EKS-MOD-00202

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00202

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	510.7	1.1E-153	4	284	281

Status

Unreviewed

Ensembl Protein

ENSMODP00000034873

UniProt Accession

F6PPR3;

Protein Name

Protein Synonyms/Alias

Gene Name

MAK

Gene Synonyms/Alias

MAK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000010363	ENSMODP00000034873	ENSMODT00000036461

Organism

Monodelphis domestica

Functional Description

Protein Length

563

Protein Sequence
(FASTA)

MNRYTTMRQL GDGTYGSVLM GKSNESGELV AIKRMKRKFY SWDECMNLRE VKSLKKLNHA 60

NVIKLKEVIR ENDHLYFVFE YMKENLYQLM KDRNKLFPES VIRNIMYQIL QGLAFIHKHG 120

FFHRDMKPEN LLCMGPELVK IADFGLAREL RSQPPYTDYV STRWYRAPEV LLRSSVYSSP 180

IDVWAVGSIM AELYTLRPLF PGTSEVDEIF KICQVLGTPR KSDWPEGYQL ASSMNFRFPQ 240

CVPINLKTLI PNASSEAIQL MGDMLNWDPK KRPTASQALK YPYFQVGQVL GPPPQYSEPK 300

QSVNKQLQPI EPKQSFVELE LKPSPDEQTQ PHPQQKISHQ PLQPIQLPQN LPSQQPSKQQ 360

LHQKHQEPLF PSIVKNSSPK HNVAVGHKNG RRRWGQTVFK TGDSWEDIDD SDFGASHSKK 420

PSISAPKEKK KKDLAFSIPE LVRSGSNQSG RENKNLPAAF FKTDPNMSSS SAAKQYYLRQ 480

SRYLPGVNPK NVSLLTSGKE GHPYTWNNSL FSKPLGPIGT GLAFNRSNAE ESIIKPIEKL 540

SCKEMLPEKI EEAKGNFGKL CYL 563

Nucleotide Sequence
(FASTA)

