EKS-MOD-00232

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00232

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/MAPKAPK	427.5	1.9E-128	57	317	261

Status

Unreviewed

Ensembl Protein

ENSMODP00000014998

UniProt Accession

F7CUT8;

Protein Name

Protein Synonyms/Alias

Gene Name

MAPKAPK3

Gene Synonyms/Alias

MAPKAPK3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000011968	ENSMODP00000014998	ENSMODT00000015273

Organism

Monodelphis domestica

Functional Description

Protein Length

395

Protein Sequence
(FASTA)

MDPNGEREEQ TPEGQASGPG PGGAMGAGIQ GNAKSGPRSL AHGKVEPKKY AVTDDYKLSK 60

QVLGLGVNGK VLECFHKVTG QKCALKLLYE SPKARQEVEH HWQASGGPHI VRIMDVYENM 120

HNNRRCFLIV MECMEGGELF SRIQERGDQA FTEREASEIM RDIGTAIQYL HAMNIAHRDV 180

KPENLLYTSK GKDSVLKLTD FGFAKETTQN ALQTPCYTPY YVAPEVLGPE KYDKSCDMWS 240

LGVIMYILLC GFPPFYSNTG QAISPGMKRR IRMGQYGFPN PEWSDVSEEA KQLIRLLLKT 300

EPTERMTITQ FMNHPWINQS MVVPQTPLHT ARVLQEDKDH WDEVKEEMTS ALATMRVDYD 360

QVKIKDLKTS NNRLLNKRRK KQAGGSMSSS GCNNQ 395

Nucleotide Sequence
(FASTA)

ATGGACCCCA ATGGTGAACG GGAAGAGCAG ACACCTGAAG GACAAGCCTC AGGCCCTGGT 60

CCTGGGGGAG CCATGGGAGC AGGAATCCAA GGGAATGCCA AGAGTGGGCC TAGGAGTCTG 120

GCCCATGGCA AGGTTGAGCC CAAGAAGTAT GCGGTGACCG ATGATTACAA GCTGTCTAAA 180

CAAGTGCTGG GCCTGGGTGT GAATGGAAAG GTCTTGGAGT GCTTCCACAA GGTGACAGGC 240

CAGAAGTGTG CACTGAAGCT CCTGTATGAG AGTCCCAAGG CTCGTCAGGA AGTGGAACAC 300

CATTGGCAAG CCTCAGGTGG GCCCCATATT GTGCGCATCA TGGACGTGTA TGAGAACATG 360

CACAACAACA GGCGGTGCTT CCTTATTGTC ATGGAATGCA TGGAAGGTGG TGAGCTTTTT 420

AGCAGGATCC AGGAGCGAGG CGACCAGGCT TTCACCGAAA GAGAGGCCTC GGAGATCATG 480

AGAGACATTG GCACAGCCAT CCAGTACCTG CATGCCATGA ACATTGCCCA CCGAGATGTC 540

AAGCCAGAAA ATCTGCTCTA TACATCCAAA GGAAAAGACT CAGTACTCAA GCTTACGGAC 600

TTTGGATTTG CCAAGGAAAC CACTCAAAAT GCCCTACAGA CACCCTGCTA CACACCTTAT 660

TATGTGGCCC CCGAGGTGCT GGGTCCTGAG AAGTATGACA AGTCGTGTGA CATGTGGTCA 720

CTTGGGGTTA TCATGTACAT TCTTCTTTGT GGCTTCCCTC CATTCTACTC CAACACCGGC 780

CAAGCCATTT CCCCTGGAAT GAAGAGAAGG ATCCGAATGG GACAGTATGG ATTTCCCAAT 840

CCCGAATGGT CTGATGTCTC AGAAGAAGCC AAGCAACTGA TCCGACTCTT GTTAAAGACA 900

GAACCTACTG AAAGAATGAC CATCACCCAG TTCATGAACC ATCCTTGGAT TAATCAGTCA 960

ATGGTGGTCC CACAAACTCC TCTTCACACT GCCCGAGTCC TACAGGAAGA TAAAGACCAC 1020

TGGGATGAAG TGAAGGAAGA AATGACCAGT GCCCTGGCCA CTATGCGGGT AGATTATGAC 1080

CAAGTGAAAA TCAAAGACTT GAAAACTTCT AACAACCGGC TCCTTAATAA ACGTCGAAAG 1140

AAGCAGGCTG GTGGCTCCAT GTCCTCTTCA GGCTGCAACA ACCAGTAA 1188

Domain Profile

S: 1     klteevlGeGisgkvlecvkkktgekyalkilkdrkkvrrevelhvqasghknivelidv  60

         kl+++vlG G++gkvlec++k tg+k+alk+l++++k+r+eve+h+qasg ++iv+++dv

Q: 57    KLSKQVLGLGVNGKVLECFHKVTGQKCALKLLYESPKARQEVEHHWQASGGPHIVRIMDV  116

         5789********************************************************

S: 61    fensfedekrlllvlekleGGellsriqer..kaftekeasevvkdiasalkflhsknia  118

         +en++++++++l+v+e++eGGel+sriqer  +afte+ease+++di++a+++lh +nia

Q: 117   YENMHNNRRCFLIVMECMEGGELFSRIQERgdQAFTEREASEIMRDIGTAIQYLHAMNIA  176

         *******************************9****************************

S: 119   hrDlkpenlLyeskeknapvklcDfglaketeeeeelktpcltaeyvaPevleaekeeal  178

         hrD+kpenlLy+sk k++++kl+Dfg+ake +++++l+tpc+t++yvaPevl++ek

Q: 177   HRDVKPENLLYTSKGKDSVLKLTDFGFAKE-TTQNALQTPCYTPYYVAPEVLGPEK----  231

         *****************************7.7899*********************....

S: 179   lydksCDlWslGvilyillcGypPfyskkgraiskklkeriqegkyefPeeeWsevseea  238

          ydksCD+WslGvi+yillcG+pPfys++g+ais+++k+ri++g+y fP++eWs+vseea

Q: 232   -YDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGMKRRIRMGQYGFPNPEWSDVSEEA  290

         .***********************************************************

S: 239   kdlirklLkrdpkerltieevlnhpwv  265

         k+lir lLk++p+er+ti++++nhpw+

Q: 291   KQLIRLLLKTEPTERMTITQFMNHPWI  317

         **************************8

Domain Sequence
(FASTA)

KLSKQVLGLG VNGKVLECFH KVTGQKCALK LLYESPKARQ EVEHHWQASG GPHIVRIMDV 60

YENMHNNRRC FLIVMECMEG GELFSRIQER GDQAFTEREA SEIMRDIGTA IQYLHAMNIA 120

HRDVKPENLL YTSKGKDSVL KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC 180

DMWSLGVIMY ILLCGFPPFY SNTGQAISPG MKRRIRMGQY GFPNPEWSDV SEEAKQLIRL 240

LLKTEPTERM TITQFMNHPW I 261

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013