EKS-MOD-00067

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00067

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	349.3	1.6E-104	52	336	285

Status

Unreviewed

Ensembl Protein

ENSMODP00000020405

UniProt Accession

F7FL41;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK15

Gene Synonyms/Alias

CDK15;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000016326	ENSMODP00000020405	ENSMODT00000020764

Organism

Monodelphis domestica

Functional Description

Protein Length

384

Protein Sequence
(FASTA)

MTSLYPKESH ASQARKLRSK RPRSNSDSFQ EKDLEQSFPW RKSLPFGAAS SYLNLEKLGE 60

GTYATVYKGI SRINGQLVAL KVISMNTEEG VPFTAIREAS LLKGLKHANI VLLHDIIHTK 120

ETLTFVFEYM HTDLAQYMSQ HPGGLHPHNV RLFMFQLLRG LAYIHHQHIL HRDLKPQNLL 180

ISYLGELKLA DFGLARAKSI PSQTYSSEVV TLWYRPPDAL LGATEYSSDL DIWGAGCIFI 240

EMLQGQPLFP GVSDILEQLE KIWEVLGVPT EDTWPGVSKL PNYNPEWFLL SKPQGLQVVW 300

NRLGKIPGAE DLASRMLRGF PRDRVSAQEA LAHDYFNVLP AELHQLPDVE SLFTVPGVRL 360

KPEICNLFAS YQRSHHSARF SKCW 384

Nucleotide Sequence
(FASTA)

ATGACATCAC TGTACCCCAA GGAATCACAT GCATCCCAGG CCCGGAAATT GAGGAGTAAA 60

AGGCCAAGGA GCAACAGTGA TTCTTTCCAA GAAAAGGACC TTGAACAAAG TTTTCCATGG 120

AGGAAGAGCC TTCCTTTTGG AGCTGCCTCA TCATACCTGA ATTTGGAAAA ATTAGGTGAA 180

GGCACTTATG CCACAGTCTA CAAGGGGATC AGCCGGATAA ATGGTCAACT CGTGGCTTTA 240

AAAGTCATCA GCATGAATAC TGAGGAAGGG GTACCCTTCA CAGCCATTCG AGAAGCCTCC 300

CTCCTGAAGG GTTTGAAGCA TGCCAATATT GTGCTCCTGC ATGACATTAT CCACACCAAA 360

GAGACCCTGA CTTTTGTTTT TGAATACATG CATACTGATC TGGCCCAGTA TATGTCTCAA 420

CATCCAGGAG GTCTTCATCC TCACAATGTC AGGCTCTTCA TGTTTCAACT TTTGAGGGGC 480

CTGGCTTACA TCCACCATCA ACACATTCTT CACCGGGATC TGAAACCTCA GAACTTACTC 540

ATCAGTTATC TGGGAGAACT CAAATTAGCT GATTTTGGTC TTGCTCGGGC CAAGTCCATC 600

CCCAGTCAGA CATACTCTTC GGAAGTAGTG ACACTCTGGT ATCGTCCTCC AGATGCATTG 660

CTAGGAGCCA CAGAATATTC CTCTGATTTG GATATCTGGG GTGCAGGCTG CATCTTTATT 720

GAAATGCTCC AGGGTCAACC TTTGTTTCCT GGAGTTTCTG ATATTCTTGA ACAACTAGAA 780

AAGATCTGGG AGGTATTGGG GGTCCCTACT GAGGATACTT GGCCTGGAGT TTCCAAGCTA 840

CCTAACTACA ATCCAGAGTG GTTCCTGCTG AGTAAGCCCC AAGGTCTCCA GGTCGTCTGG 900

AACAGGTTGG GCAAGATTCC AGGAGCTGAA GACTTGGCCT CTCGAATGCT CAGAGGCTTC 960

CCACGAGATC GGGTCTCTGC CCAAGAAGCT CTCGCCCATG ATTATTTCAA TGTCCTACCA 1020

GCTGAGCTAC ACCAGCTTCC AGATGTGGAG TCTTTGTTTA CAGTGCCAGG AGTGAGACTA 1080

AAACCAGAAA TCTGTAATCT CTTTGCCTCT TACCAGAGAA GTCATCACTC AGCTCGATTC 1140

AGCAAGTGCT GGTGA 1155

Domain Profile

S: 1     yeklekigeGtygkvykakdketgevvAlKkirlekekegvpitalrEisllkelkhkni  60

         y +lek+geGty++vyk+ ++ +g++vAlK i +++e egvp+ta+rE sllk lkh+ni

Q: 52    YLNLEKLGEGTYATVYKGISRINGQLVALKVISMNTE-EGVPFTAIREASLLKGLKHANI  110

         6789******************************999.9*********************

S: 61    vkLlevvakdkkklyLvfefleqdLkkllkkkkkkklsleevkslllqlleglaylHsnk  120

         v L+++++ +k++l++vfe++++dL++++++++  +l++++v+ +++qll+glay+H+++

Q: 111   VLLHDIIH-TKETLTFVFEYMHTDLAQYMSQHPG-GLHPHNVRLFMFQLLRGLAYIHHQH  168

         ********.99***********************.*************************

S: 121   ilHRDlKpqNlLiskegklklaDfGlarafssplktytkevvTlwYraPelLlgakeYst  180

         ilHRDlKpqNlLis  g+lklaDfGlara s p++ty++evvTlwYr+P+ Llga+eYs+

Q: 169   ILHRDLKPQNLLISYLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS  228

         ************************************************************

S: 181   avDiWsvgcilaelltrkplfqgkse.idqlerifkllgtpsekvwpevsklpeyk.ksf  238

         ++DiW++gci+ e+l+ +plf+g s+  +qle+i+++lg p+e++wp+vsklp+y+ + f

Q: 229   DLDIWGAGCIFIEMLQGQPLFPGVSDiLEQLEKIWEVLGVPTEDTWPGVSKLPNYNpEWF  288

         *************************967****************************8889

S: 239   pkkkkkklkekvkklkek..aldllekllaldpkkRisakealqhkyf  284

           +k++ l+ ++++l +   a dl +++l+  p++R+sa+eal+h+yf

Q: 289   LLSKPQGLQVVWNRLGKIpgAEDLASRMLRGFPRDRVSAQEALAHDYF  336

         999999******9999655589*************************9

Domain Sequence
(FASTA)

YLNLEKLGEG TYATVYKGIS RINGQLVALK VISMNTEEGV PFTAIREASL LKGLKHANIV 60

LLHDIIHTKE TLTFVFEYMH TDLAQYMSQH PGGLHPHNVR LFMFQLLRGL AYIHHQHILH 120

RDLKPQNLLI SYLGELKLAD FGLARAKSIP SQTYSSEVVT LWYRPPDALL GATEYSSDLD 180

IWGAGCIFIE MLQGQPLFPG VSDILEQLEK IWEVLGVPTE DTWPGVSKLP NYNPEWFLLS 240

KPQGLQVVWN RLGKIPGAED LASRMLRGFP RDRVSAQEAL AHDYF 285

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013