EKS-MUP-00482

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00482

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TKL/RIPK	353.9	5.4E-106	14	281	268

Status

Unreviewed

Ensembl Protein

ENSMPUP00000000449

Gene Name

RIPK1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000000454	ENSMPUP00000000449	ENSMPUT00000000459

Organism

Mustela putorius furo

Protein Length

646

Protein Sequence
(FASTA)

MSLDDIKMKT SDLLEKEYLD SGGFGKVSLC LHRCHGLVIL KKVYTGPKRT EYNESLLEEG 60

KMMHRLRHSR VVKLLGVIIE EGNYSLVMEY MEKGNLMHVL KAEVSIPLSL KGRIIMEIIE 120

GMCYLHGQGI IHKDLKPENI LVDDDFHIKI ADLGVASFKM WSKLTKEEHN EQRKLNRVSK 180

KNGGTLCYMA PEHLNDINAK PSEKSDVYSF GIVLWAIFAN KEPYENAICE EQLIICIKSG 240

NRPNVEDILE YCPEEIISIM KQCWEAKPDI RPTFIGLEEK FRPFYVDQLE ENVEDDVTSL 300

KKQYPDPDQS SFVKRMHSLQ IDCTAIPPSR SNSAPEQPSS LHSSQGLGIG PVEESWFAPS 360

LENQQEENQL SLQSKLQEEA NYHLHGSRMD RQTKPLRQNV IYNREEERRR RVSHDPFAQP 420

KPYENVQNPG VGLPYSSATS PGNALHQPTG PTSQPQVLYW NNGLNNPFSF GTRPQDLGAA 480

SSRAWYGPNP NHMPSVHKTP VPETNLLGNT ATLSFGSFPS RDESVKCSIR NSAGIQIGDH 540

NYMEISGMSS VPLDMNFKEE PAAKYHDIFE NITSLTDKHL DPVRENLGKQ WKNCARKLGF 600

TEPQIDEIDH DYERDGLKEK VYQMLQKWQM REGQPCLYCS RNSNGQ 646

Nucleotide Sequence
(FASTA)

