EKS-MOD-00255

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00255

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	244.0	1.6E-72	792	1044	253

Status

Unreviewed

Ensembl Protein

ENSMODP00000019969

UniProt Accession

F7EYX0;

Protein Name

Protein Synonyms/Alias

Gene Name

PASK

Gene Synonyms/Alias

PASK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000016002	ENSMODP00000019969	ENSMODT00000020326

Organism

Monodelphis domestica

Functional Description

Protein Length

1069

Protein Sequence
(FASTA)

MSLKIFLEDG CIYAPTGFFL LGNIDIPFEE NCFNLNRLYP RVFQHLGRKN GFTRLCKSRM 60

SLSEDKWSTY CLSSLAAQNI CSSRFNIMPH SEHSDLTGSI CSTSYCSLVN SLPSRSSIHS 120

IGSSVYAPNR AIFILDLKTM MILVVNDQAC ELLGYSSNEL IGQPFSLIFS KPSTVIEEAL 180

SNECGETDGP NVIAFGTVVD IVCSNKEKIP VSIWMKKLEH GPCCVALLEP VERFTVWVTF 240

QSDGKIISCD NLFTQLFGYA SLEEVVGREI MDLIPSLQMP PPGQLVSEAL KIQKLTGRTK 300

DGNTFPLSLK LRSEALCKEE EEGQPEPSVF IYSASLWIFT TISGLITLLP DGTIYGINHN 360

FALTLFGYEK EEVLGKNITF LIPDFYNYMD LIENSSVPTL NITNPVDRRN ENKTGKGREG 420

GKQKWNQADG TEDPGVNILH SANEFQQILE EDKKASGPLR FPSKIEVLGE NDGNSSPSSF 480

LPLEEISTPG VDSPPTQEEQ PLPMRAPEEE HAETRMVPGQ DASGSQKSLT GILKKEHSAQ 540

SKGDPKKLNS VVILEQSTFQ SKVLDSSSAS DPKENTSSVG PAITEGTRDE VHSSEKHLVS 600

ETLDPQTTLL PNADEQKRSA GVEDIQGGSA PEDTSVAHTP PGYNINPLAD TLGKQTLNAQ 660

ATSTPMKLGK EQIPRISLQM EILEGTYTGS CYHRDGTKLN IQFELRHVEL KGPADLFCCW 720

VVKDFFPSSR QGLAGRTQCL FSSLNASSHS LLEESRMGPS EFRKQKEVIE EFFQSKDLGV 780

LKAYEGDYSK RYTTVRPIGS GAFGFVWIAK SKEDGTEVVV KFIKKEKVLE DCWVTDPALG 840

KVTQEIAILS QLSHPNIIKV VDVFENEEFF QLVMEKHGSG MDLFSFIDSH PTLDEPLASY 900

IFRQVVAAVT YLRSKNITHR DIKDENIIIG EDFTIKLVDF GSAVYMEPGK YFYTFCGTIE 960

YCSPEVLMGH AYSGPELEMW ALGVTLYTLM FEENPFNELD EALEAILNPP FLVSPELLNL 1020

LCGLLHPQPE KRLTLDLVIQ HTWVTQPVNL ANYSWEEVCH VTIESECSI 1069

Nucleotide Sequence
(FASTA)

