EPS-MOD-00069

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MOD-00069

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Asp-Based PTP/FCP	114.4	5.7E-33	164	311	148

Status

Unreviewed

Ensembl Protein

ENSMODP00000016993

UniProt Accession

F7AVY5;

Protein Name

Protein Synonyms/Alias

Gene Name

TIMM50

Gene Synonyms/Alias

TIMM50;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000013584	ENSMODP00000016993	ENSMODT00000017307

Organism

Monodelphis domestica

Functional Description

Protein Length

369

Protein Sequence
(FASTA)

MAASVAAAAL PSRLRGGHWL RLRPQLRLLP LARALCARMV TPPRGPGQSQ MQDLPLPTHR 60

KQQQQHQQQQ QQQQGPSYAK KLAMWVAGLL GAGGTVSVIY VFGNNSVDEN GMKIPDEFDN 120

DPVLIQQLRR TYKYFKDYRQ MIIEPTSPCL LPDPLQEPYY QPPYTLVLEL TGVLLHPEWS 180

LATGWRFKKR PGIETLFQQL APLYEIVIFT SETGMTAFPL IDSVDPHGFI SYRLFRDATR 240

YMDGHHIKDI SCLNRDPARV VVVDCKKEAF RLQPNNGVAL RPWDGNSDDR TLLDLSAFLK 300

TIALNRVEDV RTVLENYALE EDPLEAFRQR QSRLEQEEQQ RMADLAKTTK QSLFFSSLTS 360

RLWPRSKQP 369

Nucleotide Sequence
(FASTA)

ATGGCGGCCT CGGTGGCGGC GGCGGCGCTT CCTTCACGTT TGCGGGGCGG TCACTGGCTG 60

CGGTTGCGGC CCCAGCTCAG ACTCTTACCC TTGGCCAGGG CCTTGTGCGC GCGAATGGTG 120

ACCCCACCGC GCGGCCCAGG ACAGAGCCAG ATGCAGGACC TGCCCTTGCC CACACATCGA 180

AAGCAGCAGC AGCAGCACCA ACAGCAGCAG CAGCAGCAGC AGGGCCCCAG CTATGCCAAG 240

AAGCTGGCCA TGTGGGTGGC GGGGCTCCTC GGGGCTGGGG GGACCGTCAG CGTCATCTAT 300

GTCTTTGGAA ACAACTCTGT GGATGAGAAC GGCATGAAGA TTCCAGATGA GTTTGACAAT 360

GATCCTGTGT TGATTCAGCA GCTTCGTCGA ACATACAAGT ATTTTAAGGA TTATCGACAG 420

ATGATCATTG AGCCCACCAG TCCCTGCCTC CTCCCAGACC CTCTTCAGGA GCCATATTAC 480

CAACCCCCGT ATACACTTGT CCTGGAACTG ACGGGTGTCC TGCTGCACCC CGAGTGGTCG 540

CTGGCCACAG GTTGGCGGTT CAAGAAGCGT CCCGGCATCG AGACCCTCTT TCAGCAGCTG 600

GCCCCTCTCT ATGAGATCGT CATCTTCACC TCTGAGACCG GCATGACAGC ATTTCCCCTC 660

ATCGACAGTG TGGACCCTCA TGGCTTCATC TCCTACCGCC TCTTTCGGGA TGCTACCCGC 720

TACATGGATG GGCACCATAT CAAGGACATC TCGTGCCTCA ACAGAGACCC TGCACGAGTG 780

GTAGTGGTGG ACTGTAAGAA GGAGGCTTTC CGGCTTCAGC CTAACAATGG TGTGGCCCTG 840

CGACCCTGGG ATGGGAACTC TGATGACCGA ACTCTGCTCG ACTTGTCTGC CTTCCTCAAG 900

ACCATTGCCC TGAATAGGGT GGAGGATGTC CGGACCGTCT TAGAGAACTA CGCGCTAGAA 960

GAAGACCCGC TGGAGGCCTT CCGACAGCGG CAGTCTCGCC TGGAACAGGA GGAGCAACAG 1020

CGCATGGCTG ACCTCGCCAA GACCACCAAA CAGAGCCTTT TCTTTAGTTC TCTCACCAGC 1080

CGCCTCTGGC CCCGATCCAA ACAGCCCTGA 1110

Domain Profile

S: 1     ktLVLDLDetLvhsksekdeeeektkasvkkRPgldeFLkelskayevviftasskeyad  60

         +tLVL+L ++L+h +++       t +++kkRPg + ++++l+  ye+vift+++ ++a

Q: 164   YTLVLELTGVLLHPEWSLA-----TGWRFKKRPGIETLFQQLAPLYEIVIFTSETGMTAF  218

         69*************9776.....9***********************************

S: 61    avldkldpkkklfkkrlyresctlengkyvKdLsllgrdlskvvivDdsprsfelqpdnl  120

         +++d +dp + ++++rl+r+ +++ +g+++Kd+s l+rd  +vv+vD ++++f+lqp+n+

Q: 219   PLIDSVDP-HGFISYRLFRDATRYMDGHHIKDISCLNRDPARVVVVDCKKEAFRLQPNNG  277

         ********.6799**************99*******************************

S: 121   ipiepfygdsdkdtellkllpfleale..ksddvr  153

         + ++p+ g+ ++d++ll+l+ fl+ ++  +++dvr

Q: 278   VALRPWDGN-SDDRTLLDLSAFLKTIAlnRVEDVR  311

         ********9.999**********999985559997

Domain Sequence
(FASTA)

YTLVLELTGV LLHPEWSLAT GWRFKKRPGI ETLFQQLAPL YEIVIFTSET GMTAFPLIDS 60

VDPHGFISYR LFRDATRYMD GHHIKDISCL NRDPARVVVV DCKKEAFRLQ PNNGVALRPW 120

DGNSDDRTLL DLSAFLKTIA LNRVEDVR 148

Keyword

Complete proteome; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005744	; C:mitochondrial inner membrane presequence translocase complex
GO:0016607	; C:nuclear speck
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0004725	; F:protein tyrosine phosphatase activity
GO:0043021	; F:ribonucleoprotein complex binding
GO:0007006	; P:mitochondrial membrane organization
GO:0001836	; P:release of cytochrome c from mitochondria

KEGG

InterPros

IPR023214	; HAD-like_dom.
IPR004274	; NIF.

Pfam

PF03031

; NIF; 1.

SMARTs

SM00577

; CPDc; 1.

Prosites

PS50969

; FCP1; 1.

Prints

Created Date

20-Feb-2013