EKS-MUP-00450

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00450

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
Other/VPS15	504.1	9.4E-152	26	310	285

Status

Unreviewed

Ensembl Protein

ENSMPUP00000001734

UniProt Accession

G9KGN4;

Protein Name

Protein Synonyms/Alias

Phosphoinositide-3-kinase, regulatory subunit 4;

Gene Name

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000001752	ENSMPUP00000001734	ENSMPUT00000001770

Organism

Mustela putorius furo

Functional Description

Protein Length

490

Protein Sequence
(FASTA)

MGNQLAGIAP SQILSVESYF SDIHDFEYDK SLGSTRFFKV ARAKHREGLV VVKVFAIQDP 60

TLPLTSYKQE LEELKIRLHS AQNCLPFQKA VEKASEKAAM LFRQYVRDNL YDRISTRPFL 120

NNIEKRWIAF QILTAVDQAH KSGVRHGDIK TENVMVTSWN WVLLTDFASF KPTYLPEDNP 180

ADFNYFFDTS RRRTCYIAPE RFVDGGLFAT ELEYMRDPST PLVDLNSNQR TRGELKRAMD 240

IFSAGCVIAE LFTEGVPLFD LSQLLAYRNG QFFPEQVLNK IEDCSIRELV TQMIHREPDK 300

RLGAEDYLKQ QRGNAFPEIF YTFLQPYMAQ FAKETFLSAD ERILVIRKDL GNIIHNLCGH 360

DLPEKAEGEP KENGLVILVS VITSCLQTLK YCDSKLAALE LILHLAPRLS VEILLDRITP 420

YLLHFSNDSV PRVRAEALRT LTKVLALVKE VPRNDVNIYP EYILPGIAHL AQDDATIVRL 480

AYAGKNLLSK 490

Nucleotide Sequence
(FASTA)

