EKS-MOD-00476

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00476

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	373.4	6.3E-112	44	298	255

Status

Unreviewed

Ensembl Protein

ENSMODP00000019548

UniProt Accession

F7EIH3;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK4

Gene Synonyms/Alias

CAMK4;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000015662	ENSMODP00000019548	ENSMODT00000019897

Organism

Monodelphis domestica

Functional Description

Protein Length

425

Protein Sequence
(FASTA)

MLKVTAPTSS SSSCSTVPTA TGGTSAATDY WIDGSNKDSL NDFFEVETEL GRGATSVVYR 60

CMQKGTQKPY ALKVLKKTVD KKIIRTEIGV LLRLSHPNII KLKEIFETQT EISLVLELVT 120

GGELFDRIVE KGYYSERDAA QAVKQILEAV AYLHENGIVH RDLKPENLLY ATPDPDAPLK 180

IADFGLSKIV EDQVTMKTIC GTPGYCAPEI LRGCAYGPEV DMWSLGVITY ILLCGFEPFY 240

DERGDPYMYK RILNCHYRFV SPWWDDVSLN AKDLVRKLIV LDPKKRLTTF QALQHPWVTG 300

KAANFVHMDT AQKKLQEFNA RRKLKAAVKA VVASTRLGGG SGHSCLSVTC KTSKPDEESE 360

SKQNETRKEE SEFVFAVTGA QLEEEIRDKV EPGIEPRPQA EYFAPEEALR VAGEEEIQQW 420

FPIQG 425

Nucleotide Sequence
(FASTA)

ATGCTGAAAG TCACCGCGCC CACCTCCTCT TCCTCTTCTT GTTCCACCGT ACCCACCGCT 60

ACTGGGGGCA CCTCCGCTGC TACCGATTAC TGGATCGACG GCTCCAATAA AGACTCTTTG 120

AACGATTTCT TCGAGGTGGA GACGGAGCTG GGACGGGGTG CTACATCAGT TGTGTACAGA 180

TGTATGCAGA AGGGGACCCA GAAACCTTAT GCTCTCAAAG TGCTAAAGAA AACAGTAGAC 240

AAAAAAATAA TTCGGACTGA AATAGGTGTC CTTCTTCGCC TTTCACATCC AAACATCATA 300

AAACTAAAAG AGATATTTGA AACACAAACA GAAATCAGCC TGGTTTTGGA ATTGGTCACA 360

GGAGGAGAAC TGTTTGATAG AATTGTGGAA AAAGGCTATT ACAGTGAGCG GGATGCTGCC 420

CAAGCTGTTA AGCAAATCCT GGAGGCAGTT GCGTATCTAC ATGAAAATGG AATTGTTCAT 480

CGTGATCTTA AACCTGAGAA TCTTCTCTAT GCAACTCCAG ACCCAGATGC ACCACTCAAA 540

ATAGCTGATT TTGGACTTTC TAAAATTGTG GAGGATCAAG TTACCATGAA GACTATATGC 600

GGAACCCCAG GATATTGTGC ACCTGAAATT CTTAGAGGAT GTGCCTATGG ACCTGAAGTG 660

GATATGTGGT CCCTGGGAGT AATCACCTAC ATCTTACTTT GTGGATTTGA ACCATTCTAT 720

GATGAAAGGG GCGATCCGTA CATGTATAAG AGAATTCTGA ACTGTCACTA TCGCTTTGTC 780

TCCCCCTGGT GGGATGATGT GTCTCTGAAT GCCAAGGATT TGGTGAGGAA ACTGATTGTT 840

TTGGATCCTA AGAAGCGTTT GACCACCTTT CAAGCTCTGC AGCACCCTTG GGTCACAGGG 900

AAAGCAGCTA ATTTTGTACA CATGGACACT GCCCAAAAGA AACTCCAAGA ATTCAATGCA 960

CGGAGAAAGC TTAAGGCTGC AGTGAAAGCA GTGGTGGCCT CCACCCGACT GGGGGGTGGT 1020

AGTGGTCACA GCTGCCTTTC TGTCACCTGT AAGACTTCAA AACCAGATGA AGAAAGTGAG 1080

AGTAAACAAA ATGAAACTCG GAAGGAAGAG AGCGAGTTTG TGTTTGCAGT AACAGGAGCC 1140

CAACTTGAAG AAGAAATAAG AGACAAAGTG GAACCTGGAA TAGAACCTCG TCCTCAAGCA 1200

GAATACTTTG CTCCAGAAGA AGCCCTAAGA GTGGCTGGAG AGGAAGAAAT ACAACAGTGG 1260

TTCCCAATAC AGGGCTGA 1278

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         ++++++lG+Ga+s v+++ +k tqk++a+kv+kk+    +++ +++ei vl +l+hpni+

Q: 44    FEVETELGRGATSVVYRCMQKGTQKPYALKVLKKTV---DKKIIRTEIGVLLRLSHPNII  100

         78999*****************************98...89*******************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         +lk+i+e++++++lvlelvtGGelfdrivekg+y+e+da++ +kq+leav+ylhe+givh

Q: 101   KLKEIFETQTEISLVLELVTGGELFDRIVEKGYYSERDAAQAVKQILEAVAYLHENGIVH  160

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly++++ d+++kiadfGlsk+ e++  +kt cGt+gy+ape+l+ ++y+ +v

Q: 161   RDLKPENLLYATPDPDAPLKIADFGLSKIVEDQvTMKTICGTPGYCAPEILRGCAYGPEV  220

         ****************************88888689************************

S: 180   dvWsiGvityillcGyppfydekeekl.lekilkgeyefesPyWdeisesakdfikklle  238

         d+Ws+GvityillcG++pfyde+ + +  ++il+++y+f sP+Wd++s +akd+++kl+

Q: 221   DMWSLGVITYILLCGFEPFYDERGDPYmYKRILNCHYRFVSPWWDDVSLNAKDLVRKLIV  280

         ***********************88763799*****************************

S: 239   ldpekrytieqaledpWi  256

         ldp+kr+t+ qal++pW+

Q: 281   LDPKKRLTTFQALQHPWV  298

         *****************7

Domain Sequence
(FASTA)

FEVETELGRG ATSVVYRCMQ KGTQKPYALK VLKKTVDKKI IRTEIGVLLR LSHPNIIKLK 60

EIFETQTEIS LVLELVTGGE LFDRIVEKGY YSERDAAQAV KQILEAVAYL HENGIVHRDL 120

KPENLLYATP DPDAPLKIAD FGLSKIVEDQ VTMKTICGTP GYCAPEILRG CAYGPEVDMW 180

SLGVITYILL CGFEPFYDER GDPYMYKRIL NCHYRFVSPW WDDVSLNAKD LVRKLIVLDP 240

KKRLTTFQAL QHPWV 255

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0007616	; P:long-term memory
GO:0043011	; P:myeloid dendritic cell differentiation
GO:0007270	; P:neuron-neuron synaptic transmission
GO:0006913	; P:nucleocytoplasmic transport
GO:0046827	; P:positive regulation of protein export from nucleus
GO:0045893	; P:positive regulation of transcription, DNA-dependent
GO:0007165	; P:signal transduction

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013