EKS-MOD-00260

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00260

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/PLK	372.1	1.6E-111	13	266	254

Status

Unreviewed

Ensembl Protein

ENSMODP00000041050

UniProt Accession

K7E5J8;

Protein Name

Protein Synonyms/Alias

Gene Name

PLK4

Gene Synonyms/Alias

PLK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000012263	ENSMODP00000015357	ENSMODT00000015643
ENSMODG00000012263	ENSMODP00000041050	ENSMODT00000044160

Organism

Monodelphis domestica

Functional Description

Protein Length

965

Protein Sequence
(FASTA)

MDGSLDTSTI EDFRVGTLLG KGSFAGVYRA EAIHSGLEVA IKMIDKKAMY KAGMVRRVQE 60

EVKIHCQLKH PSILELYNYF EDNNYVYLVL EMCHNGEVNR YLKNKMKPFS ESQARQFMHQ 120

IITGMLYLHS HGILHRDLTL SNLLLTRNMN IKIADFGIAT QLKMPNEKHY TLCGTPNYIS 180

PEVATRRAHG LETDVWSLGC MFYTLLVGRP PFDTDSITNT FNKVVLVDYK IPTFLSQEAK 240

DLIRRLLQKN PEDRLSLSSV LDHPFMCQSS SGRIKDSSTV EDSIDSGHAT ISTAITGSSS 300

ASMSGCLLDK KRLLFGQPLP NKMTLFPKNK NLSNFSSGDG SSFYPQWGFH EQESSHSGRG 360

RLQQDPEERP HSRYLRRAHS SDRSDTSSGH SQAKPPAVER CHSADIFSKP NRRGWPENEE 420

RFSPPSSNAN IFHPFKENIS NTPGFFERPD KDQAHPLHPG KSAFPFSDQT SQAEIVQQAN 480

AHLREPAAHI SINSSRNDQG HPNLQKDPRR NAWTDRMAHG DALASESVRC VKQPNAMKHM 540

PAHHQETETA PLAPVFGSHP LSDPSKSRGM EPQRGHQKCS LWSSTSPLNA LRLKPIRQKT 600

KKAVVSILDT EEVCVELLKE FDSQEYVKEV LLVSPDGKSI TVYYPNDGKG FPLGNKPLLP 660

PTDMTRYNFD SLPEKYWRKY QYASRFVQLV RSKTPKITAF SKYAKCILME NSPQADFEAW 720

FYDGAKIHKT EGLINMIEKS GKSYTLKGET DIDSLKEELK IYVDHANEEH RFCLALESVF 780

SEEETKSRIV PRFPIIVGRK PGNPVSPQTV APPTCRDPDA LGKDTASLNR MVASNPGVAT 840

HQTPKATPSF GSYDGPGFTA AVPETGGSST SPEDYLPKSA QLLKPVFVEN VGCVTQLPSG 900

AVWVHFNDGS QLVVQAGMPS ISYTSPNGQT TRYGEKETLP EYIKEKLQCL SSVLLMFAHP 960

TPGPP 965

Nucleotide Sequence
(FASTA)

