EKS-MOD-00070

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00070

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDK	320.0	1.4E-95	26	335	310

Status

Unreviewed

Ensembl Protein

ENSMODP00000022354

UniProt Accession

F7EKB4;

Protein Name

Protein Synonyms/Alias

Gene Name

CDK19

Gene Synonyms/Alias

CDK19;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000017926	ENSMODP00000022354	ENSMODT00000022744

Organism

Monodelphis domestica

Functional Description

Protein Length

508

Protein Sequence
(FASTA)

MDYDFKAKLA AERERVEDLF EYEGCKVGRG TYGHVYKARR KDGKDEKEYA LKQIEGTGIS 60

MSACREIALL RELKHPNVIA LQKVFLSHSD RKVWLLFDYA EHDLWHIIKF PRAPKANKKP 120

MQLPRTMGKT PLYQNLEGNH YLHANWVLHR DLKPANILVM GEGPERGRVK IADMGFARLF 180

NSPLKPLADL DPVVVTFWYR APELLLGARH YTKAIDIWAI GCIFAELLTS EPIFHCRQED 240

IKTSNPFHHD QLDRIFSVMG FPADKDWEDI RKMPEYPTLQ KDFRRTTYAN SSLIKYMEKH 300

KVKPDSKVFL LLQKLLTMDP TKRITSEQAL QDPYFQEDPL PTSDVFAGCQ IPYPKREFLN 360

EDEPEEKGDK NQQQQNQHQQ QTAPQQPQQA VPPPPPPQPQ PQQQQQQQNN TQTNGTAAGA 420

GGGGTGAGLQ HSQDSGLNPV PPNKKPRLGP AGTNSGGPVM PSEYQHSSSR LSYQSNVQGS 480

SQSQSTMGYS TSSQQSSQYH PAHQAHRY 508

Nucleotide Sequence
(FASTA)

