EKS-MOD-00416

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00416

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/WEE	315.6	2.6E-94	101	349	249

Status

Unreviewed

Ensembl Protein

ENSMODP00000034567

UniProt Accession

F7F1V1;

Protein Name

Protein Synonyms/Alias

Gene Name

PKMYT1

Gene Synonyms/Alias

PKMYT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000016524	ENSMODP00000034567	ENSMODT00000036155

Organism

Monodelphis domestica

Functional Description

Protein Length

495

Protein Sequence
(FASTA)

MPVPTEGAPP PLSGTPVPVP AYFRHAEPGF SLKRPGGLNR SLPPRPPAKG SGSVSRFFPP 60

RTPGWSQPRP RGVSFRGGPP GALQSRGYDP DRPESFFQQS FQRLGRLGRG SFGEVFKVRS 120

KEDGRLYAVK RSVSPFRGPQ DRALKLAEVG GHEKVGRHPR CVRLERAWEE GGLLYLQTEL 180

CGPNLQQHCE ARGSGLPEAQ VWGYLRDTLL ALAHLHSHGL AHLDVKPANI FLGPRGRCKL 240

GDFGLLVELG TAGPGEAQEG DPRYMAPELL QGCYGTAADV FSLGLTILEV ACNMELPRGG 300

EGWQQLRRGY LPPEFTAGLS SELRSVLIMM LEPDPKKRAT AESLLALEVI RKLRHWGPLE 360

GMVNEVLSRG RALWQSFLSL LCWLWHTLAH PASWLRPLGP PATPPSSPLS SLLLDSSISS 420

DWEDDSLGPP LSPAMILARS PGGTSTPRNG SPDVRGGRRI RDPLDLSGIS PELPQGPSFE 480

PRNLLSLFED SLDPN 495

Nucleotide Sequence
(FASTA)

