EKS-MUP-00212

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00212

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/CDKL	464.4	9.8E-140	13	297	285

Status

Unreviewed

Ensembl Protein

ENSMPUP00000002872

Gene Name

CDKL5

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000002901	ENSMPUP00000002872	ENSMPUT00000002931

Organism

Mustela putorius furo

Protein Length

933

Protein Sequence
(FASTA)

MKIPNIGNVM NKFEILGVVG EGAYGVVLKC RHKETHEIVA IKKFKDSEEN EEVKETTLRE 60

LKMLRTLKQE NIVELKEAFR RRGKLYLVFE YVEKNMLELL EEMPNGVPPE KVKSYIYQLI 120

KAIHWCHKND IVHRDIKPEN LLISHNDVLK LCDFGFARNL SEGNNANYTE YVATRWYRSP 180

ELLLGAPYGK SVDMWSVGCI LGELSDGQPL FPGESEIDQL FTIQKVLGPL PSEQMKLFYS 240

NPRFHGLRFP AVNHPQTLER RYLGILNSVL LDLMKNLLKL DPADRYLTEQ CLNHPTFQTQ 300

RLLDRSPSRS AKRKPYHVES STLSNRNQAS KSAALQSHHR SNSKDIQNLG VGLPRADEGL 360

PANESFLNGN LAGATLSPMH TKTYQASSQP GSTSKDLTNN NIPHLLSPKE AKSKTEFDFN 420

IDPKPSEGPG TKYLKSSSRS QQNRHSFMES SQSKAGTLQP TEKQSRHSYI DTIPQSSRSP 480

SYRTKAKSHG ALSDSKSVSN LSEARAQIAE SNTNRYFPSS CLDLNSPTSP TPTRHSDTRT 540

LLSPSGRNNR SEGTLDSRRT ATRHSKTMEE LKLPEHMDSS HSHSLSAPHE SFSYGLGYTS 600

PFSSQQRPHR HSMYVTRDKV RAKGLDGSLS VGQGMAARAN SLQLLSPQPG EQLPPEMTVA 660

RSSGKESSRE GTTSFHARQK SEGGAYHDPH SDDGTAPKEN RHLYNDPVPR RVGSFYRVPS 720

PRPDNSFHEN NVSTRVSSLP SESSSGTNHS KRQPAFDPWK SPENISHSEQ LKEKEKQGFF 780

RSMKKKKKKS QTVPNSDGPD LLTLQKAIHS ASTPSSRPKE WRPEKISDLQ TQSQPLKSLR 840

KLLHLSSASN HPASSDPRFQ PLTTQQAKNS FSEIRIHPLS QASGGSSNIR QEPTPKGRPA 900

LQLPGSSSHL RRALAEALNL RGQRNQTTFL TFH 933

Nucleotide Sequence
(FASTA)

