EPS-MUP-00024

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EPS-MUP-00024

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
PPM/PP2C	192.7	9.6E-57	778	1024	247

Status

Unreviewed

Ensembl Protein

ENSMPUP00000007833

Gene Name

PHLPP2

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000007891	ENSMPUP00000007833	ENSMPUT00000007958

Organism

Mustela putorius furo

Protein Length

1316

Protein Sequence
(FASTA)

MKRNGSRNCL NRRSRFGSRE RDWLREDVRR GCVYLYGADS TTATASASAS ASSDLHLVLC 60

TVETPASEIC AGEGRESLYL QLHGDLVRRL EPTERPLQIV YDYLSRLGFD DPVRIQEEAT 120

DPDLGCMLRF YGEKPCQMDH LDRILLSGIY NVRKGKTQLH KWAERLVVLC GTCLIVSSVK 180

DCQTGKMHIL PLVGGKVEEV KRRQHSLAFS SAGAQAQTYH VSFETLAECQ RWQRQASKVV 240

SQRISTVDLS CYSLEEVPEH LFYSQDITYL NLRHNFMQLE RPGGLDTLYR FSQLKGLNLS 300

HNKLGLFPVL LCEISTLTEL NLSCNGIHDL PSQIGSLLNL QTLCLDGNFL TTLPEELGNL 360

QQLSSLGISF NNFSQIPEVY EKLSMLDKVV MAGNRLEVLK LGVLSRMSHI RHVDFRMNHL 420

KTVVTENLEG NKYITHMDLR DNQLSDLDLS SLCSLEQLHC ERNQLRELTL SGFSLRMLYA 480

SSNRLTAVNV YPVPSQLTSL ELSRNLLECV PDWACEAKKM EILDVSYNLL TEVPLRILSS 540

LSLRKLMVGH NQVQSLPVLA EHIPLEALDI QHNLLTRLPD TLFSKALNLR YLNASANSLE 600

SLPSAGAGEE SLSALQLLYL TNNLLTDQCV PVLVGHPHLR ILHLANNQLQ TFPASKLNKL 660

EQLEELNLSG NKLKTIPTTI ANCKRLHTLV AHSNNISIFP EILQLPQIQF VDLSCNDLTE 720

ILIPEALPAT LQDLDLTGNT NLVLEHKTLD TFSHITTLKI DQKPLPTTDA TLTSTFWSHG 780

LAEMAGQRNK LCVSALAVDN FAEGVGAVYG MFDGDRNEEL PRLLQCTMAD VLLEEVQQST 840

NDTVFMANTF LVSHRKLGMA GQKLGSSALL CYIRPDTADP TSSFSLTVAN VGTCQAVLCR 900

SGKPVPLSKV FSLEQDPEEA QRVKDQKAII TEDNKVNGVT CCTRMLGCTY LYPWILPKPH 960

ISATPLTIQD ELLILGNKAL WEYLSYTEAV DAVRHVQDPL AAAKKLCTLA QSYGCQDNVG 1020

AMVVYLNIGE EGCTCEMNGL TLPGPVGFAS TTVLKDPPKP TTPSSSSGIA SEFGSEMSTS 1080

EVSSEVGSTA SDEHNTVGLD AGLLPRPERR CSLHPTPTSA LFQRQPSCAT FSSNQSDNGL 1140

DSDDDQPVEG VITNGSKVEV EVDIHCCRGR DLENSPTLRE NSPTPCPEEH ARGSFFGIRR 1200

QNSVNSGILV PGSKDRMELQ KSPSTSCLYG KKLSNGSIVP LEDSLNLIEV ATEAPKKKTG 1260

YFAAPTQLEP EDQFVVPRDL EEEVKEQMKQ HQESRPEPEP HEEDRTELPE EFDTAL 1316

Nucleotide Sequence
(FASTA)

