EKS-MUP-00097

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00097

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Atypical/PIKK	401.1	3.8E-120	3701	4050	350

Status

Unreviewed

Ensembl Protein

ENSMPUP00000001012

UniProt Accession

G9KIL8;

Protein Name

Protein Synonyms/Alias

Protein kinase, DNA-activated, catalytic polypeptide;

Gene Name

Prkdc

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000001020	ENSMPUP00000001012	ENSMPUT00000001033

Organism

Mustela putorius furo

Functional Description

Protein Length

4110

Protein Sequence
(FASTA)

ATASYQLIRG LGQECVLSSG PAVLALQTSL IFSKDFGLLV FVQKSLSIDE FRDCREEVLK 60

FLCIFLEKIG QKITPYSLEI KNTCTIVYTK DKAAKCKIPA LDLLIKLLRI LRSSRLMDEF 120

RIGELFSKFY GELASKTKVQ DTVLEKIYEL LGVLGEVHPS EMINNSEKLF RAFLGELKIQ 180

MTSAIREPKL PVLAGCLKGL SSLMCNFTKS MEEDPQTSRE IFYFALKAIR PQIDLKRYAV 240

PLAGLCLFTL HASQFSTCLL DNYVSLFEVL SKWCSHTNVE LKKAAHSALE SFLKQISFMV 300

AKDAEMHKSK LQYFMEQFYG IIRNMDSNSK DLSIAIRGYG LFAGPCKVVN AKDVDFMYVE 360

LIQRCKQLFL TQIDTVDDHV YHMPSFLQSI ASVLLYLDTV PEVYTPVLEH LMVVQIDSFP 420

QYSPKMQSVC CKAIVKVFLA LGGKGPVLWN CISTVVHQGL IRICSKPVIL QKGVESESED 480

CRASGEVRTG KWKMPTYKDY LDLFRSLLSC DQMMDSLLAD EAFFFVNSSL QNLNRLLYDE 540

FVKSVLKIIE KLDLTLEKQN AGGHEDENEA TGVWVIPTSD PAANFHPAKP KDFSAFINLV 600

EFCREILPEK HVEFFEPWIH SFAYELILQS TRLPLISGFY KLLSVAMRNA KKIKYFKGVG 660

LKSQTQSPED PEKYSCFALL AKFGKEVSIK MKQYKDELLA SCLTFILSLP HDIIELDIRA 720

YVPALQMAFK LGLSYTPLAE VALNALEEWS LYICKHVIQP HYTDILPSLD GYLKTSALSD 780

ETKNNWEVSA LSRAAQKGFN KVIIKHLKKT KNISSIHNPL FCRRVVLEVR TSVGSRVQGQ 840

KNQHFRTVAS SDEMMKKCVT WDREKRLSFA VPFIEMKPVI YLDVFLPRVT ELALSASNRQ 900

TKVAACELLH SMVMFMLGKA TQMPEGGQGF PPMYQLYKRT FPVLLRLACD VDQVTRQLYE 960

PLVMQLIHWF TSNKKFESQD TVALLETILD GIVDPVDSTL RDFCGRCIRE FLKWSIKQTT 1020

PQQQEKSPVN TKSLFKRLYS FALHPNAFKR LGASLAFNNI YRDFREEESL VEQFVFEALV 1080

TYLESLALAH ADEKSLGTLQ QCCDAIDHLR RIIEKKHVSL NKVKKRRRPR GFPPAASLCL 1140

LDVVQWLLAH CGRPQTECRH KSIELFYKFV PLLPGNTSPS LWLKDILKNK DTSFLINIFE 1200

GGGGDCDRLS GILAQPTLFH LQGPFSLRAV LQWMDMLLAA LECYNTFIEE KTLEASEVLG 1260

TETQSSLWKA MAFFLENIAM HDITAAEKCF GTGTTGHRPS PQEEERYNYS KCTIVVRIME 1320

FTTVLLSTSP EGWKLLEKDL CNNKNFMKLL VKTLCEPSSI GFNIGDVLVM NHLPDVCVKL 1380

IKALKKSPYK DTLEMHLKEK ITARSIEELC AVDLYGPDAY VDRAKLVSVV SACKQLHRAG 1440

FLHVVLPSQS ADQHHSVGTK LLSLVYKSIA PGDEREYFPS LDPSCKRLAN GLLELAFAFG 1500

GLCEHLVNLL LDTAMLSMPA SGVSQRNMVS FSHGEYFYSL FSEAINTELL KNLDFVVLEL 1560

MKSSVDNPKM VSTVLNGMLD QSFRDRASQK YQGQKLASTI LHNWKKWDSW WAKDSTPESK 1620

TAVLTLLAKI LQIDSSVSFN TNHSAFPEVF TTYSSLLADS KLGLHLKGQA VILLPFFTSL 1680

TGDSLEDLKH VLENLIVSNF PMKSEEFPPG TLRYNNYVDC MKKFLDALEL SQSPVLLQLM 1740

TEILCREQQH VMEELFQSTF KEIARKSSCV TQLALLERVY RMFKRDDLLS NVTRQAFVDR 1800

SLLTLLWHCS LNALREFFSK IVVDAIDVLR SRFTKLNESI FDTQITKKMG YYKMLEVMYS 1860

