EKS-MOD-00251

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MOD-00251

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/CAMKL	309.8	1.3E-92	73	324	252

Status

Unreviewed

Ensembl Protein

ENSMODP00000025370

UniProt Accession

F7C0G7;

Protein Name

Protein Synonyms/Alias

Gene Name

LOC100012988

Gene Synonyms/Alias

LOC100012988;

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMODG00000020280	ENSMODP00000025370	ENSMODT00000025821

Organism

Monodelphis domestica

Functional Description

Protein Length

435

Protein Sequence
(FASTA)

MTTVCVNGGL GNPRYARWNH RESIEDCGWT ERYQGDVEGS PHRLTPFEKL TQDMSKDEKV 60

VREITLGKRI GFYRVRGEIG SGNFSQVKLG IHSLTKEKVA IKILDKTKLD QKTQRLLSRE 120

ISTMEKLHHP NIIRLYEVVE TLSKLHLVME YAGGGELFLK ISTEGKLSET ESKLIFSQIV 180

SAVKHMHENQ IIHRDLKAEN VFYTSNMCVK VGDFGFSTIS KKGETLNTFC GSPPYAAPEL 240

FRDENYVGIY VDIWALGVLL YFMVTGTMPF RAETVAKLKK CILDGTYSIP PDVSNPCQRL 300

IRGVLQPIPT ERYGIDYIMH NEWMQGVLHP TPLEPFQLDP QYLSEKSTLK EEENEVKSTL 360

ENLGITEEHI RNNGRDSRSS ITGVYRIILH RVQRRRALES VPIVTLPDPK EGEPKKASRR 420

VYRGIRHTSK FCSIL 435

Nucleotide Sequence
(FASTA)