ATGAAACGCA ATGGGAGCAG GAATTGTTTG AATAGGCGGA GTAGGTTTGG TTCTCGAGAA 60

AGAGACTGGC TGAGAGAAGA TGTCAGGAGG GGTTGTGTGT ACCTGTATGG CGCCGACTCG 120

ACCACTGCCA CCGCCAGCGC TTCTGCCTCC GCCTCCTCCG ACTTGCATCT GGTTCTGTGC 180

ACTGTGGAGA CGCCAGCATC AGAGATCTGT GCCGGAGAGG GAAGGGAAAG TCTTTATTTA 240

CAGCTTCATG GGGACCTGGT CAGGAGACTG GAACCTACTG AACGACCTCT TCAGATTGTG 300

TATGATTACT TATCCAGGCT GGGATTTGAT GACCCTGTGC GTATACAGGA GGAGGCAACA 360

GATCCTGACC TTGGCTGTAT GCTTCGATTT TATGGTGAAA AACCATGCCA GATGGATCAT 420

CTGGATCGAA TCCTTCTGTC TGGCATCTAT AATGTACGCA AGGGAAAGAC CCAGCTGCAT 480

AAGTGGGCTG AACGCCTAGT TGTTCTCTGT GGGACGTGCC TCATCGTTTC CTCGGTGAAG 540

GATTGTCAGA CTGGGAAGAT GCACATTTTG CCTCTGGTTG GGGGAAAGGT GGAAGAAGTG 600

AAGCGAAGGC AGCACTCCCT GGCGTTCAGC TCAGCTGGAG CCCAAGCTCA GACCTATCAC 660

GTCAGCTTTG AGACGCTGGC CGAGTGCCAG AGATGGCAGC GACAGGCATC CAAGGTGGTG 720

TCCCAGCGAA TCAGCACTGT TGACCTGTCA TGTTACAGCC TTGAGGAGGT TCCTGAGCAT 780

CTCTTCTACA GTCAAGATAT CACCTACCTC AATTTGCGAC ATAATTTTAT GCAGTTGGAA 840

AGACCTGGGG GCCTTGACAC TCTCTACAGA TTTTCTCAGC TGAAGGGCCT AAACTTGTCC 900

CATAATAAAC TTGGTTTGTT TCCTGTATTG TTATGTGAGA TTTCTACCCT CACTGAGCTC 960

AACCTCTCCT GTAACGGAAT TCATGACCTG CCGAGTCAGA TTGGCAGTCT GCTAAATCTT 1020

CAAACCCTCT GTCTTGATGG CAACTTTCTG ACAACTTTAC CGGAAGAATT GGGAAATCTG 1080

CAACAGCTTT CTTCCCTGGG AATTTCCTTT AACAACTTCA GTCAAATTCC AGAGGTTTAT 1140

GAGAAACTCA GTATGTTAGA TAAAGTGGTT ATGGCGGGAA ATCGCCTGGA AGTCCTAAAA 1200

CTTGGGGTTC TGAGCAGGAT GAGCCATATC AGACATGTGG ATTTCAGGAT GAACCATTTG 1260

AAAACTGTGG TTACGGAAAA TCTGGAGGGA AATAAGTACA TCACTCATAT GGATCTGCGG 1320

GACAATCAAC TGTCTGACTT AGATCTTAGC TCCTTGTGTA GCTTGGAGCA GCTGCACTGT 1380

GAACGGAACC AGCTGCGAGA GCTGACGCTC AGTGGCTTCT CCCTCCGAAT GCTCTACGCC 1440

AGTTCCAACA GGCTGACAGC AGTGAATGTC TATCCAGTAC CCAGTCAACT CACTTCTTTA 1500

GAACTTTCCC GAAACCTGCT AGAGTGTGTC CCTGACTGGG CCTGTGAAGC AAAGAAGATG 1560

GAAATATTAG ATGTGAGCTA TAATCTTCTG ACAGAGGTTC CCTTGAGAAT CCTTAGTAGC 1620

TTGAGTCTCA GAAAGCTAAT GGTGGGGCAC AACCAGGTGC AGAGCCTCCC GGTGCTGGCG 1680

GAGCACATCC CTTTGGAGGC GCTGGATATT CAGCATAACC TGCTCACCAG GCTGCCAGAT 1740

ACGCTCTTCT CCAAGGCCTT AAATCTCAGA TACTTGAATG CATCTGCAAA CAGTCTGGAA 1800

TCTTTGCCAT CTGCTGGCGC TGGAGAGGAG AGTCTGAGTG CTCTGCAGCT GCTCTATCTG 1860

ACCAACAACC TCCTGACAGA CCAGTGTGTG CCTGTTCTGG TGGGCCACCC GCACCTGCGG 1920

