EKS-MOD-00206

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00206

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	484.5	8.0E-146	4	286	283

Status

Unreviewed

Ensembl Protein

ENSMODP00000017752

UniProt Accession

F6TR05;

Protein Name

Protein Synonyms/Alias

Gene Name

CDKL3

Gene Synonyms/Alias

CDKL3;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000014201	ENSMODP00000017752	ENSMODT00000018080

Organism

Monodelphis domestica

Functional Description

Protein Length

590

Protein Sequence
(FASTA)

MEMYETLGKV GEGSYGTVMK CKHKDTGQIV AIKIFYEKPE KSVNKIAMRE IKFLKQFRHE 60

NLVNLIEVFR QKKKIHLVFE FIDHTVLDEL QHYCHGLESK RLRKYLFQIL RAIEYLHNNN 120

IIHRDIKPEN ILVSQSGITK LCDFGFARTL AAPGDIYTDY VATRWYRAPE LVLKDTTYGK 180

PVDIWALGCM IIEMATGNPY LPSSSDLDLL HKIVIKVGNL TPHLQNVFSR SPIFAGVVLP 240

QVQHPKNARK KYPKLNGLLA DIVHACLQID PAERVSSTDL LNHDYFTRDG FIEKFIPELK 300

AKLLQEAKVN SFIKPREYSK EIEPTKEDKK TTYINTLPNN SIIGKDVDKD KKTKDIKVRA 360

YKIKGGKGDI SDSKKIDHEG GYCQRDTSEN FHTFSQDKPV TTESPIPANF NIDSNMKEDS 420

HTSGCITIPP INPNSSNFTA ANPNSHFTHT NTSNKTSEKA KKRRTSSQSL IQSVSNNKQE 480

DSGFVQNQTE RGTLHDRISQ NDQTANGNKR KLNLTRNDKK EIHFPELPFT IQSKEMKVME 540

VKQIKVLKRE QKKTDTSKIP TLLNVDQNQE KPENTGIAQT KRKKNLPDIE 590

Nucleotide Sequence
(FASTA)