ATGAACCGAT ATACAACTAT GAGACAACTA GGAGATGGCA CCTATGGGAG TGTACTTATG 60

GGAAAAAGCA ATGAATCTGG AGAGCTGGTG GCTATCAAAA GGATGAAAAG GAAGTTTTAT 120

TCTTGGGATG AATGCATGAA CTTGAGAGAA GTTAAGTCAC TAAAGAAACT CAATCATGCC 180

AATGTGATTA AATTGAAAGA AGTTATCAGA GAAAATGACC ACCTTTATTT TGTGTTTGAA 240

TACATGAAGG AAAACCTCTA TCAGTTAATG AAGGACAGAA ACAAGTTGTT CCCTGAGTCA 300

GTCATCAGAA ACATTATGTA TCAGATATTA CAAGGGCTAG CTTTTATCCA TAAGCACGGA 360

TTTTTCCATA GAGATATGAA GCCAGAAAAT TTACTTTGTA TGGGTCCAGA ACTTGTGAAA 420

ATTGCTGATT TTGGTCTTGC AAGAGAATTA AGATCACAAC CACCATATAC TGATTATGTA 480

TCTACCAGGT GGTATCGTGC CCCTGAAGTT TTATTAAGAT CTTCAGTGTA TAGTTCCCCC 540

ATTGATGTGT GGGCTGTTGG GAGCATAATG GCTGAACTAT ATACATTGAG ACCACTTTTC 600

CCAGGTACAA GTGAAGTAGA TGAAATCTTC AAAATTTGCC AAGTGTTAGG GACTCCTAGA 660

AAGAGTGACT GGCCAGAAGG ATACCAGCTT GCATCCTCTA TGAATTTCCG CTTTCCACAA 720

TGTGTTCCTA TAAATTTGAA AACTCTAATT CCCAATGCAA GTAGTGAAGC TATACAACTT 780

ATGGGTGATA TGCTGAATTG GGACCCAAAA AAACGGCCAA CAGCAAGTCA GGCTTTAAAA 840

TATCCCTATT TTCAAGTTGG TCAAGTATTA GGCCCTCCTC CACAGTACTC AGAACCAAAG 900

CAATCTGTGA ATAAACAACT TCAGCCAATA GAGCCAAAAC AATCATTCGT TGAATTAGAA 960

CTAAAGCCTT CACCAGATGA GCAGACCCAG CCACATCCCC AACAAAAAAT TAGTCATCAA 1020

CCATTACAAC CAATTCAGCT GCCACAGAAC TTGCCTTCCC AGCAGCCTTC AAAACAACAG 1080

CTTCATCAAA AACATCAAGA ACCATTATTT CCAAGTATCG TTAAAAACTC ATCACCTAAG 1140

CACAATGTTG CAGTGGGTCA TAAAAATGGT AGGAGGCGTT GGGGTCAGAC TGTGTTCAAG 1200

ACTGGAGATA GCTGGGAAGA TATTGACGAC TCTGATTTTG GAGCCTCACA TTCCAAGAAG 1260

CCCAGTATAT CTGCTCCAAA AGAAAAGAAG AAAAAGGATT TGGCATTTAG TATACCTGAA 1320

CTTGTACGCT CAGGCTCCAA TCAGTCGGGA AGAGAAAATA AGAATTTGCC TGCTGCTTTC 1380

TTTAAAACTG ACCCTAATAT GTCATCCAGT TCAGCTGCCA AACAATACTA CTTGAGGCAA 1440

TCAAGGTATC TTCCAGGTGT CAATCCTAAG AATGTGTCTT TGTTGACCAG TGGAAAAGAA 1500

GGACATCCAT ATACCTGGAA TAATTCACTA TTTTCCAAAC CATTGGGGCC CATTGGTACA 1560

GGACTTGCTT TCAACAGGTC AAATGCAGAA GAAAGCATAA TTAAGCCAAT TGAAAAGCTA 1620

TCATGCAAAG AAATGTTACC TGAAAAAATA GAGGAAGCAA AAGGAAATTT TGGAAAGTTA 1680

TGCTACTTAT AA 1692

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y+++++lGdGt+g+vl++ks+++gelvaik+mkrkf+s++e++nlrevkslkkln h+n+

Q: 4     YTTMRQLGDGTYGSVLMGKSNESGELVAIKRMKRKFYSWDECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         iklkevi  rend+ly+v+e+m+enlyql+kdr+kl++es++++i+yqil+glafihkhg

Q: 63    IKLKEVI--RENDHLYFVFEYMKENLYQLMKDRNKLFPESVIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrd+kPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs+vyssp

Q: 121   FFHRDMKPENLLCMGPELVKIADFGLARELRSQPPYTDYVSTRWYRAPEVLLRSSVYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavG+++ae+++lrplfPG+se+d+ifki++vlGtP k++w+e+y+las++n++fpq

Q: 181   IDVWAVGSIMAELYTLRPLFPGTSEVDEIFKICQVLGTPRKSDWPEGYQLASSMNFRFPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lktl++nas+ea++l+ d+l++dP++r+ta+qalkypyf

Q: 241   CVPINLKTLIPNASSEAIQLMGDMLNWDPKKRPTASQALKYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTMRQLGDG TYGSVLMGKS NESGELVAIK RMKRKFYSWD ECMNLREVKS LKKLNHANVI 60

KLKEVIREND HLYFVFEYMK ENLYQLMKDR NKLFPESVIR NIMYQILQGL AFIHKHGFFH 120

RDMKPENLLC MGPELVKIAD FGLARELRSQ PPYTDYVSTR WYRAPEVLLR SSVYSSPIDV 180

WAVGSIMAEL YTLRPLFPGT SEVDEIFKIC QVLGTPRKSD WPEGYQLASS MNFRFPQCVP 240

INLKTLIPNA SSEAIQLMGD MLNWDPKKRP TASQALKYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013