EKS-MOD-00282

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00282

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/IRE	442.6	5.4E-133	580	824	245

Status

Unreviewed

Ensembl Protein

ENSMODP00000011681

UniProt Accession

F7G0C7;

Protein Name

Protein Synonyms/Alias

Gene Name

ERN1

Gene Synonyms/Alias

ERN1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000009349	ENSMODP00000011681	ENSMODT00000011901

Organism

Monodelphis domestica

Functional Description

Protein Length

969

Protein Sequence
(FASTA)

MPVPPRRLLQ LLALLLLPLP GPGSFASTST VTLPETLLFV STLDGSLHAV SKRTGSTKWT 60

LKEDPVLQVP THVEEPAFLP DPNDGSLYTL GGKNNEGLTK LPFTIPELVQ ASPCRSSDGI 120

LYMGKKQDIW YVVDLMTGEK QQTLSSAFAE SLCPSTSLLY LGRTEYTITM FDTKSRELRW 180

NATYFDYAAT VPEEDVEYKM SHFVSNGDGL VVTVDSESGD VLWIQNYASP VVAFYIWHRE 240

GLQKVMHTNV GVETLRYLTF MSGEVGRITK WKYPFPKETE TKSKLTPTLY VGRYSTSLYA 300

SPSMVHEGVA IVPRGSAFPQ LEGPQTDGVT IKSNEECVIT PSVEFGFGFK GKNKLNYWTN 360

YWLLIGHHEI PLSASTTVLE KFPNKLPRHP ENVIPADSEK SFDEVIKMVD RHTEEPTPTT 420

RQDIEFTRTP VKTEAAVDSM LKDMATIILC TFLLIGWVAF VITYPMSPIS FSALYIEWKC 480

TCIELLPVGP LCAFQNYSYF HPPSDLSQDS DFLDVSAGLH SESSAPSSPN MSPKGSNHSQ 540

HSSNSAFKVS SIVAAEQDEN GKAMCYFLRA NLIPFYPFSR GTFDNRAVAV KRILPECFSF 600

ADREVQLLRE SDEHPNVIRY FCTERDRQFQ YIAIELCAAT LQEYVEQKDF AHLGLEPITL 660

LQQTTSGLAY LHSLSIVHRD LKPHNILLSM PNAHGKIKAM ISDFGLCKKL AVGRHSFSRR 720

SGVPGTEGWI APEMLSEDCK ENPTYTVDIF SAGCVFYYVI SDGNHPFGKS LQRQANILLG 780

AYSLDCLHPE KHEDIVAHEL IEKMIAMDPQ KRPSAKHVLK HPFFWGLEKQ LQFFQDVSDR 840

IEKEALDGPI VKQLERGGRA VVKMDWRENI TVPLQTDLRK FRTYKGGSVR DLLRAMRNKK 900

HHYRELPEAV QETLGSIPDD FVRYFTSRFP HLLSHTYRAM ELCSHERLFQ PYYFQEATEL 960

GPLVTNDGL 969

Nucleotide Sequence
(FASTA)