RLSKDDVHSK ESKINQVFYG SCVTEGNELT KTLIKLCYDA FTENMAGENQ LLERRRLYHC 1920

AAYNCAISVI CCVFTELKFY QGFLFSEKPE KNLLILENLI DLKRCYTFPI EVEVPMERKK 1980

KYIDIRKEAR EATNGDSGGP HYLSSLSYLA DSSLSEEMSQ FDFSTGVQSY SYSSQDPKST 2040

PGHFLRRERK DPLVQDAVLE LEMDELNQHE CMATMTTLIK HMHRNQILLK EEGSVPRNLP 2100

PWMKFLHDKL GNPSISLNIR LFLAKLVINT EEVFRPYAKY WLSPLLQLVV SENNGGRGIH 2160

YMVVEIVVTV LSWTGLATPV GVPKDEVLAN RLLHFLMEHV FHQKRAVFRH NLEIIKTLVE 2220

CWKDCLSVPY RLIFEKFSNK DPNSKDNSVG IQLLGIVIAN NLPPYDPKCG IESIKYFQAL 2280

VNNMSFVKYK EVYAAAAEVL GLILQYITKK ENVLKELVYE LIIKQLKQHQ NTMEDKFIVC 2340

LNKAVKNFPP LADRFMNTVF FLLPKFHGVM KTLCLEVVLC RAEEITDLYL QLKSKDFIQV 2400

MKHRDDERQK VCLDIIYTMM AKLKPVELRE LLNPVVEFIS HPSPVCREQM YNILMWVHDN 2460

YRDPESQADD ESREVFKLAK DVLIQGLIDE NAGLQLIIRN FWSHETRLPS NILDRLLALN 2520

SLYSPKIEMH FLSLATDFLL EMTSMSPDYP NPVFEHPLSE CEFQEYTIDS DWRFRSTIFT 2580

PMFIETQASQ SALQARTQEG SLPFQGVMAR QIRATQQQYD FTPTQTADGR SSFNWLTGSS 2640

IDPLMDYTVS SSLDSSSSSL LFAHKRSEKF QRAPLKSVGP DFGKKRLGLP GDEVDNKTKG 2700

IDNRTEILRL CRRFIKDQEK LSLIYARKGI AEQKREKEIK SELKMKHDAQ VILYRSYRQG 2760

DLPDIQIKYS SLITPLQAVA QRDPIIAKEL FGSLFSGIIK EMDKYKTKSE KNNITQKLLQ 2820

DFNHFLNSTF SFFPPFVSCI QEISCQHTDL LSLDPASVSA GCLASLQQSV GVRLLEEALL 2880

HPMPQEPPAK RFRGRTHLSP DVVRWMELAK LYRSIGEYDV LRSIFSSEIG TKQVTQSAIL 2940

AEARSDYSEA VKQYNEEALN KQEWVDGEPT EPEKDFWELA SLDCYNQLAE WKSLAYCSIV 3000

SIDNESPPDL NKMWSEPFYQ ETYLPYMIRS KLKLLLHGEA DQSLLTFIDE AVNKELQKAL 3060

IELHYSQELS LLYILQDDVD RAKYYIENCI QNFMQNYSSI DVLLHRSRLT KLQSVQTIIE 3120

IQEFISFISK QGNLSSQAPL KRLLNTWINR YPDTKMDPMN IWDDIITNRC FFLSKIEEKL 3180

TLPPGDHSMS MDDDKDSSDR MEVQEQGEEV CSLIKNCMFS MKMKMIESAR KQHNFSLAMK 3240

LLKELHRESK ARDDWQMQWV QSYCRLSHSR SQGQTCPEQI LTALKTVSLL GESTSSYISK 3300

NVLAFHDQNI LLGTTYRIIA EALIREPNCL AEIEESKARR ILDLSGSSTE NAGKVITGLH 3360

QRAFHHLSEA VRIAEEESQP SLMGQGPVAS LTDAYMTLVD FCDQQLRKEE ESASVTESLE 3420

LQTYPAVVVD KMLKALKLHS SEARLKFPRL LQIIELYPEE TLSLMTKEIS SIPCWQFIGW 3480

ISHMVALLDK EEAVAVQQTV EEIANNYPQA IAYPFIISSE SYSFKDTSTG HKNKEFVARI 3540

KIKLDQGGVI QDFISALEQL SNPEMLFKDW VDDMKVELAK TPVNKKNIEK MYERMYAALG 3600

NPRAPGLGAF RKRFIQDFGK EFDKHFGKGG SKLPGMKLRD FTDITDSLFY KMGRDSKPPG 3660

NLKECSPWMS DFKIEFLRSE LEIPGQYDGK GKPMPEYHAR ISGFDERVKV MASIRKPKRI 3720

IIRGHDEKEY PFLVKGGEDL RQDQRIEQLF EVMNVLLSQD AACSQRNMQL KTYHVIPMTS 3780

RLGLIEWIEN TFTLKDFLLS NMSREEKAAY ISDPKAPPCE YRDWLAKMSG KYNAGAYMAM 3840

FKAASRSETV TSFRRRESKV PADLLKRAFL KMSTGPEAFL ALRSHFASSH ALMCISHWIL 3900

GIGDRHLNNF MISMETGGMI GIDFGHAFGS ATQFLPVPEL MPFRLTRQFI NLMLPMKEGG 3960

VMSSVMVHAL RAFRSHSDLL INTMDVFVKE PSFDWKNFEQ KMLKKGGSWI QEINVTEKNW 4020

YPRQKIHYAK RKLAGANPAV ITCDELFLGH EKALAFGDYV AVARGSKDHN IRAQHPESGL 4080

SEEAQVKCLI DQATDPNILG RTWQGWEPWM 4110

Nucleotide Sequence
(FASTA)