ATGGACGGGT CTCTGGATAC CTCCACCATC GAGGATTTCA GGGTCGGGAC CCTCCTGGGA 60

AAGGGGTCTT TCGCTGGTGT CTACAGAGCT GAGGCCATCC ACTCAGGCCT GGAAGTTGCA 120

ATCAAAATGA TTGATAAAAA GGCCATGTAC AAAGCTGGGA TGGTCCGGAG GGTCCAGGAA 180

GAAGTGAAGA TCCACTGTCA ACTGAAACAT CCTTCTATCC TGGAGCTTTA TAACTATTTT 240

GAAGATAACA ATTATGTGTA TCTGGTATTA GAAATGTGTC ATAATGGAGA AGTGAACAGG 300

TATTTGAAGA ACAAAATGAA ACCTTTCTCA GAAAGCCAAG CTCGACAGTT CATGCACCAG 360

ATCATCACAG GAATGCTGTA TCTTCATTCT CATGGTATAT TACATCGGGA CCTCACACTT 420

TCAAACCTCT TACTGACACG GAATATGAAT ATCAAGATTG CTGATTTTGG GATAGCAACT 480

CAGTTGAAAA TGCCTAATGA AAAACACTAT ACACTATGTG GCACTCCTAA TTATATTTCC 540

CCAGAAGTTG CCACTCGAAG AGCACATGGA CTTGAAACTG ATGTTTGGTC TCTAGGGTGT 600

ATGTTTTATA CATTACTTGT TGGGCGGCCC CCTTTTGACA CGGACTCAAT CACAAATACA 660

TTTAATAAAG TGGTATTGGT AGATTACAAA ATACCCACCT TTTTGTCACA AGAGGCCAAG 720

GACCTTATTC GTCGATTGCT TCAGAAAAAT CCAGAAGACC GTTTAAGTCT GTCCTCAGTG 780

TTGGATCATC CTTTTATGTG TCAAAGTTCT TCGGGGAGAA TTAAGGATTC CAGCACTGTA 840

GAAGATTCAA TAGATAGTGG ACATGCTACC ATTTCTACAG CAATTACCGG TTCTTCCAGT 900

GCCAGTATGA GTGGTTGTTT ACTGGACAAG AAGAGACTAT TATTTGGTCA GCCACTTCCA 960

AATAAAATGA CTCTATTTCC AAAGAATAAG AACCTGAGTA ATTTTTCATC TGGTGATGGA 1020

AGCAGTTTTT ATCCTCAGTG GGGATTTCAT GAACAAGAAA GCAGTCACAG TGGCCGGGGA 1080

AGACTACAAC AAGATCCTGA AGAAAGGCCA CATTCTCGAT ACCTGCGCAG AGCCCACTCC 1140

TCTGATCGAT CCGATACTTC GAGTGGTCAC TCCCAAGCCA AACCACCTGC TGTGGAGCGC 1200

TGTCACTCTG CAGATATCTT CTCAAAGCCC AACAGGAGAG GATGGCCAGA AAATGAAGAG 1260

AGGTTTTCAC CTCCCAGCAG CAATGCTAAT ATTTTTCACC CATTTAAAGA AAATATCTCT 1320

AATACTCCTG GCTTTTTTGA AAGACCTGAT AAAGACCAAG CACATCCTCT CCATCCTGGA 1380

AAATCTGCTT TTCCGTTTTC AGACCAGACC TCTCAAGCTG AAATAGTTCA ACAAGCAAAT 1440

GCTCATTTAA GAGAGCCTGC TGCTCACATC AGCATTAACT CAAGCAGAAA TGACCAGGGT 1500

CATCCAAATT TGCAGAAGGA CCCAAGGAGA AATGCCTGGA CTGACAGGAT GGCTCACGGG 1560

GATGCATTAG CTTCTGAGAG TGTGCGTTGT GTCAAACAGC CAAATGCCAT GAAACATATG 1620

CCTGCCCATC ACCAGGAAAC CGAAACTGCT CCGTTAGCAC CTGTGTTTGG CTCACATCCT 1680

CTTTCTGACC CAAGCAAATC TAGGGGCATG GAGCCACAAA GAGGCCACCA GAAATGTTCC 1740

TTGTGGAGCT CAACCTCTCC TTTGAATGCC CTCAGGCTCA AGCCCATCAG GCAAAAGACG 1800

AAAAAAGCAG TGGTGAGTAT ACTTGACACA GAAGAGGTGT GTGTGGAGCT GCTGAAGGAA 1860

TTTGATTCCC AGGAGTACGT GAAGGAAGTT CTTCTGGTGT CCCCTGATGG AAAATCGATC 1920

ACAGTTTATT ATCCAAATGA TGGAAAAGGT TTCCCTCTTG GAAATAAACC ACTCCTTCCT 1980

CCCACAGACA TGACTAGGTA TAACTTTGAT TCTTTACCAG AAAAATACTG GAGAAAGTAT 2040

CAATATGCTT CCAGATTTGT ACAGCTTGTA AGATCTAAAA CACCTAAAAT CACTGCCTTT 2100

TCAAAATATG CTAAGTGCAT TTTGATGGAG AATTCCCCTC AGGCTGACTT TGAAGCTTGG 2160