ATCCTGCATC TTGCCAACAA CCAGCTACAG ACCTTTCCTG CAAGCAAACT AAATAAATTG 1980

GAGCAGTTGG AAGAACTGAA CCTAAGTGGC AACAAGCTTA AAACCATTCC CACGACCATA 2040

GCCAACTGCA AAAGGCTTCA CACCCTTGTG GCGCACTCCA ACAACATCAG TATTTTCCCA 2100

GAGATACTGC AGTTGCCTCA GATCCAGTTT GTAGACCTAA GTTGCAATGA CTTGACAGAA 2160

ATCCTGATTC CTGAGGCTCT GCCTGCTACT TTACAAGACC TTGACCTGAC TGGAAATACA 2220

AATCTGGTTC TGGAACACAA GACGCTGGAC ACATTTAGCC ATATCACCAC CTTGAAAATT 2280

GACCAGAAAC CTTTGCCAAC CACCGATGCT ACACTTACAT CAACCTTCTG GAGCCATGGA 2340

CTGGCTGAGA TGGCAGGGCA GAGAAATAAG CTGTGTGTCT CTGCCCTGGC TGTGGATAAC 2400

TTTGCAGAGG GGGTGGGCGC GGTATACGGC ATGTTTGACG GGGACCGGAA CGAGGAGCTC 2460

CCTCGCCTGC TCCAGTGTAC CATGGCGGAC GTGCTTTTGG AAGAAGTGCA GCAGTCAACA 2520

AATGACACGG TGTTCATGGC TAACACCTTC TTGGTATCTC ACAGGAAATT GGGAATGGCC 2580

GGCCAGAAGC TGGGCTCCTC CGCTCTCCTT TGTTACATCC GCCCCGACAC TGCCGACCCA 2640

ACAAGTAGTT TCAGCCTGAC TGTAGCCAAC GTTGGCACGT GCCAAGCGGT CCTGTGCCGC 2700

AGTGGGAAGC CAGTGCCCCT CTCGAAAGTC TTCAGCCTGG AGCAGGACCC AGAGGAGGCT 2760

CAAAGGGTGA AGGACCAGAA AGCCATCATA ACAGAGGACA ACAAAGTGAA CGGGGTAACC 2820

TGCTGTACCC GGATGCTGGG CTGTACATAC CTCTACCCTT GGATCCTCCC TAAACCCCAC 2880

ATATCTGCCA CTCCACTTAC CATTCAAGAT GAGTTGCTGA TTCTGGGAAA CAAAGCATTG 2940

TGGGAATACC TGTCATACAC AGAAGCTGTC GACGCAGTAC GCCATGTACA GGACCCATTA 3000

GCAGCTGCCA AGAAGCTGTG CACGTTAGCC CAGAGCTATG GTTGTCAGGA CAATGTGGGG 3060

GCGATGGTGG TTTATTTGAA CATTGGAGAG GAAGGGTGCA CGTGTGAAAT GAATGGGCTC 3120

ACTCTCCCAG GTCCTGTGGG ATTTGCTTCA ACCACTGTCC TCAAGGACCC CCCCAAGCCA 3180

ACCACTCCTT CCTCCAGCAG TGGCATTGCC TCTGAGTTCG GCAGCGAGAT GTCCACCTCA 3240

GAGGTGAGCA GCGAGGTGGG GTCCACCGCT TCTGATGAAC ACAACACTGT CGGGCTGGAT 3300

GCTGGCTTGC TTCCAAGGCC GGAGAGGCGC TGCAGCCTCC ACCCAACACC CACCTCCGCG 3360

CTCTTTCAGC GCCAGCCTTC TTGTGCGACT TTCTCAAGTA ACCAGTCTGA CAATGGCCTG 3420

GACAGCGATG ACGACCAGCC TGTCGAAGGT GTCATAACAA ATGGCAGCAA AGTAGAAGTC 3480

GAAGTAGATA TCCACTGCTG TCGGGGAAGG GATCTCGAGA ACTCTCCCAC TCTGAGAGAG 3540

AATTCTCCTA CCCCGTGTCC TGAGGAACAT GCTAGAGGAT CGTTTTTTGG GATCCGAAGA 3600

CAGAACAGTG TGAATAGTGG CATACTTGTG CCAGGGAGCA AGGACAGGAT GGAGTTACAG 3660

AAGTCCCCCT CCACTTCCTG TCTGTACGGA AAGAAACTCT CGAATGGCTC TATCGTGCCC 3720

CTAGAAGATA GCCTGAACCT CATTGAAGTG GCCACAGAAG CACCCAAGAA GAAGACTGGC 3780

TACTTTGCTG CCCCGACTCA GCTGGAGCCG GAGGATCAGT TTGTTGTACC TCGTGACCTG 3840