GCGACGGCCA GTTATCAGCT GATCCGGGGC CTGGGACAGG AGTGCGTGCT GAGCTCCGGC 60

CCCGCGGTGC TGGCATTACA GACTTCCTTA ATTTTTTCCA AAGATTTTGG TTTGCTTGTG 120

TTTGTTCAGA AGTCACTTAG CATTGATGAA TTTCGTGATT GTAGAGAAGA AGTCTTAAAA 180

TTTTTATGTA TTTTCTTAGA AAAAATTGGC CAGAAGATCA CACCTTATTC TCTAGAAATT 240

AAGAATACTT GTACCATTGT TTACACAAAG GATAAAGCTG CTAAATGTAA AATCCCAGCC 300

CTAGATCTTC TTATTAAGTT ACTTCGGATT TTAAGAAGTT CTAGACTCAT GGATGAATTT 360

AGAATTGGAG AGTTATTTAG CAAATTCTAT GGAGAACTCG CATCGAAAAC AAAAGTACAG 420

GATACAGTTT TGGAAAAAAT ATATGAGCTT CTGGGAGTAT TAGGTGAAGT TCATCCTAGT 480

GAAATGATAA ATAATTCAGA AAAACTGTTC CGGGCTTTTC TGGGTGAACT TAAGATCCAG 540

ATGACATCAG CAATAAGAGA GCCCAAACTG CCTGTTCTGG CAGGGTGTCT GAAGGGCTTA 600

TCTTCACTCA TGTGTAACTT CACCAAATCC ATGGAAGAAG ATCCCCAGAC TTCAAGGGAG 660

ATTTTTTATT TTGCATTAAA GGCAATTCGT CCCCAGATTG ATCTGAAGAG ATATGCGGTA 720

CCCTTAGCTG GCTTATGCTT ATTTACCCTG CATGCATCTC AGTTTAGCAC CTGCCTTCTG 780

GACAACTACG TTTCTTTATT TGAAGTATTG TCAAAATGGT GTAGCCATAC AAATGTAGAA 840

TTGAAAAAAG CTGCACATTC AGCTCTGGAA TCTTTTCTGA AACAGATTTC TTTTATGGTG 900

GCAAAAGATG CGGAAATGCA TAAGAGTAAG CTACAGTACT TTATGGAGCA ATTCTATGGA 960

ATCATCAGGA ACATGGATTC AAACAGCAAA GATTTATCCA TTGCAATTCG TGGATATGGA 1020

CTTTTTGCAG GACCTTGCAA GGTTGTAAAT GCAAAAGATG TTGACTTCAT GTACGTAGAG 1080

CTCATTCAGC GCTGCAAGCA GCTGTTCCTC ACCCAGATAG ACACTGTTGA TGACCACGTT 1140

TACCACATGC CAAGTTTCCT CCAGTCTATT GCAAGTGTCT TGCTTTACCT TGATACAGTT 1200

CCTGAGGTGT ATACTCCAGT TCTGGAACAT CTCATGGTGG TACAGATAGA CAGTTTCCCA 1260

CAGTATAGTC CAAAAATGCA GTCAGTGTGT TGTAAAGCCA TAGTGAAAGT CTTCCTAGCC 1320

TTAGGGGGAA AAGGACCAGT TCTTTGGAAT TGCATCAGTA CCGTGGTGCA TCAGGGTTTA 1380

ATCAGAATAT GTTCTAAGCC AGTGATCCTT CAAAAGGGTG TTGAGTCTGA ATCTGAAGAC 1440

TGTCGTGCAT CAGGGGAAGT TAGAACTGGC AAGTGGAAAA TGCCCACATA TAAAGACTAT 1500

TTGGATCTTT TTAGAAGTCT CCTGAGTTGT GATCAGATGA TGGATTCTCT TTTAGCGGAT 1560

GAAGCATTTT TCTTTGTGAA TTCCTCCCTT CAAAATCTGA ATCGTTTGCT ATACGATGAA 1620

TTTGTCAAAT CAGTTTTGAA GATTATTGAG AAATTGGATC TTACACTAGA GAAACAGAAT 1680

GCTGGGGGAC ACGAGGATGA AAATGAAGCT ACTGGTGTTT GGGTGATCCC GACCTCAGAT 1740

CCAGCGGCTA ACTTCCATCC TGCTAAACCC AAAGATTTTT CAGCTTTCAT TAACCTGGTG 1800

GAATTTTGCA GAGAGATTCT TCCTGAGAAA CATGTAGAAT TTTTTGAGCC ATGGATACAT 1860

TCATTTGCAT ATGAATTAAT TTTGCAGTCT ACACGGTTGC CTCTCATCAG TGGTTTTTAC 1920

AAATTGCTCT CTGTTGCTAT GAGAAATGCC AAGAAAATAA AATATTTTAA GGGAGTTGGT 1980

CTGAAGAGTC AGACACAGTC TCCTGAGGAT CCAGAAAAAT ATTCTTGCTT TGCTTTACTT 2040

GCAAAATTTG GTAAAGAGGT ATCGATTAAA ATGAAGCAAT ACAAAGATGA ACTTTTGGCC 2100

TCCTGTTTGA CCTTTATTCT GTCCCTGCCA CATGACATCA TTGAACTTGA TATTAGAGCC 2160

TACGTTCCTG CATTACAGAT GGCTTTTAAA CTGGGCCTGA GCTATACCCC ATTGGCAGAA 2220

GTAGCCCTGA ATGCCCTAGA AGAATGGTCA CTTTACATCT GCAAACATGT AATTCAGCCC 2280

CATTATACAG ACATTTTACC CAGCCTTGAT GGATATCTGA AAACTTCAGC CTTATCAGAT 2340

GAGACCAAGA ACAACTGGGA AGTATCAGCA CTTTCTCGGG CTGCCCAGAA AGGATTTAAT 2400

AAAGTTATAA TAAAGCATCT GAAAAAGACA AAGAACATTT CATCAATACA CAATCCCTTA 2460

TTCTGTAGGA GAGTGGTTCT TGAAGTGAGG ACCTCAGTGG GTTCCAGGGT ACAAGGCCAA 2520

AAGAATCAAC ATTTTAGAAC AGTTGCATCC TCAGATGAAA TGATGAAGAA ATGTGTGACA 2580

