EPS-MUP-00022

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MUP-00022

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	195.4	1.4E-57	60	317	258

Status

Unreviewed

Ensembl Protein

ENSMPUP00000005846

UniProt Accession

G9KI41;

Protein Name

Protein Synonyms/Alias

Protein phosphatase 1B, magnesium dependent, beta isoform;

Gene Name

PPM1N

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000005895	ENSMPUP00000005846	ENSMPUT00000005948

Organism

Mustela putorius furo

Functional Description

Protein Length

423

Protein Sequence
(FASTA)

MAAFARLLER LLWPASKKQE SEEEEEEGHR THHEPQSLLD APRCVQRPHG GAAASCGLSF 60

GASAVQGWRA HMEDAHCVWL ALPGLPPGWA FFAVLDGHGG TRAALFGARH LPDHVLQALG 120

PAPGEPEGVR GALRQAFLSA DERLRALWPR GEPGGSTALA LLVSPRFLYL AHCGDSRAML 180

SRAGAMAFST EDHRPLRPRE RERIHNAGGT ICRRRLEGSL AVSRALGDFA YKEAPGRPPE 240

LQLVSAEPEV TALARQAEDE FVLLASDGVW DAMSGAALAG LVASRLYLGL APELLCAQLL 300

DTCLCKGSLD NMTCILICFP GAPKPCEEAI RKELALDAAL GRRVAELCSS AQEPPSLNTV 360

FWTLAAEDIP DLPPGGGLYC KATVIAEAYS RLRQASGRRW QKGPRGAGKP TGTLSDSSLD 420

SEA 423

Nucleotide Sequence
(FASTA)

