EKS-MOD-00201

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00201

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/RCK	518.4	5.0E-156	4	284	281

Status

Unreviewed

Ensembl Protein

ENSMODP00000023457

UniProt Accession

F6Z040;

Protein Name

Protein Synonyms/Alias

Gene Name

ICK

Gene Synonyms/Alias

ICK;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000018808	ENSMODP00000023457	ENSMODT00000023873

Organism

Monodelphis domestica

Functional Description

Protein Length

632

Protein Sequence
(FASTA)

MHRYTTIKQL GDGTYGSVLL GRSIESGELI AIKKMKRKFY SWEECMNLRE VKSLKKLNHA 60

NVVKLKEVIR ENDHLYFVFE YMKENLYQLM KERNKLFPES AIRNIMYQIL QGLAFIHKHG 120

FFHRDLKPEN LLCMGPELVK IADFGLAREI RSRPPYTDYV STRWYRAPEV LLRSTNYSSP 180

IDIWAVGCIM AEVYTLRPLF PGASEIDTIF KICQVLGTPK KNDWPEGYQL SSSMNFRWPQ 240

CIPNNLKSLI PNASSEAIQL MRDMLQWDPK KRPTASQALR YPYFQVGHPL GSTPHSLQEP 300

GKPQKEFHEK MGPPPHMKPV PPAHPPAKPQ PRISSRAHQP SQPPQHLIYP YKTEASPADP 360

ESQLPGDQPH PVHFPALHNK IPQTKILAGM EHPNGEIKPK SRRRWGPVSR STKDSDDWDD 420

LDDFDFNPSL TRTDLKNKKR QSDETLCRFE SVLDLKPSEP IGTGNSAPTH TSYQRQDTPT 480

LRSVAKQHYL KHSRYLPGIP IRNGILPNPG KDFLPPNSWS GSSLSGKSSG SISEISRMNS 540

VVSGYLGSSR LTSGYFPSFL KKEVGSAGQR VHLAPISDPP PGYASLKSVR PHHNRPLFHT 600

QPRSTPGLLP RPPAAQPVHG RTDWVSKYAS RR 632

Nucleotide Sequence
(FASTA)