TGGGACAGAG AAAAAAGACT CAGTTTTGCA GTACCATTTA TAGAAATGAA GCCTGTCATT 2640

TATCTGGATG TGTTCTTGCC TCGGGTCACA GAACTAGCTC TTTCAGCTAG TAACAGACAA 2700

ACTAAAGTTG CGGCTTGTGA GCTTCTACAC AGCATGGTTA TGTTTATGTT GGGAAAAGCC 2760

ACTCAGATGC CTGAAGGTGG TCAGGGTTTC CCACCCATGT ACCAGCTCTA CAAGCGAACT 2820

TTTCCTGTGC TACTTCGACT TGCATGTGAT GTAGATCAGG TGACAAGGCA ACTATACGAG 2880

CCCCTAGTTA TGCAGCTGAT TCACTGGTTC ACAAGCAATA AGAAATTTGA AAGTCAGGAT 2940

ACTGTCGCCT TACTAGAAAC GATATTGGAT GGAATTGTAG ACCCTGTTGA CAGTACTTTA 3000

AGAGATTTTT GTGGTCGGTG TATTCGCGAA TTCCTCAAGT GGTCCATTAA GCAGACAACA 3060

CCACAGCAGC AGGAAAAAAG TCCAGTAAAT ACCAAATCGC TTTTCAAACG ACTGTACAGC 3120

TTTGCACTTC ACCCCAATGC TTTCAAGAGG CTAGGGGCAT CACTTGCCTT TAATAATATC 3180

TATAGAGATT TCAGGGAAGA AGAGTCTCTG GTAGAACAGT TTGTGTTTGA AGCTTTGGTT 3240

ACATATCTGG AAAGTCTGGC CTTAGCACAT GCAGATGAGA AATCTTTAGG TACGCTTCAA 3300

CAATGTTGTG ATGCCATTGA TCACCTAAGG CGTATCATTG AAAAGAAGCA TGTATCTTTA 3360

AACAAAGTAA AAAAGCGACG TAGGCCACGA GGATTTCCAC CTGCAGCATC ATTGTGTTTA 3420

CTGGATGTGG TCCAATGGCT GTTAGCCCAC TGTGGGAGGC CCCAAACAGA ATGTCGACAT 3480

AAATCTATAG AACTCTTTTA TAAATTTGTT CCTTTATTGC CAGGCAACAC ATCCCCTTCT 3540

TTATGGCTGA AGGATATTCT CAAGAACAAA GATACTTCCT TTCTCATAAA CATATTTGAG 3600

GGGGGAGGAG GAGATTGTGA TCGGCTGTCA GGCATTCTTG CTCAGCCTAC TCTCTTCCAT 3660

CTGCAAGGGC CGTTCAGCCT GAGAGCTGTG TTGCAGTGGA TGGACATGCT TCTGGCGGCT 3720

TTGGAATGCT ACAACACATT CATTGAAGAG AAAACCCTTG AGGCATCTGA GGTCCTAGGT 3780

ACTGAAACAC AGTCTTCACT TTGGAAAGCA ATGGCTTTCT TTTTAGAAAA CATTGCTATG 3840

CATGATATTA CGGCAGCAGA AAAGTGCTTT GGCACTGGGA CAACAGGTCA CAGACCTAGC 3900

CCACAAGAGG AGGAAAGATA TAATTATAGC AAATGCACAA TTGTGGTACG GATTATGGAA 3960

TTTACCACAG TGCTGCTCAG CACCTCCCCA GAAGGCTGGA AGCTCCTTGA GAAGGATTTA 4020

TGTAATAACA AAAACTTTAT GAAACTATTG GTGAAAACCC TATGTGAGCC CTCGAGCATA 4080

GGTTTCAATA TTGGTGATGT CCTAGTTATG AATCATCTTC CCGATGTTTG TGTGAAGCTA 4140

ATAAAAGCAC TAAAGAAGTC CCCATACAAA GACACCCTGG AGATGCACCT TAAGGAAAAA 4200

ATAACAGCAC GGAGCATTGA GGAGCTCTGT GCTGTTGACC TATATGGCCC TGATGCTTAT 4260

GTGGACAGGG CCAAGCTGGT GTCTGTTGTG TCAGCTTGTA AACAACTTCA CAGAGCTGGT 4320

TTTTTGCATG TTGTATTACC ATCTCAGTCC GCAGATCAGC ATCATTCTGT TGGCACAAAA 4380

CTTCTTTCCC TGGTTTATAA AAGCATTGCA CCTGGAGATG AGCGAGAGTA TTTTCCTTCA 4440

CTAGACCCCA GTTGTAAGCG ATTAGCCAAT GGACTTCTGG AGTTGGCCTT TGCTTTTGGA 4500

GGACTGTGTG AACACCTTGT GAATCTTCTC CTGGACACAG CAATGTTATC TATGCCAGCC 4560

TCAGGAGTGT CCCAGAGAAA CATGGTCAGC TTTTCTCATG GAGAGTATTT TTATAGCTTG 4620

TTCTCAGAGG CAATCAACAC TGAATTATTG AAAAATCTAG ATTTTGTTGT ATTGGAGCTC 4680

ATGAAATCAT CTGTGGATAA TCCCAAAATG GTGAGCACCG TTTTGAATGG TATGTTAGAT 4740

CAGAGCTTTA GGGATCGAGC CAGCCAGAAA TACCAAGGAC AGAAACTTGC AAGTACAATT 4800

TTGCACAACT GGAAGAAGTG GGACTCCTGG TGGGCCAAAG ATTCTACTCC TGAAAGTAAA 4860

ACAGCAGTGC TGACCTTACT GGCCAAAATT TTGCAGATTG ATTCATCTGT ATCCTTTAAT 4920

ACAAATCACA GTGCATTCCC TGAAGTCTTT ACAACATATT CTAGTCTACT TGCTGATTCA 4980

AAGTTGGGTT TACATTTAAA GGGTCAGGCT GTAATTCTTC TTCCATTCTT CACCAGTCTT 5040

ACTGGAGACA GTCTTGAGGA CCTTAAGCAT GTTCTTGAAA ATCTTATTGT TTCTAATTTC 5100

CCTATGAAGT CTGAAGAATT TCCCCCGGGA ACTCTGCGGT ACAATAATTA TGTAGACTGC 5160