ATGCCGGTCC CGCCGCGCCG GCTCCTGCAG CTGCTGGCGC TGCTGCTCTT GCCCCTGCCG 60

GGTCCCGGGA GTTTTGCAAG CACCAGCACT GTGACCCTTC CTGAGACCCT GTTGTTTGTT 120

TCAACCTTGG ATGGAAGCCT GCATGCCGTG AGCAAGAGGA CGGGATCAAC AAAATGGACT 180

TTAAAAGAAG ATCCAGTCCT GCAGGTCCCC ACCCATGTTG AAGAGCCTGC TTTCCTACCA 240

GACCCCAATG ATGGAAGCCT GTACACACTT GGTGGGAAGA ACAATGAAGG TCTGACGAAA 300

CTTCCCTTTA CCATTCCAGA ATTGGTGCAG GCATCCCCGT GTCGAAGTTC AGATGGGATT 360

CTCTACATGG GTAAAAAGCA GGATATTTGG TATGTCGTCG ACCTCATGAC TGGGGAGAAG 420

CAGCAGACTT TATCTTCAGC ATTTGCAGAA AGCCTCTGTC CATCCACCTC TCTTCTGTAT 480

CTTGGACGTA CAGAGTACAC CATCACCATG TTTGATACAA AGAGTCGAGA GCTTCGGTGG 540

AATGCTACCT ATTTTGACTA CGCAGCCACT GTACCAGAGG AGGATGTGGA ATACAAGATG 600

TCCCACTTTG TGTCCAATGG GGATGGGCTG GTGGTGACTG TGGACAGTGA GTCTGGCGAT 660

GTCTTGTGGA TTCAGAATTA TGCCTCGCCA GTGGTGGCCT TCTACATCTG GCATCGAGAA 720

GGCCTGCAGA AGGTGATGCA CACCAATGTC GGGGTGGAGA CACTGCGCTA TCTGACCTTC 780

ATGTCTGGAG AGGTGGGACG GATCACCAAG TGGAAATACC CCTTCCCAAA GGAGACCGAG 840

ACCAAGAGCA AACTGACGCC CACCCTCTAC GTTGGGAGGT ATTCCACCAG CCTGTATGCC 900

TCCCCATCAA TGGTACATGA AGGAGTTGCT ATTGTGCCTC GAGGTAGTGC CTTTCCCCAA 960

CTGGAAGGCC CCCAGACAGA CGGTGTCACA ATCAAAAGTA ATGAAGAGTG TGTGATCACC 1020

CCCAGCGTAG AGTTTGGTTT TGGATTCAAA GGAAAGAACA AACTCAACTA CTGGACCAAT 1080

TATTGGCTTC TCATAGGACA TCATGAGATC CCCCTGTCTG CTTCCACCAC AGTCCTGGAG 1140

AAATTCCCCA ACAAACTGCC CCGGCATCCT GAAAATGTGA TCCCTGCTGA TTCCGAAAAG 1200

AGTTTTGATG AGGTTATCAA AATGGTTGAC CGGCACACAG AAGAACCAAC TCCTACTACT 1260

CGTCAAGATA TTGAATTCAC TCGAACCCCA GTAAAAACAG AGGCTGCTGT AGACTCCATG 1320

TTGAAGGACA TGGCTACAAT CATCCTGTGT ACCTTCCTTC TCATTGGATG GGTCGCCTTC 1380

GTCATCACCT ACCCAATGTC ACCAATCAGC TTCTCTGCTC TTTATATCGA GTGGAAATGC 1440

ACCTGCATTG AACTTCTGCC TGTGGGTCCT CTCTGTGCCT TCCAAAACTA CTCCTACTTC 1500

CACCCTCCGA GTGACCTGTC TCAGGACTCG GATTTCCTGG ATGTCTCTGC TGGTTTGCAC 1560

TCCGAGAGCT CAGCCCCCAG CAGTCCCAAC ATGTCCCCCA AGGGCTCCAA CCACTCTCAG 1620

CATTCCAGCA ACTCAGCTTT CAAGGTCAGC AGCATCGTGG CTGCTGAGCA AGATGAGAAT 1680

GGTAAAGCCA TGTGTTATTT TCTACGGGCA AACCTTATAC CTTTTTACCC TTTTTCCAGA 1740

GGGACGTTTG ACAATAGAGC TGTGGCAGTG AAAAGGATAC TCCCAGAGTG CTTCAGTTTT 1800

GCAGACCGGG AGGTGCAGCT GCTTCGGGAA TCAGACGAGC ATCCCAATGT GATTCGCTAT 1860

TTCTGCACAG AGCGAGATCG TCAATTCCAA TACATTGCCA TTGAACTGTG TGCGGCCACT 1920

TTGCAAGAGT ACGTGGAACA GAAGGACTTT GCCCACCTTG GCTTAGAACC CATCACCTTG 1980

CTGCAGCAGA CAACCTCGGG TCTTGCTTAC CTTCACTCCC TCAGCATTGT TCACAGAGAC 2040

CTGAAACCCC ACAACATCCT CCTGTCCATG CCCAATGCAC ATGGCAAGAT CAAGGCTATG 2100

ATCTCTGACT TTGGCCTCTG CAAGAAGCTG GCTGTAGGAA GGCACAGTTT CAGTCGCCGC 2160

TCTGGGGTAC CAGGTACCGA GGGATGGATT GCCCCAGAGA TGCTGAGTGA AGATTGCAAA 2220

GAGAATCCGA CTTACACTGT GGACATTTTC TCTGCGGGCT GTGTCTTTTA CTATGTGATA 2280

TCTGATGGCA ACCACCCATT TGGCAAGTCC CTGCAGCGGC AAGCCAACAT CCTTCTTGGC 2340

GCCTACAGCC TTGACTGTTT GCACCCAGAG AAGCACGAAG ACATCGTTGC TCATGAACTA 2400