ATGTCCTTGG ATGACATTAA GATGAAAACT AGTGACTTAC TGGAGAAGGA GTACCTGGAC 60

AGCGGGGGTT TCGGAAAGGT GTCTCTGTGT TTACACAGAT GCCATGGACT CGTAATACTG 120

AAAAAGGTGT ACACGGGCCC CAAGCGCACT GAGTACAACG AGTCCCTCCT TGAGGAGGGC 180

AAGATGATGC ACAGGCTGAG ACATAGTCGG GTGGTGAAGC TGCTGGGCGT CATCATAGAA 240

GAAGGGAACT ACTCCCTGGT GATGGAGTAC ATGGAAAAGG GCAACCTGAT GCACGTTCTG 300

AAGGCGGAGG TCAGCATCCC CCTTTCTCTA AAAGGAAGGA TAATTATGGA GATCATTGAA 360

GGGATGTGCT ACTTACATGG ACAAGGCATA ATACACAAGG ACCTAAAGCC TGAAAATATC 420

CTCGTTGATG ATGACTTTCA CATTAAGATA GCTGATCTTG GTGTTGCTTC CTTTAAGATG 480

TGGAGTAAAC TGACTAAAGA GGAACATAAC GAGCAGAGGA AATTGAATCG AGTCTCTAAG 540

AAAAACGGTG GAACCCTTTG CTACATGGCC CCTGAGCATC TGAATGACAT CAACGCAAAG 600

CCCTCAGAGA AGTCAGATGT GTACAGCTTT GGCATAGTAC TTTGGGCAAT ATTTGCTAAT 660

AAGGAGCCCT ACGAAAATGC GATCTGTGAA GAGCAGTTGA TAATATGCAT TAAATCTGGG 720

AACAGGCCAA ATGTGGAAGA CATCCTTGAA TACTGCCCAG AGGAGATAAT TAGCATCATG 780

AAGCAGTGCT GGGAGGCGAA ACCAGACATT CGACCAACAT TTATTGGCCT TGAAGAAAAA 840

TTTAGGCCTT TTTATGTAGA TCAATTAGAA GAAAATGTAG AAGACGATGT GACAAGTTTA 900

AAGAAACAGT ATCCAGACCC AGACCAGAGT TCATTTGTGA AGAGAATGCA TTCTCTCCAG 960

ATTGACTGTA CAGCAATACC TCCAAGCAGG TCAAATTCAG CCCCAGAACA GCCCAGCTCA 1020

CTGCACAGTT CCCAGGGACT TGGGATAGGT CCCGTGGAGG AGTCCTGGTT TGCTCCCTCC 1080

CTAGAGAACC AGCAGGAGGA GAATCAGCTC AGCTTGCAGA GTAAACTCCA GGAGGAAGCC 1140

AACTACCATC TTCATGGCAG CCGCATGGAC AGGCAGACAA AACCACTCAG ACAGAATGTG 1200

ATTTATAATA GAGAGGAGGA AAGGAGACGA AGGGTCTCCC ATGACCCTTT TGCACAGCCA 1260

AAACCTTATG AGAATGTTCA GAATCCAGGA GTAGGCCTTC CTTACTCTAG TGCAACCAGT 1320

CCTGGTAATG CACTACACCA ACCAACAGGG CCAACCAGCC AACCCCAAGT ACTGTACTGG 1380

AACAATGGAT TGAACAATCC ATTCTCTTTT GGAACAAGAC CACAGGATCT GGGAGCAGCA 1440

AGTTCAAGAG CTTGGTATGG GCCAAATCCA AACCATATGC CAAGTGTGCA TAAAACTCCA 1500

GTGCCTGAGA CCAACCTACT GGGAAACACA GCCACCCTTT CATTCGGCTC CTTCCCATCA 1560

AGAGATGAGT CTGTGAAATG TTCCATACGC AACAGTGCTG GCATTCAGAT TGGAGACCAT 1620

AATTACATGG AGATTAGTGG AATGAGTTCA GTGCCACTGG ACATGAACTT TAAAGAAGAG 1680

CCAGCTGCTA AGTACCACGA TATCTTTGAA AATATCACTA GTCTGACTGA CAAACATCTG 1740

GACCCAGTCA GGGAAAATCT GGGAAAGCAA TGGAAAAACT GTGCCCGTAA GCTGGGCTTC 1800

ACTGAACCTC AGATTGATGA AATTGACCAT GACTATGAGA GAGATGGACT AAAAGAAAAG 1860

GTTTACCAGA TGCTCCAAAA GTGGCAGATG AGGGAAGGCC AGCCTTGCCT TTATTGCTCA 1920

AGAAACTCAA ATGGCCAGTG A 1941

Domain Profile

S: 2     eelelvgsGgfgkvfkarhrkwrvevavkslvlktdaldserkelleeakkmeklrfsyv  61

          e e+++sGgfgkv+ + hr +++ +++k  v++++++++++++llee+k+m++lr+s+v

Q: 14    LEKEYLDSGGFGKVSLCLHRCHGLVILKK--VYTGPKRTEYNESLLEEGKMMHRLRHSRV  71

         57899************************..*****************************

S: 62    lkllGvikeeeklglvmeymenGsLeklLkseielpwplkfRilkevvlgmnyLhslkPp  121

         +kllGvi ee++++lvmeyme+G+L+++Lk+e+++p++lk Ri+ e+++gm+yLh ++

Q: 72    VKLLGVIIEEGNYSLVMEYMEKGNLMHVLKAEVSIPLSLKGRIIMEIIEGMCYLHGQG--  129

         **********************************************************..

S: 122   llhkDLkpeniLlDnelhvkiaDfGlskf.m......eessqskevsssa..egGtlaYl  172

         ++hkDLkpeniL+D ++h+kiaD+G+++f m      ee+++++++++ +  +gGtl Y+

Q: 130   IIHKDLKPENILVDDDFHIKIADLGVASFkMwskltkEEHNEQRKLNRVSkkNGGTLCYM  189

         *****************************889999998888888888766669*******

S: 173   aPelleevnkkaseksDvYsfaiviWavlakkepyeeeknslqiiivvkkgnRPeleevs  232

         aPe+l+++n+k+seksDvYsf+iv+Wa++a+kepye++++++q+ii++k+gnRP++e++

Q: 190   APEHLNDINAKPSEKSDVYSFGIVLWAIFANKEPYENAICEEQLIICIKSGNRPNVEDIL  249

         ************************************************************

S: 233   eelPrevpqlieLmkrcWeadpeeRPsFleieekt  267

         e++P+e   +i++mk+cWea+p+ RP+F ++eek+

Q: 250   EYCPEE---IISIMKQCWEAKPDIRPTFIGLEEKF  281

         ****88...*********************99986

Domain Sequence
(FASTA)

LEKEYLDSGG FGKVSLCLHR CHGLVILKKV YTGPKRTEYN ESLLEEGKMM HRLRHSRVVK 60

LLGVIIEEGN YSLVMEYMEK GNLMHVLKAE VSIPLSLKGR IIMEIIEGMC YLHGQGIIHK 120

DLKPENILVD DDFHIKIADL GVASFKMWSK LTKEEHNEQR KLNRVSKKNG GTLCYMAPEH 180

LNDINAKPSE KSDVYSFGIV LWAIFANKEP YENAICEEQL IICIKSGNRP NVEDILEYCP 240

EEIISIMKQC WEAKPDIRPT FIGLEEKF 268

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Microcebus murinus"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>