ATGAAAAAGT TTCTAGATGC ATTGGAATTA TCTCAAAGTC CTGTATTGTT GCAGTTGATG 5220

ACAGAAATTC TTTGTCGGGA ACAGCAACAT GTTATGGAAG AATTATTTCA ATCTACTTTC 5280

AAAGAGATTG CCAGAAAGAG TTCATGTGTC ACACAATTAG CCCTTTTGGA AAGGGTATAC 5340

AGAATGTTCA AGAGGGATGA CCTGCTTTCA AATGTTACTC GCCAAGCATT TGTAGATCGC 5400

TCTCTCCTCA CCCTGTTGTG GCATTGTAGC CTGAATGCTT TGAGAGAATT CTTTAGCAAA 5460

ATTGTGGTGG ATGCCATTGA TGTGTTGAGG TCGAGATTTA CAAAGCTAAA TGAATCTATC 5520

TTTGATACTC AAATCACTAA GAAGATGGGC TATTATAAAA TGCTAGAAGT CATGTATTCT 5580

CGTCTTTCAA AAGATGATGT TCACTCAAAA GAATCTAAAA TTAACCAAGT TTTCTACGGC 5640

TCATGTGTTA CAGAAGGAAA TGAACTTACA AAGACACTTA TTAAATTGTG CTATGATGCA 5700

TTTACAGAGA ACATGGCGGG TGAGAATCAG TTGCTGGAGA GGAGAAGACT TTACCACTGT 5760

GCTGCGTACA ACTGTGCCAT TTCTGTTATC TGCTGTGTCT TCACTGAATT AAAATTTTAC 5820

CAAGGTTTTC TCTTTAGTGA AAAACCTGAA AAGAACTTGC TTATTTTGGA AAATCTGATT 5880

GACCTGAAGC GCTGCTATAC ATTTCCTATA GAAGTTGAGG TTCCTATGGA AAGAAAGAAA 5940

AAATACATTG ATATTAGGAA AGAAGCCAGG GAAGCCACAA ATGGGGATTC AGGAGGTCCT 6000

CATTATCTAT CTTCCTTGTC ATATTTGGCA GACAGCAGCC TGAGTGAGGA AATGAGTCAA 6060

TTTGATTTCT CAACTGGAGT TCAAAGCTAT TCATACAGTT CCCAAGACCC TAAATCTACC 6120

CCTGGTCATT TTCTGAGACG GGAGCGTAAA GACCCCCTGG TCCAAGATGC TGTCCTAGAG 6180

TTAGAGATGG ATGAACTCAA TCAGCATGAA TGTATGGCAA CCATGACAAC CCTGATTAAG 6240

CACATGCACA GAAATCAGAT ACTACTTAAA GAAGAGGGGT CAGTGCCAAG AAATCTTCCT 6300

CCATGGATGA AATTTCTTCA CGACAAACTA GGAAATCCAT CGATATCATT AAATATCCGT 6360

CTCTTCTTAG CCAAGCTTGT TATTAATACG GAAGAAGTCT TTCGCCCTTA TGCAAAGTAC 6420

TGGCTAAGTC CCTTGCTGCA GCTGGTGGTT TCTGAAAATA ATGGAGGCAG AGGAATTCAC 6480

TATATGGTGG TTGAGATTGT GGTTACTGTT CTTTCGTGGA CAGGATTAGC TACTCCTGTG 6540

GGTGTCCCTA AAGATGAAGT GTTGGCAAAT CGATTGCTTC ATTTCCTAAT GGAACATGTT 6600

TTTCATCAAA AAAGAGCTGT GTTTAGACAT AACCTTGAAA TTATAAAAAC CCTTGTTGAA 6660

TGCTGGAAGG ATTGTTTATC TGTCCCTTAC AGGTTAATAT TTGAGAAGTT TTCCAATAAA 6720

GATCCCAATT CTAAAGACAA TTCAGTAGGA ATTCAATTAT TAGGCATTGT AATAGCCAAT 6780

AATTTGCCTC CATATGACCC AAAATGTGGC ATAGAGAGCA TAAAATACTT TCAAGCTTTG 6840

GTCAATAATA TGTCCTTTGT AAAATATAAA GAGGTGTATG CGGCAGCAGC AGAAGTTCTA 6900

GGACTTATTC TTCAATATAT TACCAAGAAA GAAAATGTAT TGAAGGAGTT GGTGTATGAA 6960

CTGATCATAA AGCAGTTGAA GCAACATCAG AATACGATGG AGGACAAATT TATTGTGTGC 7020

TTGAACAAAG CCGTGAAGAA CTTTCCTCCT CTTGCCGATA GGTTTATGAA CACCGTGTTC 7080

TTCCTGCTGC CAAAGTTTCA CGGCGTAATG AAGACCCTCT GTCTGGAGGT GGTGTTGTGT 7140

CGTGCGGAGG AAATAACAGA TCTCTATTTA CAGTTGAAGA GCAAGGATTT CATTCAAGTC 7200

ATGAAACACA GAGATGATGA AAGACAGAAA GTGTGTTTGG ACATAATTTA TACAATGATG 7260

GCAAAATTGA AACCTGTAGA ACTCCGAGAA CTTCTGAATC CTGTTGTAGA ATTCATTTCT 7320

CATCCTTCTC CAGTATGCAG GGAACAAATG TATAACATTC TAATGTGGGT TCATGACAAT 7380

TACCGAGATC CAGAAAGTCA AGCAGATGAT GAGTCTCGGG AAGTATTTAA GTTGGCAAAA 7440

GATGTATTGA TTCAAGGGCT GATCGATGAG AATGCTGGGC TTCAATTAAT TATTCGAAAT 7500

TTCTGGAGCC ATGAGACTAG ATTACCTTCA AATATCTTGG ACCGACTGTT GGCACTAAAT 7560

TCCTTATATT CTCCAAAGAT AGAAATGCAC TTTTTAAGTT TAGCAACAGA TTTTCTGCTT 7620

GAAATGACCA GCATGAGCCC AGATTATCCA AACCCTGTGT TTGAGCATCC TCTGTCAGAA 7680

TGCGAATTTC AGGAATATAC CATTGATTCT GACTGGCGTT TCCGAAGTAC TATTTTCACT 7740

