EKS-MUP-00294

Eukaryotic Protein Kinase & Protein Phosphatase Database

Tag

Content

EKPD ID

EKS-MUP-00294

Classification

Group/Family	Score	E-Value	Start	End	Domain Length
TK/EGFR	502.6	1.9E-151	634	891	258

Status

Unreviewed

Ensembl Protein

ENSMPUP00000007834

Gene Name

ERBB4

Gene Synonyms/Alias

Ensembl Information

Ensembl Gene ID	Ensembl Protein ID	Ensembl Transcript ID
ENSMPUG00000007892	ENSMPUP00000007834	ENSMPUT00000007959

Organism

Mustela putorius furo

Protein Length

1224

Protein Sequence
(FASTA)

MGNLEITSIE HNRDLSFLRS IREVTGYVLV ALNQFRYLPL ENLRIIRGTK LYEDRYALAV 60

FLNYRKDGNF GLQELGLKNL TEILNGGVYV DQNKFLCYTD TIHWQDIVRN PWPSNLTLVS 120

TNGSSGCGRC HKSCTGRCWG PTENHCQTLT RTVCAEQCDG RCYGPYVSDC CHRECAGGCS 180

GPKDTDCFAC MNFNDSGACV TQCPQTFVYN PTTFQLEHNF NAKYTYGAFC VKKCPHNFVV 240

DSSSCVRACP SSKMEVEENG IKMCKPCTDI CPKACDGIGT GSLMSAQTVD SSNIDKFVNC 300

TKINGNLIFL VTGIHGDPYN AIEAIDPEKL NVFRTVREIT GFLNIQSWPP NMTDFSVFSN 360

LVTIGGRVLY SGLSLLILKQ QGITSLQFQS LKEISAGNIY ITDNSNLCYY HTINWTALFS 420

TINQRIVIRD NRKAENCTAE GMVCNHLCSG DGCWGPGPDQ CLSCRRFSRG RSCIESCNLY 480

DGEFREFENG SICVECDPQC EKMEDGILTC HGPGPDNCTK CSHFKDGPNC VEKCPDGLQG 540

TNSFIFKYAD QDRECHPCHP NCTQGTPLIA AGVIGGLFIL VIVGLTFAVY VRRKSIKKKR 600

ALRRFLETEL VEPLTPSGTA PNQAQLRILK ETELKRVKVL GSGAFGTVYK GIWVPEGETV 660

KIPVAIKILN ETTGPKANVE FMDEALIMAS MDHPHLVRLL GVCLSPTIQL VTQLMPHGCL 720

LDYVHEHKDN IGSQLLLNWC VQIAKGMMYL EERRLVHRDL AARNVLVKSP NHVKITDFGL 780

ARLLEGDEKE YNADGGKMPI KWMALECIHY RKFTHQSDVW SYGVTIWELM TFGGKPYDGI 840

PTREIPDLLE KGERLPQPPI CTIDVYMVMV KCWMIDADSR PKFKELAAEF SRMARDPQRY 900

LVIQGDDRMK LPSPNDSKFF QNLLDEEDLE DMMDAEEYLV PQAFNIPPPI YTSRARIDSN 960

RSEIGHSPPP AYTPMSGNQF VYRDGGFAAE QGVPVPYRAT TSTIPEAPLA QGATAEIFDD 1020

SCCNGTLRKP AAPHVQEDSS TQRYSADPTV FAPERSPRGE LDEEGYMTPM RDKPKQEYLN 1080

PVEENPFVSR RKNGDLQALD NPEYHNASNG PPKAEDEYVN EPLYLNTFAN ALGNAEYLKN 1140

NVLSVPEKAK KAFDNPDYWN HSLPPRSTLQ HPDYLQEYST KYFYKQNGRI RPIVAENPEY 1200

LSEFSLKPGT VLPPPPYRHR NTVV 1224

Nucleotide Sequence
(FASTA)

