EKS-MUP-00166

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00166

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
CAMK/RSKb	489.1	2.8E-147	409	666	258

Status

Unreviewed

Ensembl Protein

ENSMPUP00000006238

UniProt Accession

G9KLV1;

Protein Name

Protein Synonyms/Alias

Ribosomal protein S6 kinase, 90kDa, polypeptide 6;

Gene Name

Rps6ka6

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000006292	ENSMPUP00000006238	ENSMPUT00000006347

Organism

Mustela putorius furo

Functional Description

Protein Length

794

Protein Sequence
(FASTA)

MEVFRGGARS GEVDGVQIVD EPMEEEADSC QDEGVVKEIP ITHHVKEGYE KADPAQFELL 60

KVLGQGSFGK VFLVRKKTGP DAGQLYAMKV LKKASLKVRD RVRTKMERDI LVEVNHPFIV 120

KLHYAFQTEG KLYLILDFLR GGDVFTRLSK EVLFTEEDVK FYLAELALAL DHLHQLGIVY 180

RDLKPENILL DEIGHIKLTD FGLSKESVDQ EKKAYSFCGT VEYMAPEIVN RRGHSQSADW 240

WSYGVLMFEM LTGTLPFQGK DRNETMNMIL KAKLGMPQFL SAEAQSLLRM LFKRNPANRL 300

GSEGVEEIKR HLFFANVDWN KLYRREVQPP FKPASGKPDD TFCFDPEFTA KTPKDSPGLP 360

ASANAHQLFK GFSFVATSIA EEYKVTPVTS ANVLPVQING NAAQFGEVYE LKEDIGVGSY 420

SVCKRCIHTA TNMEFAVKII DKSKRDPSEE IEILMRYGQH PNVITLKDVY DDGRYVYLVT 480

DLMKGGELLD RILKKKCFSE REASDVLIVI TKTVDYLHCQ GVVHRDLKPS NILYMDESGN 540

ADSIRICDFG FAKQLRGENG LLLTPCYTAN FVAPEVLMQQ GYDAACDIWS LGVLFYTMLA 600

GYTPFANGPN DTPEEILLRI GNGKFSLTGG NWDNISDGAK DLLSHMLHMD PHQRYTTEQV 660

LKHSWITHRN RLLNDQPNRN DTSDVIKGAV VTTYSALTHK TFQPVLEPVA ASNLAQRRSM 720

KKRTSTGLQS NQTRTTLSVI IRENISGQGI YAVCPRIRLS HKLLRWCTAS SFLLLDILFF 780

LQETSKLFNH NELM 794

Nucleotide Sequence
(FASTA)