CCAATGTTTA TTGAGACTCA GGCCTCCCAA AGTGCTCTGC AGGCCCGGAC CCAGGAGGGA 7800

TCCCTCCCAT TTCAAGGGGT GATGGCTAGG CAGATACGGG CCACCCAACA ACAGTATGAC 7860

TTCACACCTA CACAAACTGC AGATGGCAGA AGCTCCTTTA ATTGGCTGAC TGGGAGCAGT 7920

ATTGACCCAC TGATGGATTA TACAGTCTCC TCATCATTGG ATTCCTCATC TTCCTCCTTG 7980

CTGTTTGCCC ACAAGAGGAG TGAAAAGTTC CAGAGAGCAC CCTTGAAGTC AGTGGGACCT 8040

GATTTTGGGA AAAAAAGGCT GGGCCTTCCA GGAGATGAGG TGGATAACAA AACAAAAGGT 8100

ATAGACAATC GGACAGAAAT ATTAAGATTA TGCAGGCGAT TTATAAAGGA CCAAGAAAAG 8160

CTCAGTTTGA TTTATGCCAG AAAAGGTATT GCTGAACAAA AACGAGAGAA GGAGATAAAG 8220

AGTGAGTTAA AAATGAAGCA CGATGCCCAA GTCATTTTAT ACAGGAGTTA CCGTCAAGGA 8280

GACCTTCCTG ACATTCAGAT TAAATACAGT AGCCTGATCA CCCCCTTGCA AGCTGTGGCT 8340

CAGAGAGACC CAATAATTGC AAAAGAGCTC TTTGGCAGCT TGTTTTCTGG AATTATAAAA 8400

GAGATGGATA AATACAAGAC CAAGTCTGAG AAAAACAACA TTACTCAAAA GTTGCTACAG 8460

GACTTTAATC ATTTTCTTAA CAGCACTTTC TCTTTCTTTC CACCTTTTGT CTCTTGTATC 8520

CAGGAAATCA GTTGCCAACA CACAGACTTG CTGAGCCTCG ACCCAGCTTC TGTCAGTGCT 8580

GGCTGCCTGG CCAGTCTACA GCAGTCTGTG GGTGTCCGCC TTCTCGAGGA GGCCCTGCTC 8640

CACCCGATGC CTCAAGAACC ACCTGCCAAG AGGTTTCGGG GGAGGACTCA CCTCTCTCCT 8700

GATGTCGTCA GATGGATGGA ACTTGCTAAA CTATATAGGT CAATTGGAGA ATATGATGTC 8760

CTCCGCAGTA TTTTTAGCAG TGAGATAGGA ACAAAGCAAG TCACTCAGAG TGCTATATTA 8820

GCAGAAGCAA GAAGTGATTA TTCTGAAGCT GTTAAACAGT ATAATGAGGA GGCTCTCAAT 8880

AAACAAGAGT GGGTGGATGG TGAGCCTACG GAACCTGAGA AGGATTTTTG GGAGCTTGCA 8940

TCCCTCGACT GTTATAACCA GCTTGCTGAG TGGAAATCAT TGGCATACTG TTCTATAGTC 9000

AGCATTGATA ATGAAAGCCC TCCAGATCTA AATAAAATGT GGAGTGAACC ATTTTATCAG 9060

GAGACCTATC TACCTTACAT GATCCGCAGC AAGCTGAAGT TACTGCTTCA TGGGGAGGCT 9120

GACCAGTCCC TGCTGACGTT TATTGATGAA GCTGTGAACA AAGAGCTTCA GAAGGCTCTT 9180

ATAGAGCTGC ACTATAGTCA AGAATTGAGC CTTCTTTACA TCTTACAAGA TGATGTTGAC 9240

AGAGCCAAAT ATTATATTGA AAATTGCATT CAGAATTTTA TGCAGAATTA CTCAAGTATT 9300

GATGTCCTCT TACACAGAAG TAGACTCACC AAATTGCAAT CTGTACAAAC TATAATAGAA 9360

ATTCAGGAGT TCATCAGTTT TATAAGCAAA CAAGGTAATT TATCATCTCA AGCTCCCCTT 9420

AAGAGACTTC TAAATACCTG GATAAACAGA TACCCAGATA CTAAAATGGA CCCAATGAAC 9480

ATCTGGGATG ACATTATCAC AAATCGATGT TTCTTTCTCA GCAAAATAGA GGAGAAACTT 9540

ACTCTTCCTC CAGGTGATCA TAGTATGTCC ATGGATGATG ATAAAGATTC TAGTGATAGG 9600

ATGGAAGTGC AGGAGCAGGG AGAAGAAGTC TGTTCCCTGA TTAAGAATTG TATGTTCTCC 9660

ATGAAAATGA AGATGATAGA AAGTGCAAGA AAGCAGCACA ATTTCTCACT TGCCATGAAA 9720

CTACTGAAGG AGCTTCATAG AGAGTCAAAA GCAAGAGATG ACTGGCAGAT GCAGTGGGTG 9780

CAGAGCTACT GCCGGCTCAG CCATAGCCGG AGCCAGGGCC AGACCTGCCC TGAGCAGATT 9840

CTCACAGCGC TGAAAACAGT CTCCTTATTG GGTGAGAGCA CATCAAGTTA CATAAGCAAA 9900

AATGTTCTTG CTTTCCATGA TCAGAATATT CTTTTGGGTA CAACATACAG AATCATAGCT 9960

GAGGCTCTCA TCAGGGAGCC AAACTGCCTC GCTGAAATCG AGGAAAGCAA GGCTAGAAGA 10020

ATTTTGGATC TTTCTGGATC CAGTACAGAG AATGCAGGAA AGGTGATCAC AGGTCTGCAC 10080

CAAAGAGCAT TCCATCACCT TTCTGAGGCC GTGCGGATAG CTGAGGAGGA GTCCCAGCCT 10140

TCCCTCATGG GCCAGGGTCC TGTAGCCAGC CTGACAGATG CTTACATGAC GCTGGTGGAT 10200

TTCTGTGACC AGCAGCTCCG CAAGGAGGAG GAGAGTGCAT CAGTTACTGA GTCTCTAGAA 10260

CTACAGACGT ATCCAGCCGT TGTGGTAGAC AAAATGTTGA AAGCTTTAAA ATTGCATTCC 10320