ATGTCCTTGA AGATTTTCCT GGAAGATGGC TGTATATATG CACCAACGGG ATTTTTCTTA 60

TTGGGAAATA TAGACATTCC ATTTGAAGAA AACTGCTTCA ACCTGAACAG ACTTTATCCC 120

AGGGTTTTCC AGCACCTGGG CAGGAAGAAT GGCTTTACTA GACTTTGTAA GAGTAGAATG 180

TCACTTTCAG AAGACAAATG GAGCACCTAT TGTTTGTCTT CCCTGGCTGC CCAGAATATT 240

TGTTCAAGCC GATTCAACAT CATGCCCCAT TCAGAGCACT CGGACCTGAC GGGCTCCATA 300

TGTAGCACAT CCTATTGCTC CTTAGTGAAT AGCTTGCCTT CGAGGTCATC CATTCACTCC 360

ATTGGCTCAT CTGTGTATGC CCCCAATAGA GCCATATTCA TATTGGATTT GAAGACAATG 420

ATGATTCTTG TTGTCAATGA CCAAGCTTGT GAGCTCCTTG GATATTCCAG TAACGAGCTG 480

ATTGGCCAGC CCTTTTCATT GATCTTCTCT AAACCCAGCA CTGTGATAGA AGAGGCATTA 540

AGTAATGAGT GTGGTGAGAC TGATGGACCA AATGTCATTG CTTTTGGAAC AGTGGTGGAC 600

ATTGTCTGCT CCAATAAGGA GAAGATTCCT GTCTCCATCT GGATGAAGAA GTTGGAACAT 660

GGTCCCTGCT GTGTTGCTTT GCTGGAGCCC GTGGAGAGAT TTACGGTTTG GGTCACTTTC 720

CAGAGTGATG GCAAGATAAT ATCATGTGAT AACCTTTTTA CTCAACTCTT TGGCTATGCG 780

TCCTTGGAAG AAGTGGTTGG AAGAGAAATA ATGGACCTCA TTCCTTCGCT CCAGATGCCT 840

CCCCCAGGCC AGCTGGTCTC AGAGGCTCTC AAGATTCAGA AATTGACTGG GAGAACCAAG 900

GATGGGAACA CCTTCCCTCT GAGTTTGAAG CTGAGGTCCG AGGCACTATG TAAGGAAGAA 960

GAAGAGGGTC AGCCAGAACC TTCAGTTTTT ATTTACTCAG CTTCTCTTTG GATTTTTACC 1020

ACCATTAGTG GTTTAATCAC GCTTCTGCCT GATGGCACCA TCTATGGCAT CAACCACAAT 1080

TTTGCTCTAA CATTGTTTGG TTATGAGAAG GAAGAGGTGC TGGGAAAGAA CATCACATTT 1140

CTGATACCTG ATTTCTACAA CTATATGGAC CTCATAGAAA ATAGCTCTGT CCCAACGCTC 1200

AATATCACTA ACCCCGTGGA CAGAAGAAAT GAGAATAAGA CTGGGAAAGG GAGAGAAGGC 1260

GGCAAACAGA AGTGGAATCA AGCAGATGGA ACTGAAGATC CTGGTGTTAA TATCTTGCAT 1320

TCTGCAAATG AATTTCAGCA AATCTTAGAG GAAGACAAGA AAGCCTCAGG ACCCTTAAGA 1380

TTCCCCAGTA AGATTGAGGT CCTAGGTGAA AATGATGGGA ACAGTTCGCC TTCTTCTTTT 1440

TTACCCCTTG AAGAAATATC CACACCAGGT GTAGATAGTC CCCCCACCCA AGAGGAACAG 1500

CCCTTGCCTA TGAGAGCACC TGAAGAAGAA CATGCAGAGA CCAGGATGGT GCCAGGTCAA 1560

GATGCTTCTG GCAGTCAAAA GAGCCTAACT GGTATCTTAA AAAAGGAACA TAGTGCTCAG 1620

TCTAAAGGAG ATCCTAAAAA ACTGAATTCA GTTGTTATTT TGGAACAATC CACTTTCCAA 1680

TCAAAGGTCT TGGATTCTTC CTCTGCTTCT GATCCAAAAG AAAATACCTC CTCAGTGGGC 1740

CCAGCTATTA CTGAAGGCAC AAGGGATGAA GTGCACTCCT CTGAGAAGCA TCTTGTGTCT 1800

GAGACGTTAG ACCCCCAGAC AACCCTTCTG CCTAATGCGG ACGAGCAGAA GCGGAGTGCT 1860

GGTGTAGAGG ACATCCAGGG AGGATCAGCT CCAGAGGATA CCAGTGTAGC CCACACTCCT 1920

CCAGGCTATA ATATCAATCC CTTGGCAGAC ACTTTAGGAA AGCAAACACT GAATGCTCAA 1980

GCAACTTCCA CTCCTATGAA ACTGGGAAAG GAACAGATCC CTAGAATTAG TCTCCAAATG 2040

GAAATCCTGG AAGGCACTTA CACTGGGAGC TGTTATCATA GAGATGGCAC CAAGCTCAAC 2100

ATACAGTTCG AGCTGCGGCA CGTGGAGTTA AAGGGGCCTG CAGATTTGTT CTGCTGTTGG 2160

GTGGTGAAAG ACTTCTTCCC AAGCTCTCGG CAGGGACTGG CAGGAAGAAC TCAGTGTCTG 2220

TTTTCCAGCT TGAATGCCTC CTCGCACTCG TTACTGGAAG AGTCCAGGAT GGGCCCCAGC 2280

GAATTCAGAA AACAAAAAGA AGTGATCGAG GAATTCTTTC AGAGTAAAGA CTTGGGAGTC 2340

