EKS-MUP-00265

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00265

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CMGC/DYRK	453.8	3.2E-136	190	518	329

Status

Unreviewed

Ensembl Protein

ENSMPUP00000005316

Gene Name

Hipk1

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000005355	ENSMPUP00000005316	ENSMPUT00000005405

Organism

Mustela putorius furo

Protein Length

1210

Protein Sequence
(FASTA)

MASQLQVFSP PSVSSSAFCS AKKLKIEPSG WDVSGQSSND KYYTHSKTLP ATQGQANSSH 60

QVANFNIPAY DQGLLLPAPA VEHIVVTAAD SSASAAPSTF QSSQTLTHRN NVSLLEPYQK 120

CGLKRKSEEV DSNGSVQIIE EHPPLMLQNR TVVGAAATTT TVTTKSSSSS GEGDYQLVQH 180

EILCSMTNSY EVLEFLGRGT FGQVAKCWKR STKEIVAIKI LKNHPSYARQ GQIEVSILSR 240

LSSENADEYN FVRSYECFQH KNHTCLVFEM LEQNLYDFLK QNKFSPLPLK YIRPILQQVA 300

TALMKLKSLG LIHADLKPEN IMLVDPVRQP YRVKVIDFGS ASHVSKAVCS TYLQSRYYRA 360

PEIILGLPFC EAIDMWSLGC VIAELFLGWP LYPGASEYDQ IRYISQTQGL PAEYLLSAGT 420

KTTRFFNRDP NLGYPLWRLK TPEEHELETG IKSKEARKYI FNCLDDMAQV NMSTDLEGTD 480

MLAEKADRRE YIDLLKKMLT IDADKRITPL KTLNHQFVTM THLLDFPHSN HVKSCFQNME 540

ICKRRVHMYD TVSQIKSPFT THVAPNTSTN LTMSFSNQLN TVHNQASVLA SSSTAAAATL 600

SLANSDVSLL NYQSALYPSS AAPVPGVAQQ GVSLQPGTTQ ICTQTDPFQQ TFIVCPPAFQ 660

TGLQATTKHS GFPVRMDNAV PIVPQAPAAQ PLQIQSGVLT QGSCTPLMVA TLHPQVATIA 720

PQYAVPFTLS CAAGRPALVE QTAAVLQAWP GGTQQILLPS TWQQLPGVAL HNSVQPTAVI 780

PEAMGSGQQL TDWRNAHSHG NQYSTIMQQP SLLTNHVTLA TAQPLNVGVA HVVRQPQSSS 840

LPSKKNKQSA PVSSKSSLDV LPSQVYSLVG SSPLRTTSSY NSLVPVPDQH QPIIIPDTPS 900

PPVSVITIRS DTDEEEDNKY KPNSSGLKAR SNVISYVTVN DSPDSDSSLS SPYSTDTLSA 960

LRGNSGPLVE GPGRVAGDGT GTRTIIVPPL KTQLGDCTGA APASGLVSSK TKPVASVSGQ 1020

SSGCCITPTG YRAPRGGTSA AQPLNLSQNQ QSSSAPTSQE RSSNPAPRRQ QAFVAPLSQA 1080

PYAFQHGSPL HSTGHPHLAP APAHLPSQPH LYTYAAPTSA AALGSTSSIA HLFSPQGSSR 1140

HAAAYSTHPS TLVHQVPVSV GPSLLTSASV APAQYQHQFA TQSYIGSSRG STIYTGYPLS 1200

PTKISQYSYL 1210

Nucleotide Sequence
(FASTA)