ATGGCTGCCT TCGCCCGCCT GCTGGAGCGT CTCCTCTGGC CAGCCTCTAA AAAACAGGAG 60

TCAGAAGAGG AAGAGGAGGA GGGGCACAGG ACTCACCACG AACCTCAGTC GCTCCTGGAC 120

GCGCCGCGAT GCGTCCAGCG GCCGCACGGG GGTGCGGCAG CGTCTTGCGG CCTGAGCTTC 180

GGGGCGAGCG CTGTGCAAGG CTGGCGCGCG CACATGGAGG ATGCGCACTG CGTTTGGCTC 240

GCGCTGCCCG GGCTACCTCC AGGCTGGGCA TTCTTTGCGG TCCTCGACGG CCACGGCGGG 300

ACGCGAGCTG CCCTCTTCGG CGCGCGCCAC TTGCCGGACC ACGTGCTCCA GGCACTGGGC 360

CCGGCGCCTG GCGAACCCGA GGGAGTGCGC GGGGCGCTAC GCCAAGCCTT CCTGAGCGCA 420

GACGAACGGC TGCGTGCGCT CTGGCCTCGG GGCGAGCCGG GGGGCTCCAC CGCCTTGGCG 480

TTGCTCGTCT CCCCGCGTTT TCTGTACCTG GCGCACTGCG GTGACTCCCG AGCGATGCTG 540

AGTCGCGCCG GTGCCATGGC CTTCAGCACC GAGGACCATC GGCCCCTCCG GCCCCGGGAA 600

CGGGAGCGCA TCCACAACGC GGGAGGCACC ATCTGCCGCC GGCGCCTCGA AGGCTCTCTG 660

GCAGTATCCC GAGCGCTGGG CGACTTTGCT TACAAAGAGG CTCCGGGAAG GCCCCCTGAG 720

TTGCAGCTCG TTTCCGCGGA GCCTGAGGTG ACCGCCCTGG CTCGCCAGGC TGAGGACGAG 780

TTCGTGCTGT TGGCCTCTGA CGGTGTGTGG GACGCGATGT CTGGTGCTGC CCTGGCGGGA 840

CTGGTGGCGT CGCGCCTCTA CTTAGGCCTG GCCCCGGAGC TTCTCTGCGC GCAGCTATTG 900

GACACGTGTC TGTGCAAGGG CAGCCTGGAC AACATGACCT GCATCCTGAT CTGCTTCCCT 960

GGGGCCCCGA AGCCTTGTGA GGAGGCGATC AGGAAGGAGC TGGCGCTGGA TGCAGCCCTG 1020

GGCCGCAGGG TCGCCGAGCT GTGTTCGTCT GCTCAGGAGC CCCCCAGCCT GAACACGGTT 1080

TTCTGGACTC TAGCCGCAGA GGACATCCCA GACTTACCTC CTGGGGGAGG GCTGTACTGC 1140

AAGGCCACGG TCATTGCTGA AGCTTATTCT CGGCTCCGCC AAGCCTCAGG ACGCCGCTGG 1200

CAGAAGGGCC CACGTGGGGC AGGAAAGCCC ACTGGCACCC TTTCGGACTC TTCCTTGGAC 1260

TCGGAGGCCT GA 1272

Domain Profile

S: 3     vgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheila  62

         +g ++v+g+r +meda+ +   +   p     +aff+v DGhgg+++a f + +l +++

Q: 60    FGASAVQGWRAHMEDAHCVWLALPGLPP---GWAFFAVLDGHGGTRAALFGARHLPDHVL  116

         68899************88555555544...4****************************

S: 63    eelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikdsklyvanv  122

         + l    +e + v+ al++aFls de+l    +   + ++ Gsta+  l+++  ly a++

Q: 117   QALGPAPGEPEGVRGALRQAFLSADERL---RALWPRGEPGGSTALALLVSPRFLYLAHC  173

         ****999*********************...555556999********************

S: 123   GdSravLcrngkavelssdHkpsredEleRieeaggsvilkdgaRvlGvLavsRalGdly  182

         GdSra+L+r g +   ++dH+p r++E+eRi +agg++ ++   R+ G+LavsRalGd+

Q: 174   GDSRAMLSRAGAMAFSTEDHRPLRPRERERIHNAGGTICRR---RLEGSLAVSRALGDFA  230

         ***********999*************************99...****************

S: 183   lk.........pyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekke  233

         +k         ++v++ePevt   ++ edef+ LasDG+wd +s  ++  lv ++l  +

Q: 231   YKeapgrppelQLVSAEPEVTALARQAEDEFVLLASDGVWDAMSGAALAGLVASRLYLGL  290

         ************************************************************

S: 234   aeqeaakkLvklalargskdnvsaivv  260

         a++  + +L++++l +gs dn++ i++

Q: 291   APELLCAQLLDTCLCKGSLDNMTCILI  317

         **********************99876

Domain Sequence
(FASTA)

FGASAVQGWR AHMEDAHCVW LALPGLPPGW AFFAVLDGHG GTRAALFGAR HLPDHVLQAL 60

GPAPGEPEGV RGALRQAFLS ADERLRALWP RGEPGGSTAL ALLVSPRFLY LAHCGDSRAM 120

LSRAGAMAFS TEDHRPLRPR ERERIHNAGG TICRRRLEGS LAVSRALGDF AYKEAPGRPP 180

ELQLVSAEPE VTALARQAED EFVLLASDGV WDAMSGAALA GLVASRLYLG LAPELLCAQL 240

LDTCLCKGSL DNMTCILI 258

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Felis catus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Macaca mulatta"; ?>Mus musculus"; ?>Nomascus leucogenys"; ?>Oryctolagus cuniculus"; ?>Otolemur garnettii"; ?>Pteropus vampyrus"; ?>Rattus norvegicus"; ?>Sorex araneus"; ?>

Gene Ontology

GO:0000287	; F:magnesium ion binding
GO:0030145	; F:manganese ion binding
GO:0004721	; F:phosphoprotein phosphatase activity
GO:0008152	; P:metabolic process

KEGG

InterPros

IPR001932	; PP2C-like.
IPR012911	; PP2C_C.
IPR015655	; Protein_Pase_2C.

Pfam

PF00481	; PP2C; 1.
PF07830	; PP2C_C; 1.

SMARTs

SM00332

; PP2Cc; 1.

Prosites

Prints

Created Date

20-Feb-2013