GAGGAAGAAG TCAAAGAGCA AATGAAGCAA CACCAGGAAA GTAGACCCGA GCCTGAGCCC 3900

CACGAAGAGG ATCGGACCGA GCTCCCGGAG GAGTTTGACA CGGCCCTGTA A 3951

Domain Profile

S: 2     lvgvvsvngrrnemedavtsspnflkspekkdrlaffgvyDGhggsevakfcseklheil  61

         ++g++++ g+rn+++ ++ +++nf++  +     a++g++DG++++e  + +++++ ++l

Q: 778   SHGLAEMAGQRNKLCVSALAVDNFAEGVG-----AVYGMFDGDRNEELPRLLQCTMADVL  832

         6899*********************9877.....59************************

S: 62    aeelesseseerkvkkalakaFlstdeelkvleeksldidksGstavvalikds......  115

          ee++    ++++ + ++a++Fl  +++l       ++ +k Gs+a++++i+++

Q: 833   LEEVQ----QSTNDTVFMANTFLVSHRKL------GMAGQKLGSSALLCYIRPDtadpts  882

         ***99....77888889************......89***************999999**

S: 116   ..klyvanvGdSravLcrngkavelssdHkpsre.dEleRieeaggsvilkdgaRvlGvL  172

           +l+vanvG ++avLcr+gk+v+ls+ ++ +++ +E +R++++++ +++++  +v+Gv+

Q: 883   sfSLTVANVGTCQAVLCRSGKPVPLSKVFSLEQDpEEAQRVKDQKAIITEDN--KVNGVT  940

         ******************************99866**********9999998..******

S: 173   avsRalGdlylkpyvtpePevtshrltsedefliLasDGlwdvvsneeavslvrdvlekk  232

         +++R+lG++yl+p++ p+P+++ ++lt +de liL+ + lw+++s  eav++vr+v +

Q: 941   CCTRMLGCTYLYPWILPKPHISATPLTIQDELLILGNKALWEYLSYTEAVDAVRHVQD--  998

         **********************************************************..

S: 233   eaeqeaakkLvklalargskdnvsaivv  260

           + +aakkL++la+++g++dnv a+vv

Q: 999   --PLAAAKKLCTLAQSYGCQDNVGAMVV  1024

         ..************************97

Domain Sequence
(FASTA)

SHGLAEMAGQ RNKLCVSALA VDNFAEGVGA VYGMFDGDRN EELPRLLQCT MADVLLEEVQ 60

QSTNDTVFMA NTFLVSHRKL GMAGQKLGSS ALLCYIRPDT ADPTSSFSLT VANVGTCQAV 120

LCRSGKPVPL SKVFSLEQDP EEAQRVKDQK AIITEDNKVN GVTCCTRMLG CTYLYPWILP 180

KPHISATPLT IQDELLILGN KALWEYLSYT EAVDAVRHVQ DPLAAAKKLC TLAQSYGCQD 240

NVGAMVV 247

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Danio rerio"; ?>Equus caballus"; ?>Felis catus"; ?>Gadus morhua"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Ictidomys tridecemlineatus"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Ochotona princeps"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sarcophilus harrisii"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Tursiops truncatus"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>Saccharomyces cerevisiae"; ?>Schizosaccharomyces pombe"; ?>