ATGGCATCAC AGCTGCAGGT GTTTTCCCCC CCATCAGTGT CGTCGAGTGC CTTCTGCAGT 60

GCGAAGAAAC TGAAAATAGA GCCCTCTGGC TGGGATGTTT CTGGACAGAG CAGCAACGAC 120

AAATATTATA CCCACAGCAA AACCCTCCCA GCCACACAAG GGCAAGCCAA CTCCTCTCAC 180

CAGGTAGCAA ATTTCAACAT CCCTGCCTAC GACCAGGGCC TCCTCCTTCC AGCTCCTGCA 240

GTGGAGCATA TTGTTGTAAC AGCTGCTGAT AGCTCGGCCA GTGCTGCTCC ATCAACCTTC 300

CAAAGCAGCC AGACCCTGAC TCACAGAAAC AACGTTTCTT TGCTTGAGCC ATATCAAAAA 360

TGTGGATTGA AAAGAAAAAG TGAGGAAGTT GACAGCAACG GTAGCGTGCA AATCATAGAA 420

GAACATCCCC CTCTCATGCT GCAAAACAGG ACTGTGGTGG GTGCTGCTGC CACGACCACC 480

ACTGTGACCA CAAAGAGTAG CAGTTCCAGT GGAGAAGGGG ACTACCAGCT GGTCCAGCAT 540

GAGATCCTTT GCTCTATGAC CAATAGCTAT GAAGTGTTGG AGTTCCTAGG CCGGGGAACA 600

TTTGGACAGG TGGCTAAGTG CTGGAAGCGG AGCACGAAGG AAATTGTGGC TATTAAAATC 660

TTGAAGAACC ACCCCTCCTA TGCCAGACAA GGACAGATTG AAGTGAGCAT CCTTTCTCGC 720

CTAAGCAGTG AAAATGCTGA TGAGTATAAT TTTGTTCGTT CTTATGAGTG CTTTCAGCAT 780

AAGAATCACA CCTGCCTTGT GTTTGAGATG CTGGAGCAGA ACTTGTATGA TTTTCTAAAG 840

CAGAACAAGT TTAGCCCACT GCCACTCAAG TACATCAGAC CAATCTTGCA GCAGGTGGCC 900

ACAGCCCTGA TGAAGCTCAA GAGCCTTGGT CTGATTCACG CTGACCTTAA GCCTGAAAAC 960

ATAATGCTGG TCGATCCAGT GCGCCAACCC TACCGAGTGA AGGTCATTGA CTTTGGTTCT 1020

GCTAGTCACG TTTCCAAAGC TGTGTGCTCA ACCTACTTAC AGTCACGTTA CTACAGAGCC 1080

CCTGAAATTA TTCTTGGATT ACCGTTTTGT GAAGCTATTG ATATGTGGTC ATTGGGCTGT 1140

GTGATAGCTG AGCTGTTCCT GGGATGGCCT CTTTATCCTG GTGCTTCAGA ATATGATCAG 1200

ATTCGTTACA TTTCACAAAC ACAAGGCCTG CCCGCTGAAT ATCTTCTCAG TGCTGGGACA 1260

AAAACAACGA GGTTTTTCAA CAGAGATCCT AATTTGGGGT ATCCGCTGTG GAGGCTTAAG 1320

ACACCAGAAG AACATGAATT GGAGACTGGA ATCAAATCAA AAGAAGCTCG AAAGTACATT 1380

TTTAATTGTT TAGATGACAT GGCTCAGGTA AATATGTCCA CAGACTTGGA GGGAACAGAT 1440

ATGTTGGCAG AGAAGGCGGA TCGAAGAGAA TATATTGATC TGTTAAAAAA AATGCTAACA 1500

ATTGATGCAG ATAAGAGAAT TACTCCTCTG AAAACTCTTA ACCATCAATT TGTGACAATG 1560

ACCCACCTTC TGGATTTTCC ACATAGCAAT CATGTTAAGT CCTGTTTTCA GAACATGGAG 1620

ATCTGCAAGC GGAGGGTTCA CATGTATGAT ACAGTGAGTC AGATCAAGAG TCCCTTCACT 1680

ACTCACGTTG CCCCAAATAC AAGCACAAAT CTAACCATGA GCTTCAGCAA CCAGCTTAAT 1740

ACAGTGCACA ATCAGGCCAG TGTTCTAGCT TCCAGTTCTA CTGCAGCAGC TGCTACTCTT 1800

TCCCTGGCTA ATTCAGATGT CTCATTGCTA AACTACCAGT CGGCTTTGTA TCCATCGTCT 1860

