EPS-MOD-00028

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MOD-00028

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	165.3	2.5E-48	330	508	179

Status

Unreviewed

Ensembl Protein

ENSMODP00000019531

UniProt Accession

F7F0V5;

Protein Name

Protein Synonyms/Alias

Gene Name

PPM1G

Gene Synonyms/Alias

PPM1G;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000015646	ENSMODP00000019531	ENSMODT00000019880

Organism

Monodelphis domestica

Functional Description

Protein Length

552

Protein Sequence
(FASTA)

MGAYLSQPNT VKSSGDGEGT AGSGGRGAQR LPLPYGFSAM QGWRVSMEDA HNCIPELDSE 60

TAMFSVYDGH GGEEVALYCA KYLPDIIKDQ KAYKEGKLQK ALEDAFLAID AKLTTEEVIK 120

ELAQIAGRPP EDEDEKEKVA DEDDVDNEEA ALLHEEATMT IEELLTRYGQ NCHKGPPHIK 180

AGAGLGEEPG SQGLNGEAGP EEPSGESSVE ENGPIAETHT DLSSTLERGT EAVQGDEPIT 240

PTGEAGPSCS STPAKPPRAA KSKFFEDSED ESDEAEEEEE DSEECSEDED GYSIGVEESF 300

TLIEQSFSDH RAMTVVLMVC FPFFSHIKPG SDSGTTAVVA LIRGKQLIVA NAGDSRCVVS 360

EAGKALDMSY DHKPEDELEL ARIKNAGGKV TMDGRVNGGL NLSRAIGDHF YKRNKNLPPE 420

EQMISALPDI KVLTLNEDHD FMVIACDGIW NVMSSQEVVD FIQAKISQRD ENGELRLLSS 480

IVEELLDQCL APDTSGDGTG CDNMTCIIIC FKPRSTATPQ PESGKRRLEE VVTPGAAGEN 540

GSSDNSKKAK QE 552

Nucleotide Sequence
(FASTA)

