EPS-MUP-00102

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MUP-00102

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
DSP/PRL	161.3	3.9E-48	84	150	67

Status

Unreviewed

Ensembl Protein

ENSMPUP00000003087

UniProt Accession

G9KJ87;

Protein Name

Protein Synonyms/Alias

Protein tyrosine phosphatase 4a1;

Gene Name

PTP4A1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000003118	ENSMPUP00000003087	ENSMPUT00000003150

Organism

Mustela putorius furo

Functional Description

Protein Length

174

Protein Sequence
(FASTA)

INMARMNRPA PVEVTYKNMR FLITHNPTNA TLNKFIEELK KYGVTTIVRV CEATYDTTLV 60

EKEGIHVLDW PFDDGAPPSN QIVDDWLSLV KIKFREEPGC CIAVHCVAGL GRAPVLVALA 120

LIEGGMKYED AVQFIRQKRR GAFNSKQLLY LEKYRPKMRL RFKDSNGHRN NCCI 174

Nucleotide Sequence
(FASTA)

ATTAACATGG CTCGAATGAA CCGCCCAGCT CCTGTGGAAG TCACATACAA GAACATGAGA 60

TTTCTTATTA CACACAATCC AACCAATGCG ACCTTAAACA AATTTATAGA GGAACTTAAG 120

AAGTATGGTG TTACAACTAT AGTAAGAGTA TGTGAAGCAA CTTACGACAC TACTCTTGTG 180

GAGAAAGAAG GCATCCATGT TCTTGATTGG CCTTTTGATG ATGGTGCACC ACCATCTAAC 240

CAGATTGTTG ATGACTGGTT AAGTCTTGTA AAAATTAAGT TTCGTGAAGA ACCTGGTTGT 300

TGTATTGCTG TTCATTGTGT TGCAGGCCTT GGGAGAGCTC CAGTGCTTGT TGCCCTAGCA 360

TTAATTGAAG GTGGAATGAA ATATGAAGAT GCAGTACAGT TCATAAGACA AAAGCGGCGT 420

GGAGCTTTTA ACAGCAAGCA ACTTTTGTAT TTGGAGAAGT ATCGTCCTAA AATGCGGCTG 480

CGCTTCAAAG ACTCCAATGG TCATAGAAAC AACTGTTGCA TT 522

Domain Profile

S: 1     ddwlslvkikfreepGsciavhcvaGlGrapvlvalaliesGmkyedavqfirqkrrGai  60

         ddwlslvkikfreepG+ciavhcvaGlGrapvlvalalie+GmkyedavqfirqkrrGa+

Q: 84    DDWLSLVKIKFREEPGCCIAVHCVAGLGRAPVLVALALIEGGMKYEDAVQFIRQKRRGAF  143

         8***********************************************************

S: 61    nskqlly  67

         nskqlly

Q: 144   NSKQLLY  150

         ******9

Domain Sequence
(FASTA)

DDWLSLVKIK FREEPGCCIA VHCVAGLGRA PVLVALALIE GGMKYEDAVQ FIRQKRRGAF 60

NSKQLLY 67

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Choloepus hoffmanni"; ?>Danio rerio"; ?>Dasypus novemcinctus"; ?>Drosophila melanogaster"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Erinaceus europaeus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Macropus eugenii"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Procavia capensis"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tarsius syrichta"; ?>Tetraodon nigroviridis"; ?>Tupaia belangeri"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005737	; C:cytoplasm
GO:0009898	; C:internal side of plasma membrane
GO:0008138	; F:protein tyrosine/serine/threonine phosphatase activity
GO:0030335	; P:positive regulation of cell migration
GO:0006470	; P:protein dephosphorylation

KEGG

InterPros

IPR000340	; Dual-sp_phosphatase_cat-dom.
IPR000387	; Tyr/Dual-specificity_Pase.

Pfam

PF00782

; DSPc; 1.

SMARTs

Prosites

PS50056

; TYR_PHOSPHATASE_2; 1.

Prints

Created Date

20-Feb-2013