EKS-MOD-00017

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00017

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/PHK	520.3	1.1E-156	20	287	268

Status

Unreviewed

Ensembl Protein

ENSMODP00000008526

UniProt Accession

F6PWC7;

Protein Name

Protein Synonyms/Alias

Gene Name

PHKG1

Gene Synonyms/Alias

PHKG1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000006880	ENSMODP00000008526	ENSMODT00000008694

Organism

Monodelphis domestica

Functional Description

Protein Length

387

Protein Sequence
(FASTA)

MTRDEGLPDS HSAQGFYEKY EPKEILGRGV SSVVRRCIHK PTSKEYAVKI IDITAGNLNP 60

EEIQELREAT IKEIDILRKV SGHPNVIQLK DTYETNTFFF LVFDLMKKGE LFDYLTEKVT 120

LSEKETRKIM RALLEVICYL HQLDIVHRDL KPENILLDDD MNIKLTDFGF SCQLNPGEKL 180

REVCGTPSYL APEILECSMN DSHPGYGKEV DMWSTGVIMY TLLAGSPPFW HRKQMLMLRM 240

IMSGNYQFGS PEWDDRSDTV KDLISRLLVL SPQQRCTAEE ALAHPFFQQY VVQEVRHFSP 300

RGKFKVIALT VLASVRVYYQ YRRMKPVTRE IVLRDPYALR PLRKLIDACA FRIYGHWVKK 360

GQQQNRAALF ENTPKAVLLS LAEEEGF 387

Nucleotide Sequence
(FASTA)

ATGACCCGAG ATGAAGGGCT GCCAGACTCA CACTCTGCCC AGGGTTTCTA TGAGAAATAT 60

GAACCCAAGG AGATCCTGGG GAGGGGTGTG AGCAGCGTTG TGAGACGCTG TATCCACAAG 120

CCCACCAGTA AGGAGTATGC GGTGAAGATT ATTGATATCA CTGCTGGCAA CCTAAATCCT 180

GAGGAGATCC AGGAACTGCG GGAAGCCACC ATCAAGGAGA TTGACATCTT GCGCAAGGTC 240

TCCGGGCATC CCAACGTCAT CCAGCTGAAG GACACTTATG AGACCAACAC TTTCTTCTTC 300

CTGGTGTTTG ACCTGATGAA GAAAGGCGAG CTCTTTGACT ACCTCACTGA AAAAGTCACC 360

TTGAGTGAGA AAGAAACCAG GAAGATCATG CGAGCCCTAC TAGAGGTTAT CTGCTACCTG 420

CACCAGCTGG ACATTGTACA CCGAGACCTG AAGCCAGAAA ACATTCTCCT AGATGACGAC 480

ATGAATATCA AACTCACTGA CTTTGGCTTC TCCTGCCAGC TGAACCCTGG AGAGAAGCTT 540

CGAGAGGTGT GTGGGACTCC AAGTTACTTG GCTCCCGAGA TCCTTGAGTG CTCCATGAAT 600

GACAGCCACC CTGGTTATGG GAAAGAAGTA GACATGTGGA GCACAGGTGT GATCATGTAT 660

ACCCTCCTGG CTGGCTCTCC CCCTTTCTGG CACCGGAAGC AGATGCTGAT GTTGAGAATG 720

ATCATGAGTG GCAACTACCA GTTTGGTTCC CCAGAATGGG ATGACCGATC AGACACTGTC 780

AAGGACCTTA TTTCTCGCCT CCTGGTCCTG AGCCCACAGC AACGGTGCAC AGCTGAGGAA 840

GCCCTGGCCC ACCCCTTTTT CCAGCAATAT GTGGTCCAGG AAGTCCGTCA CTTCAGCCCC 900

AGGGGCAAGT TCAAGGTGAT TGCCTTGACT GTGCTCGCCT CTGTCCGAGT CTACTACCAA 960

TACCGGCGCA TGAAGCCAGT GACTCGAGAA ATTGTACTCC GAGATCCCTA TGCACTGAGA 1020

CCACTGAGGA AACTCATTGA TGCCTGTGCC TTCCGTATCT ATGGCCACTG GGTGAAGAAA 1080

GGCCAGCAAC AGAACCGGGC TGCACTCTTC GAAAACACTC CCAAGGCTGT GCTCCTCTCC 1140

CTGGCTGAGG AAGAAGGCTT CTGA 1164

Domain Profile

S: 1     yepkeilGrGvssvvrrciekatgqefavkiidvsaeklseeevkelreatlkeveilrq  60

         yepkeilGrGvssvvrrci+k+t++e+avkiid++a++l++ee++elreat+ke++ilr+

Q: 20    YEPKEILGRGVSSVVRRCIHKPTSKEYAVKIIDITAGNLNPEEIQELREATIKEIDILRK  79

         9***********************************************************

S: 61    vsGhpsiiklkdvyesssflflvfdlmkkGelfdyltekvtlseketrkimralleavey  120

         vsGhp++i+lkd+ye+++f+flvfdlmkkGelfdyltekvtlseketrkimralle+++y

Q: 80    VSGHPNVIQLKDTYETNTFFFLVFDLMKKGELFDYLTEKVTLSEKETRKIMRALLEVICY  139

         ************************************************************

S: 121   lhaknivhrdlkpenillddneniklsdfGfstqleeGeklrelcGtpgylapeilkcsm  180

         lh+ +ivhrdlkpenilldd++nikl+dfGfs+ql++Geklre+cGtp+ylapeil+csm

Q: 140   LHQLDIVHRDLKPENILLDDDMNIKLTDFGFSCQLNPGEKLREVCGTPSYLAPEILECSM  199

         ************************************************************

S: 181   deeapGyskevdlwalGvilytllaGsppfwhrkqllmlrlimeGkyqftspewddisee  240

         ++++pGy+kevd+w++Gvi+ytllaGsppfwhrkq+lmlr+im+G+yqf+spewdd+s++

Q: 200   NDSHPGYGKEVDMWSTGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDRSDT  259

         ************************************************************

S: 241   vkdliskllvvdpekrltaeealahpff  268

         vkdlis+llv+ p++r+taeealahpff

Q: 260   VKDLISRLLVLSPQQRCTAEEALAHPFF  287

         ***************************8

Domain Sequence
(FASTA)

YEPKEILGRG VSSVVRRCIH KPTSKEYAVK IIDITAGNLN PEEIQELREA TIKEIDILRK 60

VSGHPNVIQL KDTYETNTFF FLVFDLMKKG ELFDYLTEKV TLSEKETRKI MRALLEVICY 120

LHQLDIVHRD LKPENILLDD DMNIKLTDFG FSCQLNPGEK LREVCGTPSY LAPEILECSM 180

NDSHPGYGKE VDMWSTGVIM YTLLAGSPPF WHRKQMLMLR MIMSGNYQFG SPEWDDRSDT 240

VKDLISRLLV LSPQQRCTAE EALAHPFF 268

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005964	; C:phosphorylase kinase complex
GO:0005524	; F:ATP binding
GO:0004689	; F:phosphorylase kinase activity
GO:0005978	; P:glycogen biosynthetic process

KEGG

mdo:100013442

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR002291	; Phosph_kin_gamma.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

PR01049

; PHOSPHBKNASE.

Created Date

20-Feb-2013