EKS-MOD-00150

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00150

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
AGC/NDR	518.3	5.9E-156	89	382	294

Status

Unreviewed

Ensembl Protein

ENSMODP00000016955

UniProt Accession

F7C3H3;

Protein Name

Protein Synonyms/Alias

Gene Name

STK38

Gene Synonyms/Alias

STK38;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000013550	ENSMODP00000016955	ENSMODT00000017269

Organism

Monodelphis domestica

Functional Description

Protein Length

465

Protein Sequence
(FASTA)

MAMTGSTPCS SMSNHTKERV TMTKVTLENF YSNLIAQHEE REMRQKKLEK VMEEEGLKDE 60

EKRLRRSAHA RKETEFLRLK RTRLGLEDFE SLKVIGRGAF GEVRLVQKKD TGHVYAMKIL 120

RKADMLEKEQ VGHIRAERDI LVEADSLWVV KMFYSFQDKL NLYLIMEFLP GGDMMTLLMK 180

KDTLTEEETQ FYIAETVLAI DSIHQLGFIH RDIKPDNLLL DSKGHVKLSD FGLCTGLKKA 240

HRTEFYRNLN HSLPSDFTFQ NMNSKRKAET WKRNRRQLAF STVGTPDYIA PEVFMQTGYN 300

KLCDWWSLGV IMYEMLIGYP PFCSETPQET YKKVMNWKET LTFPPEVPIS EKAKDLILRF 360

CCEWEHRIGA PGVEEIKSNP FFEGVDWEHI RERPAAISIE IRSIDDTSNF DEFPESDILK 420

PTVATSNHPE TDYKNKDWVF INYTYKRFEG LTARGAIPSY MKTGK 465

Nucleotide Sequence
(FASTA)