GCAGCACCAG TTCCTGGAGT TGCCCAGCAG GGCGTGTCCT TGCAGCCTGG AACCACCCAA 1920

ATTTGCACTC AGACAGATCC GTTCCAACAA ACATTTATAG TATGTCCACC TGCTTTTCAG 1980

ACTGGACTAC AAGCAACAAC AAAACACTCT GGATTCCCTG TGAGGATGGA TAACGCTGTG 2040

CCGATTGTAC CCCAGGCGCC AGCCGCGCAG CCACTGCAGA TCCAGTCAGG AGTGCTGACG 2100

CAGGGAAGCT GTACACCACT AATGGTAGCA ACTCTCCACC CTCAAGTAGC CACCATCGCA 2160

CCGCAGTATG CGGTGCCCTT TACTCTGAGC TGCGCAGCCG GCCGGCCGGC GCTGGTTGAA 2220

CAGACTGCCG CTGTACTGCA GGCTTGGCCT GGAGGAACCC AACAAATTCT CCTGCCTTCA 2280

ACTTGGCAAC AGTTGCCTGG GGTAGCTCTG CACAACTCTG TCCAACCCAC AGCAGTCATT 2340

CCAGAGGCCA TGGGCAGTGG CCAGCAGCTC ACAGACTGGA GGAATGCCCA CTCTCATGGC 2400

AACCAGTACA GCACTATCAT GCAGCAGCCC TCCTTGCTGA CTAACCACGT GACGCTGGCC 2460

ACTGCTCAGC CCCTGAATGT TGGTGTTGCC CATGTTGTCA GACAACCACA ATCCAGTTCT 2520

CTCCCTTCTA AGAAGAATAA GCAATCTGCT CCAGTCTCTT CTAAGTCTTC GCTGGATGTT 2580

CTGCCTTCTC AAGTCTATTC TCTAGTTGGG AGCAGTCCTC TCCGTACCAC ATCTTCTTAT 2640

AATTCCCTAG TCCCTGTCCC AGATCAGCAT CAGCCAATCA TCATTCCAGA TACTCCCAGC 2700

CCTCCTGTGA GTGTCATCAC CATCCGCAGT GACACCGATG AGGAAGAAGA CAATAAGTAC 2760

AAGCCCAATA GCTCTGGCCT GAAGGCAAGG TCTAACGTCA TCAGTTATGT CACTGTCAAT 2820

GATTCTCCAG ACTCTGACTC TTCCTTGAGC AGCCCATATT CCACTGATAC CCTGAGTGCT 2880

CTCCGGGGCA ACAGTGGACC CCTGGTGGAG GGGCCTGGCA GAGTCGCGGG GGATGGCACC 2940

GGCACCCGCA CCATCATTGT ACCTCCACTG AAAACTCAGC TCGGTGACTG CACTGGGGCA 3000

GCCCCAGCCT CAGGTCTTGT GAGCAGTAAG ACCAAGCCAG TGGCCTCAGT GAGTGGGCAG 3060

TCATCTGGAT GCTGTATCAC CCCCACAGGG TATCGAGCTC CACGCGGGGG GACCAGCGCA 3120

GCACAGCCAC TCAACCTTAG CCAGAACCAG CAGTCATCGT CAGCTCCAAC CTCGCAGGAG 3180

AGAAGCAGCA ACCCTGCCCC CCGCAGGCAG CAGGCGTTTG TGGCCCCGCT CTCCCAGGCC 3240

CCCTACGCCT TCCAGCATGG CAGCCCACTA CACTCGACGG GGCACCCACA CCTGGCCCCA 3300

GCCCCTGCTC ACCTGCCGAG CCAGCCTCAC CTGTATACGT ATGCTGCCCC CACCTCTGCT 3360

GCTGCATTGG GCTCCACCAG CTCCATTGCT CATCTCTTCT CTCCCCAGGG CTCCTCAAGG 3420

CATGCTGCAG CCTATAGCAC CCACCCTAGC ACTCTGGTGC ACCAGGTCCC TGTCAGCGTT 3480

GGGCCCAGCC TTCTCACTTC TGCCAGTGTG GCCCCTGCTC AGTACCAACA CCAGTTTGCC 3540

ACCCAGTCCT ACATTGGGTC TTCCCGAGGC TCAACAATTT ACACTGGATA CCCACTGAGT 3600

CCGACCAAGA TCAGCCAGTA TTCCTATTTG TAG 3633

Domain Profile

S: 1     yevlevigkGsfgqVvkaldkktkeivaikiiknkkrfarqaqeEveiLeklnkkdkeek  60

