EKS-MOD-00418

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00418

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/SGK	534.4	6.0E-161	156	413	258

Status

Unreviewed

Ensembl Protein

ENSMODP00000009855

UniProt Accession

F7GIB9;

Protein Name

Protein Synonyms/Alias

Gene Name

SGK3

Gene Synonyms/Alias

SGK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000007920	ENSMODP00000009855	ENSMODT00000010047

Organism

Monodelphis domestica

Functional Description

Protein Length

490

Protein Sequence
(FASTA)

MDCKESCPSV SIPSSDEHRE KKKRFTVYKV LVSVGRNEWF VFRRYAEFDK LYNTLKKQFP 60

TMTMKIPAKR IFGDNFDPDF IKQRRAGLNE FIQNLVRHPD LCNHPDVRAF LQMDSPRHQS 120

DPSEDEDERS IQKLHSTSQN INLGPSGNPH AKPTDFDFLK VIGKGSFGKV LLAKRKLDGK 180

FYAVKVLQKK IVLKRKEQKH IMAERNVLLK NVKHPFLVGL HYSFQTTEKL YFVLDFVNGG 240

ELFFHLQRER SFPEHRARFY AAEIASALGY LHSIKIVYRD LKPENILLDS IGHVVLTDFG 300

LCKEGIAISD TTTTFCGTPE YLAPEVIRKQ PYDNTVDWWC LGAVLYEMLY GLPPFYCRDV 360

AEMYENILHK PLNLRPGVSL TAWSILEELL EKDRQNRLGA KEDFLEIQNH PFFESINWTD 420

LVQKKIPPPF NPNVVGPDDI RNFDAAFTEE MVPYSVCISS DYSIVNASVL EADDAFVGFS 480

YAPPSEDLFL 490

Nucleotide Sequence
(FASTA)