ATGGGAAATC AGCTTGCTGG CATTGCTCCT TCCCAGATCC TTTCTGTGGA GAGTTATTTC 60

TCAGACATCC ATGATTTTGA ATATGATAAG AGTCTGGGAA GTACTCGGTT TTTTAAAGTT 120

GCTCGAGCGA AGCACCGAGA AGGCCTTGTG GTTGTGAAGG TCTTTGCAAT TCAGGATCCC 180

ACATTGCCTT TAACCAGCTA TAAACAAGAG CTAGAGGAAC TGAAAATCAG GCTTCATTCT 240

GCACAGAACT GTCTACCTTT TCAGAAAGCA GTAGAAAAAG CATCTGAGAA AGCAGCCATG 300

CTCTTTAGGC AATATGTGCG AGACAACCTT TATGATCGCA TCAGTACCCG TCCATTCTTA 360

AATAACATTG AAAAGCGTTG GATTGCTTTC CAGATTCTGA CAGCTGTGGA CCAAGCACAC 420

AAATCTGGAG TCCGTCATGG GGACATCAAG ACTGAGAATG TAATGGTCAC CAGTTGGAAT 480

TGGGTCCTTC TAACTGATTT TGCTAGTTTT AAGCCCACTT ATCTTCCAGA GGACAACCCA 540

GCAGATTTCA ACTATTTCTT TGACACTTCA CGGAGGAGAA CTTGCTATAT TGCTCCTGAA 600

CGTTTTGTTG ATGGTGGATT GTTTGCCACT GAGTTAGAAT ACATGAGGGA TCCTTCAACT 660

CCACTTGTAG ACTTAAATAG TAATCAGAGA ACAAGAGGAG AGTTGAAGAG GGCAATGGAT 720

ATCTTTTCAG CAGGTTGTGT TATAGCTGAG CTTTTTACAG AAGGTGTACC ACTGTTTGAT 780

CTCTCTCAAC TTCTGGCTTA TAGAAATGGA CAGTTTTTCC CGGAACAAGT GCTAAATAAA 840

ATTGAAGATT GCAGTATCAG AGAATTGGTA ACTCAGATGA TTCACCGTGA GCCAGATAAA 900

CGTTTAGGGG CAGAAGATTA CCTAAAGCAG CAGCGTGGCA ATGCCTTTCC TGAAATATTT 960

TACACATTCC TTCAGCCCTA CATGGCCCAG TTTGCCAAGG AAACATTTCT TTCTGCAGAT 1020

GAGCGCATTC TGGTTATACG GAAGGATTTG GGCAACATTA TTCACAATCT CTGTGGACAT 1080

GATCTGCCAG AAAAAGCAGA AGGAGAGCCT AAGGAAAATG GGCTGGTTAT CTTGGTGTCT 1140

GTTATAACGT CCTGTTTGCA GACCCTTAAA TACTGTGATT CCAAACTTGC TGCTTTGGAA 1200

CTTATTCTCC ATTTGGCCCC AAGATTAAGT GTAGAAATTC TTTTGGATCG TATTACTCCA 1260

TATCTTTTAC ATTTCAGCAA TGACTCTGTT CCTAGAGTGA GGGCTGAAGC CTTGAGGACG 1320

TTGACCAAAG TTCTTGCTCT TGTCAAAGAG GTTCCTCGCA ATGATGTCAA TATCTATCCG 1380

GAATATATTC TGCCAGGCAT AGCCCACTTA GCCCAAGATG ATGCTACTAT TGTTAGACTA 1440

GCCTATGCTG GTAAGAACTT ATTGTCCAAG TAA 1473

Domain Profile

S: 1     veyvknlgstrflkvakakteeGeivvkvfvkqdptlslesfkqrleelklklakaqncl  60

         +ey+k+lgstrf+kva+ak++eG++vvkvf++qdptl+l+s+kq+leelk++l++aqncl

Q: 26    FEYDKSLGSTRFFKVARAKHREGLVVVKVFAIQDPTLPLTSYKQELEELKIRLHSAQNCL  85

         68**********************************************************

S: 61    pfqkvlek..ekaavllrqyvkdnlydrlstrPflneiekkwiafqllkaldqihksgvv  118

         pfqk++ek  ekaa+l+rqyv+dnlydr+strPfln+iek+wiafq+l+a+dq+hksgv+

Q: 86    PFQKAVEKasEKAAMLFRQYVRDNLYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVR  145

         ******9999**************************************************

S: 119   hGdiktenvlvtswnWvlltdfasfkPtylpednPadftyffdtsrrrtcyiaPerfvsa  178

         hGdiktenv+vtswnWvlltdfasfkPtylpednPadf+yffdtsrrrtcyiaPerfv++

Q: 146   HGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNPADFNYFFDTSRRRTCYIAPERFVDG  205

         ************************************************************

S: 179   lasdekl...rdgstelvdldsiqrlrgelkkamdifsaGcvilelftegrplfelsqll  235

         + ++++l   rd+st+lvdl+s+qr+rgelk+amdifsaGcvi+elfteg+plf+lsqll

Q: 206   GLFATELeymRDPSTPLVDLNSNQRTRGELKRAMDIFSAGCVIAELFTEGVPLFDLSQLL  265

         ******9999**************************************************

S: 236   ayrsgeflvekvlekiededlrnlvlqliqlepekrksaedllkk  280

         ayr+g+f++e+vl+kied ++r+lv+q+i++ep+kr+ aed+lk+

Q: 266   AYRNGQFFPEQVLNKIEDCSIRELVTQMIHREPDKRLGAEDYLKQ  310

         *******************************************97

Domain Sequence
(FASTA)

FEYDKSLGST RFFKVARAKH REGLVVVKVF AIQDPTLPLT SYKQELEELK IRLHSAQNCL 60

PFQKAVEKAS EKAAMLFRQY VRDNLYDRIS TRPFLNNIEK RWIAFQILTA VDQAHKSGVR 120

HGDIKTENVM VTSWNWVLLT DFASFKPTYL PEDNPADFNY FFDTSRRRTC YIAPERFVDG 180

GLFATELEYM RDPSTPLVDL NSNQRTRGEL KRAMDIFSAG CVIAELFTEG VPLFDLSQLL 240

AYRNGQFFPE QVLNKIEDCS IRELVTQMIH REPDKRLGAE DYLKQ 285

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona intestinalis"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Drosophila melanogaster"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sorex araneus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>