ATGCCAGTTC CAACAGAAGG GGCCCCTCCA CCCCTGAGTG GTACTCCTGT GCCTGTTCCT 60

GCATACTTTC GTCATGCTGA GCCTGGCTTC TCACTTAAGA GGCCTGGGGG CCTGAATCGA 120

AGCCTCCCCC CAAGGCCCCC TGCCAAGGGG AGTGGTTCTG TCAGTCGTTT CTTTCCCCCT 180

CGTACCCCAG GCTGGAGCCA ACCCCGACCC AGAGGAGTTT CATTCCGGGG TGGGCCCCCA 240

GGAGCATTGC AGAGCCGTGG CTATGATCCA GACCGGCCTG AGTCTTTCTT CCAGCAGAGT 300

TTCCAGAGGC TTGGGAGATT GGGACGGGGT TCCTTTGGGG AGGTCTTCAA GGTTCGCTCC 360

AAGGAAGATG GCCGTCTCTA TGCTGTGAAA CGTTCAGTCT CCCCATTCCG GGGTCCTCAG 420

GACCGGGCCC TCAAGTTGGC AGAAGTTGGG GGTCATGAAA AAGTGGGGCG GCATCCCCGT 480

TGTGTACGTC TGGAGAGAGC TTGGGAAGAG GGTGGGCTCC TGTATTTGCA GACAGAGCTG 540

TGTGGGCCCA ATCTACAACA ACACTGTGAG GCTCGGGGGT CTGGCCTACC TGAGGCCCAG 600

GTTTGGGGTT ATCTTCGGGA CACATTACTG GCCTTGGCAC ACCTACACAG CCATGGACTG 660

GCACACTTGG ACGTCAAGCC AGCTAACATC TTCTTGGGGC CTCGAGGCCG CTGCAAGTTG 720

GGAGACTTTG GACTGTTGGT GGAGCTGGGG ACTGCTGGGC CTGGTGAGGC CCAAGAGGGT 780

GATCCCCGTT ATATGGCTCC TGAGCTGCTA CAAGGTTGCT ATGGGACAGC TGCAGACGTG 840

TTCAGCTTGG GCCTTACCAT TCTGGAAGTC GCCTGCAACA TGGAGCTGCC CCGTGGTGGG 900

GAGGGCTGGC AGCAACTCCG GAGAGGCTAT CTGCCCCCTG AATTCACTGC TGGCCTGTCC 960

TCCGAGCTGC GCTCTGTCCT TATCATGATG CTAGAACCAG ACCCCAAGAA GCGTGCCACA 1020

GCTGAATCCC TGCTGGCCCT GGAGGTCATA AGGAAGCTGA GGCACTGGGG GCCCCTGGAA 1080

GGCATGGTCA ATGAGGTCCT GAGTCGAGGT CGAGCCTTGT GGCAAAGTTT CCTTTCTCTG 1140

CTATGCTGGC TATGGCACAC CTTGGCTCAC CCGGCCAGCT GGCTCCGCCC CTTGGGCCCT 1200

CCAGCCACGC CCCCCAGCTC CCCACTCTCC AGCCTCCTTC TAGACAGCAG CATCTCCAGT 1260

GACTGGGAGG ATGACAGCTT GGGCCCCCCA CTGTCTCCAG CAATGATCCT AGCCCGCTCC 1320

CCTGGGGGTA CTTCTACCCC TCGAAATGGT TCCCCTGATG TCAGAGGTGG ACGGAGAATA 1380

AGGGACCCCC TGGACTTAAG TGGCATCAGC CCGGAGCTGC CCCAGGGTCC TTCCTTTGAG 1440

CCCCGAAACC TCCTCAGCCT CTTTGAGGAC TCACTTGACC CCAACTGA 1488

Domain Profile

S: 1     FeevekiGkGefgevfkvvkredgklyAikkskkplkglskekkalrEvtahavlgqhen  60

         F+++ ++G+G+fgevfkv+++edg+lyA+k+s +p++g ++++ +l+Ev +h+++g+h+

Q: 101   FQRLGRLGRGSFGEVFKVRSKEDGRLYAVKRSVSPFRGPQDRALKLAEVGGHEKVGRHPR  160

         89999*******************************************************

S: 61    vvryisaWeeddslyiqtElCeggsLeaalqeceakkkaleeaelkkilldlllglrylH  120

         +vr+ +aWee + ly+qtElC g +L+++   cea  + l+ea+++ +l d ll+l +lH

Q: 161   CVRLERAWEEGGLLYLQTELC-GPNLQQH---CEARGSGLPEAQVWGYLRDTLLALAHLH  216

         *********************.*******...****************************

S: 121   ssslvHlDikpenifitkevtlklgDlGlvtelnsedkskveEGDsrylakEilqeeysk  180

         s+ l HlD+kp+nif+  ++++klgD+Gl++el+++   +++EGD ry+a+E+lq++y +

Q: 217   SHGLAHLDVKPANIFLGPRGRCKLGDFGLLVELGTAGPGEAQEGDPRYMAPELLQGCYGT  276

         ************************************************************

S: 181   lkaDiFslgltilevaanvelPsnGeaWhklRkgklpdeilkelsedlrellklmlepdp  240

         + aD+Fslgltileva+n+elP+ Ge W++lR+g+lp+e+++ ls++lr++l +mlepdp

Q: 277   A-ADVFSLGLTILEVACNMELPRGGEGWQQLRRGYLPPEFTAGLSSELRSVLIMMLEPDP  335

         *.**********************************************************

S: 241   erRptaeellkhev  254

         ++R+tae+ll+ ev

Q: 336   KKRATAESLLALEV  349

         **********9887

Domain Sequence
(FASTA)

FQRLGRLGRG SFGEVFKVRS KEDGRLYAVK RSVSPFRGPQ DRALKLAEVG GHEKVGRHPR 60

CVRLERAWEE GGLLYLQTEL CGPNLQQHCE ARGSGLPEAQ VWGYLRDTLL ALAHLHSHGL 120

AHLDVKPANI FLGPRGRCKL GDFGLLVELG TAGPGEAQEG DPRYMAPELL QGCYGTAADV 180

FSLGLTILEV ACNMELPRGG EGWQQLRRGY LPPEFTAGLS SELRSVLIMM LEPDPKKRAT 240

AESLLALEV 249

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0010923	; P:negative regulation of phosphatase activity

KEGG

mdo:100618653

;

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013