         yevle++g+G+fgqV+k+++++tkeivaiki+kn++++arq+q+Ev+iL++l++ +++++

Q: 190   YEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSS-ENADE  248

         9****************************************************9.999**

S: 61    ynvvrllelfvfrnhlclvfellsqnLyellkknkfsglslklvrklaqqilkaLklLke  120

         yn+vr +e+f+++nh+clvfe+l+qnLy++lk+nkfs+l+lk++r+++qq+++aL++Lk+

Q: 249   YNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKS  308

         ************************************************************

S: 121   lkiiHaDlKPeNillvekkrse..vkviDFGsssavsqkeiytyiqsrfYraPEiilglk  178

         l++iHaDlKPeNi+lv++ r++  vkviDFGs+s+vs+++++ty+qsr+YraPEiilgl+

Q: 309   LGLIHADLKPENIMLVDPVRQPyrVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLP  368

         *********************999************************************

S: 179   ydeaiDmWSlGcvlaElftGkpLfpGenevdqlalivevlglppekllekakkakkff..  236

         ++eaiDmWSlGcv+aElf+G+pL+pG++e+dq+++i++++glp+e+ll++++k+++ff

Q: 369   FCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFnr  428

         **********************************************************66

S: 237   .tkkeapkyilktk.........ksdrkkklvlnvkkaakkrkaplskelgealkekedk  286

           + ++p ++lkt          ks++++k+++n+ +++++++++++ e +++l+ek+d+

Q: 429   dPNLGYPLWRLKTPeeheletgiKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADR  488

         556778889998889********************************************9

S: 287   l.fkdllkrmleldpakRitpkealkhpfv  315

         + ++dllk+ml++d++kRitp ++l+h+fv

Q: 489   ReYIDLLKKMLTIDADKRITPLKTLNHQFV  518

         99***************************7

Domain Sequence
(FASTA)

YEVLEFLGRG TFGQVAKCWK RSTKEIVAIK ILKNHPSYAR QGQIEVSILS RLSSENADEY 60

NFVRSYECFQ HKNHTCLVFE MLEQNLYDFL KQNKFSPLPL KYIRPILQQV ATALMKLKSL 120

GLIHADLKPE NIMLVDPVRQ PYRVKVIDFG SASHVSKAVC STYLQSRYYR APEIILGLPF 180

CEAIDMWSLG CVIAELFLGW PLYPGASEYD QIRYISQTQG LPAEYLLSAG TKTTRFFNRD 240

PNLGYPLWRL KTPEEHELET GIKSKEARKY IFNCLDDMAQ VNMSTDLEGT DMLAEKADRR 300

EYIDLLKKML TIDADKRITP LKTLNHQFV 329

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Echinops telfairi"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Tursiops truncatus"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>