ATGGAGATGT ATGAAACTCT TGGAAAAGTG GGAGAGGGAA GTTATGGAAC AGTCATGAAG 60

TGTAAACATA AGGATACTGG GCAGATAGTG GCCATTAAGA TATTTTATGA AAAACCGGAA 120

AAATCTGTCA ACAAAATTGC AATGAGAGAA ATAAAGTTTC TTAAGCAATT TCGTCATGAA 180

AACCTGGTCA ATCTGATTGA AGTATTTAGA CAGAAAAAGA AAATTCATTT GGTATTTGAA 240

TTTATTGATC ACACAGTTTT AGATGAGTTA CAGCATTATT GTCATGGACT TGAGAGTAAA 300

CGACTGAGAA AATACCTCTT CCAGATCCTT CGAGCAATTG AATATCTTCA CAACAACAAT 360

ATCATTCATC GAGATATAAA ACCTGAGAAT ATTTTAGTTT CCCAATCTGG AATTACTAAG 420

CTTTGTGATT TTGGTTTTGC TCGGACATTA GCAGCCCCTG GAGACATTTA TACAGATTAT 480

GTGGCTACTC GCTGGTATAG AGCTCCTGAA TTAGTGCTAA AAGATACCAC TTATGGAAAA 540

CCTGTGGACA TTTGGGCTTT AGGCTGCATG ATCATTGAAA TGGCCACTGG GAATCCCTAT 600

CTTCCTAGCA GCTCTGATTT GGATTTGCTT CATAAAATTG TGATAAAAGT AGGCAATTTG 660

ACACCTCACT TGCAGAATGT TTTTTCCAGG AGTCCCATTT TTGCTGGGGT AGTTCTTCCT 720

CAAGTTCAGC ATCCTAAAAA TGCAAGAAAA AAGTATCCAA AGCTAAATGG ATTACTGGCA 780

GACATAGTCC ATGCTTGTTT ACAAATTGAT CCTGCGGAGA GGGTGTCATC TACAGATCTT 840

CTGAATCATG ACTACTTTAC TAGAGATGGG TTCATTGAAA AATTCATACC AGAACTGAAG 900

GCTAAATTAC TACAAGAAGC AAAAGTCAAT TCATTCATAA AGCCCAGAGA ATATTCTAAA 960

GAAATTGAAC CCACTAAAGA AGACAAGAAA ACAACCTACA TAAATACATT GCCAAATAAT 1020

TCAATTATAG GAAAGGATGT GGACAAGGAC AAAAAGACCA AAGATATTAA AGTCAGAGCT 1080

TATAAAATAA AAGGAGGGAA AGGAGATATT TCTGACAGTA AAAAGATAGA CCATGAAGGA 1140

GGATATTGCC AACGTGACAC TTCGGAAAAT TTTCACACTT TTTCTCAAGA TAAACCTGTA 1200

ACAACCGAAT CACCTATCCC TGCAAACTTC AACATTGATT CTAATATGAA GGAAGATTCC 1260

CACACTAGTG GTTGTATCAC CATACCACCC ATTAATCCAA ATAGCAGTAA TTTTACTGCT 1320

GCAAATCCTA ACTCACATTT CACCCACACA AATACAAGTA ATAAGACATC TGAAAAAGCT 1380

AAGAAGAGAA GGACTTCCTC ACAGTCCCTC ATACAATCTG TGTCTAACAA CAAGCAAGAG 1440

GATTCAGGCT TTGTTCAAAA TCAAACAGAG AGGGGCACAC TTCATGATCG AATATCTCAA 1500

AATGATCAAA CAGCAAATGG GAACAAAAGG AAATTGAATC TTACCAGGAA TGACAAGAAA 1560

GAGATCCATT TCCCAGAGCT GCCTTTCACA ATACAATCAA AGGAAATGAA AGTAATGGAA 1620

GTTAAACAGA TAAAGGTGCT GAAGAGAGAA CAAAAGAAAA CTGATACATC TAAAATACCA 1680

ACTTTACTTA ATGTGGATCA AAATCAGGAA AAACCAGAGA ATACAGGAAT TGCACAAACT 1740

AAAAGGAAGA AGAACCTGCC AGATATAGAG TAG 1773

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         ye+lgkvGeGsyG+v+kc++kdtgqivaik f+e+++ k+v+kia+reik+lkq++henl

Q: 4     YETLGKVGEGSYGTVMKCKHKDTGQIVAIKIFYEKPE-KSVNKIAMREIKFLKQFRHENL  62

         9***********************************9.9*********************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         vnl+evfr+kkk++lvfe++d+tvldel++y++G+e+++++k+l+qil+aie++h+nnii

Q: 63    VNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIEYLHNNNII  122

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarllaapgdvytdyvatrwyrapellvgdtkyGksv  180

         hrdikpenil+s+sg++klcdfGfar+laapgd+ytdyvatrwyrapel+++dt+yGk+v

Q: 123   HRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTTYGKPV  182

         ************************************************************

S: 181   dvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpev  240

         d+wa+Gc+++e++tG+p++p++sd+d l+ki+ ++G+l+p+ q++fs++++faGv+lp+v

Q: 183   DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVIKVGNLTPHLQNVFSRSPIFAGVVLPQV  242

         ************************************************************

S: 241   edleslekkypklnevlldllkkclkldpaerlsceellkheyf  284

         +++++++kkypkln +l+d++++cl++dpaer+s+++ll+h+yf

Q: 243   QHPKNARKKYPKLNGLLADIVHACLQIDPAERVSSTDLLNHDYF  286

         *******************************************9

Domain Sequence
(FASTA)

YETLGKVGEG SYGTVMKCKH KDTGQIVAIK IFYEKPEKSV NKIAMREIKF LKQFRHENLV 60

NLIEVFRQKK KIHLVFEFID HTVLDELQHY CHGLESKRLR KYLFQILRAI EYLHNNNIIH 120

RDIKPENILV SQSGITKLCD FGFARTLAAP GDIYTDYVAT RWYRAPELVL KDTTYGKPVD 180

IWALGCMIIE MATGNPYLPS SSDLDLLHKI VIKVGNLTPH LQNVFSRSPI FAGVVLPQVQ 240

HPKNARKKYP KLNGLLADIV HACLQIDPAE RVSSTDLLNH DYF 283

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Vicugna pacos"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013