ATGGACTGCA AAGAAAGCTG CCCAAGTGTT AGCATCCCGA GCTCTGATGA ACACAGGGAG 60

AAAAAAAAGA GGTTCACTGT TTATAAAGTA TTAGTTTCAG TTGGAAGGAA TGAATGGTTT 120

GTCTTCAGGA GATATGCTGA ATTTGATAAG CTTTATAACA CACTAAAGAA ACAGTTTCCT 180

ACTATGACAA TGAAGATTCC TGCCAAAAGA ATATTTGGTG ATAATTTTGA TCCAGATTTT 240

ATTAAACAGA GAAGAGCAGG ACTGAATGAA TTCATTCAGA ATTTAGTTAG ACATCCAGAT 300

CTATGCAACC ATCCAGATGT CAGAGCATTT CTTCAAATGG ACAGCCCAAG ACATCAGTCA 360

GATCCTTCTG AAGATGAAGA TGAAAGAAGT ATTCAGAAGC TACACTCTAC CTCACAGAAC 420

ATCAACCTGG GACCATCTGG AAATCCTCAT GCCAAACCAA CAGATTTTGA TTTCCTTAAA 480

GTTATTGGAA AAGGCAGCTT TGGTAAAGTT CTTCTTGCAA AAAGGAAACT AGATGGAAAA 540

TTTTATGCTG TCAAAGTGTT GCAGAAAAAA ATTGTTCTGA AGAGGAAGGA GCAAAAACAT 600

ATTATGGCTG AACGTAATGT GCTCTTGAAA AATGTGAAGC ATCCATTTTT GGTTGGATTA 660

CATTATTCAT TCCAGACAAC TGAAAAGCTT TATTTTGTTC TGGATTTTGT AAATGGAGGG 720

GAGCTATTCT TTCATTTACA AAGAGAACGG TCCTTTCCAG AACACAGAGC CAGATTTTAT 780

GCTGCAGAAA TTGCCAGTGC TTTGGGCTAC TTGCATTCCA TAAAAATAGT ATACAGAGAC 840

TTGAAACCAG AAAACATTCT TTTGGACTCA ATAGGACATG TTGTTTTAAC AGATTTTGGG 900

TTATGTAAAG AAGGGATCGC TATATCTGAC ACAACTACAA CGTTTTGTGG GACACCAGAG 960

TACCTTGCAC CAGAAGTGAT TAGAAAACAG CCTTATGACA ATACTGTAGA TTGGTGGTGC 1020

CTTGGTGCTG TTCTCTATGA AATGCTGTAT GGGTTGCCTC CATTTTACTG CCGGGATGTT 1080

GCTGAGATGT ATGAAAACAT ACTCCATAAA CCTTTAAATT TGAGGCCAGG AGTGAGCCTC 1140

ACTGCCTGGT CCATTCTGGA AGAACTTCTG GAAAAAGACA GACAAAATCG ACTTGGTGCC 1200

AAAGAAGACT TTCTTGAAAT TCAAAATCAT CCTTTCTTCG AATCAATCAA CTGGACTGAC 1260

CTTGTTCAAA AGAAGATTCC ACCACCCTTT AATCCTAATG TGGTTGGACC AGATGATATC 1320

AGGAACTTTG ATGCAGCCTT TACGGAAGAA ATGGTTCCGT ATTCTGTTTG TATATCTTCT 1380

GACTATTCCA TAGTGAATGC CAGTGTTTTG GAGGCAGATG ATGCATTCGT CGGTTTCTCT 1440

TATGCACCTC CTTCTGAAGA TTTGTTTTTG TAA 1473

Domain Profile

S: 1     fdflkvigkgsfgkvllakrkadekfyavkvlqkkailkkkeekhimaernvllknvkhp  60

         fdflkvigkgsfgkvllakrk d+kfyavkvlqkk++lk+ke+khimaernvllknvkhp

Q: 156   FDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLKRKEQKHIMAERNVLLKNVKHP  215

         9***********************************************************

S: 61    flvglhysfqtaeklyfvldyvnggelffhlqrersfleprarfyaaeiasalgylhsln  120

         flvglhysfqt+eklyfvld+vnggelffhlqrersf+e+rarfyaaeiasalgylhs++

Q: 216   FLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIK  275

         ************************************************************

S: 121   ivyrdlkpenilldskghvvltdfglckeeieaedttstfcgtpeylapevlrkkpydrt  180

         ivyrdlkpenillds ghvvltdfglcke+i+++dtt+tfcgtpeylapev+rk+pyd+t

Q: 276   IVYRDLKPENILLDSIGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNT  335

         ************************************************************

S: 181   vdwwclgavlyemlyglppfysrdvaemydnilnkplqlkpgisvaalelleellekdrk  240

         vdwwclgavlyemlyglppfy+rdvaemy+nil+kpl+l+pg+s++a+++leellekdr+

Q: 336   VDWWCLGAVLYEMLYGLPPFYCRDVAEMYENILHKPLNLRPGVSLTAWSILEELLEKDRQ  395

         ************************************************************

S: 241   krlgakedfleiknhvff  258

         +rlgakedflei+nh+ff

Q: 396   NRLGAKEDFLEIQNHPFF  413

         *****************9

Domain Sequence
(FASTA)

FDFLKVIGKG SFGKVLLAKR KLDGKFYAVK VLQKKIVLKR KEQKHIMAER NVLLKNVKHP 60

FLVGLHYSFQ TTEKLYFVLD FVNGGELFFH LQRERSFPEH RARFYAAEIA SALGYLHSIK 120

IVYRDLKPEN ILLDSIGHVV LTDFGLCKEG IAISDTTTTF CGTPEYLAPE VIRKQPYDNT 180

VDWWCLGAVL YEMLYGLPPF YCRDVAEMYE NILHKPLNLR PGVSLTAWSI LEELLEKDRQ 240

NRLGAKEDFL EIQNHPFF 258

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0016023	; C:cytoplasmic membrane-bounded vesicle
GO:0005524	; F:ATP binding
GO:0035091	; F:phosphatidylinositol binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007154	; P:cell communication

KEGG

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR001683	; Phox.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.
PF00787	; PX; 1.

SMARTs

SM00312	; PX; 1.
SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.
PS50195	; PX; 1.

Prints

Created Date

20-Feb-2013