ATGAAGATTC CTAACATTGG TAATGTGATG AATAAATTTG AGATCCTTGG GGTTGTAGGT 60

GAAGGAGCCT ATGGAGTTGT ACTTAAATGC AGACACAAGG AAACGCATGA AATTGTGGCA 120

ATCAAGAAAT TCAAGGACAG TGAAGAAAAT GAAGAAGTCA AGGAAACGAC TTTACGAGAG 180

CTTAAAATGC TTCGTACTCT CAAGCAGGAA AACATCGTGG AGCTGAAGGA AGCCTTTCGT 240

CGGAGGGGGA AATTGTACTT GGTGTTTGAG TATGTTGAAA AAAATATGCT TGAATTGCTG 300

GAAGAAATGC CAAATGGAGT TCCACCTGAA AAAGTTAAAA GTTATATCTA TCAGTTAATC 360

AAAGCTATTC ACTGGTGCCA TAAGAATGAT ATTGTCCATA GAGATATAAA GCCAGAAAAT 420

CTCTTAATCA GCCACAATGA TGTTTTGAAA CTGTGTGATT TTGGTTTTGC TCGGAACCTA 480

TCAGAAGGCA ATAATGCTAA TTATACAGAA TATGTGGCCA CCAGGTGGTA TCGGTCCCCA 540

GAACTCTTAC TTGGAGCTCC TTATGGAAAG TCTGTCGATA TGTGGTCAGT GGGCTGTATT 600

CTTGGGGAGC TTAGCGATGG ACAACCTTTA TTTCCTGGAG AAAGCGAAAT TGACCAACTT 660

TTTACTATTC AGAAGGTGCT AGGACCACTT CCATCTGAAC AGATGAAGCT CTTCTACAGT 720

AATCCTCGAT TCCATGGGCT CCGGTTTCCA GCTGTTAACC ACCCTCAGAC ATTGGAGAGA 780

AGATACCTTG GAATTCTAAA TAGCGTCTTA CTTGACTTAA TGAAGAATTT ACTGAAGTTG 840

GACCCAGCTG ACAGATACTT GACAGAACAA TGTTTGAATC ACCCTACATT TCAAACCCAG 900

AGACTTTTGG ATCGCTCCCC TTCAAGGTCA GCAAAAAGAA AACCTTACCA CGTGGAAAGC 960

AGCACTTTGT CTAATAGAAA TCAAGCCAGC AAAAGTGCTG CTTTGCAGTC TCACCACAGA 1020

TCCAACAGCA AGGACATCCA GAACCTAGGT GTGGGTTTGC CCCGGGCTGA CGAAGGTCTT 1080

CCTGCCAATG AAAGCTTCCT AAACGGAAAT CTTGCTGGAG CTACTCTTAG TCCCATGCAC 1140

ACCAAAACCT ACCAAGCAAG CAGCCAGCCT GGTTCTACCA GCAAAGATCT TACCAACAAT 1200

AACATACCAC ACCTTCTCAG CCCAAAAGAA GCCAAGTCAA AGACAGAGTT TGACTTCAAT 1260

ATTGACCCAA AGCCTTCAGA AGGCCCAGGC ACAAAGTACC TCAAGTCAAG CAGCAGATCT 1320

CAGCAGAACC GGCACTCATT CATGGAAAGC TCTCAGAGCA AAGCTGGGAC ACTGCAGCCC 1380

ACTGAAAAGC AGAGCCGGCA TAGCTACATT GACACTATTC CCCAGTCCTC TAGGAGTCCC 1440

TCCTACAGGA CCAAGGCCAA AAGCCACGGG GCGTTGAGTG ACTCCAAATC TGTGAGCAAC 1500

CTTTCCGAAG CCAGGGCCCA AATTGCAGAG TCCAATACCA ATAGGTACTT CCCATCCAGC 1560

TGCTTGGACT TGAACTCTCC CACCAGCCCA ACTCCCACCA GGCACAGTGA CACAAGAACT 1620

TTGCTCAGCC CCTCGGGGAG AAATAATCGA AGTGAGGGCA CTCTGGACTC ACGCCGAACC 1680

GCAACCAGGC ATTCCAAAAC CATGGAGGAG TTGAAGCTGC CTGAGCACAT GGACAGCAGC 1740

CATTCCCATT CTCTCTCTGC ACCTCATGAA TCCTTTTCTT ACGGGCTGGG CTACACTAGC 1800

CCCTTCTCTT CCCAGCAGCG TCCACATAGG CATTCCATGT ACGTGACCCG GGACAAAGTG 1860

AGAGCCAAAG GCTTGGACGG AAGCTTGAGC GTAGGGCAAG GAATGGCGGC CAGGGCCAAC 1920

AGCCTCCAGC TCTTATCACC TCAGCCTGGA GAACAGCTCC CTCCAGAGAT GACTGTGGCT 1980

CGATCTTCTG GTAAAGAATC TTCCAGAGAA GGCACTACTT CATTCCACGC AAGGCAGAAG 2040

TCTGAGGGTG GAGCATATCA TGACCCCCAC TCTGATGACG GCACCGCCCC CAAAGAAAAT 2100

AGACACCTGT ACAATGACCC TGTTCCAAGG AGAGTTGGTA GTTTCTACCG AGTGCCATCT 2160

CCTCGTCCAG ACAATTCTTT CCATGAAAAT AATGTATCAA CCAGAGTTTC TTCGCTACCA 2220