ATGGGCGCGT ACCTCTCCCA GCCCAACACG GTGAAGAGCT CTGGGGATGG GGAGGGCACC 60

GCGGGCTCGG GGGGACGCGG CGCCCAGCGT CTGCCGCTGC CCTACGGCTT CTCGGCTATG 120

CAAGGCTGGC GCGTCTCGAT GGAGGATGCT CACAACTGTA TTCCTGAATT GGACAGTGAG 180

ACAGCCATGT TTTCAGTCTA CGATGGACAT GGAGGGGAAG AAGTTGCACT GTACTGTGCT 240

AAATATCTCC CTGATATCAT CAAAGATCAG AAAGCATACA AAGAAGGAAA ACTACAGAAG 300

GCTTTGGAAG ATGCCTTCTT AGCTATTGAT GCCAAACTGA CCACAGAAGA GGTCATTAAA 360

GAGCTGGCCC AGATTGCAGG AAGGCCTCCT GAGGATGAGG ATGAAAAGGA AAAGGTGGCT 420

GATGAGGATG ATGTGGACAA TGAGGAAGCA GCCCTGCTTC ATGAAGAGGC CACCATGACC 480

ATTGAGGAAC TTCTAACACG CTACGGGCAG AACTGTCACA AGGGCCCTCC CCACATCAAG 540

GCTGGGGCTG GGTTGGGTGA GGAACCAGGG TCCCAGGGCC TCAATGGGGA GGCAGGGCCT 600

GAGGAGCCAT CAGGGGAATC CTCTGTGGAG GAGAATGGCC CCATAGCTGA GACCCACACA 660

GACCTTTCCT CCACCTTGGA ACGTGGGACT GAGGCAGTCC AGGGCGATGA GCCTATCACC 720

CCCACTGGAG AGGCTGGCCC CTCCTGCTCT TCCACCCCCG CCAAGCCACC TCGAGCTGCT 780

AAGTCCAAGT TCTTTGAGGA CAGTGAGGAT GAGTCAGATG AGGCAGAGGA GGAAGAGGAA 840

GACAGTGAGG AGTGCAGTGA AGATGAAGAT GGCTACAGCA TTGGGGTTGA AGAATCTTTT 900

ACCTTAATAG AGCAAAGTTT CAGTGATCAC CGGGCCATGA CAGTGGTCCT CATGGTATGT 960

TTTCCATTTT TTTCTCACAT AAAGCCTGGC TCAGACAGTG GCACAACAGC AGTGGTGGCT 1020

CTGATTCGGG GGAAGCAGCT GATTGTGGCA AATGCAGGAG ACTCTCGATG TGTGGTATCT 1080

GAAGCTGGCA AAGCCCTTGA TATGTCCTAT GACCATAAAC CTGAAGATGA ACTGGAGCTA 1140

GCACGAATCA AAAACGCTGG TGGCAAGGTT ACCATGGATG GTCGAGTCAA TGGAGGCCTC 1200

AACCTTTCTA GAGCCATTGG TGACCACTTC TATAAAAGAA ATAAGAATCT GCCACCCGAG 1260

GAGCAAATGA TCTCTGCACT GCCTGACATT AAGGTGCTAA CCCTCAATGA AGACCATGAC 1320

TTCATGGTCA TCGCTTGTGA TGGCATCTGG AATGTGATGA GCAGCCAGGA AGTGGTGGAT 1380

TTTATCCAGG CCAAGATCAG CCAGAGAGAT GAAAATGGGG AGCTTCGACT GCTCTCCTCC 1440

ATCGTGGAAG AGCTGTTGGA TCAGTGCCTG GCACCTGACA CTTCTGGGGA TGGCACTGGG 1500

TGTGACAACA TGACCTGCAT AATCATCTGC TTCAAACCCC GAAGCACAGC AACACCCCAG 1560

CCTGAGAGTG GCAAGAGGAG ACTAGAGGAG GTTGTGACCC CTGGAGCCGC TGGGGAGAAC 1620

GGCAGCAGTG ACAACAGCAA GAAAGCCAAA CAGGAATAG 1659

Domain Profile

S: 100   idksGstavvalikdsklyvanvGdSravLcrngkavelssdHkpsredEleRieeaggs  159

          + sG+tavvali++++l+van+GdSr+v +  gka+ +s dHkp+ e El+Ri++agg+

Q: 330   GSDSGTTAVVALIRGKQLIVANAGDSRCVVSEAGKALDMSYDHKPEDELELARIKNAGGK  389

         455*********************************************************

S: 160   vilkdgaRvlGvLavsRalGdlylk.........pyvtpePevtshrltsedefliLasD  210

         v+ +   Rv+G L++sRa+Gd ++k         +++++ P++ + +l+++++f+++a+D

Q: 390   VTMDG--RVNGGLNLSRAIGDHFYKrnknlppeeQMISALPDIKVLTLNEDHDFMVIACD  447

         ****9..*****************************************************

S: 211   Glwdvvsneeavslvrdvle......kkeaeqeaakkLvklalargsk......dnvsai  258

         G+w+v+s++e+v++++  ++      + + ++++ ++L++++la  ++      dn++ i

Q: 448   GIWNVMSSQEVVDFIQAKISqrdengELRLLSSIVEELLDQCLAPDTSgdgtgcDNMTCI  507

         ****************99998777666666788999999999999998777777777766

S: 259   v  259

Q: 508   I  508

Domain Sequence
(FASTA)

GSDSGTTAVV ALIRGKQLIV ANAGDSRCVV SEAGKALDMS YDHKPEDELE LARIKNAGGK 60

VTMDGRVNGG LNLSRAIGDH FYKRNKNLPP EEQMISALPD IKVLTLNEDH DFMVIACDGI 120

WNVMSSQEVV DFIQAKISQR DENGELRLLS SIVEELLDQC LAPDTSGDGT GCDNMTCII 179

Keyword

Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005634	; C:nucleus
GO:0046872	; F:metal ion binding
GO:0004722	; F:protein serine/threonine phosphatase activity
GO:0007050	; P:cell cycle arrest
GO:0035970	; P:peptidyl-threonine dephosphorylation

KEGG

InterPros

IPR001932	; PP2C-like.
IPR000222	; PP2C_Mn2_Asp60_BS.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481

; PP2C; 2.

SMARTs

SM00331	; PP2C_SIG; 1.
SM00332	; PP2Cc; 1.

Prosites

PS01032

; PP2C; 1.

Prints

Created Date

20-Feb-2013