ATGGGCAACC TGGAGATAAC CAGCATCGAG CACAACCGGG ACCTCTCCTT TCTGCGGTCT 60

ATTCGAGAAG TCACAGGCTA TGTGTTAGTG GCTCTTAATC AGTTTCGTTA CCTGCCGCTG 120

GAGAACTTGC GCATTATCCG TGGGACAAAA CTGTATGAGG ATCGATATGC CTTGGCAGTA 180

TTTTTAAACT ATAGAAAAGA TGGGAACTTT GGACTTCAAG AACTTGGACT GAAGAACTTG 240

ACAGAAATCC TTAATGGTGG AGTGTATGTA GACCAGAACA AATTTCTTTG TTACACAGAC 300

ACAATTCATT GGCAAGATAT TGTTCGGAAT CCATGGCCTT CCAACCTGAC TCTGGTGTCA 360

ACAAATGGTA GCTCAGGATG TGGACGTTGT CATAAGTCCT GTACTGGCCG ATGCTGGGGA 420

CCCACAGAAA ACCATTGCCA GACCTTGACA AGGACGGTGT GTGCAGAACA GTGTGATGGC 480

AGGTGCTATG GGCCCTATGT CAGTGACTGC TGTCATAGAG AATGTGCTGG GGGCTGCTCG 540

GGACCCAAGG ACACAGACTG TTTTGCCTGC ATGAATTTCA ATGACAGTGG AGCATGTGTT 600

ACTCAGTGTC CCCAAACTTT TGTCTACAAT CCTACCACTT TTCAACTGGA GCATAACTTC 660

AATGCAAAGT ATACATATGG AGCATTTTGT GTCAAGAAAT GTCCCCATAA CTTTGTGGTG 720

GATTCCAGTT CTTGCGTACG TGCCTGCCCT AGTTCCAAGA TGGAAGTAGA AGAAAATGGG 780

ATTAAAATGT GTAAACCTTG CACGGATATT TGCCCAAAAG CTTGTGATGG CATTGGCACA 840

GGATCACTGA TGTCAGCTCA GACCGTGGAT TCTAGTAACA TTGACAAATT CGTAAACTGC 900

ACCAAAATCA ATGGGAATTT GATCTTCCTT GTCACTGGTA TTCATGGGGA CCCTTACAAT 960

GCAATTGAAG CCATAGACCC AGAGAAACTG AATGTCTTCC GGACAGTTCG AGAGATAACA 1020

GGTTTCTTGA ACATACAGTC ATGGCCCCCA AACATGACCG ACTTCAGTGT TTTTTCTAAC 1080

CTGGTGACCA TCGGTGGAAG AGTACTCTAT AGTGGCCTCT CCTTGCTTAT CCTTAAGCAA 1140

CAGGGCATCA CCTCTCTACA ATTCCAATCT CTGAAGGAAA TCAGTGCGGG AAATATCTAT 1200

ATTACTGACA ACAGCAACCT GTGTTATTAT CACACCATTA ACTGGACAGC ACTCTTCAGC 1260

ACCATCAACC AAAGGATAGT GATCCGGGAC AATAGGAAAG CTGAGAACTG TACTGCTGAA 1320

GGAATGGTGT GCAACCATCT GTGCTCAGGC GATGGCTGTT GGGGACCTGG CCCCGACCAG 1380

TGCCTGTCCT GCCGTCGTTT CAGCAGAGGA AGGAGCTGCA TTGAGTCTTG TAACCTCTAT 1440

GATGGGGAAT TTCGAGAGTT TGAGAATGGC TCCATCTGTG TGGAGTGTGA CCCCCAGTGT 1500

GAGAAGATGG AAGACGGCAT CCTCACCTGC CATGGACCGG GACCTGACAA CTGCACAAAG 1560

TGCTCCCATT TTAAGGATGG CCCGAACTGT GTGGAAAAAT GTCCAGATGG TTTACAGGGG 1620

ACAAACAGTT TCATTTTCAA GTATGCTGAT CAGGATCGAG AATGTCACCC ATGTCATCCA 1680

AACTGCACCC AAGGAACTCC TCTGATTGCA GCAGGAGTCA TCGGTGGGCT CTTCATCCTG 1740

GTCATCGTGG GCCTAACATT TGCAGTTTAT GTTAGAAGGA AGAGCATCAA AAAGAAAAGA 1800

GCCTTAAGAA GATTCCTGGA AACAGAGTTG GTAGAACCTT TAACTCCCAG TGGTACTGCA 1860

CCCAATCAAG CTCAACTTCG TATTTTGAAA GAAACTGAGC TCAAAAGAGT GAAAGTACTT 1920

