGTT TGTCGACTTT ACCTCACAGT GCTTGAAGAA GAATTCCAAA 900

GAACGGCCAA CATATGCAGA ACTTATGCAA CATCAGTTTT TCACTCTGCA TGAATCCAAA 960

GCAACAGATG CAGCATCTTT TGTAAAACTG ATTCTTGGAG ACTAA 1005

Domain Profile

S: 1     lekleelGaGnggvVekvlhkksgkilavKtirleikkeeqkqilrelevlkkssnspyi  60

         le + elG+G++gvVek++h +sg+i+avK+ir++++++eqk++l++l++ +++ ++p++

Q: 53    LEPIAELGRGAYGVVEKMRHMPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFT  112

         57789*******************************************************

S: 61    vkfyGafvsegdvsicmelmdgtsldkvlkkvlekkkripekvlgkiavavvkaleylke  120

         v+fyGa+++egdv+icmelmd tsldk++k+v++k  +ipe++lgkiav++vkale+l++

Q: 113   VTFYGALFREGDVWICMELMD-TSLDKFYKQVIDKGLTIPEDILGKIAVSIVKALEHLHS  171

         *********************.**************************************

S: 121   klkiiHRDvKPsNiLvnskGevKlCDFGvsgqlvdsiAksa.vGtksYmaPErieg...k  176

         kl++iHRDvKPsN+L+n+ G+vK+CDFG+sg+lvds+Ak++ +G+k+YmaPEri++   +

Q: 172   KLSVIHRDVKPSNVLINTLGQVKMCDFGISGYLVDSVAKTMdAGCKPYMAPERINPelnQ  231

         ********************************************************9999

S: 177   kkYsvksdvWslGltlvelatgrypyeklkeilellkaivneeppklpeeefseefqefv  236

         k Y+vksd+WslG+t++ela+ r+py+++ +++++lk++v+e++p+lp+++fs ef++f

Q: 232   KGYNVKSDIWSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFT  291

         9***********************************************************

S: 237   skClkkdekeRpklkellkhafi  259

         s+Clkk++keRp++ el++h+f+

Q: 292   SQCLKKNSKERPTYAELMQHQFF  314

         *********************96

Domain Sequence
(FASTA)

LEPIAELGRG AYGVVEKMRH MPSGQIMAVK RIRATVNSQE QKRLLMDLDI SMRTVDCPFT 60

VTFYGALFRE GDVWICMELM DTSLDKFYKQ VIDKGLTIPE DILGKIAVSI VKALEHLHSK 120

LSVIHRDVKP SNVLINTLGQ VKMCDFGISG YLVDSVAKTM DAGCKPYMAP ERINPELNQK 180

GYNVKSDIWS LGITMIELAI LRFPYDSWGT PFQQLKQVVE EPSPQLPADK FSAEFVDFTS 240

QCLKKNSKER PTYAELMQHQ FF 262

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013