TTTTATGATG GAGCAAAAAT ACACAAAACT GAAGGCTTGA TTAACATGAT TGAAAAATCT 2220

GGAAAATCCT ACACTTTGAA AGGAGAGACT GATATTGATA GTTTGAAAGA AGAACTAAAA 2280

ATATATGTAG ATCATGCTAA TGAGGAACAT CGTTTTTGCC TTGCACTGGA ATCTGTTTTT 2340

TCAGAAGAAG AAACAAAAAG TAGAATTGTT CCCCGCTTTC CGATAATTGT TGGAAGAAAG 2400

CCAGGCAACC CTGTTTCCCC ACAGACTGTG GCCCCTCCAA CTTGCAGGGA TCCAGATGCT 2460

TTAGGAAAAG ACACGGCATC GTTGAATAGG ATGGTGGCGA GCAACCCCGG GGTTGCTACT 2520

CACCAGACAC CCAAGGCCAC TCCTTCTTTT GGTTCATATG ACGGACCTGG GTTCACAGCA 2580

GCTGTGCCTG AAACAGGAGG ATCTTCGACC AGCCCAGAGG ATTATCTTCC CAAATCAGCG 2640

CAGCTTCTAA AGCCTGTTTT TGTGGAAAAT GTTGGTTGTG TTACACAGCT ACCCAGTGGG 2700

GCTGTGTGGG TTCACTTCAA TGATGGATCC CAGTTGGTGG TTCAGGCTGG AATGCCCTCT 2760

ATCAGTTACA CCTCACCAAA TGGCCAGACT ACTCGGTACG GGGAAAAAGA AACGTTACCA 2820

GAATACATCA AAGAGAAATT ACAGTGTCTG TCTTCTGTCC TGCTGATGTT TGCTCACCCC 2880

ACTCCAGGCC CCCCCTGA 2898

Domain Profile

S: 1     yergkllGkGgfakcyelkdletkevfavkvvpksllakekqrekvekeieihrslkhkn  60

         +++g llGkG+fa +y+++ ++++ ++a+k+++k++++k+ +  +v++e++ih++lkh++

Q: 13    FRVGTLLGKGSFAGVYRAEAIHSGLEVAIKMIDKKAMYKAGMVRRVQEEVKIHCQLKHPS  72

         67899*******************************************************

S: 61    ivklyeffedkenvylvlelcsrrslaellkrr.kaltepevryylrqivsglkylhekr  119

         i++ly++fed+++vylvle+c++++++++lk++ k+++e+++r +++qi++g++ylh++

Q: 73    ILELYNYFEDNNYVYLVLEMCHNGEVNRYLKNKmKPFSESQARQFMHQIITGMLYLHSHG  132

         *******************************999**************************

S: 120   ilhrdlklgnlflneelevkigdfGlatrlekeeerkktlcGtPnyiaPevlskkghsle  179

         ilhrdl+l+nl+l++++++ki+dfG+at+l++++e+++tlcGtPnyi+Pev+++++h+le

Q: 133   ILHRDLTLSNLLLTRNMNIKIADFGIATQLKMPNEKHYTLCGTPNYISPEVATRRAHGLE  192

         ************************************************************

S: 180   vdiWslGcilytllvGkPPfetkelketyekikkaeyslPsslskeaksliakllkkePe  239

         +d+WslGc++ytllvG+PPf+t+++ +t++k++  +y++P+ ls+eak+li++ll+k+Pe

Q: 193   TDVWSLGCMFYTLLVGRPPFDTDSITNTFNKVVLVDYKIPTFLSQEAKDLIRRLLQKNPE  252

         ************************************************************

S: 240   erpsleevlkdefl  253

         +r+sl++vl+++f+

Q: 253   DRLSLSSVLDHPFM  266

         ************98

Domain Sequence
(FASTA)

FRVGTLLGKG SFAGVYRAEA IHSGLEVAIK MIDKKAMYKA GMVRRVQEEV KIHCQLKHPS 60

ILELYNYFED NNYVYLVLEM CHNGEVNRYL KNKMKPFSES QARQFMHQII TGMLYLHSHG 120

ILHRDLTLSN LLLTRNMNIK IADFGIATQL KMPNEKHYTL CGTPNYISPE VATRRAHGLE 180

TDVWSLGCMF YTLLVGRPPF DTDSITNTFN KVVLVDYKIP TFLSQEAKDL IRRLLQKNPE 240

DRLSLSSVLD HPFM 254

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>