GGCTCAGGTG CTTTTGGAAC AGTTTATAAG GGCATTTGGG TACCTGAAGG AGAAACAGTA 1980

AAGATTCCTG TGGCTATTAA GATTCTTAAT GAAACAACTG GTCCCAAAGC CAATGTGGAG 2040

TTCATGGATG AAGCTTTGAT CATGGCAAGT ATGGACCATC CACACTTAGT CCGGTTATTG 2100

GGTGTGTGTC TGAGCCCAAC CATTCAGCTG GTTACACAGC TTATGCCCCA TGGATGCCTG 2160

TTGGATTATG TCCATGAACA CAAGGATAAC ATTGGATCCC AGCTGCTGCT TAACTGGTGT 2220

GTCCAGATAG CTAAGGGAAT GATGTACTTG GAAGAAAGAC GGCTTGTTCA TCGGGATTTA 2280

GCAGCCCGAA ATGTCTTAGT GAAATCTCCA AACCATGTGA AAATCACAGA TTTTGGACTA 2340

GCCAGACTCT TAGAAGGAGA TGAAAAAGAA TATAATGCTG ATGGAGGAAA GATGCCAATT 2400

AAATGGATGG CTCTGGAGTG TATACATTAC AGAAAATTTA CCCATCAGAG TGATGTTTGG 2460

AGCTATGGAG TCACTATATG GGAACTGATG ACCTTTGGAG GAAAACCATA TGATGGAATT 2520

CCAACCCGAG AAATCCCAGA TTTATTAGAG AAAGGAGAAC GTTTGCCCCA GCCTCCGATC 2580

TGCACTATTG ACGTTTACAT GGTCATGGTC AAATGTTGGA TGATTGATGC TGACAGTAGA 2640

CCTAAATTTA AGGAACTGGC TGCTGAATTT TCGAGGATGG CTCGAGACCC TCAAAGATAC 2700

CTAGTTATTC AGGGTGATGA TCGCATGAAG CTTCCCAGTC CAAACGACAG CAAGTTCTTT 2760

CAGAATCTCT TGGATGAAGA GGATTTGGAA GACATGATGG ATGCTGAGGA GTACCTGGTC 2820

CCTCAGGCTT TCAACATCCC ACCTCCCATC TACACTTCCA GAGCAAGAAT TGACTCAAAT 2880

AGGAGTGAAA TTGGACACAG CCCTCCTCCT GCCTACACCC CCATGTCAGG AAACCAGTTT 2940

GTATACCGAG ATGGGGGGTT TGCTGCCGAG CAAGGAGTGC CTGTGCCCTA CAGAGCCACA 3000

ACCAGCACGA TCCCAGAAGC ACCACTTGCT CAGGGGGCTA CAGCCGAGAT TTTTGATGAC 3060

TCCTGTTGTA ACGGCACCCT ACGCAAGCCA GCGGCACCCC ATGTCCAGGA GGATAGCAGC 3120

ACCCAGAGGT ACAGCGCTGA CCCCACAGTG TTTGCCCCGG AACGGAGCCC ACGAGGAGAG 3180

CTGGATGAAG AGGGTTACAT GACCCCTATG CGAGATAAAC CTAAACAAGA ATACCTGAAC 3240

CCTGTGGAGG AGAACCCTTT TGTTTCTCGG AGGAAAAACG GAGACCTTCA AGCTTTGGAT 3300

AATCCCGAAT ATCACAACGC TTCCAATGGT CCACCCAAGG CAGAGGATGA GTATGTGAAT 3360

GAGCCACTGT ACCTCAACAC CTTTGCCAAC GCATTGGGGA ATGCCGAGTA CCTGAAGAAC 3420

AATGTACTGT CTGTGCCAGA GAAGGCCAAG AAAGCATTCG ACAACCCTGA CTACTGGAAC 3480

CACAGCCTGC CACCTCGCAG CACCCTTCAA CACCCAGACT ACCTGCAGGA GTACAGCACA 3540

AAATATTTTT ATAAACAAAA TGGACGGATC CGGCCTATTG TGGCAGAGAA TCCTGAATAC 3600

CTCTCTGAGT TCTCGCTGAA GCCCGGCACT GTGCTGCCTC CTCCACCCTA CAGACACCGA 3660

AATACTGTGG TGTAA 3675

Domain Profile

S: 1     lkklkvlGsGafGtvykGiwipegenvkipvaikvleektgkkankelldealvlasldh  60

         lk++kvlGsGafGtvykGiw+pege+vkipvaik+l+e+tg+kan e++deal++as+dh

Q: 634   LKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDH  693

