EKS-MOD-00058

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00058

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	385.7	1.3E-115	159	440	282

Status

Unreviewed

Ensembl Protein

ENSMODP00000013497

UniProt Accession

F7FJW3;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK16

Gene Synonyms/Alias

CDK16;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000010767	ENSMODP00000013497	ENSMODT00000013743

Organism

Monodelphis domestica

Functional Description

Protein Length

490

Protein Sequence
(FASTA)

MDRMKKIKRQ LSMTLRGSRP ADKSSGSEQL SIEENNCSDN GEGTTKGGFP LTGPLPSSLR 60

IWIVHEDLKI GSDGESDQAS ATSSDEVQSP VRVRMRNHPA RKISTEDINK RLSLPADIRL 120

PEGYLEKLTL NSPLFDKPLS RRLRRVSLSE IGFGKLETYV KLDKLGEGTY ATVYKGKSKL 180

TDNLVALKEI RLEHEEGAPC TAIREVSLLK DLKHANIVTL HDIIHTDKSL TLVFEYLDKD 240

LKQYLEDCGN IINMYNVKLF LFQLLRGLAY CHRQKVLHRD LKPQNLLINE RGELKLADFG 300

LARAKSIPTK TYSNEVVTLW YRPPDILLGS TDYSTQIDMW GVGCIFYEMA TGRPLFPGST 360

VEEQLHFIFR ILGTPTEETW PGISSNEEFK NYDYPKYRAE ALLSHAPRLD TDGADLLAKL 420

LQFEGRNRIS ADDAMRHPFF QSLGSRIHKL PDTTSIFALK EIQLQKETGL RSASLTDSGG 480

PAFRVVDTEF 490

Nucleotide Sequence
(FASTA)

ATGGACCGCA TGAAGAAGAT CAAGCGACAG CTTTCCATGA CACTCAGGGG GAGCCGGCCT 60

GCGGACAAGA GCAGTGGCTC TGAGCAGCTC AGCATTGAGG AGAACAACTG CAGTGATAAC 120

GGTGAGGGTA CGACCAAGGG GGGGTTCCCT CTCACTGGGC CACTCCCTTC CTCCCTTCGG 180

ATTTGGATTG TGCATGAGGA CCTGAAGATC GGTTCAGATG GGGAGAGTGA CCAGGCCTCA 240

GCCACGTCCT CTGATGAAGT ACAGTCACCT GTGAGAGTCC GAATGCGAAA CCATCCAGCC 300

CGCAAGATCT CTACTGAGGA CATCAACAAG CGCCTTTCCC TCCCTGCGGA CATCCGGCTG 360

CCCGAGGGCT ACCTGGAGAA GCTGACCCTC AATAGTCCAC TCTTTGACAA GCCCTTGAGC 420

AGGCGTCTCC GCCGGGTCTC CCTGTCTGAA ATCGGCTTTG GCAAGCTGGA GACATATGTG 480

AAACTGGACA AGCTGGGGGA GGGGACCTAT GCCACTGTAT ATAAGGGGAA GAGCAAGTTA 540

ACGGATAACC TGGTGGCCCT GAAGGAGATC CGGCTGGAGC ATGAAGAGGG CGCCCCCTGC 600

ACCGCCATTC GAGAAGTGTC ACTGCTGAAG GACTTGAAAC ATGCCAACAT TGTCACCCTA 660

CACGACATTA TTCACACAGA CAAATCCCTG ACTCTAGTGT TTGAGTATCT GGACAAGGAC 720

CTAAAGCAGT ACCTGGAGGA TTGTGGGAAC ATCATCAACA TGTATAATGT CAAGCTCTTT 780

CTGTTCCAGT TGCTCAGGGG CCTGGCCTAC TGTCACCGGC AGAAGGTGCT ACACCGAGAC 840

CTCAAACCCC AGAACTTGCT GATCAATGAG CGTGGGGAGC TCAAGCTGGC CGACTTTGGC 900

CTGGCCAGGG CCAAATCTAT CCCAACCAAA ACCTACTCCA ATGAGGTGGT GACACTGTGG 960

TACCGGCCTC CCGACATCCT GCTGGGCTCC ACAGACTACT CCACTCAGAT CGACATGTGG 1020

GGTGTGGGCT GCATTTTTTA CGAGATGGCC ACAGGCAGGC CCCTCTTCCC GGGCTCCACG 1080

GTGGAGGAGC AGCTGCATTT CATCTTTCGG ATCCTGGGGA CACCCACTGA AGAGACTTGG 1140

CCAGGAATTT CTTCCAACGA GGAGTTCAAG AACTACGACT ACCCCAAATA CCGGGCAGAG 1200

GCCCTGCTGA GCCATGCACC TCGGCTGGAC ACGGATGGGG CAGACCTCTT GGCTAAACTG 1260

CTGCAGTTCG AGGGTCGGAA TCGGATCTCT GCAGATGATG CCATGAGACA CCCCTTCTTC 1320

CAGAGTCTGG GGTCACGAAT CCATAAACTC CCTGACACTA CTTCCATATT TGCACTAAAG 1380

GAGATCCAGT TACAGAAGGA GACGGGCCTG CGCTCAGCCT CCCTCACAGA CTCGGGTGGG 1440

CCAGCCTTCC GGGTGGTGGA CACGGAGTTC TAG 1473

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y kl+k+geGty++vyk+k+k t+++vAlK+irle+e eg p+ta+rE+sllk+lkh+ni

Q: 159   YVKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKHANI  217

         7899********************************9.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v+L+++++ ++k+l+Lvfe+l++dLk++l+++ +  +++ +vk +l+qll+glay+H++k

Q: 218   VTLHDIIH-TDKSLTLVFEYLDKDLKQYLEDCGN-IINMYNVKLFLFQLLRGLAYCHRQK  275

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         +lHRDlKpqNlLi+++g+lklaDfGlara s p+kty++evvTlwYr+P++Llg+++Yst

Q: 276   VLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYST  335

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkseidqlerifkllgtpsekvwpevsklpeyk.ksfp  239

         ++D+W+vgci+ e++t +plf+g++  +ql+ if++lgtp+e++wp++s+ +e+k +++p

Q: 336   QIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGISSNEEFKnYDYP  395

         *******************************************************99***

S: 240   kkkkkklkekvkklkekaldllekllaldpkkRisakealqhkyf  284

         k++++ l ++ ++l++++ dll kll+++ ++Risa++a++h++f

Q: 396   KYRAEALLSHAPRLDTDGADLLAKLLQFEGRNRISADDAMRHPFF  440

         *******************************************98

Domain Sequence
(FASTA)

YVKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV 60

TLHDIIHTDK SLTLVFEYLD KDLKQYLEDC GNIINMYNVK LFLFQLLRGL AYCHRQKVLH 120

RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID 180

MWGVGCIFYE MATGRPLFPG STVEEQLHFI FRILGTPTEE TWPGISSNEE FKNYDYPKYR 240

AEALLSHAPR LDTDGADLLA KLLQFEGRNR ISADDAMRHP FF 282

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013