AGTGAAGCCA GGCTGAAGTT TCCTAGACTA CTGCAGATTA TAGAACTATA TCCAGAGGAG 10380

ACCCTGAGCC TAATGACAAA AGAGATTTCT TCCATTCCTT GCTGGCAGTT CATTGGCTGG 10440

ATCAGCCATA TGGTGGCCTT ACTGGACAAA GAGGAAGCTG TTGCTGTCCA GCAAACTGTG 10500

GAAGAGATTG CTAATAACTA TCCACAGGCA ATTGCCTACC CCTTTATAAT AAGTAGTGAA 10560

AGCTATTCCT TCAAAGATAC TTCTACTGGC CATAAGAATA AGGAGTTTGT GGCAAGGATT 10620

AAAATTAAGT TGGATCAAGG AGGAGTGATT CAAGATTTTA TTAGTGCCCT AGAACAGCTC 10680

TCTAATCCTG AAATGCTCTT TAAGGATTGG GTTGATGATA TGAAAGTCGA ACTGGCAAAA 10740

ACCCCTGTTA ATAAAAAAAA CATTGAAAAG ATGTATGAAA GAATGTATGC AGCCTTGGGA 10800

AACCCAAGGG CTCCAGGCCT TGGGGCTTTC AGAAAGCGGT TTATTCAGGA TTTTGGGAAA 10860

GAATTTGATA AACACTTTGG GAAAGGAGGT TCTAAGTTAC CTGGAATGAA ACTCCGCGAC 10920

TTTACTGACA TTACTGACTC ACTGTTTTAT AAAATGGGCA GAGACTCAAA GCCACCTGGG 10980

AATCTGAAAG AATGCTCACC CTGGATGAGT GACTTCAAAA TAGAATTTTT GAGAAGTGAG 11040

CTGGAGATTC CTGGTCAATA TGATGGCAAA GGAAAGCCAA TGCCAGAATA CCATGCACGA 11100

ATCTCTGGGT TTGATGAGCG GGTAAAAGTC ATGGCCTCTA TCAGAAAGCC AAAGCGCATC 11160

ATCATCCGAG GCCACGATGA GAAAGAATAC CCTTTCCTTG TCAAGGGGGG TGAAGACCTA 11220

CGGCAGGACC AGCGGATTGA ACAACTCTTT GAAGTCATGA ATGTCCTCCT TTCTCAGGAT 11280

GCTGCCTGTA GCCAGAGAAA CATGCAGTTG AAGACCTACC ATGTCATACC CATGACCTCC 11340

AGATTAGGAC TAATTGAATG GATTGAAAAT ACTTTCACCT TGAAGGACTT TCTTTTGAGT 11400

AACATGTCAC GAGAGGAGAA AGCAGCTTAT ATAAGTGATC CCAAAGCACC ACCATGTGAA 11460

TATAGAGACT GGCTGGCAAA GATGTCTGGG AAATACAATG CTGGTGCTTA CATGGCAATG 11520

TTTAAGGCAG CTAGTCGTTC TGAAACAGTC ACATCTTTTA GAAGGAGAGA AAGTAAAGTG 11580

CCAGCTGATC TCTTAAAGCG GGCCTTTCTG AAGATGAGCA CAGGCCCTGA GGCCTTCCTG 11640

GCACTTCGCT CCCACTTTGC CAGTTCTCAT GCTCTTATGT GTATTAGCCA CTGGATTCTG 11700

GGCATTGGAG ACAGACATCT GAACAATTTC ATGATAAGCA TGGAGACAGG TGGAATGATC 11760

GGAATCGACT TTGGACATGC ATTTGGATCA GCTACTCAGT TTCTGCCAGT CCCTGAATTG 11820

ATGCCTTTTC GTCTGACACG CCAATTTATC AATCTGATGT TACCAATGAA AGAAGGAGGT 11880

GTTATGTCCA GTGTCATGGT GCATGCACTG AGAGCCTTCC GCTCACACTC TGACCTGCTT 11940

ATTAACACCA TGGACGTGTT CGTAAAGGAA CCTTCCTTCG ACTGGAAAAA CTTTGAACAG 12000

AAAATGCTAA AAAAAGGAGG ATCGTGGATT CAAGAAATAA ATGTAACTGA AAAAAATTGG 12060

TATCCCCGGC AAAAAATACA TTATGCTAAG AGAAAGTTAG CAGGTGCCAA CCCAGCAGTT 12120

ATTACCTGTG ATGAGCTGTT CCTGGGCCAT GAGAAGGCAC TTGCCTTTGG AGATTATGTG 12180

GCTGTAGCAC GAGGAAGCAA AGATCACAAC ATTCGTGCCC AACACCCAGA GAGTGGGCTG 12240

TCAGAAGAGG CTCAAGTCAA GTGCTTGATT GACCAGGCTA CAGACCCCAA CATCCTTGGT 12300

AGAACTTGGC AAGGATGGGA GCCCTGGATG TGA 12333

Domain Profile

S: 1     iagfderveilaskqkpkklllrGsdgkeypyLvkgkeDlrqdervlqlfslvNtlLakd  60

         i gfderv+++as +kpk++++rG+d+keyp+Lvkg eDlrqd+r++qlf+++N lL +d

Q: 3701  ISGFDERVKVMASIRKPKRIIIRGHDEKEYPFLVKGGEDLRQDQRIEQLFEVMNVLLSQD  3760

         789*********************************************************

S: 61    ketsrrkLkirtykVvplstrsgliewventvsLkellkkl..vekkavlldqpi..syr  116

         +++s+r+++++ty+V+p+++r+gliew+ent +Lk++l     +e+ka++ ++p+  +++

Q: 3761  AACSQRNMQLKTYHVIPMTSRLGLIEWIENTFTLKDFLLSNmsREEKAAYISDPKapPCE  3820

         ************************************9987657999********999***

S: 117   ykdlstvqarkpklkhlkls.........levfkevlenlvpkdllkklllekfpspeew  167