ATGGATTATG ACTTTAAGGC GAAGCTGGCG GCCGAGCGGG AGCGGGTGGA GGATCTGTTT 60

GAGTACGAGG GATGTAAAGT GGGACGCGGC ACCTACGGTC ACGTCTACAA GGCCAGGCGG 120

AAAGATGGAA AAGATGAAAA GGAATATGCA TTGAAGCAAA TTGAAGGCAC AGGAATATCC 180

ATGTCGGCTT GTAGAGAGAT TGCACTTTTA CGGGAATTGA AGCACCCTAA TGTGATTGCA 240

TTACAAAAGG TGTTCCTTTC TCACAGTGAC AGAAAGGTTT GGCTGCTATT TGATTATGCA 300

GAACATGATT TATGGCACAT CATTAAGTTT CCCCGGGCCC CCAAAGCAAA TAAAAAACCA 360

ATGCAGTTGC CAAGAACAAT GGGTAAAACA CCGCTTTACC AGAATCTTGA GGGAAACCAT 420

TACCTCCATG CAAACTGGGT GCTTCACAGA GACTTGAAAC CAGCAAATAT CCTAGTAATG 480

GGAGAAGGCC CGGAAAGGGG GAGAGTCAAA ATAGCTGACA TGGGTTTTGC CAGATTATTC 540

AATTCTCCCT TAAAACCTTT AGCAGACTTG GATCCAGTAG TAGTGACATT TTGGTATCGA 600

GCTCCAGAAC TGTTGCTTGG TGCAAGGCAT TATACAAAGG CCATTGATAT ATGGGCAATT 660

GGTTGTATAT TTGCTGAACT ATTGACTTCA GAACCTATTT TTCACTGTCG TCAGGAAGAT 720

ATCAAAACAA GCAATCCTTT TCATCATGAT CAACTAGATC GTATTTTTAG TGTCATGGGA 780

TTCCCTGCAG ATAAAGACTG GGAAGATATT AGAAAAATGC CAGAATATCC CACACTTCAA 840

AAAGACTTTA GAAGAACAAC GTATGCCAAT AGTAGCCTCA TAAAATACAT GGAAAAACAC 900

AAAGTCAAGC CTGACAGCAA AGTTTTCCTT TTGCTTCAGA AACTTCTTAC TATGGATCCC 960

ACAAAGAGAA TTACCTCAGA ACAAGCATTG CAGGATCCTT ATTTCCAAGA GGATCCCCTA 1020

CCTACATCAG ATGTGTTTGC TGGCTGTCAG ATTCCATATC CCAAACGAGA ATTTCTTAAT 1080

GAGGATGAAC CTGAAGAAAA AGGTGACAAG AATCAGCAGC AGCAAAATCA GCATCAGCAA 1140

CAAACAGCAC CTCAGCAGCC ACAGCAGGCA GTGCCACCGC CACCACCACC ACAGCCACAG 1200

CCACAGCAGC AGCAACAGCA ACAAAACAAC ACCCAGACCA ATGGAACAGC AGCAGGAGCA 1260

GGAGGAGGGG GTACTGGGGC AGGGCTCCAG CACAGCCAGG ACTCAGGCCT TAATCCAGTG 1320

CCTCCAAATA AGAAACCACG GCTAGGTCCT GCAGGCACTA ACTCAGGCGG GCCTGTTATG 1380

CCTTCTGAAT ATCAGCACTC CAGTTCACGC CTGAGTTACC AAAGCAATGT TCAGGGATCG 1440

TCTCAGTCCC AGAGTACCAT GGGCTATTCC ACGTCATCTC AGCAGAGCTC CCAGTACCAT 1500

CCTGCTCACC AGGCTCACCG GTACTGA 1527

Domain Profile

S: 6     kigeGtygkvykakdke..tgevvAlKkirlekekegvpitalrEisllkelkhknivkL  63

         k+g+Gtyg+vyka++k+  +++ +AlK+i    e +g++++a+rEi+ll+elkh+n++ L

Q: 26    KVGRGTYGHVYKARRKDgkDEKEYALKQI----EGTGISMSACREIALLRELKHPNVIAL  81

         79************986436678******....999************************

S: 64    levva.kdkkklyLvfefleqdLkkllkkkkkk.......klsleevkslllqlleglay  115

         ++v+  ++++k++L+f+++e+dL++++k  ++        +l++++ k+ l+q leg +y

Q: 82    QKVFLsHSDRKVWLLFDYAEHDLWHIIKFPRAPkankkpmQLPRTMGKTPLYQNLEGNHY  141

         ****94555*******************998877888999999999**************

S: 116   lHsnkilHRDlKpqNlLiske....gklklaDfGlarafssplk...tytkevvTlwYra  168

         lH+n++lHRDlKp+N+L++ e    g++k+aD+G+ar f+splk   +++++vvT+wYra

Q: 142   LHANWVLHRDLKPANILVMGEgperGRVKIADMGFARLFNSPLKplaDLDPVVVTFWYRA  201

         *******************9988889*************99999665699**********

S: 169   PelLlgakeYstavDiWsvgcilaelltrkplfqgkse.........idqlerifkllgt  219

         PelLlga++Y++a+DiW++gci+aellt++p+f++++e         +dql+rif+++g

Q: 202   PELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEdiktsnpfhHDQLDRIFSVMGF  261

         ************************************************************

S: 220   psekvwpevsklpeyk...ksfpkkkkk..klkekvkklk....ekaldllekllaldpk  270

         p +k+w++++k+pey    k+f+++++   +l ++++k k    +k + ll+kll++dp+

Q: 262   PADKDWEDIRKMPEYPtlqKDFRRTTYAnsSLIKYMEKHKvkpdSKVFLLLQKLLTMDPT  321

         ***************965457777666544666666443333545689************

S: 271   kRisakealqhkyf  284

         kRi++++alq++yf

Q: 322   KRITSEQALQDPYF  335

         *************9

Domain Sequence
(FASTA)

KVGRGTYGHV YKARRKDGKD EKEYALKQIE GTGISMSACR EIALLRELKH PNVIALQKVF 60

LSHSDRKVWL LFDYAEHDLW HIIKFPRAPK ANKKPMQLPR TMGKTPLYQN LEGNHYLHAN 120

WVLHRDLKPA NILVMGEGPE RGRVKIADMG FARLFNSPLK PLADLDPVVV TFWYRAPELL 180

LGARHYTKAI DIWAIGCIFA ELLTSEPIFH CRQEDIKTSN PFHHDQLDRI FSVMGFPADK 240

DWEDIRKMPE YPTLQKDFRR TTYANSSLIK YMEKHKVKPD SKVFLLLQKL LTMDPTKRIT 300

SEQALQDPYF 310

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Cavia porcellus"; ?>Drosophila melanogaster"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Oreochromis niloticus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Schizosaccharomyces pombe"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013