EKS-MOD-00040

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00040

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CK1/VRK	430.9	1.7E-129	48	314	267

Status

Unreviewed

Ensembl Protein

ENSMODP00000031766

UniProt Accession

F6QLF8;

Protein Name

Protein Synonyms/Alias

Gene Name

VRK1

Gene Synonyms/Alias

VRK1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000012904	ENSMODP00000031766	ENSMODT00000033341

Organism

Monodelphis domestica

Functional Description

Protein Length

412

Protein Sequence
(FASTA)

MDSAIYFLTG KMPRIKTSQP RRRGAVQRKL AEQFAAGEVL IDLRKQEWKV GQPIGQGGFG 60

CLYLADTNSS NSVGVDARCV IKVEPSDNGP LFTELKFYQR AAKPEQIKKW IHSHKLKYLG 120

IPKYWGSGLH DKNGNSYRFM VMDRFGSDLQ KLHEANAKKF SRKTVLQLSL RILDILEYIH 180

EHEYVHGDIK ASNLLLSYEN PDQVYLVDYG LAYRYCPEGI HKEYREDPKR CHDGTIEFTS 240

IDAHKGVAPS RRGDLEILGY CMIHWLSGYL PWEDNLKDPN YVRDSKISYR ENIASLMDKC 300

FPEKNKPDEI AKYLEEVKLL EYTEKPHYQR LREILLQGLK ATGSNDDGKL DLHILQNGDL 360

PTKKRKKEVE ENIESGVEDM EISTRSILEG AQTRNDHDVL RITTSKHISS TD 412

Nucleotide Sequence
(FASTA)

ATGGACAGTG CTATTTACTT CCTGACAGGG AAAATGCCTC GTATTAAAAC ATCACAACCT 60

AGAAGAAGAG GTGCTGTGCA GAGAAAGCTG GCAGAACAGT TTGCAGCTGG GGAAGTTTTA 120

ATTGACCTGA GGAAACAAGA ATGGAAAGTA GGACAACCCA TTGGCCAAGG TGGTTTTGGC 180

TGCCTATATC TTGCTGATAC TAATTCTTCA AATTCGGTTG GTGTTGATGC CCGTTGTGTT 240

ATAAAAGTGG AACCAAGTGA CAATGGACCT CTTTTTACTG AACTAAAGTT CTATCAGAGA 300

GCTGCTAAAC CAGAGCAAAT TAAAAAATGG ATTCATTCCC ATAAACTGAA GTACCTGGGT 360

ATTCCTAAGT ATTGGGGTTC TGGACTACAT GATAAAAATG GAAACAGTTA CAGGTTTATG 420

GTAATGGATC GTTTTGGGAG CGATCTCCAA AAGTTGCATG AAGCTAATGC TAAAAAGTTT 480

TCACGAAAAA CTGTCTTGCA GCTAAGTTTA AGAATACTGG ATATTTTGGA ATATATCCAT 540

GAGCATGAAT ATGTACATGG AGATATCAAG GCCTCAAATC TTCTTCTGAG CTATGAGAAT 600

CCCGACCAGG TATATTTAGT AGATTATGGC CTTGCTTACC GATATTGTCC AGAAGGAATT 660

CATAAAGAGT ACAGAGAAGA TCCTAAAAGG TGTCATGATG GAACCATTGA ATTTACAAGT 720

ATTGATGCAC ATAAGGGTGT GGCACCATCA AGACGGGGTG ATTTGGAAAT ACTAGGTTAC 780

TGCATGATCC ATTGGCTCAG TGGCTATCTC CCTTGGGAAG ACAATTTGAA GGATCCTAAT 840

TACGTCAGAG ATTCCAAAAT CAGCTACCGA GAAAATATTG CAAGTTTGAT GGACAAGTGT 900

TTTCCTGAGA AAAATAAGCC AGATGAAATT GCTAAATATC TTGAAGAAGT AAAATTACTG 960

GAATATACAG AAAAACCTCA TTATCAGCGT TTACGAGAAA TTCTTTTGCA AGGTCTAAAG 1020

GCTACAGGAA GTAACGACGA CGGCAAACTG GACTTACATA TCTTGCAAAA TGGAGATTTG 1080

CCAACAAAAA AGCGAAAGAA AGAAGTAGAA GAAAACATAG AATCAGGGGT TGAAGATATG 1140

GAAATCTCAA CTAGAAGTAT ATTGGAGGGA GCTCAAACTC GAAATGATCA TGATGTTCTG 1200

AGGATCACTA CATCAAAGCA TATCTCAAGC ACTGATTAA 1239

Domain Profile

S: 1     wklgkkigkggfGeiyla..ltckkeekdaklvvkvepkenGpLfvelkfyqraakkeqi  58

         wk+g++ig+ggfG++yla  +++++++ da++v+kvep++nGpLf+elkfyqraak+eqi

Q: 48    WKVGQPIGQGGFGCLYLAdtNSSNSVGVDARCVIKVEPSDNGPLFTELKFYQRAAKPEQI  107

         9*****************999999************************************

S: 59    kkwkkkkklkllgiPtliasGlhefegekyRflvlprlgrdLqklleqngkrlsektvlq  118

         kkw++ +klk+lgiP++++sGlh+++g++yRf+v++r+g+dLqkl e+n+k++s+ktvlq

Q: 108   KKWIHSHKLKYLGIPKYWGSGLHDKNGNSYRFMVMDRFGSDLQKLHEANAKKFSRKTVLQ  167

         ************************************************************

S: 119   lavrlldvleylHeneYvHgdikAanllleeeeasqvyLvdyGlayrycpegkhkeyked  178

         l++r+ld+ley+He+eYvHgdikA+nlll++e+++qvyLvdyGlayrycpeg hkey+ed

Q: 168   LSLRILDILEYIHEHEYVHGDIKASNLLLSYENPDQVYLVDYGLAYRYCPEGIHKEYRED  227

         ************************************************************

S: 179   krraHdGtleftslDaHkGvapsrRsDleiLgYcllkWltgkLPWeallkdpekvqkake  238

         ++r+HdGt+efts+DaHkGvapsrR+DleiLgYc+++Wl+g+LPWe++lkdp++v+++k

Q: 228   PKRCHDGTIEFTSIDAHKGVAPSRRGDLEILGYCMIHWLSGYLPWEDNLKDPNYVRDSKI  287

         ************************************************************

S: 239   kfldelpellkkllkkkssseelakyl  265

          + +++++l++k++++k+++ e+akyl

Q: 288   SYRENIASLMDKCFPEKNKPDEIAKYL  314

         **************************8

Domain Sequence
(FASTA)

WKVGQPIGQG GFGCLYLADT NSSNSVGVDA RCVIKVEPSD NGPLFTELKF YQRAAKPEQI 60

KKWIHSHKLK YLGIPKYWGS GLHDKNGNSY RFMVMDRFGS DLQKLHEANA KKFSRKTVLQ 120

LSLRILDILE YIHEHEYVHG DIKASNLLLS YENPDQVYLV DYGLAYRYCP EGIHKEYRED 180

PKRCHDGTIE FTSIDAHKGV APSRRGDLEI LGYCMIHWLS GYLPWEDNLK DPNYVRDSKI 240

SYRENIASLM DKCFPEKNKP DEIAKYL 267

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>