ATGGCAATGA CAGGCTCAAC ACCTTGTTCA TCCATGAGCA ACCATACGAA GGAACGAGTC 60

ACTATGACAA AAGTGACATT GGAGAATTTT TACAGCAACC TTATTGCACA ACATGAAGAA 120

CGGGAAATGA GACAAAAGAA GCTAGAGAAA GTGATGGAAG AAGAAGGCTT AAAAGATGAA 180

GAGAAGCGAC TCAGGAGATC AGCACATGCT CGGAAGGAAA CAGAGTTTCT TCGACTAAAA 240

AGAACAAGGC TTGGACTGGA AGACTTTGAG TCCTTAAAAG TAATAGGCAG AGGAGCATTT 300

GGTGAGGTGA GGCTTGTTCA GAAGAAAGAT ACAGGCCACG TATATGCAAT GAAAATACTT 360

CGTAAAGCAG ATATGCTTGA AAAAGAGCAG GTTGGCCACA TTCGTGCGGA GCGTGACATT 420

CTAGTGGAGG CAGACAGTTT GTGGGTTGTG AAAATGTTCT ATAGTTTTCA GGATAAGCTA 480

AACCTCTACC TAATCATGGA GTTCCTGCCT GGAGGTGACA TGATGACCTT ATTGATGAAA 540

AAAGATACTT TAACTGAAGA GGAGACTCAG TTCTACATAG CAGAAACAGT GTTAGCAATA 600

GACTCAATTC ATCAACTTGG ATTTATCCAT AGAGACATCA AACCAGACAA CCTCCTCTTG 660

GATAGTAAGG GCCATGTGAA GCTTTCTGAC TTTGGCCTCT GCACAGGACT AAAGAAAGCT 720

CATAGGACAG AATTTTATAG GAACTTGAAT CACAGTCTCC CCAGTGACTT CACTTTCCAG 780

AACATGAATT CCAAAAGGAA AGCAGAAACT TGGAAAAGAA ATAGACGCCA GCTAGCCTTC 840

TCCACAGTGG GCACTCCAGA TTACATTGCT CCTGAAGTCT TTATGCAAAC TGGATACAAT 900

AAGCTCTGTG ATTGGTGGTC TCTTGGGGTT ATCATGTATG AAATGCTCAT TGGTTACCCT 960

CCTTTCTGTT CTGAAACTCC TCAAGAAACC TACAAGAAAG TGATGAATTG GAAAGAAACA 1020

CTGACTTTTC CTCCAGAAGT TCCAATCTCT GAGAAAGCTA AGGATCTTAT TTTAAGATTC 1080

TGTTGTGAAT GGGAACATAG AATTGGAGCC CCTGGAGTTG AAGAAATTAA GAGTAATCCT 1140

TTTTTTGAAG GAGTTGACTG GGAACATATC AGGGAGAGAC CAGCTGCAAT ATCAATTGAG 1200

ATAAGAAGCA TTGATGACAC CTCAAACTTT GATGAATTTC CCGAATCTGA TATTCTTAAG 1260

CCCACAGTGG CTACAAGTAA CCACCCAGAG ACGGACTACA AGAACAAAGA TTGGGTCTTC 1320

ATCAACTATA CTTACAAACG CTTTGAGGGC CTGACGGCAC GAGGAGCAAT ACCTTCCTAT 1380

ATGAAAACAG GAAAATAG 1398

Domain Profile

S: 1     feklkvigkGafGevrlvrkkdtkevyalkilrkkdllkknqvahvkaerdilaeadsew  60

         fe+lkvig+GafGevrlv+kkdt++vya+kilrk+d+l+k+qv h++aerdil+eads w

Q: 89    FESLKVIGRGAFGEVRLVQKKDTGHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLW  148

         899*********************************************************

S: 61    vvklyysfqdkenlylvmeylPGGdlmtllikkeilkeelarfyiaelvlavesvhklGf  120

         vvk++ysfqdk nlyl+me+lPGGd+mtll+kk++l+ee+++fyiae+vla++s+h+lGf

Q: 149   VVKMFYSFQDKLNLYLIMEFLPGGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGF  208

         ************************************************************

S: 121   ihrdlkPdnllidakGhikltdfGlctGlkkthrseyykelekakeddleaseelkvler  180

         ihrd+kPdnll+d+kGh+kl+dfGlctGlkk+hr+e+y++l+++ ++d+ ++    ++++

Q: 209   IHRDIKPDNLLLDSKGHVKLSDFGLCTGLKKAHRTEFYRNLNHSLPSDFTFQ----NMNS  264

         *************************************************555....5555

S: 181   rkk....kknrrllayslvGtpdyiapevlekkgynklcdwWslGvilyemlvGypPfla  236

         ++k    k+nrr+la+s+vGtpdyiapev++++gynklcdwWslGvi+yeml+GypPf++

Q: 265   KRKaetwKRNRRQLAFSTVGTPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCS  324

         5544556*****************************************************

S: 237   etpqetykkvinwketlkfpeevelseeakdlierliadaekrlgkkGvdeikkhpff  294

         etpqetykkv+nwketl+fp+ev++se+akdli r+++++e+r+g+ Gv+eik++pff

Q: 325   ETPQETYKKVMNWKETLTFPPEVPISEKAKDLILRFCCEWEHRIGAPGVEEIKSNPFF  382

         *********************************************************9

Domain Sequence
(FASTA)

FESLKVIGRG AFGEVRLVQK KDTGHVYAMK ILRKADMLEK EQVGHIRAER DILVEADSLW 60

VVKMFYSFQD KLNLYLIMEF LPGGDMMTLL MKKDTLTEEE TQFYIAETVL AIDSIHQLGF 120

IHRDIKPDNL LLDSKGHVKL SDFGLCTGLK KAHRTEFYRN LNHSLPSDFT FQNMNSKRKA 180

ETWKRNRRQL AFSTVGTPDY IAPEVFMQTG YNKLCDWWSL GVIMYEMLIG YPPFCSETPQ 240

ETYKKVMNWK ETLTFPPEVP ISEKAKDLIL RFCCEWEHRI GAPGVEEIKS NPFF 294

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

mdo:100029034

;

InterPros

IPR000961	; AGC-kinase_C.
IPR011009	; Kinase-like_dom.
IPR017892	; Pkinase_C.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069	; Pkinase; 1.
PF00433	; Pkinase_C; 1.

SMARTs

SM00133	; S_TK_X; 1.
SM00220	; S_TKc; 1.

Prosites

PS51285	; AGC_KINASE_CTER; 1.
PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013