         y d+ ++++ k ++ +++ +         +++f+ ++++ vp+dllk+++l++++ pe++

Q: 3821  YRDWLAKMSGKYNAGAYMAMfkaasrsetVTSFRRRESK-VPADLLKRAFLKMSTGPEAF  3879

         ***************************************.********************

S: 168   felrkaytrslAvislvgyiLgLgdrhlenllidqetgevvhidfgvafekaktqlkvpe  227

         ++lr+++++s+A+++++++iLg+gdrhl+n++i +etg ++ idfg+af++a+++l+vpe

Q: 3880  LALRSHFASSHALMCISHWILGIGDRHLNNFMISMETGGMIGIDFGHAFGSATQFLPVPE  3939

         ************************************************************

S: 228   kvPFRLTrnivnalgvtgveGvfrasceavlrvlreskeklltiLevflydplvdwkk..  285

          +PFRLTr+++n++ ++++ Gv+++ ++++lr++r++ + l ++++vf+++p++dwk+

Q: 3940  LMPFRLTRQFINLMLPMKEGGVMSSVMVHALRAFRSHSDLLINTMDVFVKEPSFDWKNfe  3999

         ************************************************************

S: 286   ....kkktsketeeelaekakaealkikkllskvekaenavatrdllllee  332

             kk++s+++e++++ek++++++ki+++++k+++a++av+t+d+l l++

Q: 4000  qkmlKKGGSWIQEINVTEKNWYPRQKIHYAKRKLAGANPAVITCDELFLGH  4050

         **9999***************************************999886

Domain Sequence
(FASTA)

ISGFDERVKV MASIRKPKRI IIRGHDEKEY PFLVKGGEDL RQDQRIEQLF EVMNVLLSQD 60

AACSQRNMQL KTYHVIPMTS RLGLIEWIEN TFTLKDFLLS NMSREEKAAY ISDPKAPPCE 120

YRDWLAKMSG KYNAGAYMAM FKAASRSETV TSFRRRESKV PADLLKRAFL KMSTGPEAFL 180

ALRSHFASSH ALMCISHWIL GIGDRHLNNF MISMETGGMI GIDFGHAFGS ATQFLPVPEL 240

MPFRLTRQFI NLMLPMKEGG VMSSVMVHAL RAFRSHSDLL INTMDVFVKE PSFDWKNFEQ 300

KMLKKGGSWI QEINVTEKNW YPRQKIHYAK RKLAGANPAV ITCDELFLGH 350

Keyword

ATP-binding; Kinase; Nucleotide-binding; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005958	; C:DNA-dependent protein kinase-DNA ligase 4 complex
GO:0005667	; C:transcription factor complex
GO:0005524	; F:ATP binding
GO:0004677	; F:DNA-dependent protein kinase activity
GO:0006915	; P:apoptotic process
GO:0002326	; P:B cell lineage commitment
GO:0007420	; P:brain development
GO:0032869	; P:cellular response to insulin stimulus
GO:0006302	; P:double-strand break repair
GO:0035234	; P:germ cell programmed cell death
GO:0007507	; P:heart development
GO:0033152	; P:immunoglobulin V(D)J recombination
GO:0018105	; P:peptidyl-serine phosphorylation
GO:0043065	; P:positive regulation of apoptotic process
GO:0045944	; P:positive regulation of transcription from RNA polymerase II promoter
GO:0002328	; P:pro-B cell differentiation
GO:0031648	; P:protein destabilization
GO:0010332	; P:response to gamma radiation
GO:0001756	; P:somitogenesis
GO:0033077	; P:T cell differentiation in thymus
GO:0002360	; P:T cell lineage commitment
GO:0033153	; P:T cell receptor V(D)J recombination
GO:0000723	; P:telomere maintenance

KEGG

InterPros

IPR003152	; FATC.
IPR011009	; Kinase-like_dom.
IPR000403	; PI3/4_kinase_cat_dom.
IPR018936	; PI3/4_kinase_CS.
IPR003151	; PIK-rel_kinase_FAT.
IPR014009	; PIK_FAT.

Pfam

PF02259	; FAT; 1.
PF02260	; FATC; 1.
PF00454	; PI3_PI4_kinase; 1.

SMARTs

SM00146

; PI3Kc; 1.

Prosites

PS51189	; FAT; 1.
PS51190	; FATC; 1.
PS00915	; PI3_4_KINASE_1; 1.
PS00916	; PI3_4_KINASE_2; 1.
PS50290	; PI3_4_KINASE_3; 1.

Prints

Created Date

20-Feb-2013