EKS-MOD-00472

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00472

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMK1	446.9	2.3E-134	23	279	257

Status

Unreviewed

Ensembl Protein

ENSMODP00000021011

UniProt Accession

F6R272;

Protein Name

Protein Synonyms/Alias

Gene Name

CAMK1D

Gene Synonyms/Alias

CAMK1D;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000016833	ENSMODP00000021011	ENSMODT00000021381

Organism

Monodelphis domestica

Functional Description

Protein Length

392

Protein Sequence
(FASTA)

MARENGESSS SWKKQAEDIK KIFEFKETLG TGAFSEVVLA EEKATGKLFA VKCIPKKALK 60

GKESSIENEI AVLRKIKHEN IVALEDIYES PNHLYLVMQL VSGGELFDRI VEKGFYTEKD 120

ASTLIRQVLD AVYYLHRMGI VHRDLKPENL LYYSQDEESK IMISDFGLSK MEGKGDVMST 180

ACGTPGYVAP EVLAQKPYSK AVDCWSIGVI AYILLCGYPP FYDENDSKLF EQILKAEYEF 240

DSPYWDDISD SAKDFIRNLM EKDPNKRYTC EQAARHPWIA GDTALCKNIH ESVSAQIRKN 300

FAKSKWRQAF NATAVVRHMR KLHLGSSLDS SNSSVSSSLS LASQHPDGTT RKDCLASSTL 360

CSFISSSSGV SAVGAERRPR PTTVTTVHTG SK 392

Nucleotide Sequence
(FASTA)

ATGGCCCGGG AGAACGGGGA GAGCAGCTCC TCCTGGAAAA AGCAAGCAGA GGACATCAAG 60

AAGATTTTCG AGTTCAAGGA GACCCTGGGA ACTGGTGCAT TTTCTGAAGT GGTTTTAGCT 120

GAAGAGAAAG CAACTGGAAA ACTTTTTGCA GTGAAATGTA TCCCGAAGAA GGCACTAAAA 180

GGCAAAGAAA GCAGCATAGA GAATGAAATT GCTGTTCTGA GAAAAATTAA ACACGAAAAT 240

ATCGTTGCTC TGGAAGATAT TTACGAAAGT CCAAACCACT TATACTTGGT TATGCAACTT 300

GTATCTGGCG GGGAGCTTTT TGATCGAATA GTGGAGAAAG GATTTTACAC TGAAAAAGAT 360

GCCAGTACTC TAATCCGCCA GGTTTTGGAT GCTGTCTACT ATCTCCACAG GATGGGTATC 420

GTACATAGGG ACCTCAAGCC TGAAAACCTT TTGTACTACA GCCAGGATGA GGAGTCCAAA 480

ATCATGATCA GTGACTTTGG GTTGTCCAAA ATGGAAGGTA AAGGAGATGT CATGTCTACA 540

GCATGTGGCA CTCCAGGATA TGTAGCTCCA GAAGTCCTTG CACAGAAACC TTATAGTAAA 600

GCAGTTGACT GCTGGTCCAT CGGCGTGATT GCTTATATAT TGCTCTGCGG TTATCCTCCC 660

TTCTATGATG AAAATGACTC CAAACTTTTT GAGCAGATTC TCAAGGCAGA ATATGAATTT 720

GACTCTCCCT ATTGGGATGA CATCTCAGAT TCTGCTAAAG ATTTCATTCG GAATTTGATG 780

GAGAAAGATC CCAATAAAAG ATATACATGT GAGCAGGCAG CTCGGCACCC CTGGATTGCT 840

GGTGATACAG CCCTTTGCAA AAATATCCAT GAGTCTGTCA GTGCCCAGAT CCGGAAGAAC 900

TTTGCAAAAA GCAAATGGAG ACAAGCATTC AATGCCACAG CCGTCGTGAG GCATATGAGA 960

AAACTGCATC TCGGCAGCAG CCTTGACAGT TCAAACTCAA GTGTGTCAAG CAGCCTCAGC 1020

CTGGCCAGCC AACACCCTGA TGGGACAACC CGAAAAGATT GCCTGGCATC CTCCACACTC 1080

TGTAGTTTTA TTTCCTCCTC TTCGGGTGTC TCTGCAGTAG GAGCTGAGCG GAGACCGAGG 1140

CCAACCACTG TGACCACAGT CCATACTGGC AGCAAGTGA 1179

Domain Profile

S: 1     yklkeklGeGafsevlkakekktqkavaikvikkkalkgkeesveneiavlkklkhpniv  60

         +++ke+lG+Gafsev++a+ek+t+k +a+k+i kkalkgke+s+eneiavl+k+kh+niv

Q: 23    FEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIV  82

         799*********************************************************

S: 61    alkdiyesksklylvlelvtGGelfdrivekgvytekdasevikqvleavkylhelgivh  120

         al+diyes+++lylv++lv+GGelfdrivekg+ytekdas++i+qvl+av ylh++givh

Q: 83    ALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVH  142

         ************************************************************

S: 121   rdlkPenllylskeedskikiadfGlskleeke.llktacGtvgyvapevlkqkkyskkv  179

         rdlkPenlly+s++e+ski+i+dfGlsk+e k+ +++tacGt+gyvapevl+qk+ysk+v

Q: 143   RDLKPENLLYYSQDEESKIMISDFGLSKMEGKGdVMSTACGTPGYVAPEVLAQKPYSKAV  202

         ********************************99**************************

S: 180   dvWsiGvityillcGyppfydekeekllekilkgeyefesPyWdeisesakdfikkllel  239

         d+WsiGvi+yillcGyppfyde+++kl+e+ilk+eyef+sPyWd+is+sakdfi++l+e+

Q: 203   DCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEK  262

         ************************************************************

S: 240   dpekrytieqaledpWi  256

         dp+kryt+eqa ++pWi

Q: 263   DPNKRYTCEQAARHPWI  279

         ****************8

Domain Sequence
(FASTA)

FEFKETLGTG AFSEVVLAEE KATGKLFAVK CIPKKALKGK ESSIENEIAV LRKIKHENIV 60

ALEDIYESPN HLYLVMQLVS GGELFDRIVE KGFYTEKDAS TLIRQVLDAV YYLHRMGIVH 120

RDLKPENLLY YSQDEESKIM ISDFGLSKME GKGDVMSTAC GTPGYVAPEV LAQKPYSKAV 180

DCWSIGVIAY ILLCGYPPFY DENDSKLFEQ ILKAEYEFDS PYWDDISDSA KDFIRNLMEK 240

DPNKRYTCEQ AARHPWI 257

Keyword

ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0005634	; C:nucleus
GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity
GO:0032793	; P:positive regulation of CREB transcription factor activity
GO:0010976	; P:positive regulation of neuron projection development
GO:0090023	; P:positive regulation of neutrophil chemotaxis
GO:0050766	; P:positive regulation of phagocytosis
GO:0060267	; P:positive regulation of respiratory burst
GO:0042981	; P:regulation of apoptotic process
GO:0050773	; P:regulation of dendrite development
GO:0071622	; P:regulation of granulocyte chemotaxis

KEGG

mdo:100011530

;

InterPros

IPR020636	; Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013