         699*********************************************************

S: 61    anlvrllglclsstlqlvtqllplGclldyvrehkdklGsqellnwcvqiakGmsyleek  120

         ++lvrllg+cls t+qlvtql+p+Gclldyv+ehkd++Gsq llnwcvqiakGm+ylee+

Q: 694   PHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEER  753

         ************************************************************

S: 121   rlvhrdlaarnvlvkspnhvkitdfGlaklleadekelkaeggkvpikwlalesilkrky  180

         rlvhrdlaarnvlvkspnhvkitdfGla+lle deke++a+ggk+pikw+ale+i++rk+

Q: 754   RLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKF  813

         ************************************************************

S: 181   thqsdvwsyGvtvwelltfGakpydgipakeipdllekGerlaqppictidvymvlvkcw  240

         thqsdvwsyGvt+wel+tfG kpydgip++eipdllekGerl+qppictidvymv+vkcw

Q: 814   THQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCW  873

         ************************************************************

S: 241   midaesrpkfkelaeefs  258

         mida+srpkfkela+efs

Q: 874   MIDADSRPKFKELAAEFS  891

         ****************96

Domain Sequence
(FASTA)

LKRVKVLGSG AFGTVYKGIW VPEGETVKIP VAIKILNETT GPKANVEFMD EALIMASMDH 60

PHLVRLLGVC LSPTIQLVTQ LMPHGCLLDY VHEHKDNIGS QLLLNWCVQI AKGMMYLEER 120

RLVHRDLAAR NVLVKSPNHV KITDFGLARL LEGDEKEYNA DGGKMPIKWM ALECIHYRKF 180

THQSDVWSYG VTIWELMTFG GKPYDGIPTR EIPDLLEKGE RLPQPPICTI DVYMVMVKCW 240

MIDADSRPKF KELAAEFS 258

Keyword

Sequence Source

Ensembl

Orthology

Ortholog group

Ailuropoda melanoleuca"; ?>Anolis carolinensis"; ?>Bos taurus"; ?>Caenorhabditis elegans"; ?>Callithrix jacchus"; ?>Canis familiaris"; ?>Cavia porcellus"; ?>Equus caballus"; ?>Gallus gallus"; ?>Gasterosteus aculeatus"; ?>Gorilla gorilla"; ?>Homo sapiens"; ?>Latimeria chalumnae"; ?>Loxodonta africana"; ?>Macaca mulatta"; ?>Meleagris gallopavo"; ?>Monodelphis domestica"; ?>Mus musculus"; ?>Myotis lucifugus"; ?>Nomascus leucogenys"; ?>Oreochromis niloticus"; ?>Ornithorhynchus anatinus"; ?>Oryctolagus cuniculus"; ?>Oryzias latipes"; ?>Otolemur garnettii"; ?>Pan troglodytes"; ?>Pelodiscus sinensis"; ?>Petromyzon marinus"; ?>Pongo abelii"; ?>Rattus norvegicus"; ?>Sus scrofa"; ?>Taeniopygia guttata"; ?>Takifugu rubripes"; ?>Tetraodon nigroviridis"; ?>Vicugna pacos"; ?>Xenopus tropicalis"; ?>Xiphophorus maculatus"; ?>