ATAGAAAAAA TGATTGCTAT GGATCCTCAG AAAAGGCCCT CAGCCAAGCA TGTACTGAAA 2460

CACCCATTCT TCTGGGGCTT AGAAAAGCAG CTGCAATTCT TTCAGGATGT GAGTGACCGA 2520

ATAGAGAAGG AGGCCCTAGA TGGCCCCATA GTGAAGCAGT TAGAAAGAGG AGGGAGAGCG 2580

GTGGTCAAAA TGGACTGGAG GGAAAACATA ACTGTTCCAC TCCAGACAGA TCTTCGAAAA 2640

TTCAGGACCT ATAAAGGGGG TTCTGTAAGA GATCTTCTCC GTGCTATGAG AAATAAGAAG 2700

CACCACTACC GGGAGCTTCC GGAGGCTGTG CAGGAGACCC TGGGCTCTAT CCCTGATGAT 2760

TTTGTCCGTT ATTTCACATC ACGGTTCCCC CATCTCCTCT CCCACACCTA CCGAGCCATG 2820

GAACTATGTA GCCATGAGAG ACTCTTCCAG CCTTACTATT TCCAAGAGGC CACAGAACTG 2880

GGACCCCTAG TCACAAACGA CGGTCTCTGA 2910

Domain Profile

S: 18    rGsfegrevavkrllsefvdlakrevkllresdehpnviryfctekdrqfryialelcaa  77

         rG+f++r+vavkr+l+e++++a+rev+llresdehpnviryfcte+drqf+yia+elcaa

Q: 580   RGTFDNRAVAVKRILPECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAA  639

         8***********************************************************

S: 78    slqdyvedkdlelqkelepisllkqiasGlahlhslkivhrdlkpqnilislpdakgklr  137

         +lq+yve+kd++ + +lepi+ll+q++sGla+lhsl+ivhrdlkp+nil+s+p+a+gk++

Q: 640   TLQEYVEQKDFA-HLGLEPITLLQQTTSGLAYLHSLSIVHRDLKPHNILLSMPNAHGKIK  698

         ************.***********************************************

S: 138   vlisdfGlckkldvGkssfsrrsgvsGteGwiapelleeltkerltsavdifslGcvfyy  197

         ++isdfGlckkl+vG++sfsrrsgv+GteGwiape+l+e++ke++t++vdifs+Gcvfyy

Q: 699   AMISDFGLCKKLAVGRHSFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYY  758

         ************************************************************

S: 198   vlskGkhpfGdslkrqanilsgelsldklkeekdeeviaedliskmidkdplkrpsakkv  257

         v+s+G+hpfG+sl+rqanil g++sld+l++ek+e+++a++li+kmi++dp+krpsak+v

Q: 759   VISDGNHPFGKSLQRQANILLGAYSLDCLHPEKHEDIVAHELIEKMIAMDPQKRPSAKHV  818

         ************************************************************

S: 258   lkhplf  263

         lkhp+f

Q: 819   LKHPFF  824

         *****9

Domain Sequence
(FASTA)

RGTFDNRAVA VKRILPECFS FADREVQLLR ESDEHPNVIR YFCTERDRQF QYIAIELCAA 60

TLQEYVEQKD FAHLGLEPIT LLQQTTSGLA YLHSLSIVHR DLKPHNILLS MPNAHGKIKA 120

MISDFGLCKK LAVGRHSFSR RSGVPGTEGW IAPEMLSEDC KENPTYTVDI FSAGCVFYYV 180

ISDGNHPFGK SLQRQANILL GAYSLDCLHP EKHEDIVAHE LIEKMIAMDP QKRPSAKHVL 240

KHPFF 245

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0016891	; F:endoribonuclease activity, producing 5'-phosphomonoesters
GO:0004674	; F:protein serine/threonine kinase activity
GO:0006397	; P:mRNA processing

KEGG

InterPros

IPR010513	; KEN_RNase_activator.
IPR011009	; Kinase-like_dom.
IPR018391	; PQQ_beta_propeller_repeat.
IPR000719	; Prot_kinase_cat_dom.
IPR006567	; PUG-dom.
IPR011047	; Quinonprotein_ADH-like.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF06479	; Ribonuc_2-5A; 1.

SMARTs

SM00564	; PQQ; 5.
SM00580	; PUG; 1.

Prosites

PS51392	; KEN; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013