EKS-MOD-00069

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00069

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	330.7	7.4E-99	4	288	285

Status

Unreviewed

Ensembl Protein

ENSMODP00000012638

UniProt Accession

F6XM60;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK20

Gene Synonyms/Alias

CDK20;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000010092	ENSMODP00000012638	ENSMODT00000012868

Organism

Monodelphis domestica

Functional Description

Protein Length

346

Protein Sequence
(FASTA)

MDQYSILGRI GEGAHGIVFK AKHVETGETV ALKKVALRRL EDGIPNQALR EIKALQEIED 60

NQYVVKLKAV FPHGAGFVLA FEFMLSDLSE VIRHGKRPLA PAQVKAYMQM LLKGVAFCHA 120

NNIVHRDLKP ANLLISSSGQ LKIADFGLAR VFSHEGDRLY SHQVATRWYR APELLYGARQ 180

YGEGVDLWAV GCILGELLNG SPLFPGENDI EQLCCVLRVL GTPSPKVWPE ITELPDYNKI 240

SFKEQLPLPL DDVLPDASPP ALHLLGRFLV YPPRQRIQAD QALLHEYFFR APLPAHPSEL 300

PIPQRGGGPG PKARPGPPHV HDFRVEQPLA ESLPDPELIR PYLPEG 346

Nucleotide Sequence
(FASTA)

ATGGACCAGT ACAGCATCCT GGGCCGAATA GGCGAAGGGG CCCATGGCAT CGTCTTCAAG 60

GCCAAGCACG TGGAGACGGG GGAGACCGTG GCTCTAAAGA AGGTTGCCTT GCGGAGGCTG 120

GAGGATGGGA TCCCCAACCA GGCCCTGCGG GAGATCAAGG CTCTCCAGGA GATTGAGGAC 180

AACCAGTATG TGGTGAAGTT GAAGGCTGTG TTCCCGCATG GAGCAGGCTT CGTCCTGGCT 240

TTTGAATTTA TGCTCTCTGA CCTGTCAGAG GTCATCCGGC ATGGGAAGCG GCCTCTGGCC 300

CCAGCTCAGG TCAAGGCCTA CATGCAAATG CTACTCAAGG GGGTAGCCTT CTGCCACGCC 360

AACAACATTG TACACCGGGA CCTGAAGCCA GCCAACCTGC TTATCAGCTC CTCGGGCCAG 420

TTGAAGATAG CCGACTTCGG CCTGGCCCGT GTCTTCTCCC ATGAGGGGGA CCGACTTTAT 480

AGCCACCAGG TGGCCACTAG GTGGTATCGG GCTCCGGAGC TCCTGTATGG TGCCAGGCAG 540

TATGGCGAGG GTGTGGACCT GTGGGCTGTG GGCTGCATCC TTGGGGAGCT CCTGAATGGC 600

TCCCCTCTCT TCCCTGGTGA GAATGACATT GAACAGCTCT GCTGTGTTCT CCGGGTCCTC 660

GGGACACCTA GCCCCAAGGT GTGGCCGGAG ATCACTGAGC TCCCAGATTA CAACAAGATC 720

TCCTTCAAAG AGCAGCTGCC CCTGCCCCTG GATGATGTGT TGCCCGATGC CTCTCCCCCA 780

GCCCTGCATC TCCTTGGCCG CTTTCTTGTC TATCCCCCTC GCCAGCGGAT CCAGGCTGAT 840

CAGGCCCTGC TACATGAGTA CTTCTTCAGA GCCCCGCTGC CAGCCCACCC CTCAGAGCTG 900

CCCATTCCAC AGCGTGGGGG AGGGCCCGGC CCCAAGGCCC GACCAGGCCC CCCTCATGTC 960

CACGACTTCA GGGTAGAGCA GCCCCTGGCT GAGTCGTTGC CAGATCCGGA GCTGATTCGG 1020

CCCTACCTCC CCGAGGGATG A 1041

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkel.khkn  59

         y+ l +igeG++g v+kak+ etge+vAlKk++l + ++g+p +alrEi+ l+e+ ++++

Q: 4     YSILGRIGEGAHGIVFKAKHVETGETVALKKVALRRLEDGIPNQALREIKALQEIeDNQY  63

         778899*************************************************77899

S: 60    ivkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsn  119

         +vkL+ v+  + + ++L fef+ +dL++++++ k+  l +++vk ++++ll+g+a++H+n

Q: 64    VVKLKAVFP-HGAGFVLAFEFMLSDLSEVIRHGKR-PLAPAQVKAYMQMLLKGVAFCHAN  121

         *********.99*******************9999.************************

S: 120   kilHRDlKpqNlLiskegklklaDfGlarafssplkt.ytkevvTlwYraPelLlgakeY  178

         +i+HRDlKp+NlLis++g+lk+aDfGlar fs++ ++ y+++v T+wYraPelL+ga++Y

Q: 122   NIVHRDLKPANLLISSSGQLKIADFGLARVFSHEGDRlYSHQVATRWYRAPELLYGARQY  181

         *******************************8887755**********************

S: 179   stavDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ks  237

         ++ vD+W+vgcil ell+ +plf+g+++i+ql  ++++lgtps kvwpe+++lp+y+  s

Q: 182   GEGVDLWAVGCILGELLNGSPLFPGENDIEQLCCVLRVLGTPSPKVWPEITELPDYNkIS  241

         *********************************************************889

S: 238   fpkkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         f+++ +  l++++++++  al+ll ++l + p++Ri+a++al h+yf

Q: 242   FKEQLPLPLDDVLPDASPPALHLLGRFLVYPPRQRIQADQALLHEYF  288

         9999999***************************************9

Domain Sequence
(FASTA)

YSILGRIGEG AHGIVFKAKH VETGETVALK KVALRRLEDG IPNQALREIK ALQEIEDNQY 60

VVKLKAVFPH GAGFVLAFEF MLSDLSEVIR HGKRPLAPAQ VKAYMQMLLK GVAFCHANNI 120

VHRDLKPANL LISSSGQLKI ADFGLARVFS HEGDRLYSHQ VATRWYRAPE LLYGARQYGE 180

GVDLWAVGCI LGELLNGSPL FPGENDIEQL CCVLRVLGTP SPKVWPEITE LPDYNKISFK 240

EQLPLPLDDV LPDASPPALH LLGRFLVYPP RQRIQADQAL LHEYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

mdo:100013678

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013