ATGCATCGAT ACACGACCAT CAAGCAGCTC GGCGACGGAA CCTACGGCTC TGTGCTCCTA 60

GGAAGAAGTA TCGAGTCTGG AGAGCTGATC GCCATTAAGA AGATGAAAAG AAAGTTCTAT 120

TCTTGGGAGG AATGTATGAA TCTTCGAGAG GTCAAGTCTT TAAAGAAGCT CAACCATGCC 180

AATGTAGTGA AATTGAAAGA AGTCATCAGG GAAAATGATC ATCTTTATTT TGTCTTTGAA 240

TACATGAAAG AAAACCTGTA TCAGCTAATG AAAGAAAGAA ACAAGTTGTT TCCTGAGTCA 300

GCTATTAGGA ATATCATGTA TCAGATACTA CAGGGACTTG CATTCATCCA CAAACATGGT 360

TTCTTCCACA GAGACTTAAA ACCTGAAAAC CTCCTTTGCA TGGGACCAGA ACTTGTGAAA 420

ATAGCTGACT TTGGATTAGC CAGAGAAATC CGATCAAGAC CACCTTATAC AGACTATGTG 480

TCTACAAGAT GGTATCGGGC TCCAGAAGTT CTCTTGAGGT CTACCAACTA CAGTTCTCCT 540

ATTGACATCT GGGCGGTGGG ATGCATCATG GCAGAAGTTT ACACGCTACG GCCGCTCTTC 600

CCAGGTGCCA GTGAAATTGA TACGATATTC AAAATTTGCC AAGTGCTGGG AACACCAAAA 660

AAGAATGACT GGCCCGAAGG ATATCAGCTT TCTAGTTCCA TGAACTTCCG TTGGCCTCAG 720

TGTATCCCTA ATAATTTAAA GAGCCTGATT CCAAATGCCA GCAGTGAGGC AATTCAGCTC 780

ATGAGGGACA TGTTGCAGTG GGATCCCAAA AAGCGACCAA CAGCTAGTCA GGCGCTTCGA 840

TATCCCTACT TTCAGGTGGG ACATCCCCTG GGCAGCACTC CCCATAGCCT TCAGGAACCG 900

GGGAAGCCGC AGAAAGAATT CCACGAGAAG ATGGGACCTC CGCCACACAT GAAGCCCGTC 960

CCTCCTGCGC ACCCGCCTGC CAAGCCGCAG CCCCGGATTT CTTCTCGAGC CCACCAGCCC 1020

AGCCAGCCCC CGCAACATCT CATCTACCCG TACAAAACGG AGGCTTCCCC AGCCGACCCT 1080

GAGAGCCAGC TCCCGGGGGA CCAGCCTCAT CCCGTACATT TCCCAGCCCT CCACAACAAG 1140

ATTCCTCAGA CTAAAATTCT GGCTGGCATG GAGCACCCAA ACGGTGAAAT AAAACCAAAG 1200

AGTAGGAGAA GGTGGGGTCC TGTTTCCAGG TCAACTAAAG ATTCTGATGA TTGGGATGAT 1260

TTAGATGACT TCGATTTCAA CCCTTCCCTC ACCAGGACTG ATCTAAAAAA TAAGAAAAGA 1320

CAGAGCGATG AAACTCTCTG TAGATTTGAG AGTGTTTTGG ACCTGAAGCC TTCAGAGCCC 1380

ATAGGTACTG GCAACAGTGC ACCCACCCAC ACTTCCTATC AACGACAAGA CACCCCAACA 1440

TTGCGATCTG TAGCCAAGCA GCATTACTTG AAACACTCCA GATACTTGCC TGGAATACCT 1500

ATTAGAAATG GTATACTTCC AAATCCAGGC AAGGATTTTC TTCCACCTAA TTCATGGTCT 1560

GGTTCTAGTC TGTCTGGAAA ATCTTCAGGG TCCATATCAG AAATCAGCAG AATGAATTCA 1620

GTTGTTTCAG GCTATTTAGG ATCCAGCAGA CTGACTAGTG GCTATTTCCC TTCATTTCTG 1680

AAAAAAGAAG TGGGTTCTGC TGGACAGAGG GTACACCTAG CTCCTATTTC AGATCCTCCT 1740

CCTGGTTACG CTTCGCTGAA GTCTGTGAGA CCTCATCATA ATCGCCCCCT TTTCCATACC 1800

CAGCCCAGAA GTACCCCGGG ATTATTGCCA CGGCCCCCTG CAGCCCAGCC TGTCCATGGA 1860

CGTACTGACT GGGTTTCTAA GTATGCATCT AGACGATGA 1899

Domain Profile

S: 1     yklikklGdGtfgevllakslktgelvaikkmkrkfesleevtnlrevkslkklnahdni  60

         y++ik+lGdGt+g+vll++s+++gel+aikkmkrkf+s+ee++nlrevkslkkln h+n+

Q: 4     YTTIKQLGDGTYGSVLLGRSIESGELIAIKKMKRKFYSWEECMNLREVKSLKKLN-HANV  62

         99*****************************************************.****

S: 61    iklkeviidrendslylvlelmeenlyqlikdrrkllsesklksilyqilkglafihkhg  120

         +klkevi  rend+ly+v+e+m+enlyql+k+r+kl++es++++i+yqil+glafihkhg

Q: 63    VKLKEVI--RENDHLYFVFEYMKENLYQLMKERNKLFPESAIRNIMYQILQGLAFIHKHG  120

         *******..***************************************************

S: 121   ffhrdlkPenilikgselvkladfGlarevrsknPytdyvstrwyraPevllrsgvyssp  180

         ffhrdlkPen+l++g+elvk+adfGlare+rs++PytdyvstrwyraPevllrs++yssp

Q: 121   FFHRDLKPENLLCMGPELVKIADFGLAREIRSRPPYTDYVSTRWYRAPEVLLRSTNYSSP  180

         ************************************************************

S: 181   ldlwavGcvlaevavlrplfPGaseidqifkilevlGtPkkkewdeayklasalnlkfpq  240

         +d+wavGc++aev++lrplfPGaseid+ifki++vlGtPkk++w+e+y+l+s++n+++pq

Q: 181   IDIWAVGCIMAEVYTLRPLFPGASEIDTIFKICQVLGTPKKNDWPEGYQLSSSMNFRWPQ  240

         ************************************************************

S: 241   vegsslktlvsnaskealellkdllaydPderataqqalkypyf  284

         +++++lk+l++nas+ea++l++d+l++dP++r+ta+qal+ypyf

Q: 241   CIPNNLKSLIPNASSEAIQLMRDMLQWDPKKRPTASQALRYPYF  284

         *******************************************9

Domain Sequence
(FASTA)

YTTIKQLGDG TYGSVLLGRS IESGELIAIK KMKRKFYSWE ECMNLREVKS LKKLNHANVV 60

KLKEVIREND HLYFVFEYMK ENLYQLMKER NKLFPESAIR NIMYQILQGL AFIHKHGFFH 120

RDLKPENLLC MGPELVKIAD FGLAREIRSR PPYTDYVSTR WYRAPEVLLR STNYSSPIDI 180

WAVGCIMAEV YTLRPLFPGA SEIDTIFKIC QVLGTPKKND WPEGYQLSSS MNFRWPQCIP 240

NNLKSLIPNA SSEAIQLMRD MLQWDPKKRP TASQALRYPY F 281

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Saccharomyces cerevisiae"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013