EPS-MOD-00016

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MOD-00016

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/aDSP	62.8	3.3E-17	330	423	94

Status

Unreviewed

Ensembl Protein

ENSMODP00000024846

UniProt Accession

F6VPI0;

Protein Name

Protein Synonyms/Alias

Gene Name

PTPMT1

Gene Synonyms/Alias

PTPMT1;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000019914	ENSMODP00000024846	ENSMODT00000025287

Organism

Monodelphis domestica

Functional Description

Protein Length

432

Protein Sequence
(FASTA)

MTEGMISTDS ASSKPKGHPV AGSTSRENRL PVMKTFREIF TTQWSERPRQ CELGPGVPLR 60

QSPLTPPLPR SLPSVAGVQA INFISPVAFL PRYWPAGLPE SLGFSRRASP LDRRHAAAAG 120

GGAVPFPGPA PMPPMPPPSL PSRAVSTPPL LAPTPAAGKD NSLKPSLLSL LPGTSSTSSE 180

HSRETVRRAK EGESLRTTIW GRCRSRRTAR NYDPKTPSQS PESSQGPGPT SSSWGSNGMA 240

TAVLGAGLAR ILFYPTLLYT LVRDKVSGPG HRDWYNRIDA TVLLGALPLR SLTRRLVEEE 300

NVRGVITMNE EYETRFLCNT YEEWKATGVE QLRLSTVDMT GVPTLENLKK GVRFTLEYTE 360

QGKCVYIHCK AGRSRSATMV AAYLMKVYNC SPEEAIKAIA KIRSHIHVRS RQVEVLKEFY 420

KELLAEAEKS KA 432

Nucleotide Sequence
(FASTA)

ATGACAGAAG GGATGATTTC AACAGATTCT GCAAGTTCAA AGCCAAAGGG CCACCCCGTG 60

GCCGGTTCCA CCTCCCGAGA AAACAGGCTC CCCGTAATGA AGACCTTCCG GGAAATCTTC 120

ACGACCCAGT GGAGTGAGCG GCCAAGGCAA TGTGAGCTGG GCCCTGGAGT ACCCTTGAGG 180

CAGAGTCCGT TAACTCCTCC TCTCCCTAGG TCTTTGCCTT CAGTGGCGGG CGTCCAGGCC 240

ATCAATTTCA TTTCGCCCGT CGCCTTCCTG CCTCGCTATT GGCCCGCGGG TCTACCAGAG 300

TCCCTCGGGT TCTCCCGGCG GGCCTCCCCA TTGGACAGAC GGCATGCGGC TGCTGCGGGG 360

GGCGGGGCCG TTCCTTTTCC GGGTCCCGCC CCCATGCCGC CGATGCCCCC CCCCTCCCTC 420

CCCTCCAGGG CCGTCTCCAC GCCCCCCTTG CTGGCCCCTA CCCCGGCCGC CGGCAAGGAC 480

AACTCGCTGA AGCCGAGTCT GCTGTCGTTG CTCCCGGGCA CATCATCGAC CAGCTCCGAG 540

CATAGCAGGG AGACGGTGCG GAGGGCGAAG GAGGGGGAGT CGCTGAGGAC CACTATCTGG 600

GGTCGCTGCA GGAGCCGGCG CACCGCCCGG AACTACGATC CGAAGACCCC GAGCCAGTCT 660

CCAGAGTCAA GCCAGGGCCC GGGCCCGACG TCCTCGAGCT GGGGCTCCAA CGGCATGGCC 720

ACGGCGGTGC TGGGCGCCGG CCTGGCGCGG ATCCTCTTCT ACCCGACGCT GCTGTACACG 780

CTGGTGCGCG ACAAGGTGTC GGGCCCGGGA CACCGCGACT GGTACAACCG CATCGACGCC 840

ACCGTGCTGC TGGGCGCACT GCCGCTGCGC AGCCTCACGC GCCGGCTGGT AGAGGAGGAG 900

AATGTCCGGG GAGTGATCAC CATGAATGAA GAATATGAAA CAAGATTCCT GTGTAACACT 960

TATGAGGAAT GGAAAGCAAC TGGAGTAGAG CAATTGCGTC TCAGCACAGT GGATATGACT 1020

GGGGTCCCAA CTTTGGAAAA CCTAAAGAAA GGCGTACGCT TTACTCTAGA ATACACGGAA 1080

CAGGGGAAAT GTGTCTATAT TCATTGCAAG GCTGGGCGCT CCAGAAGTGC CACCATGGTG 1140

GCAGCCTATT TGATGAAGGT ATACAACTGT AGCCCAGAAG AGGCTATAAA AGCTATCGCC 1200

AAGATCCGCT CCCACATCCA TGTCCGATCG AGGCAGGTAG AGGTCCTCAA GGAATTCTAC 1260

AAAGAGCTCT TGGCTGAAGC AGAAAAATCT AAGGCTTGA 1299

Domain Profile

S: 54    tyknipvdDsdvtdllqyfdeaaefideakekggkvlvHCaaGvsRSatlvlaYLmkveg  113

         + +++   D      l+ +++ ++f  e +e+g+ v++HC+aG sRSat+v aYLmkv++

Q: 330   EQLRLSTVDMTGVPTLENLKKGVRFTLEYTEQGKCVYIHCKAGRSRSATMVAAYLMKVYN  389

         55555555555666677778888999999*******************************

S: 114   lslsdAieavkrkrpsiepnegfleQLlelekkl  147

          s ++Ai+a+ + r++i  ++ ++e L e+ k+l

Q: 390   CSPEEAIKAIAKIRSHIHVRSRQVEVLKEFYKEL  423

         ***************************9998876

Domain Sequence
(FASTA)

EQLRLSTVDM TGVPTLENLK KGVRFTLEYT EQGKCVYIHC KAGRSRSATM VAAYLMKVYN 60

CSPEEAIKAI AKIRSHIHVR SRQVEVLKEF YKEL 94

Keyword

Complete proteome; Hydrolase; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Gadus morhua"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0004725	; F:protein tyrosine phosphatase activity
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0035335	; P:peptidyl-tyrosine dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR024950	; DUSP.
IPR000387	; Tyr/Dual-specificity_Pase.
IPR016130	; Tyr_Pase_AS.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS00383	; TYR_PHOSPHATASE_1; 1.
PS50056	; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013