TCAGAGAGCA GTTCTGGAAC GAACCACTCA AAAAGACAAC CAGCATTCGA TCCATGGAAA 2280

AGTCCTGAAA ACATTAGTCA TTCCGAACAA CTCAAGGAAA AGGAGAAACA AGGTTTTTTC 2340

AGGTCAATGA AAAAGAAAAA GAAGAAATCT CAAACAGTGC CCAATTCTGA TGGCCCTGAT 2400

CTACTGACAT TACAGAAAGC CATTCATTCT GCTAGCACCC CGAGCAGCAG ACCGAAGGAG 2460

TGGCGTCCAG AGAAGATCTC TGATCTGCAG ACCCAAAGCC AGCCGTTAAA ATCACTGCGC 2520

AAGCTGTTAC ATCTCTCTTC AGCCTCAAAT CACCCGGCTT CCTCAGACCC CCGCTTCCAG 2580

CCCTTAACAA CTCAACAAGC CAAAAATTCC TTCTCAGAAA TTCGGATCCA CCCTCTGAGC 2640

CAGGCCTCTG GCGGGAGCAG TAACATCCGG CAGGAGCCCA CACCTAAGGG CAGACCAGCC 2700

CTCCAGCTGC CAGGCTCTTC TTCCCACCTA AGGCGGGCTC TGGCAGAAGC GCTGAATCTC 2760

AGGGGCCAGA GAAACCAAAC AACGTTCTTA ACATTCCACT GA 2802

Domain Profile

S: 1     yeklgkvGeGsyGvvlkcrnkdtgqivaikkfleseddkevkkialreikllkqlkhenl  60

         +e lg+vGeG+yGvvlkcr+k+t++ivaikkf++se+++evk+++lre+k+l++lk+en+

Q: 13    FEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENI  72

         799*********************************************************

S: 61    vnllevfrrkkklylvfeyvdktvldelerypnGveeelvkkilyqilkaiefchknnii  120

         v+l+e+frr+ klylvfeyv+k++l+ le++pnGv+ e+vk+++yq++kai++chkn+i+

Q: 73    VELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIV  132

         ************************************************************

S: 121   hrdikpenilisksgvvklcdfGfarlla.apgdvytdyvatrwyrapellvgdtkyGks  179

         hrdikpen+lis+++v+klcdfGfar+l+ +++++yt+yvatrwyr+pell+g + yGks

Q: 133   HRDIKPENLLISHNDVLKLCDFGFARNLSeGNNANYTEYVATRWYRSPELLLG-APYGKS  191

         ****************************98999********************.9*****

S: 180   vdvwaiGcllaelltGeplfpgksdvdqlykirktlGeliprhqkifsknevfaGvklpe  239

         vd+w++Gc+l el++G+plfpg+s++dql++i+k+lG+l ++++k+f++n++f+G+++p+

Q: 192   VDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPA  251

         ************************************************************

S: 240   vedleslekkyp.klnevlldllkkclkldpaerlsceellkheyf  284

         v+++++le++y   ln+vlldl+k++lkldpa+r+++e++l+h++f

Q: 252   VNHPQTLERRYLgILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTF  297

         ***********9899****************************998

Domain Sequence
(FASTA)

FEILGVVGEG AYGVVLKCRH KETHEIVAIK KFKDSEENEE VKETTLRELK MLRTLKQENI 60

VELKEAFRRR GKLYLVFEYV EKNMLELLEE MPNGVPPEKV KSYIYQLIKA IHWCHKNDIV 120

HRDIKPENLL ISHNDVLKLC DFGFARNLSE GNNANYTEYV ATRWYRSPEL LLGAPYGKSV 180

DMWSVGCILG ELSDGQPLFP GESEIDQLFT IQKVLGPLPS EQMKLFYSNP RFHGLRFPAV 240

NHPQTLERRY LGILNSVLLD LMKNLLKLDP ADRYLTEQCL NHPTF 285

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Ciona savignyi"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>