CTGAAGGCTT ACGAGGGCGA CTACTCGAAG CGCTACACCA CTGTCAGGCC CATCGGCAGC 2400

GGCGCCTTTG GCTTCGTTTG GATTGCCAAG AGTAAGGAAG ACGGCACCGA GGTTGTGGTC 2460

AAGTTTATTA AGAAGGAGAA GGTGCTGGAA GACTGCTGGG TGACAGATCC CGCGCTGGGA 2520

AAAGTGACCC AAGAGATTGC CATCCTCTCG CAGCTGAGTC ATCCCAACAT CATTAAGGTG 2580

GTGGACGTGT TCGAAAATGA AGAATTTTTC CAGTTAGTGA TGGAGAAACA TGGATCTGGC 2640

ATGGATCTCT TCTCCTTCAT TGACAGCCAT CCTACTCTGG ACGAGCCCCT GGCGAGCTAC 2700

ATATTTAGAC AAGTGGTGGC GGCAGTGACG TACCTTCGCT CAAAAAACAT CACCCATCGA 2760

GACATTAAGG ATGAGAACAT CATCATTGGG GAGGACTTCA CGATTAAGCT GGTGGACTTT 2820

GGCTCCGCTG TTTACATGGA ACCTGGCAAA TATTTCTACA CTTTCTGCGG CACCATCGAG 2880

TACTGCTCCC CAGAAGTTCT CATGGGCCAC GCCTACAGTG GCCCAGAGCT GGAGATGTGG 2940

GCCCTTGGGG TAACCCTCTA TACTTTAATG TTTGAAGAGA ATCCTTTCAA TGAGCTGGAT 3000

GAAGCCCTGG AGGCAATACT GAACCCTCCC TTTTTGGTCT CCCCTGAGCT TTTGAACCTT 3060

CTCTGTGGGC TATTGCACCC CCAACCAGAA AAGCGCTTGA CCTTGGACTT GGTGATCCAG 3120

CACACTTGGG TGACCCAGCC TGTGAACTTG GCGAACTATT CCTGGGAGGA AGTGTGTCAC 3180

GTAACCATAG AATCAGAATG TAGCATTTAG 3210

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkkl......seeslekikrEieilkk  54

         y++++ +G+g+fg V  ak+ke +++v+vK+ikk+k+      ++ +l k+++Ei+il++

Q: 792   YTTVRPIGSGAFGFVWIAKSKEDGTEVVVKFIKKEKVledcwvTDPALGKVTQEIAILSQ  851

         88999*******************************99888888888*************

S: 55    lkhpniikllevietkkklylvle.yasggeLfdyieekgrlkekearklfkqlvsavkY  113

         l+hpniik+++v+e++++++lv+e + sg +Lf+ i ++ +l+e  a+ +f+q+v+av+Y

Q: 852   LSHPNIIKVVDVFENEEFFQLVMEkHGSGMDLFSFIDSHPTLDEPLASYIFRQVVAAVTY  911

         ************************889999******************************

S: 114   lhskgivHrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkk  173

         l+sk+i+HrD+K eN+++ ++ +ik++DFG a ++++gk + tfcG+++Y++Pe+l+g+

Q: 912   LRSKNITHRDIKDENIIIGEDFTIKLVDFGSAVYMEPGKYFYTFCGTIEYCSPEVLMGHA  971

         ************************************************************

S: 174   YegpkvDvWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklL  233

         Y+gp++++W+lGv+Ly+l++++ Pf+e       ++ l+  l+ p+ +s+el +Ll  lL

Q: 972   YSGPELEMWALGVTLYTLMFEENPFNEL------DEALEAILNPPFLVSPELLNLLCGLL  1025

         *************************998......4556666778899*************

S: 234   vvdpekRatieeilkhewl  252

         + +pekR+t++ + +h+w+

Q: 1026  HPQPEKRLTLDLVIQHTWV  1044

         ******************7

Domain Sequence
(FASTA)

YTTVRPIGSG AFGFVWIAKS KEDGTEVVVK FIKKEKVLED CWVTDPALGK VTQEIAILSQ 60

LSHPNIIKVV DVFENEEFFQ LVMEKHGSGM DLFSFIDSHP TLDEPLASYI FRQVVAAVTY 120

LRSKNITHRD IKDENIIIGE DFTIKLVDFG SAVYMEPGKY FYTFCGTIEY CSPEVLMGHA 180

YSGPELEMWA LGVTLYTLMF EENPFNELDE ALEAILNPPF LVSPELLNLL CGLLHPQPEK 240

RLTLDLVIQH TWV 253

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013