ATGGAGGTTT TCCGAGGCGG CGCGAGGAGC GGCGAGGTGG ATGGTGTACA GATTGTTGAT 60

GAGCCGATGG AAGAAGAAGC AGATTCTTGC CAAGATGAAG GAGTTGTTAA AGAAATCCCT 120

ATCACTCATC ATGTTAAGGA AGGTTATGAG AAGGCAGATC CTGCGCAGTT TGAGTTGCTC 180

AAGGTTCTTG GCCAGGGATC CTTTGGAAAG GTTTTTCTTG TTCGGAAGAA GACCGGTCCT 240

GATGCTGGGC AGCTCTATGC AATGAAGGTG TTAAAAAAGG CTTCTTTAAA AGTCCGAGAC 300

AGAGTTCGGA CAAAGATGGA AAGGGATATA CTGGTGGAAG TAAATCATCC ATTTATTGTC 360

AAATTACACT ATGCCTTTCA GACTGAAGGG AAGCTGTATT TAATACTGGA TTTTCTCAGG 420

GGAGGAGATG TCTTCACAAG ATTATCCAAA GAGGTTCTGT TTACAGAGGA AGATGTGAAA 480

TTCTACCTTG CAGAACTGGC CCTTGCTTTG GATCATCTGC ACCAATTAGG AATTGTATAT 540

AGAGACCTGA AGCCAGAAAA CATTCTGCTT GATGAAATAG GACATATCAA GTTAACAGAT 600

TTTGGGCTCA GCAAGGAATC AGTAGATCAA GAAAAGAAGG CTTACTCATT TTGTGGTACA 660

GTGGAGTATA TGGCTCCTGA AATAGTAAAT CGGAGAGGAC ATTCCCAGAG TGCTGATTGG 720

TGGTCATATG GTGTACTTAT GTTTGAAATG CTTACTGGTA CTCTGCCATT TCAAGGTAAA 780

GACAGAAATG AGACCATGAA CATGATATTA AAAGCAAAAC TTGGGATGCC TCAATTTCTT 840

AGTGCTGAGG CACAAAGTCT TCTAAGGATG TTATTCAAAA GGAATCCAGC AAATAGATTG 900

GGTTCAGAAG GAGTTGAGGA AATTAAAAGA CATCTTTTTT TTGCAAATGT TGACTGGAAT 960

AAATTATATA GAAGAGAAGT TCAACCTCCT TTCAAACCTG CTTCTGGAAA ACCAGATGAT 1020

ACCTTTTGTT TTGATCCTGA ATTTACTGCA AAAACACCTA AAGATTCTCC TGGTTTGCCA 1080

GCTAGTGCTA ATGCTCATCA ACTCTTCAAA GGATTCAGCT TTGTTGCAAC TTCTATTGCG 1140

GAAGAATATA AAGTCACTCC TGTCACAAGT GCAAACGTGT TACCAGTTCA GATAAATGGA 1200

AATGCTGCAC AATTTGGTGA AGTATATGAA TTAAAAGAAG ATATAGGTGT TGGCTCCTAT 1260

TCTGTTTGCA AGCGATGCAT TCATACAGCT ACCAACATGG AATTTGCAGT GAAGATCATT 1320

GACAAAAGTA AGAGAGATCC CTCAGAAGAA ATTGAAATTT TGATGCGCTA TGGACAACAC 1380

CCCAACGTCA TTACTTTAAA GGATGTTTAT GATGATGGTA GATATGTTTA CCTTGTTACG 1440

GATTTGATGA AAGGAGGAGA ACTACTTGAC CGTATTCTCA AAAAAAAATG TTTCTCAGAA 1500

CGGGAAGCTA GTGATGTACT GATTGTAATA ACTAAGACAG TTGACTATCT TCATTGTCAA 1560

GGAGTTGTTC ATCGTGATCT TAAACCTAGT AATATTTTGT ATATGGATGA ATCAGGCAAC 1620

GCAGACTCCA TTAGAATCTG TGATTTTGGG TTTGCAAAAC AACTTCGAGG AGAAAATGGA 1680

CTTCTTTTAA CTCCATGCTA CACTGCAAAC TTTGTAGCAC CTGAGGTTCT TATGCAACAG 1740

GGCTATGATG CTGCTTGTGA TATTTGGAGC CTGGGTGTTC TTTTTTACAC AATGCTGGCT 1800

GGCTATACTC CATTTGCTAA TGGCCCCAAT GATACTCCTG AAGAGATACT GCTACGTATA 1860

GGCAATGGCA AGTTCTCATT GACTGGTGGA AACTGGGACA ATATTTCAGA TGGAGCAAAG 1920

GATTTGCTCT CCCATATGCT ACATATGGAC CCACATCAGC GGTACACTAC AGAACAAGTA 1980

TTAAAACACT CGTGGATAAC CCACAGAAAC CGCTTGCTGA ATGATCAGCC AAATAGAAAT 2040

GATACATCAG ATGTCATTAA GGGAGCAGTG GTCACCACAT ATTCTGCCCT GACTCACAAG 2100

ACCTTTCAAC CAGTCCTTGA GCCTGTTGCT GCTTCAAACT TAGCTCAACG ACGGAGCATG 2160

AAAAAACGAA CATCAACTGG CCTGCAATCT AACCAGACGA GAACAACTCT ATCAGTTATT 2220

ATCAGGGAAA ATATTTCTGG ACAAGGAATT TATGCAGTAT GCCCCAGGAT CAGATTATCT 2280

CATAAACTGC TGCGTTGGTG CACTGCTTCA TCCTTTCTAC TCCTCGATAT ACTTTTTTTC 2340

CTCCAAGAAA CTTCCAAGCT CTTTAATCAC AATGAACTTA TGTGA 2385

Domain Profile

S: 1     yevkedlGvGsysvckrcvhkatnqefavkiidkskrdtseeieillryeqhpnivtlkd  60

         ye+ked+GvGsysvckrc+h atn+efavkiidkskrd+seeieil+ry+qhpn++tlkd

Q: 409   YELKEDIGVGSYSVCKRCIHTATNMEFAVKIIDKSKRDPSEEIEILMRYGQHPNVITLKD  468

         789*********************************************************

S: 61    vyddgkyvylvlellkGGelldrikkkkffsereasailrtlvkaveylheqGvvhrdlk  120

         vyddg+yvylv++l+kGGelldri+kkk+fsereas++l +++k+v+ylh+qGvvhrdlk

Q: 469   VYDDGRYVYLVTDLMKGGELLDRILKKKCFSEREASDVLIVITKTVDYLHCQGVVHRDLK  528

         ************************************************************

S: 121   penilyvdesdnaesikiidfGfaklkraengllktpcytlnfvapevlkrqGydeacdl  180

         p+nily+des+na+si+i+dfGfak++r engll tpcyt+nfvapevl++qGyd+acd+

Q: 529   PSNILYMDESGNADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQGYDAACDI  588

         ************************************************************

S: 181   wslGvllytmlaGyvpfangpedtaeeilakikeGkfslsGeawdsvseeakdlvskllt  240

         wslGvl+ytmlaGy+pfangp+dt+eeil +i++Gkfsl G++wd++s+ akdl+s++l+

Q: 589   WSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLTGGNWDNISDGAKDLLSHMLH  648

         ************************************************************

S: 241   vdpakrlkleqllkhswl  258

         +dp++r++ eq+lkhsw+

Q: 649   MDPHQRYTTEQVLKHSWI  666

         *****************8

Domain Sequence
(FASTA)

YELKEDIGVG SYSVCKRCIH TATNMEFAVK IIDKSKRDPS EEIEILMRYG QHPNVITLKD 60

VYDDGRYVYL VTDLMKGGEL LDRILKKKCF SEREASDVLI VITKTVDYLH CQGVVHRDLK 120

PSNILYMDES GNADSIRICD FGFAKQLRGE NGLLLTPCYT ANFVAPEVLM QQGYDAACDI 180

WSLGVLFYTM LAGYTPFANG PNDTPEEILL RIGNGKFSLT GGNWDNISDG AKDLLSHMLH 240

MDPHQRYTTE QVLKHSWI 258

Keyword

Kinase; Transferase.

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Bos taurus"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gallus gallus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>

Gene Ontology

GO:0005524	; F:ATP binding
GO:0004672	; F:protein kinase activity
GO:0006978	; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

KEGG

InterPros

IPR011009	; Kinase-like_dom.
IPR000719	; Prot_kinase_cat_dom.

Pfam

PF00069

; Pkinase; 1.

SMARTs

Prosites

PS50011

; PROTEIN_KINASE_DOM; 1.

Prints

Created Date

20-Feb-2013