ATGACCACAG TTTGTGTGAA TGGAGGCCTG GGGAACCCCC GCTATGCCAG ATGGAATCAC 60

CGGGAGAGCA TTGAAGACTG TGGCTGGACT GAGCGCTACC AGGGAGATGT GGAAGGGTCG 120

CCGCACAGGC TGACGCCATT TGAGAAACTC ACTCAAGACA TGTCAAAGGA TGAGAAGGTG 180

GTGAGAGAAA TCACACTTGG GAAAAGGATT GGCTTCTACC GGGTTCGAGG GGAAATTGGA 240

AGTGGAAACT TCTCCCAAGT GAAGCTTGGA ATTCACTCCC TAACCAAAGA AAAGGTGGCT 300

ATTAAGATCC TGGACAAGAC CAAGTTAGAC CAGAAAACCC AAAGGCTACT GTCACGGGAG 360

ATCTCCACCA TGGAGAAACT GCATCACCCC AACATCATCC GCCTCTATGA AGTTGTTGAG 420

ACCCTGTCTA AGCTCCACCT GGTGATGGAG TACGCTGGAG GCGGAGAGCT CTTCCTGAAG 480

ATCAGCACCG AGGGGAAGCT CTCAGAAACC GAAAGCAAGC TCATTTTCTC CCAGATTGTG 540

TCCGCTGTGA AGCACATGCA TGAAAATCAA ATCATTCATA GAGATCTGAA GGCTGAAAAT 600

GTATTTTATA CAAGCAATAT GTGTGTGAAG GTGGGCGATT TTGGATTCAG CACAATAAGC 660

AAAAAAGGTG AAACACTGAA CACTTTCTGT GGGTCTCCTC CATATGCTGC CCCAGAGCTC 720

TTCCGGGATG AAAATTATGT GGGCATTTAT GTGGACATCT GGGCTTTGGG GGTCCTCTTA 780

TATTTTATGG TGACTGGCAC CATGCCATTT CGAGCGGAGA CCGTGGCCAA ACTGAAGAAG 840

TGTATCCTCG ATGGGACATA CAGTATACCT CCTGATGTCT CCAACCCCTG TCAGAGGCTG 900

ATCCGAGGGG TCCTGCAGCC AATACCCACA GAAAGGTATG GAATTGACTA CATTATGCAC 960

AACGAATGGA TGCAAGGGGT GCTACACCCC ACTCCCTTGG AACCCTTCCA ACTAGATCCC 1020

CAGTATTTAT CAGAAAAAAG CACACTTAAG GAAGAAGAGA ATGAGGTCAA GAGCACCTTA 1080

GAAAATCTGG GTATTACTGA AGAGCATATT AGAAATAACG GAAGAGATTC CCGCAGCTCA 1140

ATCACGGGGG TCTACCGTAT TATTCTGCAC CGAGTCCAAA GAAGAAGGGC TTTAGAGAGT 1200

GTTCCTATAG TGACCCTGCC AGACCCCAAG GAAGGAGAAC CCAAGAAAGC ATCCCGTCGT 1260

GTCTACCGGG GCATACGACA CACATCCAAA TTTTGTTCAA TTTTATAA 1308

Domain Profile

S: 1     ykllktlGegsfgkVklakhketkekvavKiikkkklseeslekikrEieilkklkhpni  60

         y++  ++G+g+f++Vkl +h++tkekva+Ki++k+kl++++++ ++rEi++++kl+hpni

Q: 73    YRVRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISTMEKLHHPNI  132

         89999*******************************************************

S: 61    ikllevietkkklylvleyasggeLfdyieekgrlkekearklfkqlvsavkYlhskgiv  120

         i+l+ev+et +kl+lv+eya ggeLf +i+++g+l+e+e++ +f+q+vsavk++h+++i+

Q: 133   IRLYEVVETLSKLHLVMEYAGGGELFLKISTEGKLSETESKLIFSQIVSAVKHMHENQII  192

         ************************************************************

S: 121   HrDlKpeNllldkkenikiaDFGlanlfkegklletfcGsppYaaPellkgkkYegpkvD  180

         HrDlK+eN++ ++++ +k+ DFG++++ k+g++l+tfcGsppYaaPel+++++Y g  vD

Q: 193   HRDLKAENVFYTSNMCVKVGDFGFSTISKKGETLNTFCGSPPYAAPELFRDENYVGIYVD  252

         ************************************************************

S: 181   vWslGvvLyalvtgklPfdeenlkellekilkgkleipkklskelesLlrklLvvdpekR  240

         +W+lGv+Ly++vtg++Pf++e++++l++ il+g+++ip  +s+ +++L+r +L+  p++R

Q: 253   IWALGVLLYFMVTGTMPFRAETVAKLKKCILDGTYSIPPDVSNPCQRLIRGVLQPIPTER  312

         ************************************************************

S: 241   atieeilkhewl  252

         + i+ i+++ew+

Q: 313   YGIDYIMHNEWM  324

         ***********8

Domain Sequence
(FASTA)

YRVRGEIGSG NFSQVKLGIH SLTKEKVAIK ILDKTKLDQK TQRLLSREIS TMEKLHHPNI 60

IRLYEVVETL SKLHLVMEYA GGGELFLKIS TEGKLSETES KLIFSQIVSA VKHMHENQII 120

HRDLKAENVF YTSNMCVKVG DFGFSTISKK GETLNTFCGS PPYAAPELFR DENYVGIYVD 180

IWALGVLLYF MVTGTMPFRA ETVAKLKKCI LDGTYSIPPD VSNPCQRLIR GVLQPIPTER 240

YGIDYIMHNE WM 252

Keyword

ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Dipodomys ordii"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Mus musculus"; ?>Mustela putorius furo"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0000287	; F:magnesium ion binding
GO:0004674	; F:protein serine/threonine kinase activity

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.
IPR017441	; Protein_kinase_ATP_BS.
IPR002290	; Ser/Thr_dual-sp_kinase_dom.
IPR008271	; Ser/Thr_kinase_AS.

Pfam

PF00069

; Pkinase; 1.

SMARTs

SM00220

; S_TKc; 1.

Prosites

PS00107	; PROTEIN_KINASE_ATP; 1.
PS50011	; PROTEIN_KINASE_DOM; 1.
PS00108	; PROTEIN_KINASE_ST; 1.

Prints

Created Date

20-Feb-2013